Published in Biochim Biophys Acta on January 30, 2002
Epigenomic profiling reveals DNA-methylation changes associated with major psychosis. Am J Hum Genet (2008) 4.71
Intra- and interindividual epigenetic variation in human germ cells. Am J Hum Genet (2006) 2.79
Calcium-dependent molecular spring elements in the giant protein titin. Proc Natl Acad Sci U S A (2003) 2.16
Tibial muscular dystrophy is a titinopathy caused by mutations in TTN, the gene encoding the giant skeletal-muscle protein titin. Am J Hum Genet (2002) 2.14
Primary ciliary dyskinesia associated with normal axoneme ultrastructure is caused by DNAH11 mutations. Hum Mutat (2008) 2.03
Age-specific epigenetic drift in late-onset Alzheimer's disease. PLoS One (2008) 2.01
Anemia and inflammation in COPD. Chest (2005) 1.83
Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2013) 1.79
Mutations and deletions of the TP53 gene predict nonresponse to treatment and poor outcome in first relapse of childhood acute lymphoblastic leukemia. J Clin Oncol (2011) 1.61
Anorexia in chronic obstructive pulmonary disease--association to cachexia and hormonal derangement. Int J Cardiol (2006) 1.58
Automatic pressure titration with APAP is as effective as manual titration with CPAP in patients with obstructive sleep apnea. Respiration (2007) 1.57
Zebrafish embryos as an alternative to animal experiments--a commentary on the definition of the onset of protected life stages in animal welfare regulations. Reprod Toxicol (2011) 1.51
Nebulin alters cross-bridge cycling kinetics and increases thin filament activation: a novel mechanism for increasing tension and reducing tension cost. J Biol Chem (2009) 1.41
Associations of daily walking activity with biomarkers related to cardiac distress in patients with chronic obstructive pulmonary disease. Respiration (2012) 1.38
High expression levels of x-linked inhibitor of apoptosis protein and survivin correlate with poor overall survival in childhood de novo acute myeloid leukemia. Clin Cancer Res (2004) 1.36
Lung Transplantation in Germany Since the Introduction of the Lung Allocation Score. Dtsch Arztebl Int (2017) 1.34
Automated in-silico detection of cell populations in flow cytometry readouts and its application to leukemia disease monitoring. BMC Bioinformatics (2006) 1.29
Standardization of flow cytometric minimal residual disease evaluation in acute lymphoblastic leukemia: Multicentric assessment is feasible. Cytometry B Clin Cytom (2008) 1.22
Bronchoscopic thermal vapour ablation therapy in the management of heterogeneous emphysema. Eur Respir J (2011) 1.22
Apoptosis and necrosis induced by cyclic mechanical stretching in alveolar type II cells. Am J Respir Cell Mol Biol (2003) 1.20
Right ventricular function assessed by two-dimensional strain and tissue Doppler echocardiography in patients with pulmonary arterial hypertension and effect of vasodilator therapy. Am J Cardiol (2006) 1.20
Novel types of mutation responsible for the dermatosparactic type of Ehlers-Danlos syndrome (Type VIIC) and common polymorphisms in the ADAMTS2 gene. J Invest Dermatol (2004) 1.16
Characterization of outcomes 1 year after endoscopic thermal vapor ablation for patients with heterogeneous emphysema. Int J Chron Obstruct Pulmon Dis (2012) 1.15
Randomized comparison of enoxaparin with unfractionated heparin for the prevention of venous thromboembolism in medical patients with heart failure or severe respiratory disease. Am Heart J (2003) 1.15
The Pharmacological Treatment of Chronic Obstructive Pulmonary Disease. Dtsch Arztebl Int (2016) 1.12
SHOX2 DNA methylation is a biomarker for the diagnosis of lung cancer based on bronchial aspirates. BMC Cancer (2010) 1.12
Distribution of respiratory mucin proteins in human nasal mucosa. Laryngoscope (2003) 1.11
MuRF1 is a muscle fiber-type II associated factor and together with MuRF2 regulates type-II fiber trophicity and maintenance. J Struct Biol (2010) 1.10
Adult patients with congenital heart disease and pulmonary arterial hypertension: first open prospective multicenter study of bosentan therapy. Am Heart J (2005) 1.09
XIAP expression correlates with monocytic differentiation in adult de novo AML: impact on prognosis. Hematol J (2004) 1.07
Influence of basic fibroblast growth factor on the proliferation of non-small cell lung cancer cell lines. Lung Cancer (2004) 1.07
Efficacy of bronchoscopic thermal vapor ablation and lobar fissure completeness in patients with heterogeneous emphysema. Respiration (2012) 1.06
Prevalence of anemia in chronic obstructive pulmonary disease: comparison to other chronic diseases. Int J Cardiol (2005) 1.02
Bimosiamose, an inhaled small-molecule pan-selectin antagonist, attenuates late asthmatic reactions following allergen challenge in mild asthmatics: a randomized, double-blind, placebo-controlled clinical cross-over-trial. Pulm Pharmacol Ther (2005) 1.01
Substance P expression in TRPV1 and trkA-positive dorsal root ganglion neurons innervating the mouse lung. Respir Physiol Neurobiol (2004) 1.01
Bronchoalveoloar lavage fluid cytokines and chemokines as markers and predictors for the outcome of interstitial lung disease in systemic sclerosis patients. Arthritis Res Ther (2009) 1.01
A high-throughput DNA methylation analysis of a single cell. Nucleic Acids Res (2011) 1.00
Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy. J Clin Invest (2010) 0.99
Expression of distinct classes of titin isoforms in striated and smooth muscles by alternative splicing, and their conserved interaction with filamins. J Mol Biol (2006) 0.99
Multiplex analysis of cytokines in exhaled breath condensate. Cytometry A (2006) 0.99
The localized inflammatory response to bronchoscopic thermal vapor ablation. Respiration (2013) 0.97
Stretch-induced alveolar type II cell apoptosis: role of endogenous bradykinin and PI3K-Akt signaling. Am J Respir Cell Mol Biol (2007) 0.96
Pulmonary hypertension due to chronic lung disease: updated Recommendations of the Cologne Consensus Conference 2011. Int J Cardiol (2011) 0.95
Mechanical stretch alters alveolar type II cell mediator release toward a proinflammatory pattern. Am J Respir Cell Mol Biol (2005) 0.94
Nondirectiveness and genetic counseling. J Genet Couns (1995) 0.94
High interleukin-15 expression characterizes childhood acute lymphoblastic leukemia with involvement of the CNS. J Clin Oncol (2007) 0.94
Assisted reproductive techniques in patients with Klinefelter syndrome: a critical review. Fertil Steril (2004) 0.93
Modulation of antigen expression in B-cell precursor acute lymphoblastic leukemia during induction therapy is partly transient: evidence for a drug-induced regulatory phenomenon. Results of the AIEOP-BFM-ALL-FLOW-MRD-Study Group. Cytometry B Clin Cytom (2010) 0.93
Quantitative Brewster angle microscopy of the surface film of human broncho-alveolar lavage fluid. Eur Biophys J (2003) 0.93
Expression of late cell cycle genes and an increased proliferative capacity characterize very early relapse of childhood acute lymphoblastic leukemia. Clin Cancer Res (2006) 0.93
Cell cycle-controlled interaction of nucleolin with the retinoblastoma protein and cancerous cell transformation. J Biol Chem (2006) 0.92
A novel method for sensitive and specific detection of DNA methylation biomarkers based on DNA restriction during PCR cycling. Biotechniques (2009) 0.92
Novel mutations including deletions of the entire OFD1 gene in 30 families with type 1 orofaciodigital syndrome: a study of the extensive clinical variability. Hum Mutat (2012) 0.91
Mental health and quality of life after genetic testing for Huntington disease: a long-term effect study in Germany. Am J Med Genet A (2008) 0.91
Improved method for isolating cell-free DNA. Clin Chem (2005) 0.91
Pan-selectin antagonism improves psoriasis manifestation in mice and man. Arch Dermatol Res (2005) 0.90
Influence of tidal volume on pulmonary NO release, tissue lipid peroxidation and surfactant phospholipids. Biochim Biophys Acta (2003) 0.89
Time point-dependent concordance of flow cytometry and real-time quantitative polymerase chain reaction for minimal residual disease detection in childhood acute lymphoblastic leukemia. Haematologica (2012) 0.89
Molecular modeling of the myosin-S1(A1) isoform. J Struct Biol (2007) 0.88
Increased production of matrix metalloproteinase-2 in alveolar macrophages and regulation by interleukin-10 in patients with acute pulmonary sarcoidosis. Exp Lung Res (2002) 0.88
Bronchoscopic Coil Treatment for Patients with Severe Emphysema: A Meta-Analysis. Respiration (2015) 0.88
Integrity of cell-free plasma DNA in patients with lung cancer and nonmalignant lung disease. Ann N Y Acad Sci (2008) 0.87
Increased spontaneous interleukin-10 release from alveolar macrophages in active pulmonary sarcoidosis. Exp Lung Res (2003) 0.87
Rational design of novel, potent small molecule pan-selectin antagonists. J Med Chem (2007) 0.87
Long-term follow-up of a fenestrated Amplatzer atrial septal occluder in pulmonary arterial hypertension. Chest (2008) 0.86
Mobile Air Quality Studies (MAQS)-an international project. J Occup Med Toxicol (2010) 0.85
Cytochrome c-related caspase-3 activation determines treatment response and relapse in childhood precursor B-cell ALL. Blood (2006) 0.84
Effects of positive-pressure ventilation on the spontaneous baroreflex in healthy subjects. J Appl Physiol (1985) (2003) 0.84
Complement factor H is elevated in bronchoalveolar lavage fluid and sputum from patients with lung cancer. Cancer Epidemiol Biomarkers Prev (2010) 0.84
[Diagnostics and therapy of idiopathic pulmonary hemosiderosis]. Med Klin (Munich) (2007) 0.83
Release of bFGF following apoptosis and necrosis in NSCLC cells: effects on chemosensitivity to cisplatin. Oncol Rep (2005) 0.83
Do epigenetic pathways initiate late onset Alzheimer disease (LOAD): towards a new paradigm. Curr Alzheimer Res (2012) 0.83
Normal lymphocytes from leukemic samples as an internal quality control for fluorescence intensity in immunophenotyping of acute leukemias. Cytometry B Clin Cytom (2006) 0.83
Copy number alterations in childhood acute lymphoblastic leukemia and their association with minimal residual disease. Genes Chromosomes Cancer (2008) 0.83
Tele-monitoring reduces exacerbation of COPD in the context of climate change--a randomized controlled trial. Environ Health (2013) 0.83
Isolated hemoperfused slaughterhouse livers as a valid model to study hepatotoxicity. Toxicol Pathol (2003) 0.82
Drug delivery from the oral cavity: focus on a novel mechatronic delivery device. Drug Discov Today (2007) 0.82
Differences in the expression pattern of apoptosis-related molecules between childhood and adult de novo acute myeloid leukemia. Haematologica (2004) 0.82
Cloning, genomic structure, and expression profiles of TULIP1 (GARNL1), a brain-expressed candidate gene for 14q13-linked neurological phenotypes, and its murine homologue. Genomics (2004) 0.81
An intra-cerebral drug delivery system for freely moving animals. Biomed Microdevices (2012) 0.81
Adenovirus-mediated gene transfer of P16INK4/CDKN2 into bax-negative colon cancer cells induces apoptosis and tumor regression in vivo. Cancer Gene Ther (2002) 0.81
Hepatotoxic effects of polidocanol in a model of autologously perfused porcine livers. Arch Toxicol (2004) 0.81
High in comparison with low tidal volume ventilation aggravates oxidative stress-induced lung injury. Biochim Biophys Acta (2003) 0.80
Adaptations in titin's spring elements in normal and cardiomyopathic hearts. Adv Exp Med Biol (2003) 0.80
Enhanced expression of VEGF following bFGF inhibition in non-small cell lung cancer cell lines. Lung Cancer (2006) 0.80
Intact apoptosis signaling in myeloid leukemia cells determines treatment outcome in childhood AML. Blood (2007) 0.80
European respiratory society/american thoracic society/international association for the study of lung cancer international multidisciplinary classification of lung adenocarcinoma: state of the art. J Thorac Oncol (2011) 0.79
Quantification of free RNA in serum and bronchial lavage: a new diagnostic tool in lung cancer detection? Lung Cancer (2004) 0.79
Inhibition of chemokine production from human airway smooth muscle cells by fluticasone, budesonide and beclomethasone. Pulm Pharmacol Ther (2004) 0.78
Transcriptional down-regulation of neurotrophin-3 in chronic obstructive pulmonary disease. Biol Chem (2005) 0.78
CD11b is a therapy resistance- and minimal residual disease-specific marker in precursor B-cell acute lymphoblastic leukemia. Blood (2010) 0.78
Effects of inhaled HFA beclomethasone on pulmonary function and symptoms in patients with chronic obstructive pulmonary disease. Respir Med (2005) 0.78