Published in J Clin Invest on February 01, 2002
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Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma. Mol Cell (2013) 2.05
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A mouse model demonstrates a multigenic origin of congenital hypothyroidism. Endocrinology (2005) 1.89
Diiodothyropropionic acid (DITPA) in the treatment of MCT8 deficiency. J Clin Endocrinol Metab (2012) 1.85
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An integrated regulatory network controlling survival and migration in thyroid organogenesis. Dev Biol (2004) 1.55
Alterations in skin and stratified epithelia by constitutively activated PPARalpha. J Invest Dermatol (2006) 1.53
Impact of subclinical hypothyroidism in women with recurrent early pregnancy loss. Fertil Steril (2013) 1.50
The progenitor zone of the ventral medial ganglionic eminence requires Nkx2-1 to generate most of the globus pallidus but few neocortical interneurons. J Neurosci (2010) 1.48
The integrity of cholinergic basal forebrain neurons depends on expression of Nkx2-1. Eur J Neurosci (2011) 1.46
Thyroid hormone induces rapid activation of Akt/protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts. Mol Endocrinol (2004) 1.45
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Pten loss in the mouse thyroid causes goiter and follicular adenomas: insights into thyroid function and Cowden disease pathogenesis. Cancer Res (2007) 1.38
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Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways. Proc Natl Acad Sci U S A (2012) 1.31
A study of recurrence and death from papillary thyroid cancer with 27 years of median follow-up. Surgery (2013) 1.30
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Mice deficient in MCT8 reveal a mechanism regulating thyroid hormone secretion. J Clin Invest (2010) 1.28
A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism. Mol Endocrinol (2007) 1.27
Importance of monocarboxylate transporter 8 for the blood-brain barrier-dependent availability of 3,5,3'-triiodo-L-thyronine. Endocrinology (2009) 1.23
Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mice humanized for CYP1A1 and CYP1A2. Chem Res Toxicol (2005) 1.22
A thyroid hormone analog with reduced dependence on the monocarboxylate transporter 8 for tissue transport. Endocrinology (2009) 1.21
Type 3 deiodinase deficiency results in functional abnormalities at multiple levels of the thyroid axis. Endocrinology (2007) 1.21
Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors. Oncotarget (2011) 1.19
Hypothyroidism in thyroid transcription factor 1 haploinsufficiency is caused by reduced expression of the thyroid-stimulating hormone receptor. Mol Endocrinol (2003) 1.19
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Missense mutations of dual oxidase 2 (DUOX2) implicated in congenital hypothyroidism have impaired trafficking in cells reconstituted with DUOX2 maturation factor. Mol Endocrinol (2007) 1.17
A comprehensive investigation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) metabolism in the mouse using a multivariate data analysis approach. Chem Res Toxicol (2007) 1.17
Thyroid hormone action in the absence of thyroid hormone receptor DNA-binding in vivo. J Clin Invest (2003) 1.16
Decreased expression of uteroglobin-related protein 1 in inflamed mouse airways is mediated by IL-9. Am J Physiol Lung Cell Mol Physiol (2004) 1.16
Role of neutral amino acid transport and protein breakdown for substrate supply of nitric oxide synthase in human endothelial cells. Circ Res (2003) 1.15
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Determination of nuclear receptor corepressor interactions with the thyroid hormone receptor. Mol Endocrinol (2003) 1.13
Side population cells in the mouse thyroid exhibit stem/progenitor cell-like characteristics. Endocrinology (2007) 1.13
Deletion of the Ttf1 gene in differentiated neurons disrupts female reproduction without impairing basal ganglia function. J Neurosci (2006) 1.13
Thyroid hormone-regulated mouse cerebral cortex genes are differentially dependent on the source of the hormone: a study in monocarboxylate transporter-8- and deiodinase-2-deficient mice. Endocrinology (2010) 1.13
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The nuclear receptor corepressor (NCoR) controls thyroid hormone sensitivity and the set point of the hypothalamic-pituitary-thyroid axis. Mol Endocrinol (2011) 1.10
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Changes in thyroid status during perinatal development of MCT8-deficient male mice. Endocrinology (2013) 1.09
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Aberrant trajectory of ascending dopaminergic pathway in mice lacking Nkx2.1. Exp Neurol (2003) 1.08
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Regression of a large goiter in a patient with resistance to thyroid hormone by every other day treatment with triiodothyronine. Thyroid (2004) 1.07
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A common regulatory region functions bidirectionally in transcriptional activation of the human CYP1A1 and CYP1A2 genes. Mol Pharmacol (2006) 1.06
The interaction between nuclear receptor corepressor and histone deacetylase 3 regulates both positive and negative thyroid hormone action in vivo. Mol Endocrinol (2010) 1.05
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