Published in BMJ on March 02, 2002
Screening for depression in medical settings with the Patient Health Questionnaire (PHQ): a diagnostic meta-analysis. J Gen Intern Med (2007) 5.24
Comorbidity and the use of primary care and specialist care in the elderly. Ann Fam Med (2005) 2.82
Signs and symptoms for diagnosis of serious infections in children: a prospective study in primary care. Br J Gen Pract (2007) 2.48
Ruling out coronary artery disease in primary care: development and validation of a simple prediction rule. CMAJ (2010) 2.37
Evidence based diagnostics. BMJ (2005) 2.07
Diagnosing depression in primary care using self-completed instruments: UK validation of PHQ-9 and CORE-OM. Br J Gen Pract (2007) 2.04
Extending an evidence hierarchy to include topics other than treatment: revising the Australian 'levels of evidence'. BMC Med Res Methodol (2009) 1.84
The 21st century: the age of family medicine research? Ann Fam Med (2004) 1.24
Strategies for molecular imaging dementia and neurodegenerative diseases. Neuropsychiatr Dis Treat (2008) 1.21
How does study quality affect the results of a diagnostic meta-analysis? BMC Med Res Methodol (2005) 1.20
Effects of the diabetes linked TCF7L2 polymorphism in a representative older population. BMC Med (2006) 1.15
Evidence-based laboratory medicine: is it working in practice? Clin Biochem Rev (2012) 1.15
Accuracy of symptoms and signs for coronary heart disease assessed in primary care. Br J Gen Pract (2010) 1.13
Movement control tests of the low back; evaluation of the difference between patients with low back pain and healthy controls. BMC Musculoskelet Disord (2008) 1.12
Accuracy of plasma sTREM-1 for sepsis diagnosis in systemic inflammatory patients: a systematic review and meta-analysis. Crit Care (2012) 1.12
A high angiopoietin-2/angiopoietin-1 ratio is associated with a high risk of septic shock in patients with febrile neutropenia. Crit Care (2013) 1.12
Point-of-care pathology with miniature microscopes. Anal Cell Pathol (Amst) (2011) 1.11
Psycholinguistic profiling differentiates specific language impairment from typical development and from attention-deficit/hyperactivity disorder. J Speech Lang Hear Res (2010) 1.02
Economic Evidence and Point-of-Care Testing. Clin Biochem Rev (2013) 1.02
The accuracy of presepsin (sCD14-ST) for the diagnosis of sepsis in adults: a meta-analysis. Crit Care (2015) 0.98
Advances in the diagnosis of degenerated lumbar discs and their possible clinical application. Eur Spine J (2013) 0.97
FDG-PET and other imaging modalities for the evaluation of breast cancer recurrence and metastases: a meta-analysis. J Cancer Res Clin Oncol (2010) 0.95
Update on clinical trials in Dysphagia. Dysphagia (2006) 0.93
Taking a new biomarker into routine use--a perspective from the routine clinical biochemistry laboratory. Proteomics Clin Appl (2010) 0.93
Sensitivity and specificity of urinary ethyl glucuronide and ethyl sulfate in liver disease patients. Alcohol Clin Exp Res (2012) 0.93
Neuroimaging tools to rate regional atrophy, subcortical cerebrovascular disease, and regional cerebral blood flow and metabolism: consensus paper of the EADC. J Neurol Neurosurg Psychiatry (2003) 0.93
User needs elicitation via analytic hierarchy process (AHP). A case study on a Computed Tomography (CT) scanner. BMC Med Inform Decis Mak (2013) 0.92
Interpreting the results of the amplified Mycobacterium tuberculosis direct test for detection of M. tuberculosis rRNA. J Clin Microbiol (2003) 0.91
How to apply the results of a research paper on diagnosis to your patient. JRSM Short Rep (2013) 0.91
Imbalances in serum angiopoietin concentrations are early predictors of septic shock development in patients with post chemotherapy febrile neutropenia. BMC Infect Dis (2010) 0.90
Effectiveness and costs of phototest in dementia and cognitive impairment screening. BMC Neurol (2011) 0.90
Clinical use of biomarkers of survival in pulmonary fibrosis. Respir Res (2010) 0.89
Role of ultrasonography in diagnosing early rheumatoid arthritis and remission of rheumatoid arthritis--a systematic review of the literature. Arthritis Res Ther (2013) 0.88
Time-course of sFlt-1 and VEGF-A release in neutropenic patients with sepsis and septic shock: a prospective study. J Transl Med (2011) 0.88
Multimodal MRI as a diagnostic biomarker for amyotrophic lateral sclerosis. Ann Clin Transl Neurol (2014) 0.88
Key concepts and limitations of statistical methods for evaluating biomarkers of kidney disease. J Am Soc Nephrol (2014) 0.88
Screening for suicide ideation among older primary care patients. J Am Board Fam Med (2010) 0.87
Noninvasive diagnostic method for idiopathic portal hypertension based on measurements of liver and spleen stiffness by ARFI elastography. J Gastroenterol (2012) 0.87
Neuroimaging as a New Diagnostic Modality in Amyotrophic Lateral Sclerosis. Neurotherapeutics (2015) 0.83
Utility of the mini-cog for detection of cognitive impairment in primary care: data from two spanish studies. Int J Alzheimers Dis (2013) 0.83
Instruments to assess patient-reported safety, efficacy, or misuse of current opioid therapy for chronic pain: a systematic review. Pain (2013) 0.82
Diagnostic accuracy, effectiveness and cost for cognitive impairment and dementia screening of three short cognitive tests applicable to illiterates. PLoS One (2011) 0.82
A cross-etiology comparison of the socio-emotional behavioral profiles associated with attention-deficit/hyperactivity disorder and specific language impairment. Clin Linguist Phon (2014) 0.82
Phonological working memory in Spanish-English bilingual children with and without specific language impairment. J Commun Disord (2007) 0.82
The Alberta Heart Failure Etiology and Analysis Research Team (HEART) study. BMC Cardiovasc Disord (2014) 0.82
Validation of new biomarkers in systemic autoimmune diseases. Nat Rev Rheumatol (2011) 0.81
Methodological deficits in diagnostic research using '-omics' technologies: evaluation of the QUADOMICS tool and quality of recently published studies. PLoS One (2010) 0.81
Validation of pharyngeal findings on sleep nasopharyngoscopy in children with snoring/sleep disordered breathing. J Otolaryngol Head Neck Surg (2014) 0.80
Diagnostic accuracy of the Eurotest for dementia: a naturalistic, multicenter phase II study. BMC Neurol (2006) 0.80
Future classification of psychotic disorders. Eur Arch Psychiatry Clin Neurosci (2009) 0.80
Association of the immature platelet fraction with sepsis diagnosis and severity. Sci Rep (2015) 0.80
Elevated [11C]-D-deprenyl uptake in chronic Whiplash Associated Disorder suggests persistent musculoskeletal inflammation. PLoS One (2011) 0.80
The true treatment benefit is unpredictable in clinical trials using surrogate outcome measured with diagnostic tests. J Clin Epidemiol (2005) 0.80
Statistical learning techniques applied to epidemiology: a simulated case-control comparison study with logistic regression. BMC Bioinformatics (2011) 0.80
Signs and symptoms that differentiate acute sinusitis from viral upper respiratory tract infection. Pediatr Infect Dis J (2013) 0.80
The functional anaesthetic discogram: description of a novel diagnostic technique and report of 3 cases. SAS J (2008) 0.79
About time: diagnostic guidelines that help clinicians. Qual Saf Health Care (2003) 0.79
A composite likelihood method for bivariate meta-analysis in diagnostic systematic reviews. Stat Methods Med Res (2014) 0.79
Performance Assessment of Four Chimeric Trypanosoma cruzi Antigens Based on Antigen-Antibody Detection for Diagnosis of Chronic Chagas Disease. PLoS One (2016) 0.79
Validating a scoring system for the diagnosis of smear-negative pulmonary tuberculosis in HIV-infected adults. PLoS One (2014) 0.78
Estimating diagnostic test accuracies for Brachyspira hyodysenteriae accounting for the complexities of population structure in food animals. PLoS One (2014) 0.78
Latent-class methods to evaluate diagnostics tests for Echinococcus infections in dogs. PLoS Negl Trop Dis (2013) 0.78
Risk prediction models for colorectal cancer in people with symptoms: a systematic review. BMC Gastroenterol (2016) 0.78
Bringing science to the art of diagnosis. Gut (2004) 0.78
Cost and utility in the diagnostic evaluation of stroke. Continuum (Minneap Minn) (2014) 0.78
Comparison of Medical Subject Headings and standard terminology regarding performance of diagnostic tests. J Med Libr Assoc (2006) 0.78
Protocol for determining the diagnostic validity of physical examination maneuvers for shoulder pathology. BMC Musculoskelet Disord (2013) 0.77
Arm Squeeze Test: a new clinical test to distinguish neck from shoulder pain. Eur Spine J (2013) 0.77
Natriuretic peptide vs. clinical information for diagnosis of left ventricular systolic dysfunction in primary care. BMC Fam Pract (2008) 0.77
The role of ultrasonography in patients with celiac disease. World J Gastroenterol (2006) 0.77
Facilitating the Validation of Novel Protein Biomarkers for Dementia: An Optimal Workflow for the Development of Sandwich Immunoassays. Front Neurol (2015) 0.76
Study of child language development and disorders in Iran: A systematic review of the literature. J Res Med Sci (2015) 0.76
Fraction of exhaled nitric oxide (FeNO ) norms in healthy Tunisian adults. Biomed Res Int (2014) 0.76
A systematic review on diagnostic procedures for specific language impairment: The sensitivity and specificity issues. J Res Med Sci (2016) 0.75
Circulating Phospholipids as Biomarkers of Breast Cancer: A Review. Breast Cancer (Auckl) (2016) 0.75
Screening high-risk patients and assisting in diagnosing anxiety in primary care: the Patient Health Questionnaire evaluated. BMC Psychiatry (2013) 0.75
Deciding on Interferon-Free Treatment for Chronic Hepatitis C: Updating Liver Stiffness Cut-Off Values to Maximize Benefit. PLoS One (2016) 0.75
Spinal Fusion for Chronic Low Back Pain: A 'Magic Bullet' or Wishful Thinking? Malays Orthop J (2016) 0.75
Development and external validation of a faecal immunochemical test-based prediction model for colorectal cancer detection in symptomatic patients. BMC Med (2016) 0.75
Does drug-induced sleep endoscopy change the surgical decision in surgically naïve non-syndromic children with snoring/sleep disordered breathing from the standard adenotonsillectomy? A retrospective cohort study. J Otolaryngol Head Neck Surg (2017) 0.75
Assessment of pain during labor with pupillometry: a prospective observational study. Anesth Analg (2013) 0.75
Methodical and pre-analytical characteristics of a multiplex cancer biomarker immunoassay. World J Methodol (2014) 0.75
Early PREdiction of Severe Sepsis (ExPRES-Sepsis) study: protocol for an observational derivation study to discover potential leucocyte cell surface biomarkers. BMJ Open (2016) 0.75
Adrenal function: A gold standard test for adrenal insufficiency in children? Nat Rev Endocrinol (2010) 0.75
Measuring brain natriuretic peptide in suspected left ventricular systolic dysfunction in general practice: cross-sectional study. BMJ (2000) 3.09
A simple clinical model for the diagnosis of deep-vein thrombosis combined with impedance plethysmography: potential for an improvement in the diagnostic process. J Intern Med (1998) 1.76
Influence of hypertension, left ventricular hypertrophy, and left ventricular systolic dysfunction on plasma N terminal proBNP. Heart (2000) 1.67
Can heart failure be diagnosed in primary care? BMJ (2000) 1.61
Cardiac natriuretic peptides for diagnosis and risk stratification in heart failure: influences of left ventricular dysfunction and coronary artery disease on cardiac hormonal activation. Eur J Clin Invest (1998) 1.60
Evidence based medicine: what it is and what it isn't. BMJ (1996) 66.70
Changing physician performance. A systematic review of the effect of continuing medical education strategies. JAMA (1995) 26.76
No magic bullets: a systematic review of 102 trials of interventions to improve professional practice. CMAJ (1995) 22.08
Evidence for the effectiveness of CME. A review of 50 randomized controlled trials. JAMA (1992) 20.08
Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med (1991) 18.33
Effects of computer-based clinical decision support systems on physician performance and patient outcomes: a systematic review. JAMA (1998) 18.02
Effects of computer-based clinical decision support systems on clinician performance and patient outcome. A critical appraisal of research. Ann Intern Med (1994) 17.27
A controlled trial of teaching critical appraisal of the clinical literature to medical students. JAMA (1987) 14.20
A performance and failure analysis of SAPHIRE with a MEDLINE test collection. J Am Med Inform Assoc (1995) 13.03
Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators. N Engl J Med (1998) 11.27
Systematic reviews: synthesis of best evidence for clinical decisions. Ann Intern Med (1997) 9.94
Increased absenteeism from work after detection and labeling of hypertensive patients. N Engl J Med (1978) 9.29
Effect of problem-based, self-directed undergraduate education on life-long learning. CMAJ (1993) 7.73
How to keep up with the medical literature: V. Access by personal computer to the medical literature. Ann Intern Med (1986) 7.36
Educational outreach visits: effects on professional practice and health care outcomes. Cochrane Database Syst Rev (2007) 7.25
Randomised clinical trial of strategies for improving medication compliance in primary hypertension. Lancet (1975) 7.22
More informative abstracts of articles describing clinical practice guidelines. Ann Intern Med (1993) 6.54
Report of the Canadian Hypertension Society Consensus Conference: 1. Introduction. CMAJ (1993) 6.20
How good are clinical MEDLINE searches? A comparative study of clinical end-user and librarian searches. Comput Biomed Res (1990) 5.95
Problems in the handling of clinical and research evidence by medical practitioners. Arch Intern Med (1983) 5.16
A critical appraisal of the efficacy of continuing medical education. JAMA (1984) 4.95
Improvement of medication compliance in uncontrolled hypertension. Lancet (1976) 4.84
Searching MEDLINE for randomized clinical trials involving care of the newborn. Pediatrics (1989) 4.79
Recommendations from the Canadian Hypertension Society Consensus Conference on the Pharmacologic Treatment of Hypertension. CMAJ (1989) 4.76
Evaluation of SAPHIRE: an automated approach to indexing and retrieving medical literature. Proc Annu Symp Comput Appl Med Care (1991) 4.59
Practitioners of evidence based care. Not all clinicians need to appraise evidence from scratch but all need some skills. BMJ (2000) 4.41
Enhancing retrieval of best evidence for health care from bibliographic databases: calibration of the hand search of the literature. Stud Health Technol Inform (2001) 4.08
Clinical decision support systems for the practice of evidence-based medicine. J Am Med Inform Assoc (2001) 3.90
A taxonomy and critical review of tested strategies for the application of clinical practice recommendations: from "official" to "individual" clinical policy. Am J Prev Med (1988) 3.77
Designing medical informatics research and library--resource projects to increase what is learned. J Am Med Inform Assoc (1995) 3.74
The Internet and evidence-based decision-making: a needed synergy for efficient knowledge management in health care. CMAJ (2000) 3.46
Computer searching of the medical literature. An evaluation of MEDLINE searching systems. Ann Intern Med (1985) 3.45
The North American Symptomatic Carotid Endarterectomy Trial : surgical results in 1415 patients. Stroke (1999) 3.31
Can simple clinical measurements detect patient noncompliance? Hypertension (1981) 3.29
Planning for the information age: a survey of microcomputer use in a faculty of health sciences. CMAJ (1987) 3.24
Does a mailed continuing education program improve physician performance? Results of a randomized trial in antihypertensive care. JAMA (1986) 3.04
Educational outreach visits: effects on professional practice and health care outcomes. Cochrane Database Syst Rev (2000) 3.04
The measurement iterative loop: a framework for the critical appraisal of need, benefits and costs of health interventions. J Chronic Dis (1985) 2.96
How to keep up with the medical literature: I. Why try to keep up and how to get started. Ann Intern Med (1986) 2.94
Computer-aided quality assurance. A critical appraisal. Arch Intern Med (1987) 2.69
A candidate gene approach to searching for low-penetrance breast and prostate cancer genes. Nat Rev Cancer (2005) 2.62
How was your hospital stay? Patients' reports about their care in Canadian hospitals. CMAJ (1994) 2.48
Recommendations from the Canadian Hypertension Society Consensus Conference on Hypertension and Diabetes. CMAJ (1988) 2.36
Local opinion leaders: effects on professional practice and health care outcomes. Cochrane Database Syst Rev (2000) 2.33
A framework for clinical evaluation of diagnostic technologies. CMAJ (1986) 2.26
The rational clinical examination. Is this patient taking the treatment as prescribed? JAMA (1993) 2.23
Assessment of methodologic search filters in MEDLINE. Proc Annu Symp Comput Appl Med Care (1993) 2.19
An overview of interventions to improve compliance with appointment keeping for medical services. JAMA (1992) 2.13
Problems encountered by clinical end users of MEDLINE and GRATEFUL MED. Bull Med Libr Assoc (1991) 2.10
Transferring evidence from research into practice: 1. The role of clinical care research evidence in clinical decisions. ACP J Club (1996) 2.10
Grateful Med. MD Comput (1987) 2.09
Of studies, syntheses, synopses, and systems: the "4S" evolution of services for finding current best evidence. ACP J Club (2001) 2.00
Patient compliance and the conduct and interpretation of therapeutic trials. Control Clin Trials (1987) 1.86
Audit and feedback versus alternative strategies: effects on professional practice and health care outcomes. Cochrane Database Syst Rev (2000) 1.79
Labelling in hypertension: a review of the behavioural and psychological consequences. J Chronic Dis (1984) 1.75
How to keep up with the medical literature: IV. Using the literature to solve clinical problems. Ann Intern Med (1986) 1.75
Educational package on hypertension for primary care physicians. Can Med Assoc J (1984) 1.73
A randomized trial of improved weight loss with a prepared meal plan in overweight and obese patients: impact on cardiovascular risk reduction. Arch Intern Med (2000) 1.58
How to keep up with the medical literature: II. Deciding which journals to read regularly. Ann Intern Med (1986) 1.57
Dietary compliance and cardiovascular risk reduction with a prepared meal plan compared with a self-selected diet. Am J Clin Nutr (1997) 1.57
Work-site treatment of hypertension by specially trained nurses. A controlled trial. Lancet (1979) 1.53
Audit and feedback: effects on professional practice and health care outcomes. Cochrane Database Syst Rev (2000) 1.53
Guidelines for the clinical and economic evaluation of health care technologies. Soc Sci Med (1986) 1.47
Patient compliance with antihypertensive regimens. Patient Couns Health Educ (1978) 1.31
PREOP: development of an evidence-based expert system to assist with preoperative assessments. Proc Annu Symp Comput Appl Med Care (1991) 1.30
Manipulation of the therapeutic regimen to improve compliance: conceptions and misconceptions. Clin Pharmacol Ther (1977) 1.25
Predicting compliance with a regimen of digoxin therapy in family practice. Can Med Assoc J (1980) 1.24
The Cochrane Collaboration--advances and challenges in improving evidence-based decision making. Med Decis Making (1998) 1.23
Compliance with antihypertensive drug therapy. Ann N Y Acad Sci (1978) 1.23
New approaches to addressing information needs in local public health agencies. Can J Public Health (1991) 1.22
Association between renal insufficiency and malnutrition in older adults: results from the NHANES III. Kidney Int (2001) 1.20
Carotid endarterectomy for symptomatic carotid stenosis. Cochrane Database Syst Rev (2000) 1.19
Lost in publication: Half of all renal practice evidence is published in non-renal journals. Kidney Int (2006) 1.19
The role of before-after studies of therapeutic impact in the evaluation of diagnostic technologies. J Chronic Dis (1986) 1.15
A critical appraisal of the literature on the effects of computer-based clinical decision support systems on clinician performance and patient outcomes. Proc Annu Symp Comput Appl Med Care (1992) 1.14
How to keep up with the medical literature: III. Expanding the number of journals you read regularly. Ann Intern Med (1986) 1.14
Effects of labelling on income, work and social function among hypertensive employees. J Chronic Dis (1984) 1.13
Functional status changes following medical or surgical treatment for cerebral ischemia. Results of the extracranial-intracranial bypass study. JAMA (1987) 1.12
Multicenter randomized trial of a comprehensive prepared meal program in type 2 diabetes. Diabetes Care (1999) 1.12
Cost-effectiveness of a worksite hypertension treatment program. Hypertension (1981) 1.08
A critical review of compliance studies in rheumatoid arthritis. Arthritis Rheum (1984) 1.07
Transferring evidence from research into practice: 4. Overcoming barriers to application. ACP J Club (1997) 1.07
Failure of weight reduction to reduce mildly elevated blood pressure: a randomized trial. J Hypertens (1984) 1.07
Process versus outcome in hypertension: a positive result. Circulation (1982) 1.06
Teaching clinicians to search MEDLINE: description and evaluation of a short course. Res Med Educ (1986) 1.05
Transferring evidence from research into practice: 2. Getting the evidence straight. ACP J Club (1997) 1.05
How to keep up with the medical literature: VI. How to store and retrieve articles worth keeping. Ann Intern Med (1986) 1.03
Can bruits distinguish high-grade from moderate symptomatic carotid stenosis? The North American Symptomatic Carotid Endarterectomy Trial. Ann Intern Med (1994) 1.03
Can computerized clinical decision support systems improve diabetes management? A systematic review and meta-analysis. Diabet Med (2013) 1.03
Automated direct-from-patient information collection for evidence-based diabetes care. Proc AMIA Annu Fall Symp (1997) 1.01
Clinical expertise in the era of evidence-based medicine and patient choice. Vox Sang (2002) 1.00
How to detect and manage low patient compliance in chronic illness. Geriatrics (1980) 0.99
Clinical review articles. BMJ (1992) 0.98
Clinical effectiveness and cost-effectiveness of monitoring blood pressure of hypertensive employees at work. Hypertension (1984) 0.98