Published in Early Hum Dev on March 01, 1979
Early exposure to anesthesia and learning disabilities in a population-based birth cohort. Anesthesiology (2009) 9.51
Isoflurane-induced neuroapoptosis in the neonatal rhesus macaque brain. Anesthesiology (2010) 4.44
Antiepileptic drugs and apoptotic neurodegeneration in the developing brain. Proc Natl Acad Sci U S A (2002) 4.18
Role for Akt3/protein kinase Bgamma in attainment of normal brain size. Mol Cell Biol (2005) 4.00
The dynamic effects of nicotine on the developing brain. Pharmacol Ther (2009) 3.01
Extrapolating brain development from experimental species to humans. Neurotoxicology (2007) 2.73
Potential of ketamine and midazolam, individually or in combination, to induce apoptotic neurodegeneration in the infant mouse brain. Br J Pharmacol (2005) 2.61
Rats exposed to isoflurane in utero during early gestation are behaviorally abnormal as adults. Anesthesiology (2011) 2.41
Competing interactions between micro-RNAs determine neural progenitor survival and proliferation after ethanol exposure: evidence from an ex vivo model of the fetal cerebral cortical neuroepithelium. J Neurosci (2007) 2.30
Fetal programming of hypothalamo-pituitary-adrenal function: prenatal stress and glucocorticoids. J Physiol (2006) 2.18
Stressed-out, or in (utero)? Trends Neurosci (2002) 2.08
Persistent neurochemical and behavioral abnormalities in adulthood despite early iron supplementation for perinatal iron deficiency anemia in rats. Behav Brain Res (2006) 2.02
Human prenatal and postnatal exposure to polybrominated diphenyl ethers, polychlorinated biphenyls, polychlorobiphenylols, and pentachlorophenol. Environ Health Perspect (2003) 2.00
Impact of anaesthetics and surgery on neurodevelopment: an update. Br J Anaesth (2013) 1.99
Selective anesthesia-induced neuroinflammation in developing mouse brain and cognitive impairment. Anesthesiology (2013) 1.93
Early-life programming of later-life brain and behavior: a critical role for the immune system. Front Behav Neurosci (2009) 1.89
Transgenerational impact of intimate partner violence on methylation in the promoter of the glucocorticoid receptor. Transl Psychiatry (2011) 1.85
Low-level human equivalent gestational lead exposure produces sex-specific motor and coordination abnormalities and late-onset obesity in year-old mice. Environ Health Perspect (2008) 1.84
Comparative developmental neurotoxicity of organophosphates in vivo: transcriptional responses of pathways for brain cell development, cell signaling, cytotoxicity and neurotransmitter systems. Brain Res Bull (2007) 1.72
Clinical anesthesia causes permanent damage to the fetal guinea pig brain. Brain Pathol (2008) 1.71
Isoflurane-induced apoptosis of oligodendrocytes in the neonatal primate brain. Ann Neurol (2012) 1.70
Brain development in rodents and humans: Identifying benchmarks of maturation and vulnerability to injury across species. Prog Neurobiol (2013) 1.69
Ketamine-induced neuroapoptosis in the fetal and neonatal rhesus macaque brain. Anesthesiology (2012) 1.59
Isoflurane preconditioning improves short-term and long-term neurological outcome after focal brain ischemia in adult rats. Neuroscience (2009) 1.50
Neuronal cell death in neonatal hypoxia-ischemia. Ann Neurol (2011) 1.47
Neurotoxicity of brominated flame retardants: (in)direct effects of parent and hydroxylated polybrominated diphenyl ethers on the (developing) nervous system. Environ Health Perspect (2011) 1.47
High dose magnesium sulfate exposure induces apoptotic cell death in the developing neonatal mouse brain. Neonatology (2009) 1.46
The role of GABAA receptors in mediating the effects of alcohol in the central nervous system. J Psychiatry Neurosci (2003) 1.44
Maternal transfer of the cyanobacterial neurotoxin β-N-methylamino-L-alanine (BMAA) via milk to suckling offspring. PLoS One (2013) 1.43
The role of iron in learning and memory. Adv Nutr (2011) 1.43
Long-lasting alterations to DNA methylation and ncRNAs could underlie the effects of fetal alcohol exposure in mice. Dis Model Mech (2013) 1.42
Long-term alterations of striatal parvalbumin interneurons in a rat model of early exposure to alcohol. J Neurodev Disord (2012) 1.42
Neonatal exposure to antiepileptic drugs disrupts striatal synaptic development. Ann Neurol (2012) 1.39
Timing versus duration: determinants of anesthesia-induced developmental apoptosis in the young mammalian brain. Ann N Y Acad Sci (2010) 1.37
Limited effects of preterm birth and the first enteral nutrition on cerebellum morphology and gene expression in piglets. Physiol Rep (2016) 1.37
Lithium protects against anesthesia-induced developmental neuroapoptosis. Anesthesiology (2009) 1.33
Exposure to organophosphates reduces the expression of neurotrophic factors in neonatal rat brain regions: similarities and differences in the effects of chlorpyrifos and diazinon on the fibroblast growth factor superfamily. Environ Health Perspect (2007) 1.32
Effects of fetal exposure to isoflurane on postnatal memory and learning in rats. Neuropharmacology (2007) 1.31
Prenatal choline supplementation mitigates the adverse effects of prenatal alcohol exposure on development in rats. Neurotoxicol Teratol (2009) 1.30
The effects of prenatal alcohol exposure on behavior: rodent and primate studies. Neuropsychol Rev (2011) 1.27
Choline supplementation attenuates learning deficits associated with neonatal alcohol exposure in the rat: effects of varying the timing of choline administration. Brain Res (2008) 1.27
Comparison of the maturation of the adrenergic and serotonergic neurotransmitter systems in the brain: implications for differential drug effects on juveniles and adults. Biochem Pharmacol (2007) 1.27
Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar. Br J Anaesth (2013) 1.26
Short periods of prenatal stress affect growth, behaviour and hypothalamo-pituitary-adrenal axis activity in male guinea pig offspring. J Physiol (2005) 1.26
Nicotine-induced plasticity during development: modulation of the cholinergic system and long-term consequences for circuits involved in attention and sensory processing. Neuropharmacology (2008) 1.26
Isoflurane-induced apoptosis of neurons and oligodendrocytes in the fetal rhesus macaque brain. Anesthesiology (2014) 1.26
Centella asiatica (L.) leaf extract treatment during the growth spurt period enhances hippocampal CA3 neuronal dendritic arborization in rats. Evid Based Complement Alternat Med (2006) 1.25
Ethanol causes and lithium prevents neuroapoptosis and suppression of pERK in the infant mouse brain. Neurobiol Dis (2008) 1.24
Experimental model of pediatric asphyxial cardiopulmonary arrest in rats. Pediatr Crit Care Med (2004) 1.24
Growth impairment in the very preterm and cognitive and motor performance at 7 years. Arch Dis Child (2003) 1.21
Dimethyl sulfoxide (DMSO) produces widespread apoptosis in the developing central nervous system. Neurobiol Dis (2008) 1.20
Prenatal choline supplementation mitigates behavioral alterations associated with prenatal alcohol exposure in rats. Birth Defects Res A Clin Mol Teratol (2010) 1.17
Rapid NMDA receptor phosphorylation and oxidative stress precede striatal neurodegeneration after hypoxic ischemia in newborn piglets and are attenuated with hypothermia. Int J Dev Neurosci (2007) 1.14
Effects of neonatal antiepileptic drug exposure on cognitive, emotional, and motor function in adult rats. J Pharmacol Exp Ther (2011) 1.14
Alcohol-induced neuroapoptosis in the fetal macaque brain. Neurobiol Dis (2010) 1.13
Brain growth of the domestic pig (Sus scrofa) from 2 to 24 weeks of age: a longitudinal MRI study. Dev Neurosci (2012) 1.11
Transgenerational effects of prenatal nutrient restriction on cardiovascular and hypothalamic-pituitary-adrenal function. J Physiol (2008) 1.08
Multiple Anesthetic Exposure in Infant Monkeys Alters Emotional Reactivity to an Acute Stressor. Anesthesiology (2015) 1.08
Neurodevelopmental alcohol exposure elicits long-term changes to gene expression that alter distinct molecular pathways dependent on timing of exposure. J Neurodev Disord (2013) 1.08
Fetal learning about ethanol and later ethanol responsiveness: evidence against "safe" amounts of prenatal exposure. Exp Biol Med (Maywood) (2008) 1.07
Anesthesia-induced neurodegeneration in fetal rat brains. Pediatr Res (2009) 1.07
Mild traumatic brain injury to the infant mouse causes robust white matter axonal degeneration which precedes apoptotic death of cortical and thalamic neurons. Exp Neurol (2008) 1.07
Prenatal glucocorticoid exposure alters hypothalamic-pituitary-adrenal function and blood pressure in mature male guinea pigs. J Physiol (2004) 1.05
Cortico-thalamic connectivity is vulnerable to nicotine exposure during early postnatal development through α4/β2/α5 nicotinic acetylcholine receptors. Neuropsychopharmacology (2010) 1.04
Neonatal exposure to phenobarbital potentiates schizophrenia-like behavioral outcomes in the rat. Neuropharmacology (2012) 1.04
Ketamine enhances human neural stem cell proliferation and induces neuronal apoptosis via reactive oxygen species-mediated mitochondrial pathway. Anesth Analg (2013) 1.03
Systemic stimulation of TLR2 impairs neonatal mouse brain development. PLoS One (2011) 1.02
Diet-induced iron deficiency anemia and pregnancy outcome in rhesus monkeys. Am J Clin Nutr (2006) 1.02
Critical role for glial cells in the propagation and spread of lymphocytic choriomeningitis virus in the developing rat brain. J Virol (2002) 1.02
Is neuronal death required for seizure-induced epileptogenesis in the immature brain? Prog Brain Res (2002) 1.02
The International society for developmental psychobiology 39th annual meeting symposium: Alcohol and development: beyond fetal alcohol syndrome. Dev Psychobiol (2007) 1.01
Environmental agents that have the potential to trigger massive apoptotic neurodegeneration in the developing brain. Environ Health Perspect (2000) 1.01
Placental adaptations in growth restriction. Nutrients (2015) 1.01
In utero domoic acid toxicity: a fetal basis to adult disease in the California sea lion (Zalophus californianus). Mar Drugs (2008) 1.01
Administration of eliprodil during ethanol withdrawal in the neonatal rat attenuates ethanol-induced learning deficits. Psychopharmacology (Berl) (2004) 1.00
Resveratrol restores Nrf2 level and prevents ethanol-induced toxic effects in the cerebellum of a rodent model of fetal alcohol spectrum disorders. Mol Pharmacol (2011) 0.99
Voluntary exercise influences behavioral development in rats exposed to alcohol during the neonatal brain growth spurt. Behav Neurosci (2008) 0.99
Behavior and monoamine deficits in prenatal and perinatal iron deficiency are not corrected by early postnatal moderate-iron or high-iron diets in rats. J Nutr (2012) 0.99
Neurodevelopment at 1 year of age in infants with congenital heart disease. Heart (2003) 0.98
Choline supplementation and DNA methylation in the hippocampus and prefrontal cortex of rats exposed to alcohol during development. Alcohol Clin Exp Res (2012) 0.98
17beta-estradiol protects against hypoxic/ischemic white matter damage in the neonatal rat brain. J Neurosci Res (2009) 0.98
Long-term effects of neonatal single or multiple isoflurane exposures on spatial memory in rats. Front Neurol (2013) 0.98
Childhood and adolescent depression: why do children and adults respond differently to antidepressant drugs? Neurochem Int (2007) 0.97
Pattern of antiepileptic drug-induced cell death in limbic regions of the neonatal rat brain. Epilepsia (2011) 0.97
A comparison of the different animal models of fetal alcohol spectrum disorders and their use in studying complex behaviors. Front Pediatr (2014) 0.97
Scaled cortical impact in immature swine: effect of age and gender on lesion volume. J Neurotrauma (2009) 0.96
Variants of contextual fear conditioning are differentially impaired in the juvenile rat by binge ethanol exposure on postnatal days 4-9. Behav Brain Res (2010) 0.96
The effects of exercise on adolescent hippocampal neurogenesis in a rat model of binge alcohol exposure during the brain growth spurt. Brain Res (2009) 0.96
Developmental changes in the expression of creatine synthesizing enzymes and creatine transporter in a precocial rodent, the spiny mouse. BMC Dev Biol (2009) 0.96
General anesthetics in pediatric anesthesia: influences on the developing brain. Curr Drug Targets (2012) 0.96
GABAA receptors, anesthetics and anticonvulsants in brain development. CNS Neurol Disord Drug Targets (2008) 0.95
Effect of antenatal betamethasone treatment on microtubule-associated proteins MAP1B and MAP2 in fetal sheep. J Physiol (2001) 0.95
Place and direction learning in a spatial T-maze task by neonatal piglets. Anim Cogn (2012) 0.95
Mechanisms of ethanol-induced death of cerebellar granule cells. Cerebellum (2012) 0.95
Toxicity of the flame-retardant BDE-49 on brain mitochondria and neuronal progenitor striatal cells enhanced by a PTEN-deficient background. Toxicol Sci (2013) 0.94
Bacterial infection early in life protects against stressor-induced depressive-like symptoms in adult rats. Psychoneuroendocrinology (2008) 0.94
Embryonic exposure to domoic Acid increases the susceptibility of zebrafish larvae to the chemical convulsant pentylenetetrazole. Environ Health Perspect (2007) 0.94
An in vivo three-dimensional magnetic resonance imaging-based averaged brain collection of the neonatal piglet (Sus scrofa). PLoS One (2014) 0.94
Epileptogenesis in the developing brain: what can we learn from animal models? Epilepsia (2007) 0.94
Anesthesia-induced developmental neurodegeneration: the role of neuronal organelles. Front Neurol (2012) 0.94
Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena. Cell (1982) 12.12
Quantitative growth and development of human brain. Arch Dis Child (1973) 6.19
The influence of the spleen in carbon monoxide poisoning. J Physiol (1925) 5.90
A new cluster of genes within the human major histocompatibility complex. Science (1989) 2.76
T-cell lymphomas containing Epstein-Barr viral DNA in patients with chronic Epstein-Barr virus infections. N Engl J Med (1988) 2.63
Undernutrition and the developing brain. The relevance of animal models to the human problem. Am J Dis Child (1970) 2.09
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Vulnerability of developing brain. IX. The effect of nutritional growth retardation on the timing of the brain growth-spurt. Biol Neonate (1971) 1.70
Vulnerability of developing brain. VII. Permanent deficit of neurons in cerebral and cerebellar cortex following early mild undernutrition. Exp Neurol (1971) 1.65
Growth and development of the brain and spinal cord of the guinea pig. Brain Res (1970) 1.64
A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and a single ubiquitin-like domain. Proc Natl Acad Sci U S A (1990) 1.59
Head circumference, biparietal diameter and brain growth in fetal and postnatal life. Early Hum Dev (1978) 1.56
Timing of neuroblast multiplication in developing human brain. Nature (1970) 1.52
Extreme sensitivity of enveloped viruses, including herpes simplex, to long-chain unsaturated monoglycerides and alcohols. Antimicrob Agents Chemother (1979) 1.47
Vulnerability of developing brain and behaviour. Br Med Bull (1974) 1.46
European versus U.S. data on the course of schizophrenia. Am J Psychiatry (1991) 1.39
Health workers and the baby food industry. Subject deserves much more serious consideration. BMJ (1996) 1.37
Effect of lipid alkyl chain perturbations on the assembly of bacteriophage PM2. Biochim Biophys Acta (1975) 1.37
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Inactivation of the enveloped bacteriophage phi6 by butylated hydroxytoluene and butylated hydroxyanisole. Antimicrob Agents Chemother (1976) 1.27
Fetal damage despite low-phenylalanine diet after conception in a phenylketonuric woman. Lancet (1979) 1.21
Synapse-to-neuron ratios of the frontal and cerebellar cortex of 30-day-old and adult rats undernourished during early postnatal life. J Comp Neurol (1980) 1.15
A stereological analysis of the cerebellar granule and Purkinje cells of 30-day-old and adult rats undernourished during early postnatal life. J Comp Neurol (1980) 1.11
Vulnerability of developing brain: relative effects of growth restriction during the fetal and suckling periods on behavior and brain composition of adult rats. J Nutr (1973) 1.09
Prenatal and postnatal growth and development of the central nervous system of the pig. Proc R Soc Lond B Biol Sci (1967) 1.07
How to organise an international medical meeting. Br Med J (1978) 1.03
The effect of undernutrition and subsequent rehabilitation on myelination of rat brain as measured by its composition. Brain (1965) 1.02
Neuroleptic depression in schizophrenia. Biol Psychiatry (1991) 0.99
Cerebral edema in developing brain. I. Normal water and cation content in developing rat brain and postmortem changes. Exp Neurol (1971) 0.97
Deciduous teeth contain histories of developmental disturbances. Early Hum Dev (1979) 0.97
Vulnerability of developing brain. 8. Regional acetylcholinesterase activity in the brains of adult rats undernourished in early life. Br J Nutr (1972) 0.96
The development of the blood-brain barrier. Prog Brain Res (1968) 0.95
Motor co-ordination and cerebellar size in adult rats undernourished in early life. Brain Res (1975) 0.95
Vulnerable periods of brain development. In: lipids, malnutrition & the developing brain. Ciba Found Symp (1971) 0.94
Modulation of HLA class II antigen expression by transfection of sense and antisense DR alpha cDNA. J Exp Med (1989) 0.94
Infant nutrition and later achievement. Nutr Rev (1984) 0.93
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A stereological analysis of the neuronal and synaptic content of the frontal and cerebellar cortex of weanling rats undernourished from birth. Early Hum Dev (1979) 0.91
Undernutrition in early life: lasting effects on activity and social behavior of male and female rats. Dev Psychobiol (1976) 0.91
Elevated acetylcholinesterase activity in adult rat brain after undernutrition in early life. Brain Res (1971) 0.91
The human obesity gene map: the 2000 update. Obes Res (2001) 0.91
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Control of phospholipid synthesis and viral assembly by bacteriophage PM2. Biochim Biophys Acta (1974) 0.90
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Deficits in synapse-to-neuron ratio due to early undernutrition show evidence of catch-up in later life. Experientia (1980) 0.88
A prospective longitudinal 10-year study of schizophrenia's three major factors and depression. Psychiatry Res (2000) 0.87
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Vulnerability of developing brain not explained by cell number/cell size hypothesis. Early Hum Dev (1981) 0.82
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Increased thirst and hunger in adult rats undernourished as infants: an alternative explanation. Br J Nutr (1977) 0.80
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An alternative animal model for the full-term small-for-dates human baby. Biol Neonate (1973) 0.78
Cell size and cell number: a reconsideration of organ growth and catch-up potential. Proc Nutr Soc (1979) 0.78
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A comparison of the effects of cytosine arabinoside and adenine arabinoside on some aspects of brain growth and development in the rat. Br J Pharmacol (1975) 0.75
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Mechanism of virucidal activity of retinoids: protein removal from bacteriophage phi 6 envelope. Antimicrob Agents Chemother (1980) 0.75