Published in Neurology on March 12, 2002
Human embryonic stem cell-derived GABA neurons correct locomotion deficits in quinolinic acid-lesioned mice. Cell Stem Cell (2012) 2.62
Unilateral transplantation of human primary fetal tissue in four patients with Huntington's disease: NEST-UK safety report ISRCTN no 36485475. J Neurol Neurosurg Psychiatry (2002) 1.76
Fetal striatal grafting slows motor and cognitive decline of Huntington's disease. J Neurol Neurosurg Psychiatry (2013) 1.55
A patient with Huntington's disease and long-surviving fetal neural transplants that developed mass lesions. Acta Neuropathol (2008) 1.25
We need something better, and we need it now: fetal striatal transplantation in Huntington's disease? Neurology (2002) 1.10
Symptomatic treatment of Huntington disease. Neurotherapeutics (2008) 1.08
Functional imaging in Huntington's disease. Exp Neurol (2009) 1.08
Human mesenchymal stem cells prolong survival and ameliorate motor deficit through trophic support in Huntington's disease mouse models. PLoS One (2011) 1.02
Chorea and related disorders. Postgrad Med J (2004) 0.99
Cellular therapy and induced neuronal replacement for Huntington's disease. Neurotherapeutics (2011) 0.97
The long-term safety and efficacy of bilateral transplantation of human fetal striatal tissue in patients with mild to moderate Huntington's disease. J Neurol Neurosurg Psychiatry (2013) 0.96
Cell therapy in Huntington's disease. NeuroRx (2004) 0.94
The paradigm of Huntington's disease: therapeutic opportunities in neurodegeneration. NeuroRx (2004) 0.91
The Dark Side of the Force - Constraints and Complications of Cell Therapies for Stroke. Front Neurol (2015) 0.89
Devices for cell transplantation into the central nervous system: Design considerations and emerging technologies. Surg Neurol Int (2013) 0.89
The Current Status of Neural Grafting in the Treatment of Huntington's Disease. A Review. Front Integr Neurosci (2011) 0.87
Restoration of the striatal circuitry: from developmental aspects toward clinical applications. Front Cell Neurosci (2012) 0.83
Molecular regulation of striatal development: a review. Anat Res Int (2012) 0.82
Human pluripotent stem cell therapy for Huntington's disease: technical, immunological, and safety challenges human pluripotent stem cell therapy for Huntington's disease: technical, immunological, and safety challenges. Neurotherapeutics (2011) 0.81
Radially branched deployment for more efficient cell transplantation at the scale of the human brain. Stereotact Funct Neurosurg (2013) 0.81
Organization of the human fetal subpallium. Front Neuroanat (2014) 0.80
Bilateral human fetal striatal transplantation in Huntington's disease. Neurology (2002) 0.79
Positron emission tomography imaging of transplant function. NeuroRx (2004) 0.78
The design of clinical trials for cell transplantation into the central nervous system. NeuroRx (2004) 0.77
PET Imaging in Huntington's Disease. J Huntingtons Dis (2015) 0.75
Stem Cell Therapy for the Central Nervous System in Lysosomal Storage Diseases. Hum Gene Ther (2016) 0.75
A greedy algorithm for aligning DNA sequences. J Comput Biol (2000) 47.89
Strength-duration curves for repetitive stimulation of medullated nerve. J Physiol (1934) 15.94
Comparative analyses of multi-species sequences from targeted genomic regions. Nature (2003) 13.31
Integration of cytogenetic landmarks into the draft sequence of the human genome. Nature (2001) 10.96
Growth of factor-dependent hemopoietic precursor cell lines. J Exp Med (1980) 5.80
arrow encodes an LDL-receptor-related protein essential for Wingless signalling. Nature (2000) 5.13
Socioeconomic status and psychiatric disorders: the causation-selection issue. Science (1992) 4.95
A new human prostate carcinoma cell line, 22Rv1. In Vitro Cell Dev Biol Anim (1999) 4.93
Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats. Stroke (2001) 4.64
Adult bone marrow stromal cells differentiate into neural cells in vitro. Exp Neurol (2000) 4.56
Double-blind study of botulinum toxin in spasmodic torticollis. Lancet (1986) 4.54
A dust-obscured massive maximum-starburst galaxy at a redshift of 6.34. Nature (2013) 4.43
Redesigning an FKBP-ligand interface to generate chemical dimerizers with novel specificity. Proc Natl Acad Sci U S A (1998) 3.88
The prevalence of rheumatoid arthritis in the United Kingdom: new estimates for a new century. Rheumatology (Oxford) (2002) 3.87
Comparative sequence analysis of a gene-rich cluster at human chromosome 12p13 and its syntenic region in mouse chromosome 6. Genome Res (1998) 3.80
Inherited microdeletions in the Angelman and Prader-Willi syndromes define an imprinting centre on human chromosome 15. Nat Genet (1995) 3.79
A humanized system for pharmacologic control of gene expression. Nat Med (1996) 3.69
Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease. N Engl J Med (1995) 3.64
The action of gamma-aminobutyric acid on cortical neurones. Exp Brain Res (1967) 3.45
Structure of chromosomal duplicons and their role in mediating human genomic disorders. Genome Res (2000) 3.30
AA2500 testosterone gel normalizes androgen levels in aging males with improvements in body composition and sexual function. J Clin Endocrinol Metab (2003) 3.19
Expectation and dopamine release: mechanism of the placebo effect in Parkinson's disease. Science (2001) 3.18
The role of radiotracer imaging in Parkinson disease. Neurology (2005) 3.02
Declining HIV/AIDS mortality in New York City. J Acquir Immune Defic Syndr (1999) 3.01
Comparative analysis of the gene-dense ACHE/TFR2 region on human chromosome 7q22 with the orthologous region on mouse chromosome 5. Nucleic Acids Res (2001) 2.89
Heatstroke in well-wrapped infants. Lancet (1979) 2.81
WWOX: a candidate tumor suppressor gene involved in multiple tumor types. Proc Natl Acad Sci U S A (2001) 2.79
Functional neuroanatomical correlates of hysterical sensorimotor loss. Brain (2001) 2.75
BRAF screening as a low-cost effective strategy for simplifying HNPCC genetic testing. J Med Genet (2004) 2.75
Chromosome breakage in the Prader-Willi and Angelman syndromes involves recombination between large, transcribed repeats at proximal and distal breakpoints. Am J Hum Genet (1999) 2.71
Regulation of protein secretion through controlled aggregation in the endoplasmic reticulum. Science (2000) 2.70
Beyond the language barrier. Nature (1997) 2.70
Neuroleptic dysphoria. Biol Psychiatry (1991) 2.66
CACP, encoding a secreted proteoglycan, is mutated in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Nat Genet (1999) 2.60
Pain reduction in local anesthetic administration through pH buffering. Ann Emerg Med (1988) 2.59
Mutations in the novel protocadherin PCDH15 cause Usher syndrome type 1F. Hum Mol Genet (2001) 2.48
Group A beta-hemolytic streptococci resistant to erythromycin and lincomycin. N Engl J Med (1968) 2.44
Effect of food supplementation during pregnancy on birthweight. Pediatrics (1975) 2.39
The changing purpose of Prader-Willi syndrome clinical diagnostic criteria and proposed revised criteria. Pediatrics (2001) 2.37
Globin gene server: a prototype E-mail database server featuring extensive multiple alignments and data compilation for electronic genetic analysis. Genomics (1994) 2.36
Biochemical variations in the synaptic level of dopamine precede motor fluctuations in Parkinson's disease: PET evidence of increased dopamine turnover. Ann Neurol (2001) 2.31
Emotional facial expressions capture attention. Neurology (2001) 2.25
Canagliflozin improves glycaemic control over 28 days in subjects with type 2 diabetes not optimally controlled on insulin. Diabetes Obes Metab (2012) 2.19
Evaluation of mental retardation: recommendations of a Consensus Conference: American College of Medical Genetics. Am J Med Genet (1997) 2.19
CWR22: the first human prostate cancer xenograft with strongly androgen-dependent and relapsed strains both in vivo and in soft agar. Cancer Res (1996) 2.18
Methane-oxidizing microorganisms. Microbiol Rev (1981) 2.17
Methylprednisolone and cyclophosphamide, alone or in combination, in patients with lupus nephritis. A randomized, controlled trial. Ann Intern Med (1996) 2.17
Image-guided transorbital roof craniotomy via a suprabrow approach: a surgical series of 72 patients. Neurosurgery (2001) 2.13
Modification and validation of the Birmingham Vasculitis Activity Score (version 3). Ann Rheum Dis (2008) 2.12
The effect of severe caries on the quality of life in young children. Pediatr Dent (1999) 2.10
How should different life expectancies be valued? BMJ (1998) 2.10
KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression. Oncogene (2006) 2.07
Nicotine potentiation of haloperidol in reducing tic frequency in Tourette's disorder. Am J Psychiatry (1991) 2.04
A versatile synthetic dimerizer for the regulation of protein-protein interactions. Proc Natl Acad Sci U S A (1997) 2.04
Identification of centromeric antigens in dicentric Robertsonian translocations: CENP-C and CENP-E are necessary components of functional centromeres. Hum Mol Genet (1995) 2.04
BSR and BHPR guidelines for the management of adults with ANCA associated vasculitis. Rheumatology (Oxford) (2007) 2.02
Nicotinic acetylcholine receptors as targets for antidepressants. Mol Psychiatry (2002) 2.02
Outcomes from studies of antineutrophil cytoplasm antibody associated vasculitis: a systematic review by the European League Against Rheumatism systemic vasculitis task force. Ann Rheum Dis (2007) 2.01
QALYs for resource allocation: a reply to Burrows and Brown. Aust J Public Health (1993) 1.97
The mosaic structure of human pericentromeric DNA: a strategy for characterizing complex regions of the human genome. Genome Res (2000) 1.97
An analysis of lamellar x-ray diffraction from disordered membrane multilayers with application to data from retinal rod outer segments. Biophys J (1975) 1.97
Macular full-thickness and lamellar holes in association with type 2 idiopathic macular telangiectasia. Eye (Lond) (2008) 1.96
Endomysial antibody: is it the best screening test for coeliac disease? Gut (1992) 1.93
Transplantation of cryopreserved human embryonal carcinoma-derived neurons (NT2N cells) promotes functional recovery in ischemic rats. Exp Neurol (1998) 1.89
Pervasive occult gastrointestinal bleeding in an Alaska native population with prevalent iron deficiency. Role of Helicobacter pylori gastritis. JAMA (1997) 1.89
Prevalence of antigliadin antibodies in ataxia patients. Neurology (2003) 1.89
Elevated body swing test: a new behavioral parameter for rats with 6-hydroxydopamine-induced hemiparkinsonism. J Neurosci (1995) 1.88
Translational inhibition in vitro of human papillomavirus type 16 L2 mRNA mediated through interaction with heterogenous ribonucleoprotein K and poly(rC)-binding proteins 1 and 2. J Biol Chem (1998) 1.88
Difficult extubation due to transfixation of a nasotracheal tube by a Kirschner wire. Anesthesiology (1977) 1.88
A novel human immunodeficiency virus type 1 protein, tev, shares sequences with tat, env, and rev proteins. J Virol (1990) 1.87
Genetic heterogeneity in familial idiopathic basal ganglia calcification (Fahr disease). Neurology (2004) 1.87
BAC microarray analysis of 15q11-q13 rearrangements and the impact of segmental duplications. J Med Genet (2004) 1.87
Autosomal dominant parkinsonism associated with variable synuclein and tau pathology. Neurology (2004) 1.86
Transmission of a balanced homologous t(22q;22q) translocation from mother to normal daughter. Clin Genet (1980) 1.84
Body size at birth and blood pressure among children in developing countries. Int J Epidemiol (2001) 1.83
Isolation and characterisation of a bipotential haematopoietic cell line. Nature (1979) 1.80
The insulin-sensitizing agent troglitazone improves metabolic and reproductive abnormalities in the polycystic ovary syndrome. J Clin Endocrinol Metab (1996) 1.80
Intravenous versus intrastriatal cord blood administration in a rodent model of stroke. J Neurosci Res (2003) 1.79
Relation of serum total cholesterol and high-density lipoprotein cholesterol percentage to the incidence of definite coronary events: twenty-year follow-up of the Donolo-Tel Aviv Prospective Coronary Artery Disease Study. Am J Cardiol (1987) 1.78
CWR22: androgen-dependent xenograft model derived from a primary human prostatic carcinoma. Cancer Res (1994) 1.77
A truncated cardiac troponin T molecule in transgenic mice suggests multiple cellular mechanisms for familial hypertrophic cardiomyopathy. J Clin Invest (1998) 1.77
Collagen XVIII, containing an endogenous inhibitor of angiogenesis and tumor growth, plays a critical role in the maintenance of retinal structure and in neural tube closure (Knobloch syndrome). Hum Mol Genet (2000) 1.76
Analysis of mecamylamine stereoisomers on human nicotinic receptor subtypes. J Pharmacol Exp Ther (2001) 1.74
Early Permian bipedal reptile. Science (2000) 1.73
Pten (phosphatase and tensin homologue gene) haploinsufficiency promotes insulin hypersensitivity. Diabetologia (2006) 1.72
International consensus outcome measures for patients with idiopathic inflammatory myopathies. Development and initial validation of myositis activity and damage indices in patients with adult onset disease. Rheumatology (Oxford) (2003) 1.71
Public knowledge, attitudes, and beliefs about homeless people: evidence for compassion fatigue. Am J Community Psychol (1995) 1.69
Role of fibreoptic bronchoscopy in management of pneumonia in acquired immune deficiency syndrome. Br Med J (Clin Res Ed) (1985) 1.68
Decentralizing a community mental health center's service delivery system. Hosp Community Psychiatry (1974) 1.68
Two functional states of the CD11b A-domain: correlations with key features of two Mn2+-complexed crystal structures. J Cell Biol (1998) 1.67
Cell death, chromosome damage and mitotic delay in normal human, ataxia telangiectasia and retinoblastoma fibroblasts after x-irradiation. Int J Radiat Biol Relat Stud Phys Chem Med (1981) 1.66
In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease. Ann Neurol (2000) 1.65