Published in Regul Pept on May 15, 2002
From the genome to the proteome: uncovering peptides in the Apis brain. Science (2006) 2.25
Identification and validation of housekeeping genes in brains of the desert locust Schistocerca gregaria under different developmental conditions. BMC Mol Biol (2009) 1.84
Human white blood cells synthesize morphine: CYP2D6 modulation. J Immunol (2005) 1.72
Defective processing of neuropeptide precursors in Caenorhabditis elegans lacking proprotein convertase 2 (KPC-2/EGL-3): mutant analysis by mass spectrometry. J Neurochem (2006) 1.42
A two-state model of antagonist-AT1 receptor interaction: further support by binding studies at low temperature. Biochem Pharmacol (2003) 1.40
Impaired processing of FLP and NLP peptides in carboxypeptidase E (EGL-21)-deficient Caenorhabditis elegans as analyzed by mass spectrometry. J Neurochem (2007) 1.35
The role of octopamine in locusts and other arthropods. J Insect Physiol (2010) 1.20
Characterization of an orphan G protein-coupled receptor localized in the dorsal root ganglia reveals adenine as a signaling molecule. Proc Natl Acad Sci U S A (2002) 1.18
Discovering neuropeptides in Caenorhabditis elegans by two dimensional liquid chromatography and mass spectrometry. Biochem Biophys Res Commun (2005) 1.16
Elusive equilibrium: the challenge of interpreting receptor pharmacology using calcium assays. Br J Pharmacol (2010) 1.13
Combining in silico prediction and ribosome profiling in a genome-wide search for novel putatively coding sORFs. BMC Genomics (2013) 1.12
Neuropeptidomic analysis of the brain and thoracic ganglion from the Jonah crab, Cancer borealis. Biochem Biophys Res Commun (2003) 1.10
A study of the molecular mechanism of binding kinetics and long residence times of human CCR5 receptor small molecule allosteric ligands. Br J Pharmacol (2014) 1.09
Peptidomics: the integrated approach of MS, hyphenated techniques and bioinformatics for neuropeptide analysis. J Sep Sci (2008) 1.03
A proteomic approach for the analysis of instantly released wound and immune proteins in Drosophila melanogaster hemolymph. Proc Natl Acad Sci U S A (2004) 1.00
The construction of a bioactive peptide database in Metazoa. J Proteome Res (2008) 0.98
Identification in Drosophila melanogaster of the invertebrate G protein-coupled FMRFamide receptor. Proc Natl Acad Sci U S A (2002) 0.96
Molecular mechanisms of corticotropin-releasing factor receptor-induced calcium signaling. Mol Pharmacol (2008) 0.95
Proteomics in Drosophila melanogaster: first 2D database of larval hemolymph proteins. Biochem Biophys Res Commun (2003) 0.95
Agonist induction and conformational selection during activation of a G-protein-coupled receptor. Trends Pharmacol Sci (2003) 0.94
Peptidomics coming of age: a review of contributions from a bioinformatics angle. J Proteome Res (2010) 0.93
In silico identification of new secretory peptide genes in Drosophila melanogaster. Mol Cell Proteomics (2005) 0.93
Structural and functional properties of a novel serine protease inhibiting peptide family in arthropods. Comp Biochem Physiol B Biochem Mol Biol (2002) 0.93
Neurokinin 1 receptor antagonists: correlation between in vitro receptor interaction and in vivo efficacy. J Pharmacol Exp Ther (2007) 0.93
Expression of a novel neuropeptide, NVGTLARDFQLPIPNamide, in the larval and adult brain of Drosophila melanogaster. J Neurochem (2004) 0.93
Evaluation of normalization methods to pave the way towards large-scale LC-MS-based metabolomics profiling experiments. OMICS (2013) 0.91
Uncovering conserved patterns in bioactive peptides in Metazoa. Peptides (2006) 0.91
SIFamide is a highly conserved neuropeptide: a comparative study in different insect species. Biochem Biophys Res Commun (2004) 0.90
Synthesis and characterization of potent and selective mu-opioid receptor antagonists, [Dmt(1), D-2-Nal(4)]endomorphin-1 (Antanal-1) and [Dmt(1), D-2-Nal(4)]endomorphin-2 (Antanal-2). J Med Chem (2007) 0.90
Neuropeptides of the islets of Langerhans: a peptidomics study. Gen Comp Endocrinol (2007) 0.90
Peptidomics in Drosophila melanogaster. Brief Funct Genomic Proteomic (2003) 0.90
Identification of new immune induced molecules in the haemolymph of Drosophila melanogaster by 2D-nanoLC MS/MS. J Insect Physiol (2006) 0.89
Neuropeptidomics of the grey flesh fly, Neobellieria bullata. Biochem Biophys Res Commun (2004) 0.88
Angiotensin IV is a potent agonist for constitutive active human AT1 receptors. Distinct roles of the N-and C-terminal residues of angiotensin II during AT1 receptor activation. J Biol Chem (2002) 0.87
Direct profiling and identification of peptide expression differences in the pancreas of control and ob/ob mice by imaging mass spectrometry. Proteomics (2008) 0.87
Involvement of insulin-regulated aminopeptidase in the effects of the renin-angiotensin fragment angiotensin IV: a review. Heart Fail Rev (2007) 0.86
Isolation and functional characterization of an allatotropin receptor from Manduca sexta. Insect Biochem Mol Biol (2011) 0.85
The hemolymph proteome of the honeybee: gel-based or gel-free? Proteomics (2009) 0.85
Comparative peptidomics of Caenorhabditis elegans versus C. briggsae by LC-MALDI-TOF MS. Peptides (2008) 0.85
Pressor and renal hemodynamic effects of the novel angiotensin A peptide are angiotensin II type 1A receptor dependent. Hypertension (2011) 0.85
In vitro inhibition of [3H]-angiotensin II binding on the human AT1 receptor by proanthocyanidins from Guazuma ulmifolia bark. Planta Med (2002) 0.85
Bioinformatic approaches to the identification of novel neuropeptide precursors. Methods Mol Biol (2010) 0.84
Genomics, evolution and biological functions of the pacifastin peptide family: a conserved serine protease inhibitor family in arthropods. Peptides (2003) 0.84
Characterization of an allatotropin-like peptide receptor in the red flour beetle, Tribolium castaneum. Insect Biochem Mol Biol (2011) 0.84
Novel highly potent mu-opioid receptor antagonist based on endomorphin-2 structure. Bioorg Med Chem Lett (2008) 0.84
Disulfide cyclized tripeptide analogues of angiotensin IV as potent and selective inhibitors of insulin-regulated aminopeptidase (IRAP). J Med Chem (2010) 0.84
Endogenous cystinyl aminopeptidase in Chinese hamster ovary cells: characterization by [125I]Ang IV binding and catalytic activity. Biochem Pharmacol (2004) 0.83
KLHL12-mediated ubiquitination of the dopamine D4 receptor does not target the receptor for degradation. Cell Signal (2010) 0.83
Antagonist-radioligand binding to D2L-receptors in intact cells. Biochem Pharmacol (2008) 0.82
Proteomic analysis of formalin-fixed paraffin-embedded colorectal cancer tissue using tandem mass tag protein labeling. Mol Biosyst (2013) 0.81
Expression, binding, and signaling properties of CRF2(a) receptors endogenously expressed in human retinoblastoma Y79 cells: passage-dependent regulation of functional receptors. J Neurochem (2007) 0.81
Synergistic modulation of cystinyl aminopeptidase by divalent cation chelators. Biochem Pharmacol (2004) 0.81
Identification, distribution and molecular evolution of the pacifastin gene family in Metazoa. BMC Evol Biol (2009) 0.80
Peptide and nonpeptide antagonist interaction with constitutively active human AT1 receptors. Biochem Pharmacol (2003) 0.80
Inhibitory activity on binding of specific ligands to the human angiotensin II AT(1) and endothelin 1 ET(A) receptors: bioactive benzo[c]phenanthridine alkaloids from the root of Bocconia frutescens. Planta Med (2002) 0.80
Ligand binding and functional properties of human angiotensin AT1 receptors in transiently and stably expressed CHO-K1 cells. Eur J Pharmacol (2005) 0.79
Ligands to the (IRAP)/AT4 receptor encompassing a 4-hydroxydiphenylmethane scaffold replacing Tyr2. Bioorg Med Chem (2008) 0.79
A hybrid, de novo based, genome-wide database search approach applied to the sea urchin neuropeptidome. J Proteome Res (2010) 0.79
Effect of saponin and filipin on antagonist binding to AT 1 receptors in intact cells. Biochem Pharmacol (2004) 0.79
Characterization of four substrates emphasizes kinetic similarity between insect and human C-domain angiotensin-converting enzyme. Eur J Biochem (2002) 0.79
Improving the identification rate of endogenous peptides using electron transfer dissociation and collision-induced dissociation. J Proteome Res (2013) 0.79
Isolation and characterization of an angiotensin converting enzyme substrate from vitellogenic ovaries of Neobellieria bullata. Peptides (2002) 0.79
Involvement of the AT1 receptor subtype in the effects of angiotensin IV and LVV-haemorphin 7 on hippocampal neurotransmitter levels and spatial working memory. J Neurochem (2009) 0.79
Angiotensin AT4 receptor ligand interaction with cystinyl aminopeptidase and aminopeptidase N: [125I]Angiotensin IV only binds to the cystinyl aminopeptidase apo-enzyme. Eur J Pharmacol (2006) 0.79
Identification of tryptophan and beta-carboline as paralysins in larvae of the yellow mealworm, Tenebrio molitor. Biochem Biophys Res Commun (2003) 0.79
Neuropeptide biology in Drosophila. Adv Exp Med Biol (2010) 0.78
Gel-based proteomics approach to the study of metabolic changes in pear tissue during storage. J Agric Food Chem (2009) 0.78
Comparison of extraction methods for peptidomics analysis of mouse brain tissue. J Neurosci Methods (2011) 0.78
B chromosomes showing active ribosomal RNA genes contribute insignificant amounts of rRNA in the grasshopper Eyprepocnemis plorans. Mol Genet Genomics (2014) 0.78
The replacement of His(4) in angiotensin IV by conformationally constrained residues provides highly potent and selective analogues. J Med Chem (2009) 0.78
Synergistic inhibition of the enzymatic activity of aminopeptidase N by divalent metal ion chelators. Fundam Clin Pharmacol (2006) 0.78
Binding properties of antagonists to cannabinoid receptors in intact cells. Fundam Clin Pharmacol (2011) 0.78
Cyclic insulin-regulated aminopeptidase (IRAP)/AT4 receptor ligands. J Pept Sci (2006) 0.78
Unravelling the complex dissociation of [(3)H]-rimonabant from plated CB(1) cannabinoid receptor-expressing cells. Fundam Clin Pharmacol (2009) 0.78
Metabolism of angiotensin II is required for its in vivo effect on dopamine release in the striatum of the rat. J Neurochem (2004) 0.78
Cold stress alters Mytilus edulis pedal ganglia expression of mu opiate receptor transcripts determined by real-time RT-PCR and morphine levels. Brain Res Mol Brain Res (2002) 0.78
Molecular mechanism of allosteric modulation at GPCRs: insight from a binding kinetics study at the human A1 adenosine receptor. Br J Pharmacol (2014) 0.77
Antagonist-D2S-dopamine receptor interactions in intact recombinant Chinese hamster ovary cells [corrected]. Fundam Clin Pharmacol (2009) 0.77
Frog nuptial pads secrete mating season-specific proteins related to salamander pheromones. J Exp Biol (2013) 0.77
Growth-inhibition effects of pacifastin-like peptides on a pest insect: the desert locust, Schistocerca gregaria. Peptides (2011) 0.77
Beta-homo-amino acid scan of angiotensin IV. J Med Chem (2008) 0.77
Involvement of insulin-regulated aminopeptidase and/or aminopeptidase N in the angiotensin IV-induced effect on dopamine release in the striatum of the rat. Brain Res (2006) 0.77
Isolation and identification of the AKH III precursor-related peptide from Locusta migratoria. Biochem Biophys Res Commun (2002) 0.77
Peptidomic analysis of human reflex tear fluid. Peptides (2012) 0.77
Potent macrocyclic inhibitors of insulin-regulated aminopeptidase (IRAP) by olefin ring-closing metathesis. J Med Chem (2011) 0.77
MALDI MS imaging as a tool for biomarker discovery: methodological challenges in a clinical setting. Proteomics Clin Appl (2012) 0.77
Distinct binding properties of the AT(1) receptor antagonist [(3)H]candesartan to intact cells and membrane preparations. Biochem Pharmacol (2002) 0.77
Metal ion modulation of cystinyl aminopeptidase. Biochem J (2005) 0.77
Amino triazolo diazepines (Ata) as constrained histidine mimics. Org Lett (2011) 0.76
Substitution of conserved glycine residue by alanine in natural and synthetic neuropeptide ligands causes partial agonism at the stomoxytachykinin receptor. J Neurochem (2004) 0.76