Published in J Cell Biochem on January 01, 2002
Possible involvement of pregnane X receptor-enhanced CYP24 expression in drug-induced osteomalacia. J Clin Invest (2005) 1.96
The peripheral benzodiazepine receptor ligand 1-(2-chlorophenyl-methylpropyl)-3-isoquinoline-carboxamide is a novel antagonist of human constitutive androstane receptor. Mol Pharmacol (2008) 1.38
Evolution and function of the NR1I nuclear hormone receptor subfamily (VDR, PXR, and CAR) with respect to metabolism of xenobiotics and endogenous compounds. Curr Drug Metab (2006) 1.32
Activation of the steroid and xenobiotic receptor, SXR, induces apoptosis in breast cancer cells. BMC Cancer (2009) 1.02
Endocrine disrupting contaminants--beyond the dogma. Environ Health Perspect (2006) 1.00
The role of the nuclear receptor constitutive androstane receptor in the pathogenesis of non-alcoholic steatohepatitis. Gut (2006) 0.98
Orphan nuclear receptors as targets for drug development. Pharm Res (2010) 0.97
Activation of xenobiotic receptors: driving into the nucleus. Expert Opin Drug Metab Toxicol (2010) 0.92
Rational quantitative structure-activity relationship (RQSAR) screen for PXR and CAR isoform-specific nuclear receptor ligands. Chem Biol Interact (2010) 0.90
PPARγ and NF-κB regulate the gene promoter activity of their shared repressor, TNIP1. Biochim Biophys Acta (2011) 0.84
Preferential physical and functional interaction of pregnane X receptor with the SMRTalpha isoform. Mol Pharmacol (2008) 0.81
Molecular dynamics simulations of the human CAR ligand-binding domain: deciphering the molecular basis for constitutive activity. J Mol Model (2004) 0.79
Effect of rifampin on production of inflammatory mediators in HepG2 liver epithelial cells. Antimicrob Agents Chemother (2011) 0.79
Small-molecule modulators of the constitutive androstane receptor. Expert Opin Drug Metab Toxicol (2015) 0.77
High glucose decreases expression and activity of p-glycoprotein in cultured human retinal pigment epithelium possibly through iNOS induction. PLoS One (2012) 0.77
Targeting the pregnane X receptor in liver injury. Expert Opin Ther Targets (2012) 0.76
Quantitative High-Throughput Luciferase Screening in Identifying CAR Modulators. Methods Mol Biol (2016) 0.75
Retracted Population-level transcription cycles derive from stochastic timing of single-cell transcription. Cell (2009) 2.09
Regulation of the human p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 receptor. Nucleic Acids Res (2006) 1.89
Comprehensive analysis of PPARalpha-dependent regulation of hepatic lipid metabolism by expression profiling. PPAR Res (2007) 1.88
Regulation of the expression of inducible nitric oxide synthase. Nitric Oxide (2010) 1.82
Green tea inhibits human inducible nitric-oxide synthase expression by down-regulating signal transducer and activator of transcription-1alpha activation. Mol Pharmacol (2004) 1.74
Involvement of KSRP in the post-transcriptional regulation of human iNOS expression-complex interplay of KSRP with TTP and HuR. Nucleic Acids Res (2005) 1.69
Spatio-temporal activation of chromatin on the human CYP24 gene promoter in the presence of 1alpha,25-Dihydroxyvitamin D3. J Mol Biol (2005) 1.64
Chronic therapy with isosorbide-5-mononitrate causes endothelial dysfunction, oxidative stress, and a marked increase in vascular endothelin-1 expression. Eur Heart J (2012) 1.47
The interleukin-22/STAT3 pathway potentiates expression of inducible nitric-oxide synthase in human colon carcinoma cells. J Biol Chem (2007) 1.42
The human peroxisome proliferator-activated receptor delta gene is a primary target of 1alpha,25-dihydroxyvitamin D3 and its nuclear receptor. J Mol Biol (2005) 1.39
Nuclear hormone 1α,25-dihydroxyvitamin D3 elicits a genome-wide shift in the locations of VDR chromatin occupancy. Nucleic Acids Res (2011) 1.38
Nitric oxide increases the decay of matrix metalloproteinase 9 mRNA by inhibiting the expression of mRNA-stabilizing factor HuR. Mol Cell Biol (2003) 1.35
Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism. J Biol Chem (2011) 1.34
Profiling of promoter occupancy by PPARalpha in human hepatoma cells via ChIP-chip analysis. Nucleic Acids Res (2010) 1.34
The polypyrimidine tract-binding protein (PTB) is involved in the post-transcriptional regulation of human inducible nitric oxide synthase expression. J Biol Chem (2006) 1.32
Cyclical chromatin looping and transcription factor association on the regulatory regions of the p21 (CDKN1A) gene in response to 1alpha,25-dihydroxyvitamin D3. J Biol Chem (2009) 1.28
Interferon-gamma induces chronic active myocarditis and cardiomyopathy in transgenic mice. Am J Pathol (2007) 1.26
Tristetraprolin regulates the expression of the human inducible nitric-oxide synthase gene. Mol Pharmacol (2005) 1.25
Meta-analysis of primary target genes of peroxisome proliferator-activated receptors. Genome Biol (2007) 1.20
Regulation of the human cyclin C gene via multiple vitamin D3-responsive regions in its promoter. Nucleic Acids Res (2005) 1.18
The insulin-like growth factor-binding protein 1 gene is a primary target of peroxisome proliferator-activated receptors. J Biol Chem (2006) 1.18
Three members of the human pyruvate dehydrogenase kinase gene family are direct targets of the peroxisome proliferator-activated receptor beta/delta. J Mol Biol (2007) 1.16
Glyceraldehyde-3-phosphate dehydrogenase regulates endothelin-1 expression by a novel, redox-sensitive mechanism involving mRNA stability. Mol Cell Biol (2008) 1.15
Selective use of multiple vitamin D response elements underlies the 1 alpha,25-dihydroxyvitamin D3-mediated negative regulation of the human CYP27B1 gene. Nucleic Acids Res (2007) 1.14
25-Hydroxyvitamin D(3) is an agonistic vitamin D receptor ligand. J Steroid Biochem Mol Biol (2009) 1.12
Lovastatin inhibits Rho-regulated expression of E-selectin by TNFalpha and attenuates tumor cell adhesion. FASEB J (2003) 1.11
Human red blood cells at work: identification and visualization of erythrocytic eNOS activity in health and disease. Blood (2012) 1.11
The human hyaluronan synthase 2 gene is a primary retinoic acid and epidermal growth factor responding gene. J Biol Chem (2005) 1.10
Regulation of multiple insulin-like growth factor binding protein genes by 1alpha,25-dihydroxyvitamin D3. Nucleic Acids Res (2005) 1.10
Distinct HDACs regulate the transcriptional response of human cyclin-dependent kinase inhibitor genes to Trichostatin A and 1alpha,25-dihydroxyvitamin D3. Nucleic Acids Res (2007) 1.09
ALDH-2 deficiency increases cardiovascular oxidative stress--evidence for indirect antioxidative properties. Biochem Biophys Res Commun (2007) 1.09
Vascular dysfunction in experimental diabetes is improved by pentaerithrityl tetranitrate but not isosorbide-5-mononitrate therapy. Diabetes (2011) 1.07
Functional characterization of vitamin D responding regions in the human 5-Lipoxygenase gene. Biochim Biophys Acta (2007) 1.06
Role of copper, zinc, selenium and tellurium in the cellular defense against oxidative and nitrosative stress. J Nutr (2003) 1.05
A role of melatonin in neuroectodermal-mesodermal interactions: the hair follicle synthesizes melatonin and expresses functional melatonin receptors. FASEB J (2005) 1.03
Epigenetic control of a VDR-governed feed-forward loop that regulates p21(waf1/cip1) expression and function in non-malignant prostate cells. Nucleic Acids Res (2010) 1.03
Regulation of the hyaluronan synthase 2 gene by convergence in cyclic AMP response element-binding protein and retinoid acid receptor signaling. J Biol Chem (2009) 1.02
NO signaling confers cytoprotectivity through the survivin network in ovarian carcinomas. Cancer Res (2008) 1.02
Post-transcriptional regulation of human inducible nitric-oxide synthase expression by the Jun N-terminal kinase. Mol Pharmacol (2007) 1.02
Transcriptional and post-transcriptional regulation of iNOS expression in human chondrocytes. Biochem Pharmacol (2009) 1.00
Structural determinants of the agonist-independent association of human peroxisome proliferator-activated receptors with coactivators. J Biol Chem (2005) 1.00
Genome-wide landscape of liver X receptor chromatin binding and gene regulation in human macrophages. BMC Genomics (2012) 1.00
Rho protein-mediated changes in the structure of the actin cytoskeleton regulate human inducible NO synthase gene expression. Exp Cell Res (2003) 1.00
Inhibition of cytokine secretion from adipocytes by 1,25-dihydroxyvitamin D₃ via the NF-κB pathway. FASEB J (2012) 0.99
Primary effect of 1α,25(OH)₂D₃ on IL-10 expression in monocytes is short-term down-regulation. Biochim Biophys Acta (2010) 0.98
Modulation of mouse and human phenobarbital-responsive enhancer module by nuclear receptors. Mol Pharmacol (2002) 0.98
Cellular content of UDP-N-acetylhexosamines controls hyaluronan synthase 2 expression and correlates with O-linked N-acetylglucosamine modification of transcription factors YY1 and SP1. J Biol Chem (2011) 0.97
Dataset integration identifies transcriptional regulation of microRNA genes by PPARγ in differentiating mouse 3T3-L1 adipocytes. Nucleic Acids Res (2012) 0.97
1,25-dihydroxyvitamin D3 influences cellular homocysteine levels in murine preosteoblastic MC3T3-E1 cells by direct regulation of cystathionine β-synthase. J Bone Miner Res (2011) 0.97
Differential effects of 1α,25-dihydroxycholecalciferol on MCP-1 and adiponectin production in human white adipocytes. Eur J Nutr (2011) 0.95
Epigenetic corruption of VDR signalling in malignancy. Anticancer Res (2006) 0.95
Integration of the activation of the human hyaluronan synthase 2 gene promoter by common cofactors of the transcription factors retinoic acid receptor and nuclear factor kappaB. J Biol Chem (2007) 0.95
Singlet oxygen-induced signaling effects in mammalian cells. Photochem Photobiol Sci (2003) 0.95
Anti-inflammatory actions of St. John's wort: inhibition of human inducible nitric-oxide synthase expression by down-regulating signal transducer and activator of transcription-1alpha (STAT-1alpha) activation. J Pharmacol Exp Ther (2003) 0.94
Differential haplotypic expression of the interleukin-18 gene. Eur J Hum Genet (2007) 0.94
Vitamin D receptor agonists specifically modulate the volume of the ligand-binding pocket. J Biol Chem (2006) 0.93
New aspects of adipogenesis: radicals and oxidative stress. Differentiation (2008) 0.93
Antiatherosclerotic effects of small-molecular-weight compounds enhancing endothelial nitric-oxide synthase (eNOS) expression and preventing eNOS uncoupling. J Pharmacol Exp Ther (2008) 0.92
The down-regulation of the human MYC gene by the nuclear hormone 1alpha,25-dihydroxyvitamin D3 is associated with cycling of corepressors and histone deacetylases. J Mol Biol (2010) 0.92
The number of vitamin D receptor binding sites defines the different vitamin D responsiveness of the CYP24 gene in malignant and normal mammary cells. J Biol Chem (2010) 0.91
Time-resolved expression profiling of the nuclear receptor superfamily in human adipogenesis. PLoS One (2010) 0.91
Similar regulation of human inducible nitric-oxide synthase expression by different isoforms of the RNA-binding protein AUF1. J Biol Chem (2008) 0.91
Role of SIRT1 and FOXO factors in eNOS transcriptional activation by resveratrol. Nitric Oxide (2013) 0.90
Mechanism of 1α,25-dihydroxyvitamin D(3)-dependent repression of interleukin-12B. Biochim Biophys Acta (2011) 0.90
Necrosis is the predominant type of islet cell death during development of insulin-dependent diabetes mellitus in BB rats. Lab Invest (2003) 0.90
Nitric oxide-mediated protection of endothelial cells from hydrogen peroxide is mediated by intracellular zinc and glutathione. Am J Physiol Cell Physiol (2009) 0.90
Sporogen, S14-95, and S-curvularin, three inhibitors of human inducible nitric-oxide synthase expression isolated from fungi. Mol Pharmacol (2003) 0.90
A Role for the PPARgamma in Cancer Therapy. PPAR Res (2008) 0.89
Characterization of DNA complexes formed by the nuclear receptor constitutive androstane receptor. J Biol Chem (2003) 0.89
Chromatin acetylation at transcription start sites and vitamin D receptor binding regions relates to effects of 1α,25-dihydroxyvitamin D3 and histone deacetylase inhibitors on gene expression. Nucleic Acids Res (2012) 0.89
Primary 1,25-dihydroxyvitamin D3 response of the interleukin 8 gene cluster in human monocyte- and macrophage-like cells. PLoS One (2013) 0.89
A structural basis for the species-specific antagonism of 26,23-lactones on vitamin D signaling. Chem Biol (2004) 0.89
The highly conserved region of the co-repressor Sin3A functionally interacts with the co-repressor Alien. Nucleic Acids Res (2004) 0.89
Design principles of nuclear receptor signaling: how complex networking improves signal transduction. Mol Syst Biol (2010) 0.88
Transcriptional regulation of Nox4 by histone deacetylases in human endothelial cells. Basic Res Cardiol (2012) 0.88
The anti-inflammatory fungal compound (S)-curvularin reduces proinflammatory gene expression in an in vivo model of rheumatoid arthritis. J Pharmacol Exp Ther (2012) 0.88
Identification of pregnane X receptor binding sites in the regulatory regions of genes involved in bile acid homeostasis. J Mol Biol (2005) 0.87
Mitochondrial oxidative stress and nitrate tolerance--comparison of nitroglycerin and pentaerithrityl tetranitrate in Mn-SOD+/- mice. BMC Cardiovasc Disord (2006) 0.87
Structural evaluation of the agonistic action of a vitamin D analog with two side chains binding to the nuclear vitamin D receptor. Mol Pharmacol (2003) 0.87
Regulation of cyclooxygenase-2 expression by cyclic AMP. Biochim Biophys Acta (2007) 0.87
Analysis of the 5-lipoxygenase promoter and characterization of a vitamin D receptor binding site. Biochim Biophys Acta (2006) 0.87
Nitrite, a naturally occurring precursor of nitric oxide that acts like a 'prodrug'. Biol Chem (2006) 0.87
Differential nuclear receptor signalling from DR4-type response elements. J Cell Biochem (2002) 0.87
Dynamics of 1α,25-dihydroxyvitamin D3-dependent chromatin accessibility of early vitamin D receptor target genes. Biochim Biophys Acta (2013) 0.86
The gene for the transcription factor BHLHE40/DEC1/stra13 is a dynamically regulated primary target of the vitamin D receptor. J Steroid Biochem Mol Biol (2012) 0.85
Direct evidence that (-)-epicatechin increases nitric oxide levels in human endothelial cells. Eur J Nutr (2011) 0.85
Gene regulatory potential of nonsteroidal vitamin D receptor ligands. Mol Endocrinol (2005) 0.84
Induction of tolerogenic lung CD4+ T cells by local treatment with a pSTAT-3 and pSTAT-5 inhibitor ameliorated experimental allergic asthma. Int Immunol (2010) 0.84
Cyclical regulation of the insulin-like growth factor binding protein 3 gene in response to 1alpha,25-dihydroxyvitamin D3. Nucleic Acids Res (2010) 0.84
Nitric oxide and downstream second messenger cGMP and cAMP enhance adipogenesis in primary human preadipocytes. Cytotherapy (2010) 0.84
Cross-repression, a functional consequence of the physical interaction of non-liganded nuclear receptors and POU domain transcription factors. J Biol Chem (2002) 0.83
Coordinate induction of PPAR alpha and SREBP2 in multifunctional protein 2 deficient mice. Biochim Biophys Acta (2008) 0.83
The genes of the coactivator TIF2 and the corepressor SMRT are primary 1alpha,25(OH)2D3 targets. J Steroid Biochem Mol Biol (2004) 0.83
Impact of Mycoplasma hyorhinis infection on L-arginine metabolism: differential regulation of the human and murine iNOS gene. Biol Chem (2005) 0.82
Circulating microparticles carry a functional endothelial nitric oxide synthase that is decreased in patients with endothelial dysfunction. J Am Heart Assoc (2012) 0.82
Agonist-dependent and agonist-independent transactivations of the human constitutive androstane receptor are modulated by specific amino acid pairs. J Biol Chem (2004) 0.82
Subcellular localisation of BAG-1 and its regulation of vitamin D receptor-mediated transactivation and involucrin expression in oral keratinocytes: implications for oral carcinogenesis. Exp Cell Res (2007) 0.82
Corepressor excess shifts the two-side chain vitamin D analog Gemini from an agonist to an inverse agonist of the vitamin D receptor. Mol Endocrinol (2003) 0.82
Antagonist- and inverse agonist-driven interactions of the vitamin D receptor and the constitutive androstane receptor with corepressor protein. Mol Endocrinol (2005) 0.82
Variations in the ghrelin receptor gene associate with obesity and glucose metabolism in individuals with impaired glucose tolerance. PLoS One (2008) 0.82