Published in Trends Endocrinol Metab on April 01, 2002
TRPV2 has a pivotal role in macrophage particle binding and phagocytosis. Nat Immunol (2010) 1.56
alpha-Thrombin induces rapid and sustained Akt phosphorylation by beta-arrestin1-dependent and -independent mechanisms, and only the sustained Akt phosphorylation is essential for G1 phase progression. J Biol Chem (2002) 1.30
The sphingosine and diacylglycerol kinase superfamily of signaling kinases: localization as a key to signaling function. J Lipid Res (2006) 1.10
Stimulation of the Raf/MEK/ERK cascade is necessary and sufficient for activation and Thr-160 phosphorylation of a nuclear-targeted CDK2. J Biol Chem (2002) 1.05
A new lipase in regulating lipid mobilization: hormone-sensitive lipase is not alone. Trends Endocrinol Metab (2005) 1.04
Reverse mutational analysis reveals threonine-373 as a potentially sufficient phosphorylation site for inactivation of the retinoblastoma tumor suppressor protein (pRB). Cell Cycle (2006) 1.01
Alpha-thrombin-mediated phosphatidylinositol 3-kinase activation through release of Gbetagamma dimers from Galphaq and Galphai2. J Biol Chem (2003) 0.97
Receptor type protein tyrosine phosphatase-kappa mediates cross-talk between transforming growth factor-beta and epidermal growth factor receptor signaling pathways in human keratinocytes. Mol Biol Cell (2009) 0.97
Modulation of diacylglycerol kinase theta activity by alpha-thrombin and phospholipids. Biochemistry (2007) 0.94
Regulation and roles of neuronal diacylglycerol kinases: a lipid perspective. Crit Rev Biochem Mol Biol (2011) 0.92
Expression of cyclin E renders cyclin D-CDK4 dispensable for inactivation of the retinoblastoma tumor suppressor protein, activation of E2F, and G1-S phase progression. J Biol Chem (2003) 0.92
Cyclin A-CDK activity during G1 phase impairs MCM chromatin loading and inhibits DNA synthesis in mammalian cells. Cell Cycle (2008) 0.91
Zinc induces ERK-dependent cell death through a specific Ras isoform. Apoptosis (2006) 0.90
Activation of Cdk2/Cyclin E complexes is dependent on the origin of replication licensing factor Cdc6 in mammalian cells. Cell Cycle (2010) 0.90
The extreme COOH terminus of the retinoblastoma tumor suppressor protein pRb is required for phosphorylation on Thr-373 and activation of E2F. Am J Physiol Cell Physiol (2008) 0.89
Phosphatidylinositol 3-kinase regulates macrophage responses to double-stranded RNA and encephalomyocarditis virus. J Innate Immun (2009) 0.81
Regulation of DGK-theta. J Cell Physiol (2009) 0.81
DGK and nuclear signaling nuclear diacylglycerol kinases in IIC9 cells. Adv Enzyme Regul (2002) 0.81
Dual regulation of diacylglycerol kinase (DGK)-θ: polybasic proteins promote activation by phospholipids and increase substrate affinity. J Biol Chem (2012) 0.81
Diacylglycerol kinase θ: regulation and stability. Adv Biol Regul (2012) 0.80
Characterization of cellular DGK-theta. Adv Enzyme Regul (2009) 0.80
Diacylglycerol kinases put the brakes on immune function. Sci STKE (2007) 0.80
The expression of diacylglycerol kinase theta during the organogenesis of mouse embryos. BMC Dev Biol (2013) 0.80
Analysis of two diacylglycerol kinase activities in mixed micelles. Adv Enzyme Regul (2006) 0.80
beta-Arrestin 1 couples thrombin to the rapid activation of the Akt pathway. Ann N Y Acad Sci (2002) 0.79
Killing two birds with one RKIP. Trends Endocrinol Metab (2004) 0.79
The ethanol metabolite, linolenic acid ethyl ester, stimulates mitogen-activated protein kinase and cyclin signaling in hepatic stellate cells. Life Sci (2003) 0.79
RNA interference takes flight: a new RNAi screen reveals cell cycle regulators in Drosophila cells. Trends Endocrinol Metab (2006) 0.79
Loss of H2A.Z Is Not Sufficient to Determine Transcriptional Activity of Snf2-Related CBP Activator Protein or p400 Complexes. Int J Cell Biol (2011) 0.78
Analysis of a novel diacylglycerol kinase from Dictyostelium discoideum: DGKA. Biochemistry (2005) 0.78
A novel role for Gq alpha in alpha-thrombin-mediated mitogenic signalling pathways. Cell Signal (2002) 0.78
CDK2 and cyclin E knockout mice: lessons from breast cancer. Trends Endocrinol Metab (2003) 0.78
Identification and characterization of a novel Mdm2 splice variant acutely induced by the chemotherapeutic agents adriamycin and actinomycin D. Cell Cycle (2008) 0.77
The rapid activation of N-Ras by alpha-thrombin in fibroblasts is mediated by the specific G-protein Galphai2-Gbeta1-Ggamma5 and occurs in lipid rafts. Cell Signal (2009) 0.77
Cookie-cutter curriculum is no recipe for success. Science (2011) 0.75
Bacterial expression strategies for several Sus scrofa diacylglycerol kinase alpha constructs: solubility challenges. Sci Rep (2013) 0.75
Desperately seeking Flexner: time to reemphasize basic science in medical education. Acad Med (2013) 0.75
Activation and phosphorylation on Thr-160 of nuclear-targeted CDK2 Is ERK dependent. Ann N Y Acad Sci (2002) 0.75
alpha-Thrombin activates Akt via a nonreceptor tyrosine kinase in IIC9 cells. Ann N Y Acad Sci (2002) 0.75