PubRank

Clemens W G M Löwik

Author PubWeight™ 85.89‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist. J Exp Med 2004 3.88
2 The clinical use of indocyanine green as a near-infrared fluorescent contrast agent for image-guided oncologic surgery. J Surg Oncol 2011 3.24
3 BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis. J Cell Sci 2007 2.95
4 Toward optimization of imaging system and lymphatic tracer for near-infrared fluorescent sentinel lymph node mapping in breast cancer. Ann Surg Oncol 2011 2.67
5 Bone morphogenetic proteins stimulate angiogenesis through osteoblast-derived vascular endothelial growth factor A. Endocrinology 2002 2.49
6 Optical image-guided surgery--where do we stand? Mol Imaging Biol 2011 2.15
7 Mesenchymal stem cells promote engraftment of human umbilical cord blood-derived CD34(+) cells in NOD/SCID mice. Exp Hematol 2002 2.05
8 Bone mineral density in sclerosteosis; affected individuals and gene carriers. J Clin Endocrinol Metab 2005 2.05
9 SOST/sclerostin, an osteocyte-derived negative regulator of bone formation. Cytokine Growth Factor Rev 2005 1.88
10 Wnt but not BMP signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation. J Bone Miner Res 2007 1.76
11 Optical imaging of cancer metastasis to bone marrow: a mouse model of minimal residual disease. Am J Pathol 2002 1.71
12 Near-infrared fluorescence-guided resection of colorectal liver metastases. Cancer 2013 1.71
13 Multiple mechanisms are involved in inhibition of osteoblast differentiation by PTHrP and PTH in KS483 Cells. J Bone Miner Res 2005 1.63
14 Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer. Cancer Res 2007 1.63
15 BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo. Am J Pathol 2007 1.58
16 Randomized, double-blind comparison of indocyanine green with or without albumin premixing for near-infrared fluorescence imaging of sentinel lymph nodes in breast cancer patients. Breast Cancer Res Treat 2011 1.43
17 Osteocyte-derived sclerostin inhibits bone formation: its role in bone morphogenetic protein and Wnt signaling. J Bone Joint Surg Am 2008 1.43
18 Whole-body optical imaging in animal models to assess cancer development and progression. Clin Cancer Res 2007 1.41
19 Downregulation of Wnt signaling by increased expression of Dickkopf-1 and -2 is a prerequisite for late-stage osteoblast differentiation of KS483 cells. J Bone Miner Res 2005 1.39
20 Distinct modes of inhibition by sclerostin on bone morphogenetic protein and Wnt signaling pathways. J Biol Chem 2010 1.38
21 Molecular imaging of tumor angiogenesis using alphavbeta3-integrin targeted multimodal quantum dots. Angiogenesis 2008 1.37
22 Interference with the microenvironmental support impairs the de novo formation of bone metastases in vivo. Cancer Res 2005 1.33
23 Optical image-guided cancer surgery: challenges and limitations. Clin Cancer Res 2013 1.29
24 Clinical translation of ex vivo sentinel lymph node mapping for colorectal cancer using invisible near-infrared fluorescence light. Ann Surg Oncol 2010 1.24
25 Atlas-based whole-body segmentation of mice from low-contrast Micro-CT data. Med Image Anal 2010 1.23
26 Near-infrared fluorescence imaging of liver metastases in rats using indocyanine green. J Surg Res 2011 1.23
27 Hedgehog stimulates only osteoblastic differentiation of undifferentiated KS483 cells. Bone 2003 1.23
28 Peroxisome proliferator-activated receptor gamma (PPARgamma ) as a molecular target for the soy phytoestrogen genistein. J Biol Chem 2002 1.21
29 Image-guided tumor resection using real-time near-infrared fluorescence in a syngeneic rat model of primary breast cancer. Breast Cancer Res Treat 2010 1.17
30 VEGF and inhibitors of TGFbeta type-I receptor kinase synergistically promote blood-vessel formation by inducing alpha5-integrin expression. J Cell Sci 2009 1.15
31 Lack of noggin expression by cancer cells is a determinant of the osteoblast response in bone metastases. Am J Pathol 2007 1.10
32 Optimization of near-infrared fluorescent sentinel lymph node mapping for vulvar cancer. Am J Obstet Gynecol 2011 1.09
33 Dissociation of angiogenesis and osteoclastogenesis during endochondral bone formation in neonatal mice. J Bone Miner Res 2002 1.06
34 Novel intraoperative near-infrared fluorescence camera system for optical image-guided cancer surgery. Mol Imaging 2010 1.05
35 Multimodality imaging reveals a gradual increase in matrix metalloproteinase activity at aneurysmal lesions in live fibulin-4 mice. Circ Cardiovasc Imaging 2010 1.03
36 Optical imaging of oral squamous cell carcinoma and cervical lymph node metastasis. Head Neck 2011 0.98
37 Multicolor fluorescence imaging of traumatic brain injury in a cryolesion mouse model. ACS Chem Neurosci 2012 0.97
38 Near-infrared fluorescence sentinel lymph node mapping of the oral cavity in head and neck cancer patients. Oral Oncol 2012 0.97
39 Multimodal imaging and treatment of bone metastasis. Clin Exp Metastasis 2008 0.97
40 The balance between concurrent activation of ERs and PPARs determines daidzein-induced osteogenesis and adipogenesis. J Bone Miner Res 2004 0.96
41 Dual wavelength tumor targeting for detection of hypopharyngeal cancer using near-infrared optical imaging in an animal model. Int J Cancer 2012 0.95
42 Advances in optical imaging and novel model systems for cancer metastasis research. Clin Exp Metastasis 2007 0.95
43 Detection of oral squamous cell carcinoma and cervical lymph node metastasis using activatable near-infrared fluorescence agents. Arch Otolaryngol Head Neck Surg 2011 0.95
44 Articulated planar reformation for change visualization in small animal imaging. IEEE Trans Vis Comput Graph 2010 0.94
45 Targeting integrins and enhanced permeability and retention (EPR) effect for optical imaging of oral cancer. J Surg Oncol 2011 0.93
46 Near-infrared fluorescence imaging of both colorectal cancer and ureters using a low-dose integrin targeted probe. Ann Surg Oncol 2014 0.92
47 Translational optical imaging in diagnosis and treatment of cancer. Curr Pharm Biotechnol 2012 0.91
48 A transgenic Tie2-GFP athymic mouse model; a tool for vascular biology in xenograft tumors. Biochem Biophys Res Commun 2008 0.91
49 Inhibition of bone resorption and growth of breast cancer in the bone microenvironment. Bone 2008 0.90
50 Celecoxib enhances doxorubicin-induced cytotoxicity in MDA-MB231 cells by NF-kappaB-mediated increase of intracellular doxorubicin accumulation. Eur J Cancer 2006 0.90
51 Automated registration of whole-body follow-up MicroCT data of mice. Med Image Comput Comput Assist Interv 2011 0.89
52 Dual-wavelength imaging of tumor progression by activatable and targeting near-infrared fluorescent probes in a bioluminescent breast cancer model. PLoS One 2012 0.88
53 A novel luciferase fusion protein for highly sensitive optical imaging: from single-cell analysis to in vivo whole-body bioluminescence imaging. Anal Bioanal Chem 2014 0.87
54 Imaging bone morphogenetic protein 7 induced cell cycle arrest in experimental gliomas. Neoplasia 2011 0.87
55 A new paradigm in the treatment of osteoporosis: Wnt pathway proteins and their antagonists. Curr Opin Investig Drugs 2007 0.86
56 Class III β-tubulin, a novel biomarker in the human melanocyte lineage. Differentiation 2013 0.85
57 SOST expression is restricted to the great arteries during embryonic and neonatal cardiovascular development. Dev Dyn 2007 0.84
58 Uncomplicated differentiation of stem cells into bipolar neurons and myelinating glia. Biochem Biophys Res Commun 2008 0.84
59 Automated bone volume and thickness measurements in small animal whole-body MicroCT data. Mol Imaging Biol 2012 0.83
60 Plaque rupture complications in murine atherosclerotic vein grafts can be prevented by TIMP-1 overexpression. PLoS One 2012 0.83
61 Novel early target genes of parathyroid hormone-related peptide in chondrocytes. Endocrinology 2006 0.81
62 Apc bridges Wnt/β-catenin and BMP signaling during osteoblast differentiation of KS483 cells. Exp Cell Res 2011 0.81
63 Novel late response genes of PTHrP in chondrocytes. Horm Res 2006 0.81
64 Optical imaging of treatment-related tumor cell death using a heat shock protein-90 alkylator. Mol Pharm 2013 0.80
65 Prognostic significance of periodic acid-Schiff-positive patterns in primary breast cancer and its lymph node metastases. Breast Cancer Res Treat 2004 0.78
66 2-methoxyestradiol analogue ENMD-1198 reduces breast cancer-induced osteolysis and tumor burden both in vitro and in vivo. Mol Cancer Ther 2011 0.78
67 In vivo 808 nm image-guided photodynamic therapy based on an upconversion theranostic nanoplatform. Nanoscale 2015 0.76
68 CT-based handling and analysis of preclinical multimodality imaging data of bone metastases. Bonekey Rep 2012 0.76
69 An in vitro model that can distinguish between effects on angiogenesis and on established vasculature: actions of TNP-470, marimastat and the tubulin-binding agent Ang-510. Biochem Biophys Res Commun 2009 0.75
70 Identification of receptor-type protein tyrosine phosphatase μ as a new marker for osteocytes. Histochem Cell Biol 2015 0.75
71 Traumatic brain injury: preclinical imaging diagnostic(s) and therapeutic approaches. Curr Pharm Des 2017 0.75
72 Bioluminescence imaging of bone metastasis in rodents. Methods Mol Biol 2012 0.75
73 Microscopic analysis of the localization of two chlorin-based photosensitizers in OSC19 tumors in the mouse oral cavity. Lasers Surg Med 2014 0.75