| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Phase I study of SS1P, a recombinant anti-mesothelin immunotoxin given as a bolus I.V. infusion to patients with mesothelin-expressing mesothelioma, ovarian, and pancreatic cancers.
|
Clin Cancer Res
|
2007
|
3.30
|
|
2
|
Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe.
|
J Clin Invest
|
2007
|
3.01
|
|
3
|
Increased cellular free cholesterol in macrophage-specific Abca1 knock-out mice enhances pro-inflammatory response of macrophages.
|
J Biol Chem
|
2008
|
2.87
|
|
4
|
Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contraction.
|
Immunity
|
2008
|
2.26
|
|
5
|
Mice with a mutation in the thyroid hormone receptor beta gene spontaneously develop thyroid carcinoma: a mouse model of thyroid carcinogenesis.
|
Thyroid
|
2002
|
2.18
|
|
6
|
Mesothelin expression in human lung cancer.
|
Clin Cancer Res
|
2007
|
2.10
|
|
7
|
Ferroportin and iron regulation in breast cancer progression and prognosis.
|
Sci Transl Med
|
2010
|
1.94
|
|
8
|
Improved detection of apoptotic cells in archival paraffin sections: immunohistochemistry using antibodies to cleaved caspase 3.
|
J Histochem Cytochem
|
2002
|
1.92
|
|
9
|
Localization of mesothelin in epithelial ovarian cancer.
|
Appl Immunohistochem Mol Morphol
|
2005
|
1.84
|
|
10
|
Transferable anticancer innate immunity in spontaneous regression/complete resistance mice.
|
Proc Natl Acad Sci U S A
|
2006
|
1.77
|
|
11
|
ACAT2 is localized to hepatocytes and is the major cholesterol-esterifying enzyme in human liver.
|
Circulation
|
2004
|
1.76
|
|
12
|
Cholesterol-regulated translocation of NPC1L1 to the cell surface facilitates free cholesterol uptake.
|
J Biol Chem
|
2005
|
1.75
|
|
13
|
Diphtheria toxin-murine granulocyte-macrophage colony-stimulating factor-induced hepatotoxicity is mediated by Kupffer cells.
|
Mol Cancer Ther
|
2004
|
1.68
|
|
14
|
An unliganded thyroid hormone beta receptor activates the cyclin D1/cyclin-dependent kinase/retinoblastoma/E2F pathway and induces pituitary tumorigenesis.
|
Mol Cell Biol
|
2005
|
1.67
|
|
15
|
Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone beta receptor inhibits mitotic progression.
|
J Clin Invest
|
2006
|
1.37
|
|
16
|
Pancreatic cancer cells express 25-hydroxyvitamin D-1 alpha-hydroxylase and their proliferation is inhibited by the prohormone 25-hydroxyvitamin D3.
|
Carcinogenesis
|
2004
|
1.37
|
|
17
|
Anthrax toxin-induced shock in rats is associated with pulmonary edema and hemorrhage.
|
Microb Pathog
|
2007
|
1.36
|
|
18
|
Inhibition of phosphatidylinositol 3-kinase delays tumor progression and blocks metastatic spread in a mouse model of thyroid cancer.
|
Carcinogenesis
|
2007
|
1.35
|
|
19
|
Topology of NGEP, a prostate-specific cell:cell junction protein widely expressed in many cancers of different grade level.
|
Cancer Res
|
2008
|
1.34
|
|
20
|
Alterations in genomic profiles during tumor progression in a mouse model of follicular thyroid carcinoma.
|
Carcinogenesis
|
2003
|
1.33
|
|
21
|
Interactions between immunity, proliferation and molecular subtype in breast cancer prognosis.
|
Genome Biol
|
2013
|
1.26
|
|
22
|
Spontaneous regression of advanced cancer: identification of a unique genetically determined, age-dependent trait in mice.
|
Proc Natl Acad Sci U S A
|
2003
|
1.25
|
|
23
|
Branched-chain amino acid catabolism: unique segregation of pathway enzymes in organ systems and peripheral nerves.
|
Am J Physiol Endocrinol Metab
|
2003
|
1.21
|
|
24
|
Loss of expression of tropomyosin-1, a novel class II tumor suppressor that induces anoikis, in primary breast tumors.
|
Oncogene
|
2003
|
1.20
|
|
25
|
Mutually exclusive inactivation of DMP1 and ARF/p53 in lung cancer.
|
Cancer Cell
|
2007
|
1.17
|
|
26
|
Regulation of beta-catenin by a novel nongenomic action of thyroid hormone beta receptor.
|
Mol Cell Biol
|
2008
|
1.15
|
|
27
|
Mutant thyroid hormone receptor beta represses the expression and transcriptional activity of peroxisome proliferator-activated receptor gamma during thyroid carcinogenesis.
|
Cancer Res
|
2003
|
1.13
|
|
28
|
Interstitial diphtheria toxin-epidermal growth factor fusion protein therapy produces regressions of subcutaneous human glioblastoma multiforme tumors in athymic nude mice.
|
Clin Cancer Res
|
2005
|
1.11
|
|
29
|
Growth activation alone is not sufficient to cause metastatic thyroid cancer in a mouse model of follicular thyroid carcinoma.
|
Endocrinology
|
2010
|
1.11
|
|
30
|
Inhibition of acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) prevents dietary cholesterol-associated steatosis by enhancing hepatic triglyceride mobilization.
|
J Biol Chem
|
2010
|
1.11
|
|
31
|
A diphtheria toxin-epidermal growth factor fusion protein is cytotoxic to human glioblastoma multiforme cells.
|
Cancer Res
|
2003
|
1.09
|
|
32
|
NGEP, a prostate-specific plasma membrane protein that promotes the association of LNCaP cells.
|
Cancer Res
|
2007
|
1.08
|
|
33
|
Effector mechanisms of the anti-cancer immune responses of macrophages in SR/CR mice.
|
Cancer Immun
|
2006
|
1.02
|
|
34
|
A human bone morphogenetic protein antagonist is down-regulated in renal cancer.
|
Mol Biol Cell
|
2007
|
1.01
|
|
35
|
Suppression of the transformed phenotype of breast cancer by tropomyosin-1.
|
Exp Cell Res
|
2002
|
1.01
|
|
36
|
Cleavage of high-molecular-weight kininogen by elastase and tryptase is inhibited by ferritin.
|
Am J Physiol Lung Cell Mol Physiol
|
2008
|
1.01
|
|
37
|
Resistance to thyroid hormone is modulated in vivo by the nuclear receptor corepressor (NCOR1).
|
Proc Natl Acad Sci U S A
|
2011
|
1.00
|
|
38
|
SKI-606, an Src inhibitor, reduces tumor growth, invasion, and distant metastasis in a mouse model of thyroid cancer.
|
Clin Cancer Res
|
2012
|
0.99
|
|
39
|
Growth factor receptor expression varies among high-grade gliomas and normal brain: epidermal growth factor receptor has excellent properties for interstitial fusion protein therapy.
|
Mol Cancer Ther
|
2003
|
0.98
|
|
40
|
The pituitary tumor-transforming gene promotes angiogenesis in a mouse model of follicular thyroid cancer.
|
Carcinogenesis
|
2006
|
0.97
|
|
41
|
Inhibition of mTORC1 signaling reduces tumor growth but does not prevent cancer progression in a mouse model of thyroid cancer.
|
Carcinogenesis
|
2010
|
0.96
|
|
42
|
Polymorphisms in drug metabolism genes, smoking, and p53 mutations in breast cancer.
|
Mol Carcinog
|
2008
|
0.96
|
|
43
|
Modulation by steroid receptor coactivator-1 of target-tissue responsiveness in resistance to thyroid hormone.
|
Endocrinology
|
2003
|
0.96
|
|
44
|
The Arf-inducing transcription factor Dmp1 encodes a transcriptional activator of amphiregulin, thrombospondin-1, JunB and Egr1.
|
Int J Cancer
|
2010
|
0.95
|
|
45
|
Oncolytic vesicular stomatitis virus induces apoptosis in U87 glioblastoma cells by a type II death receptor mechanism and induces cell death and tumor clearance in vivo.
|
J Virol
|
2011
|
0.95
|
|
46
|
Activation of caspase pathways during iron chelator-mediated apoptosis.
|
J Biol Chem
|
2002
|
0.94
|
|
47
|
Diffuse malignant mesothelioma of the peritoneum and pleura, analysis of markers.
|
Mod Pathol
|
2004
|
0.93
|
|
48
|
Diet-induced obesity increases tumor growth and promotes anaplastic change in thyroid cancer in a mouse model.
|
Endocrinology
|
2013
|
0.92
|
|
49
|
Critical roles of DMP1 in human epidermal growth factor receptor 2/neu-Arf-p53 signaling and breast cancer development.
|
Cancer Res
|
2010
|
0.92
|
|
50
|
A tumor suppressor role for thyroid hormone beta receptor in a mouse model of thyroid carcinogenesis.
|
Endocrinology
|
2004
|
0.91
|
|
51
|
5-Oxo-ETE analogs and the proliferation of cancer cells.
|
Biochim Biophys Acta
|
2005
|
0.91
|
|
52
|
In situ vaccination combined with androgen ablation and regulatory T-cell depletion reduces castration-resistant tumor burden in prostate-specific pten knockout mice.
|
Cancer Res
|
2010
|
0.91
|
|
53
|
Role of DMP1 and its future in lung cancer diagnostics.
|
Expert Rev Mol Diagn
|
2008
|
0.91
|
|
54
|
Dual functions of the steroid hormone receptor coactivator 3 in modulating resistance to thyroid hormone.
|
Mol Cell Biol
|
2005
|
0.91
|
|
55
|
Expression and purification of the recombinant diphtheria fusion toxin DT388IL3 for phase I clinical trials.
|
Protein Expr Purif
|
2004
|
0.90
|
|
56
|
Angiotensin-(1-7) attenuates metastatic prostate cancer and reduces osteoclastogenesis.
|
Prostate
|
2012
|
0.89
|
|
57
|
The spectrum of resistance in SR/CR mice: the critical role of chemoattraction in the cancer/leukocyte interaction.
|
BMC Cancer
|
2010
|
0.85
|
|
58
|
The effect of aging on cellular immunity against cancer in SR/CR mice.
|
Cancer Immunol Immunother
|
2004
|
0.84
|
|
59
|
Perillyl alcohol-mediated inhibition of lung cancer cell line proliferation: potential mechanisms for its chemotherapeutic effects.
|
Toxicol Appl Pharmacol
|
2004
|
0.83
|
|
60
|
Inhibition of tumorigenesis by the thyroid hormone receptor β in xenograft models.
|
Thyroid
|
2013
|
0.82
|
|
61
|
Diphtheria toxin-epidermal growth factor fusion protein and Pseudomonas exotoxin-interleukin 13 fusion protein exert synergistic toxicity against human glioblastoma multiforme cells.
|
Bioconjug Chem
|
2003
|
0.82
|
|
62
|
Novel translocation responses of cytosolic phospholipase A2alpha fluorescent proteins.
|
Biochim Biophys Acta
|
2008
|
0.82
|
|
63
|
Loss of heterozygosity and SOSTDC1 in adult and pediatric renal tumors.
|
J Exp Clin Cancer Res
|
2010
|
0.82
|
|
64
|
Nuclear receptor corepressor (NCOR1) regulates in vivo actions of a mutated thyroid hormone receptor α.
|
Proc Natl Acad Sci U S A
|
2013
|
0.82
|
|
65
|
A histone deacetylase inhibitor improves hypothyroidism caused by a TRα1 mutant.
|
Hum Mol Genet
|
2013
|
0.81
|
|
66
|
Triglyceride depletion in THP-1 cells alters cholesteryl ester physical state and cholesterol efflux.
|
J Lipid Res
|
2002
|
0.81
|
|
67
|
DMP1β, a splice isoform of the tumour suppressor DMP1 locus, induces proliferation and progression of breast cancer.
|
J Pathol
|
2015
|
0.81
|
|
68
|
p27Kip1 is essential for the antiproliferative action of 1,25-dihydroxyvitamin D3 in primary, but not immortalized, mouse embryonic fibroblasts.
|
J Biol Chem
|
2002
|
0.81
|
|
69
|
Intrabody-based strategies for inhibition of vascular endothelial growth factor receptor-2: effects on apoptosis, cell growth, and angiogenesis.
|
FASEB J
|
2003
|
0.80
|
|
70
|
Endogenous synthesis of n-3 polyunsaturated fatty acids in Fat-1 mice is associated with increased mammary gland and liver syndecan-1.
|
PLoS One
|
2011
|
0.79
|
|
71
|
Combination fusion protein therapy of refractory brain tumors: demonstration of efficacy in cell culture.
|
J Neurooncol
|
2003
|
0.79
|
|
72
|
The effect of beta-subunit assembly on function and localization of the colonic H+,K+-ATPase alpha-subunit.
|
Kidney Int
|
2004
|
0.78
|
|
73
|
Novel innate cancer killing activity in humans.
|
Cancer Cell Int
|
2011
|
0.78
|
|
74
|
GMP production and characterization of the bivalent anti-human T cell immunotoxin, A-dmDT390-bisFv(UCHT1) for phase I/II clinical trials.
|
Protein Expr Purif
|
2007
|
0.78
|
|
75
|
Quality control in the apoA-I secretory pathway: deletion of apoA-I helix 6 leads to the formation of cytosolic phospholipid inclusions.
|
J Lipid Res
|
2004
|
0.78
|
|
76
|
In situ immunocytochemical detection of altered membrane composition induced by cell-cell contact in cultured mammalian cells.
|
Microsc Res Tech
|
2008
|
0.77
|
|
77
|
Oncogenic Actions of the Nuclear Receptor Corepressor (NCOR1) in a Mouse Model of Thyroid Cancer.
|
PLoS One
|
2013
|
0.77
|
|
78
|
19-nor-1alpha,25-dihydroxyvitamin D(2) (paricalcitol): effects on clonal proliferation, differentiation, and apoptosis in human leukemic cell lines.
|
J Cancer Res Clin Oncol
|
2003
|
0.77
|
|
79
|
Activation of phosphatidylinositol 3-kinase signaling promotes aberrant pituitary growth in a mouse model of thyroid-stimulating hormone-secreting pituitary tumors.
|
Endocrinology
|
2008
|
0.77
|
|
80
|
Clinico-pathologic findings in medullary cystic kidney disease type 2.
|
Pediatr Nephrol
|
2005
|
0.77
|
|
81
|
Impact of sex, MHC, and age of recipients on the therapeutic effect of transferred leukocytes from cancer-resistant SR/CR mice.
|
BMC Cancer
|
2009
|
0.77
|
|
82
|
Polyploid formation via chromosome duplication induced by CTP:phosphocholine cytidylyltransferase deficiency and Bcl-2 overexpression: identification of two novel endogenous factors.
|
J Histochem Cytochem
|
2005
|
0.75
|
|
83
|
Cancer resistance of SR/CR mice in the genetic knockout backgrounds of leukocyte effector mechanisms: determinations for functional requirements.
|
BMC Cancer
|
2010
|
0.75
|
|
84
|
Halo naevus: a visible case of immunosurveillance in humans?
|
Lancet Oncol
|
2004
|
0.75
|
|
85
|
A nonterminal method for frequent collection of mouse circulating proteins by peritoneal lavage.
|
Anal Biochem
|
2005
|
0.75
|
|
86
|
19-Nor-1alpha,25-dihydroxyvitamin D2 (paricalcitol) exerts anticancer activity against HL-60 cells in vitro at clinically achievable concentrations.
|
J Steroid Biochem Mol Biol
|
2004
|
0.75
|
|
87
|
Use of green fluorescent protein to measure tumor growth in an implanted bladder tumor model.
|
J Urol
|
2002
|
0.75
|
|
88
|
Mass spectrometry identification of circulating alpha-1-B glycoprotein, increased in aged female C57BL/6 mice.
|
Biochim Biophys Acta
|
2006
|
0.75
|