Published in J Allergy Clin Immunol on March 01, 2002
Immunostimulatory oligonucleotides block allergic airway inflammation by inhibiting Th2 cell activation and IgE-mediated cytokine induction. J Exp Med (2005) 1.20
Unique and overlapping gene expression patterns driven by IL-4 and IL-13 in the mouse lung. J Allergy Clin Immunol (2009) 1.12
Allergic airway hyperreactivity increases the risk for corneal allograft rejection. Am J Transplant (2009) 1.04
Immunomodulation of allergic disease. Annu Rev Med (2009) 1.02
CpG and non-CpG oligodeoxynucleotides directly costimulate mouse and human CD4+ T cells through a TLR9- and MyD88-independent mechanism. J Immunol (2011) 0.98
Interferon-alpha/beta receptor-mediated selective induction of a gene cluster by CpG oligodeoxynucleotide 2006. BMC Immunol (2003) 0.94
Immunomodulatory effects of CpG oligodeoxynucleotides on established th2 responses. Clin Diagn Lab Immunol (2002) 0.94
Immunostimulatory oligonucleotides attenuate airways remodeling in allergic monkeys. Am J Respir Crit Care Med (2004) 0.93
Allergen-specific pattern recognition receptor pathways. Curr Opin Immunol (2010) 0.92
Translational mini-review series on Toll-like receptors: Toll-like receptor ligands as novel pharmaceuticals for allergic disorders. Clin Exp Immunol (2007) 0.92
Oral administration of CpG-ODNs suppresses antigen-induced asthma in mice. Clin Exp Immunol (2006) 0.92
Novel chimeric immunomodulatory compounds containing short CpG oligodeoxyribonucleotides have differential activities in human cells. Nucleic Acids Res (2003) 0.91
Antigen-specific tolerance in immunotherapy of Th2-associated allergic diseases. Crit Rev Immunol (2013) 0.90
Inhibition of airway allergic disease by co-administration of flagellin with allergen. J Clin Immunol (2007) 0.84
Reversal of established CD4+ type 2 T helper-mediated allergic airway inflammation and eosinophilia by therapeutic treatment with DNA vaccines limits progression towards chronic inflammation and remodelling. Immunology (2004) 0.84
Adjuvants for allergy vaccines. Hum Vaccin Immunother (2012) 0.82
Allergic rhinitis and genetic components: focus on Toll-like receptors (TLRs) gene polymorphism. Appl Clin Genet (2010) 0.78
Epicutaneous immunization with ovalbumin and CpG induces TH1/TH17 cytokines, which regulate IgE and IgG2a production. J Allergy Clin Immunol (2016) 0.76
New vaccines for Mammalian allergy using molecular approaches. Front Immunol (2014) 0.76
Immunomodulatory Effects of Adjuvants CPG, MPLA, and BCG on the Derp2-Induced Acute Asthma at Early Life in an Animal Model of BALB/c Mice. Inflammation (2016) 0.76
The dichotomy of pathogens and allergens in vaccination approaches. Front Microbiol (2014) 0.75
Dietary intake is associated with respiratory health outcomes and DNA methylation in children with asthma. Allergy Asthma Clin Immunol (2017) 0.75
CpG Immunotherapy in Chenopodium album sensitized mice: The comparison of IFN-gamma, IL-10 and IgE responses in intranasal and subcutaneous administrations. Clin Mol Allergy (2008) 0.75
Treatment with 8-OH-modified adenine (TLR7 ligand)-allergen conjugates decreases T helper type 2-oriented murine airway inflammation. Immunology (2015) 0.75
Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature (2008) 4.85
Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy. Am J Pathol (2006) 3.18
CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function. J Exp Med (2005) 3.03
Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma. Nat Immunol (2010) 3.00
Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway. Nat Immunol (2004) 2.86
A role for immune complexes in enhanced respiratory syncytial virus disease. J Exp Med (2002) 2.34
Altered gene expression profiles in nasal respiratory epithelium reflect stable versus acute childhood asthma. J Allergy Clin Immunol (2005) 2.16
A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma. J Clin Invest (2006) 2.15
Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease. Nature (2009) 2.05
Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells. Nature (2011) 1.91
Importance of cytokines in murine allergic airway disease and human asthma. J Immunol (2010) 1.86
Elevated cytokine levels in children with autism spectrum disorder. J Neuroimmunol (2005) 1.85
Identification of a novel CpG DNA class and motif that optimally stimulate B cell and plasmacytoid dendritic cell functions. J Leukoc Biol (2003) 1.65
A phase I study of the safety and immunogenicity of recombinant hepatitis B surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide adjuvant. Vaccine (2003) 1.60
Innate immune responses of airway epithelium to house dust mite are mediated through beta-glucan-dependent pathways. J Allergy Clin Immunol (2009) 1.44
Allergen uptake, activation, and IL-23 production by pulmonary myeloid DCs drives airway hyperresponsiveness in asthma-susceptible mice. PLoS One (2008) 1.38
The anaphylatoxins bridge innate and adaptive immune responses in allergic asthma. Mol Immunol (2004) 1.35
Complement factor 3 mediates particulate matter-induced airway hyperresponsiveness. Am J Respir Cell Mol Biol (2002) 1.32
Differences in expression, affinity, and function of soluble (s)IL-4Ralpha and sIL-13Ralpha2 suggest opposite effects on allergic responses. J Immunol (2007) 1.29
IL-4 induces IL-13-independent allergic airway inflammation. J Allergy Clin Immunol (2006) 1.25
Immunostimulatory oligonucleotides block allergic airway inflammation by inhibiting Th2 cell activation and IgE-mediated cytokine induction. J Exp Med (2005) 1.20
A protective role for C5a in the development of allergic asthma associated with altered levels of B7-H1 and B7-DC on plasmacytoid dendritic cells. J Immunol (2009) 1.19
Use of immunostimulatory sequence-containing oligonucleotides as topical therapy for genital herpes simplex virus type 2 infection. J Virol (2002) 1.19
Particulate matter-induced airway hyperresponsiveness is lymphocyte dependent. Environ Health Perspect (2010) 1.17
A critical role for C5L2 in the pathogenesis of experimental allergic asthma. J Immunol (2010) 1.16
The potential role of interleukin-17 in severe asthma. Curr Allergy Asthma Rep (2011) 1.15
Mucosal sensitization to German cockroach involves protease-activated receptor-2. Respir Res (2010) 1.15
Complement regulates inhalation tolerance at the dendritic cell/T cell interface. Mol Immunol (2006) 1.14
Suppressive effect of IL-4 on IL-13-induced genes in mouse lung. J Immunol (2005) 1.14
Selective stimulation of IL-4 receptor on smooth muscle induces airway hyperresponsiveness in mice. J Exp Med (2011) 1.13
Foxa2 programs Th2 cell-mediated innate immunity in the developing lung. J Immunol (2010) 1.13
Partial restoration of T-cell function in aged mice by in vitro blockade of the PD-1/ PD-L1 pathway. Aging Cell (2010) 1.12
Unique and overlapping gene expression patterns driven by IL-4 and IL-13 in the mouse lung. J Allergy Clin Immunol (2009) 1.12
Expression and regulation of small proline-rich protein 2 in allergic inflammation. Am J Respir Cell Mol Biol (2005) 1.11
Usefulness and optimization of mouse models of allergic airway disease. J Allergy Clin Immunol (2008) 1.10
Differences in candidate gene association between European ancestry and African American asthmatic children. PLoS One (2011) 1.09
Induction of interferon-gamma from natural killer cells by immunostimulatory CpG DNA is mediated through plasmacytoid-dendritic-cell-produced interferon-alpha and tumour necrosis factor-alpha. Immunology (2006) 1.09
TLR2-mediated activation of neutrophils in response to German cockroach frass. J Immunol (2008) 1.08
A TLR2 agonist in German cockroach frass activates MMP-9 release and is protective against allergic inflammation in mice. J Immunol (2009) 1.04
Protease-activated receptor 2 activation of myeloid dendritic cells regulates allergic airway inflammation. Respir Res (2011) 1.03
Caffeine modulates TNF-alpha production by cord blood monocytes: the role of adenosine receptors. Pediatr Res (2009) 1.01
Nonhematopoietic NADPH oxidase regulation of lung eosinophilia and airway hyperresponsiveness in experimentally induced asthma. Am J Physiol Lung Cell Mol Physiol (2007) 0.98
Selective immune redirection in humans with ragweed allergy by injecting Amb a 1 linked to immunostimulatory DNA. J Allergy Clin Immunol (2004) 0.98
Differences in susceptibility to German cockroach frass and its associated proteases in induced allergic inflammation in mice. Respir Res (2007) 0.97
Local and systemic effects of intranodally injected CpG-C immunostimulatory-oligodeoxyribonucleotides in macaques. J Immunol (2006) 0.96
Indoor particulate matter increases asthma morbidity in children with non-atopic and atopic asthma. Ann Allergy Asthma Immunol (2011) 0.96
Negative regulation of TLR9-mediated IFN-alpha induction by a small-molecule, synthetic TLR7 ligand. J Leukoc Biol (2007) 0.95
Downregulation of glutathione S-transferase pi in asthma contributes to enhanced oxidative stress. J Allergy Clin Immunol (2011) 0.94
Polymorphisms in the novel gene acyloxyacyl hydroxylase (AOAH) are associated with asthma and associated phenotypes. J Allergy Clin Immunol (2006) 0.94
Plasminogen activator inhibitor-1 mitigates brain injury in a rat model of infection-sensitized neonatal hypoxia-ischemia. Cereb Cortex (2012) 0.93
Intrauterine Inflammation and Maternal Exposure to Ambient PM2.5 during Preconception and Specific Periods of Pregnancy: The Boston Birth Cohort. Environ Health Perspect (2016) 0.91
Polymyxin B enhances ISS-mediated immune responses across multiple species. Cell Immunol (2004) 0.91
Correlation between serum caffeine levels and changes in cytokine profile in a cohort of preterm infants. J Pediatr (2010) 0.91
Innate lymphoid cells wield a double-edged sword. Nat Immunol (2011) 0.91
Novel chimeric immunomodulatory compounds containing short CpG oligodeoxyribonucleotides have differential activities in human cells. Nucleic Acids Res (2003) 0.91
Identification of Cd101 as a susceptibility gene for Novosphingobium aromaticivorans-induced liver autoimmunity. J Immunol (2011) 0.90
A nonredundant role for mouse Serpinb3a in the induction of mucus production in asthma. J Allergy Clin Immunol (2010) 0.90
Placenta growth factor augments airway hyperresponsiveness via leukotrienes and IL-13. J Clin Invest (2015) 0.90
Differential colonization with segmented filamentous bacteria and Lactobacillus murinus do not drive divergent development of diet-induced obesity in C57BL/6 mice. Mol Metab (2013) 0.89
IL-1 Receptor antagonist as a positional candidate gene in a murine model of allergic asthma. Immunogenetics (2006) 0.88
A dual role for complement in allergic asthma. Curr Opin Pharmacol (2007) 0.88
Matrix metalloproteinase 8 contributes to solubilization of IL-13 receptor alpha2 in vivo. J Allergy Clin Immunol (2008) 0.88
Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice. BMC Immunol (2009) 0.88
Evolving strategies for the prevention of influenza infection: potential for multistrain targeting. BioDrugs (2006) 0.87
Identification of ATPAF1 as a novel candidate gene for asthma in children. J Allergy Clin Immunol (2011) 0.86
Palivizumab epitope-displaying virus-like particles protect rodents from RSV challenge. J Clin Invest (2015) 0.85
Interleukin 13 and the evolution of asthma therapy. Am J Clin Exp Immunol (2012) 0.85
Characterization of a novel PMA-inducible pathway of interleukin-13 gene expression in T cells. Immunology (2006) 0.85
Source of biomass cooking fuel determines pulmonary response to household air pollution. Am J Respir Cell Mol Biol (2014) 0.84
Immunostimulatory DNA as a vaccine adjuvant. Expert Rev Vaccines (2007) 0.83
A minimal human immunostimulatory CpG motif that potently induces IFN-gamma and IFN-alpha production. Eur J Immunol (2003) 0.83
Distinct roles of Cdc42 in thymopoiesis and effector and memory T cell differentiation. PLoS One (2011) 0.83
Differential control of CD4(+) T-cell subsets by the PD-1/PD-L1 axis in a mouse model of allergic asthma. Eur J Immunol (2015) 0.81
Interactive effect of STAT6 and IL13 gene polymorphisms on eczema status: results from a longitudinal and a cross-sectional study. BMC Med Genet (2013) 0.81
Encapsulating immunostimulatory CpG oligonucleotides in listeriolysin O-liposomes promotes a Th1-type response and CTL activity. Mol Pharm (2012) 0.81
IL-13 receptor α2 contributes to development of experimental allergic asthma. J Allergy Clin Immunol (2013) 0.79
Tubulin polymerization modulates interleukin-2 receptor signal transduction in human T cells. J Recept Signal Transduct Res (2006) 0.78
I-Tim-izing the pathways of counter-regulation. Nat Immunol (2003) 0.77
Atorvastatin affects interleukin-2 signaling by altering the lipid raft enrichment of the interleukin-2 receptor beta chain. J Investig Med (2005) 0.76
Local induction of a specific Th1 immune response by allergen linked immunostimulatory DNA in the nasal explants of ragweed-allergic subjects. Allergol Int (2009) 0.76
Modulation of immunogenicity and allergenicity by controlling the number of immunostimulatory oligonucleotides linked to Amb a 1. J Allergy Clin Immunol (2006) 0.76
One-pot synthesis, purification, and formulation of bionanoparticle-CpG oligodeoxynucleotide hepatitis B surface antigen conjugate vaccine via tangential flow filtration. Bioconjug Chem (2007) 0.75
Allergy and hypersensitivity. Curr Opin Immunol (2010) 0.75
Histamine-releasing factor: a promising therapeutic target for food allergy. J Clin Invest (2017) 0.75