Published in Blood on April 15, 2002
Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction. Immunity (2008) 6.08
Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen. J Exp Med (2005) 3.70
Opposing functions of the T cell receptor kinase ZAP-70 in immunity and tolerance differentially titrate in response to nucleotide substitutions. Immunity (2007) 1.83
Host defense pathways: role of redundancy and compensation in infectious disease phenotypes. Immunity (2011) 1.57
Patient-centred screening for primary immunodeficiency: a multi-stage diagnostic protocol designed for non-immunologists. Clin Exp Immunol (2006) 1.49
Impaired in vitro regulatory T cell function associated with Wiskott-Aldrich syndrome. Clin Immunol (2007) 1.40
Arthritogenic self-reactive CD4+ T cells acquire an FR4hiCD73hi anergic state in the presence of Foxp3+ regulatory T cells. J Immunol (2011) 1.32
Autoimmunity in wiskott-Aldrich syndrome: an unsolved enigma. Front Immunol (2012) 1.27
Autoimmunity in IgA deficiency: revisiting the role of IgA as a silent housekeeper. J Clin Immunol (2008) 1.17
Autoimmunity and inflammation in X-linked agammaglobulinemia. J Clin Immunol (2014) 1.01
Autoimmunity in severe combined immunodeficiency (SCID): lessons from patients and experimental models. J Clin Immunol (2008) 0.97
Persistent systemic inflammation and atypical enterocolitis in patients with NEMO syndrome. Clin Immunol (2009) 0.92
Know Thyself: NK-Cell Inhibitory Receptors Prompt Self-Tolerance, Education, and Viral Control. Front Immunol (2014) 0.91
From murine to human nude/SCID: the thymus, T-cell development and the missing link. Clin Dev Immunol (2012) 0.89
N-WASP has the ability to compensate for the loss of WASP in macrophage podosome formation and chemotaxis. Exp Cell Res (2010) 0.88
Selective Treg reconstitution during lymphopenia normalizes DC costimulation and prevents graft-versus-host disease. J Clin Invest (2015) 0.88
Autoimmunity in common variable immunodeficiency. J Clin Immunol (2008) 0.88
Selective IgA deficiency: clinical and laboratory features of 118 children in Turkey. J Clin Immunol (2012) 0.87
Apoptosis regulators Fas and Bim synergistically control T-lymphocyte homeostatic proliferation. Eur J Immunol (2010) 0.86
TLR cross-talk confers specificity to innate immunity. Int Rev Immunol (2014) 0.86
Postmortem diagnosis of chronic granulomatous disease: how worthwhile is it? J Clin Pathol (2005) 0.83
Protein microarrays: a new tool for the study of autoantibodies in immunodeficiency. Front Immunol (2015) 0.80
Inborn errors in immunity: unique natural models to dissect oral immunity. J Dent Res (2015) 0.79
Profile of autoantibodies against phosphorylcholine and cross-reactivity to oxidation-specific neoantigens in selective IgA deficiency with or without autoimmune diseases. J Clin Immunol (2010) 0.79
Autoimmunity in severe combined immunodeficiency (SCID). Blood (2002) 0.77
Occurrence of autoantibodies for gastrointestinal autoimmune diseases in children with common variable immune deficiency and selected IgA deficiency. Prz Gastroenterol (2013) 0.76
Hyper-IgE syndrome and autoimmunity in Mexican children. Pediatr Nephrol (2006) 0.76
Genetic cause of immune dysregulation - one gene or two? J Clin Invest (2016) 0.75
Mechanism-Based Strategies for the Management of Autoimmunity and Immune Dysregulation in Primary Immunodeficiencies. J Allergy Clin Immunol Pract (2016) 0.75
A functional PTPN22 polymorphism associated with several autoimmune diseases is not associated with IgA deficiency in the Spanish population. BMC Med Genet (2006) 0.75
Clinical predictors of autoimmune and severe atopic disease in pediatric heart transplant recipients. Pediatr Transplant (2013) 0.75
A novel mutation associated with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy. Ann Allergy Asthma Immunol (2008) 0.75
Is hemophagocytic lymphohistiocytosis an autoimmune disease? Blood (2002) 0.75
X-linked hyper IgM (HIGM1) in an African kindred: the first report from South Africa. BMC Pediatr (2003) 0.75
Is Graves' disease a primary immunodeficiency? New immunological perspectives on an endocrine disease. BMC Med (2017) 0.75
Hyperimmunoglobulin E syndrome: Genetics, immunopathogenesis, clinical findings, and treatment modalities. J Res Med Sci (2017) 0.75
Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity. Immunity (2006) 4.75
Early-onset stroke and vasculopathy associated with mutations in ADA2. N Engl J Med (2014) 4.70
Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I. J Exp Med (2010) 3.98
Long-term survival and transplantation of haemopoietic stem cells for immunodeficiencies: report of the European experience 1968-99. Lancet (2003) 3.44
Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage. Science (2013) 3.33
Transplantation of hematopoietic stem cells and long-term survival for primary immunodeficiencies in Europe: entering a new century, do we do better? J Allergy Clin Immunol (2010) 2.35
Osteoclast-poor human osteopetrosis due to mutations in the gene encoding RANKL. Nat Genet (2007) 2.04
Secondary autoimmune diseases occurring after HSCT for an autoimmune disease: a retrospective study of the EBMT Autoimmune Disease Working Party. Blood (2011) 1.89
Chloride channel ClCN7 mutations are responsible for severe recessive, dominant, and intermediate osteopetrosis. J Bone Miner Res (2003) 1.55
Fulminant mulch pneumonitis: an emergency presentation of chronic granulomatous disease. Clin Infect Dis (2007) 1.52
Intracerebral large artery disease in Aicardi-Goutières syndrome implicates SAMHD1 in vascular homeostasis. Dev Med Child Neurol (2010) 1.47
Clinical outcome in children with chronic granulomatous disease managed conservatively or with hematopoietic stem cell transplantation. J Allergy Clin Immunol (2013) 1.46
Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations. Am J Hum Genet (2008) 1.41
Biallelic mutations in IRF8 impair human NK cell maturation and function. J Clin Invest (2016) 1.39
Reduced anti-PRP antibody response to Hib immunisation in preterm (<32 weeks) UK infants who received inactivated polio (eIPV). Vaccine (2007) 1.38
Mutations in STAT3 and diagnostic guidelines for hyper-IgE syndrome. J Allergy Clin Immunol (2010) 1.36
Autoantibodies against type I interferons as an additional diagnostic criterion for autoimmune polyendocrine syndrome type I. J Clin Endocrinol Metab (2008) 1.26
Treosulfan-based conditioning regimens for hematopoietic stem cell transplantation in children with primary immunodeficiency: United Kingdom experience. Blood (2011) 1.24
Clinical features that identify children with primary immunodeficiency diseases. Pediatrics (2011) 1.13
Haemophilus influenzae type b immunization in infants in the United Kingdom: effects of diphtheria/tetanus/acellular pertussis/Hib combination vaccine, significant prematurity, and a fourth dose. Pediatrics (2006) 1.13
Unrelated donor and HLA-identical sibling haematopoietic stem cell transplantation cure chronic granulomatous disease with good long-term outcome and growth. Br J Haematol (2009) 1.11
Long-term immune reconstitution after anti-CD52-treated or anti-CD34-treated hematopoietic stem cell transplantation for severe T-lymphocyte immunodeficiency. J Allergy Clin Immunol (2007) 1.06
Mutations in OSTM1 (grey lethal) define a particularly severe form of autosomal recessive osteopetrosis with neural involvement. J Bone Miner Res (2006) 1.01
Impaired T(H)17 responses in patients with chronic mucocutaneous candidiasis with and without autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy. J Allergy Clin Immunol (2010) 1.01
STAT2 deficiency and susceptibility to viral illness in humans. Proc Natl Acad Sci U S A (2013) 1.01
Risks of immune system treatments. Science (2010) 1.00
Clinical and immunologic outcome of patients with cartilage hair hypoplasia after hematopoietic stem cell transplantation. Blood (2010) 1.00
Molecular and clinical heterogeneity in CLCN7-dependent osteopetrosis: report of 20 novel mutations. Hum Mutat (2010) 0.99
Management of autoimmune diseases after haematopoietic stem cell transplantation. Br J Haematol (2012) 0.99
Environmental monitoring for gastroenteric viruses in a pediatric primary immunodeficiency unit. J Clin Microbiol (2006) 0.97
Sequential decisions on FAS sequencing guided by biomarkers in patients with lymphoproliferation and autoimmune cytopenia. Haematologica (2013) 0.95
Use of a heminested reverse transcriptase PCR assay for detection of astrovirus in environmental swabs from an outbreak of gastroenteritis in a pediatric primary immunodeficiency unit. J Clin Microbiol (2005) 0.94
Contamination of the hospital environment with gastroenteric viruses: comparison of two pediatric wards over a winter season. J Clin Microbiol (2008) 0.93
Severe food-allergic reactions in children across the UK and Ireland, 1998-2000. Acta Paediatr (2005) 0.92
Mevalonic aciduria cured by bone marrow transplantation. N Engl J Med (2007) 0.92
Forkhead box protein 3 (FOXP3) mutations lead to increased TH17 cell numbers and regulatory T-cell instability. J Allergy Clin Immunol (2011) 0.91
Treatment of primary angiitis of the central nervous system in childhood with mycophenolate mofetil. Rheumatology (Oxford) (2010) 0.90
Adenovirus type F subtype 41 causing disseminated disease following bone marrow transplantation for immunodeficiency. J Clin Microbiol (2005) 0.90
Treatment of CD40 ligand deficiency by hematopoietic stem cell transplantation: a survey of the European experience, 1993-2002. Blood (2003) 0.89
Performance of current guidelines for diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis. Arthritis Rheumatol (2014) 0.87
Deregulated production of protective cytokines in response to Candida albicans infection in patients with chronic mucocutaneous candidiasis. Infect Immun (2003) 0.87
Hematopoietic stem cell transplantation corrects the immunologic abnormalities associated with immunodeficiency-centromeric instability-facial dysmorphism syndrome. Pediatrics (2007) 0.86
Mucormycosis in chronic granulomatous disease: association with iatrogenic immunosuppression. J Allergy Clin Immunol (2009) 0.86
GvHD-associated cytokine polymorphisms do not associate with Omenn syndrome rather than T-B- SCID in patients with defects in RAG genes. Clin Immunol (2007) 0.86
Advances in hematopoietic stem cell transplantation for primary immunodeficiency. Immunol Allergy Clin North Am (2008) 0.86
Hematopoietic stem cell transplantation for primary immunodeficiency diseases. Ann N Y Acad Sci (2011) 0.86
Anti-pneumococcal antibody titre measurement: what useful information does it yield? J Clin Pathol (2006) 0.86
Idiopathic infantile pyoderma gangrenosum with stridor responsive to infliximab. Pediatr Dermatol (2009) 0.85
Recently identified factors predisposing children to infectious diseases. Curr Opin Infect Dis (2008) 0.85
Cord blood stem cell transplantation in primary immune deficiencies. Curr Opin Allergy Clin Immunol (2007) 0.84
Chronic granulomatous disease presenting as fulminant Aspergillus pneumonitis: a lethal combination? Pediatr Crit Care Med (2009) 0.83
Haematopoietic stem cell transplantation (HSCT) in severe autoimmune diseases: analysis of UK outcomes from the British Society of Blood and Marrow Transplantation (BSBMT) data registry 1997-2009. Br J Haematol (2012) 0.82
Clinical, molecular, and cellular immunologic findings in patients with SP110-associated veno-occlusive disease with immunodeficiency syndrome. J Allergy Clin Immunol (2012) 0.82
Health related quality of life and emotional health in children with chronic granulomatous disease: a comparison of those managed conservatively with those that have undergone haematopoietic stem cell transplant. J Clin Immunol (2012) 0.82
Absidia corymbifera in a patient with chronic granulomatous disease. Pediatr Infect Dis J (2007) 0.81
Three novel mutations of the CIITA gene in MHC class II-deficient patients with a severe immunodeficiency. Immunogenetics (2002) 0.81
Autologous T cell depleted haematopoietic stem cell transplantation in children with severe juvenile idiopathic arthritis in the UK (2000-2007). Mol Immunol (2009) 0.80
Omenn's syndrome occurring in patients without mutations in recombination activating genes. Clin Immunol (2005) 0.80
Phenotypic variations of cartilage hair hypoplasia: granulomatous skin inflammation and severe T cell immunodeficiency as initial clinical presentation in otherwise well child with short stature. J Clin Immunol (2013) 0.80
RANKL cytokine: from pioneer of the osteoimmunology era to cure for a rare disease. Clin Dev Immunol (2013) 0.80
Acute haemorrhagic oedema of infancy--a case of benign cutaneous leucocytoclastic vasculitis. Rheumatology (Oxford) (2010) 0.80
Emotional and behavioural difficulties in chronic granulomatous disease. Arch Dis Child (2011) 0.79
The immunocompromised host: the patient with recurrent infection. Adv Exp Med Biol (2004) 0.78
Autologous hematopoietic stem cell transplantation for childhood autoimmune disease. Pediatr Clin North Am (2010) 0.78
Immunological characteristics and T-cell receptor clonal diversity in children with systemic juvenile idiopathic arthritis undergoing T-cell-depleted autologous stem cell transplantation. Immunology (2014) 0.78
Polymorphous lymphoproliferative disorder with Hodgkin-like features in common γ-chain-deficient severe combined immunodeficiency. J Allergy Clin Immunol (2010) 0.78
ICON: the early diagnosis of congenital immunodeficiencies. J Clin Immunol (2014) 0.77
Severe combined immunodeficiency in Serbia and Montenegro between years 1986 and 2010: a single-center experience. J Clin Immunol (2014) 0.77
Outcome of hematopoietic stem cell transplantation in severe combined immune deficiency with central nervous system viral infection. Pediatr Infect Dis J (2007) 0.77
Cognitive ability in children with chronic granulomatous disease: a comparison of those managed conservatively with those who have undergone hematopoietic stem cell transplant. Neuropediatrics (2013) 0.76
Clinical experience in T cell deficient patients. Allergy Asthma Clin Immunol (2010) 0.76
The 10 warning signs: a time for a change? Curr Opin Allergy Clin Immunol (2012) 0.76
Haploidentical hematopoietic stem cell transplantation can lead to viral clearance in severe combined immunodeficiency. J Allergy Clin Immunol (2013) 0.76
Long-term follow-up and prognosis of chronic granulomatous disease in Yugoslavia: is there a role for early bone marrow transplantation? J Clin Immunol (2003) 0.75
Comment on Plebani et al.'s report. Clin Immunol (2003) 0.75
Bone marrow transplantation for Nijmegan breakage syndrome. J Pediatr Hematol Oncol (2005) 0.75
Infection-Related Death among Persons with Refractory Juvenile Idiopathic Arthritis. Emerg Infect Dis (2016) 0.75
Graves' immune reconstitution inflammatory syndrome in childhood. Thyroid (2013) 0.75
Pityriasis lichenoides in a girl with the granulomatous form of common variable immunodeficiency. Pediatr Dermatol (2002) 0.75
Prevalence of Cryptosporidium Carriage and Disease in Children With Primary Immune Deficiencies Undergoing Hematopoietic Stem Cell Transplant in Northern Europe. Pediatr Infect Dis J (2017) 0.75
Prevalence of Cryptosporidium Carriage and Disease in Children with Primary Immune-Deficiencies Undergoing Hematopoietic Stem Cell Transplant in Northern Europe. Pediatr Infect Dis J (2016) 0.75
New findings in primary immunodeficiency. Adv Exp Med Biol (2009) 0.75