John A Leigh

Author PubWeight™ 43.53‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The genome of M. acetivorans reveals extensive metabolic and physiological diversity. Genome Res 2002 4.58
2 Metabolic modeling of a mutualistic microbial community. Mol Syst Biol 2007 2.40
3 Markerless mutagenesis in Methanococcus maripaludis demonstrates roles for alanine dehydrogenase, alanine racemase, and alanine permease. J Bacteriol 2005 1.92
4 Disruption of the operon encoding Ehb hydrogenase limits anabolic CO2 assimilation in the archaeon Methanococcus maripaludis. J Bacteriol 2006 1.58
5 Quantitative proteomics of the archaeon Methanococcus maripaludis validated by microarray analysis and real time PCR. Mol Cell Proteomics 2006 1.49
6 Protein complexing in a methanogen suggests electron bifurcation and electron delivery from formate to heterodisulfide reductase. Proc Natl Acad Sci U S A 2010 1.48
7 Structural underpinnings of nitrogen regulation by the prototypical nitrogen-responsive transcriptional factor NrpR. Structure 2010 1.40
8 Comparison of spectral counting and metabolic stable isotope labeling for use with quantitative microbial proteomics. Analyst 2006 1.29
9 Functionally distinct genes regulated by hydrogen limitation and growth rate in methanogenic Archaea. Proc Natl Acad Sci U S A 2007 1.29
10 Regulation of nif expression in Methanococcus maripaludis: roles of the euryarchaeal repressor NrpR, 2-oxoglutarate, and two operators. J Biol Chem 2004 1.26
11 A novel repressor of nif and glnA expression in the methanogenic archaeon Methanococcus maripaludis. Mol Microbiol 2003 1.21
12 Essential anaplerotic role for the energy-converting hydrogenase Eha in hydrogenotrophic methanogenesis. Proc Natl Acad Sci U S A 2012 1.15
13 Formate-dependent H2 production by the mesophilic methanogen Methanococcus maripaludis. Appl Environ Microbiol 2008 1.15
14 Parallel evolution of transcriptome architecture during genome reorganization. Genome Res 2011 1.14
15 Continuous culture of Methanococcus maripaludis under defined nutrient conditions. FEMS Microbiol Lett 2004 1.13
16 Function and regulation of the formate dehydrogenase genes of the methanogenic archaeon Methanococcus maripaludis. J Bacteriol 2003 1.12
17 Regulation of nitrogenase by 2-oxoglutarate-reversible, direct binding of a PII-like nitrogen sensor protein to dinitrogenase. Proc Natl Acad Sci U S A 2006 1.11
18 Global responses of Methanococcus maripaludis to specific nutrient limitations and growth rate. J Bacteriol 2008 1.09
19 Quantitative proteomics of nutrient limitation in the hydrogenotrophic methanogen Methanococcus maripaludis. BMC Microbiol 2009 1.09
20 Protein abundance ratios for global studies of prokaryotes. Proteomics 2007 1.09
21 Roles of coenzyme F420-reducing hydrogenases and hydrogen- and F420-dependent methylenetetrahydromethanopterin dehydrogenases in reduction of F420 and production of hydrogen during methanogenesis. J Bacteriol 2008 1.04
22 2-Oxoglutarate and the PII homologues NifI1 and NifI2 regulate nitrogenase activity in cell extracts of Methanococcus maripaludis. Mol Microbiol 2005 0.98
23 Regulatory response of Methanococcus maripaludis to alanine, an intermediate nitrogen source. J Bacteriol 2002 0.98
24 Functional responses of methanogenic archaea to syntrophic growth. ISME J 2012 0.92
25 H2-independent growth of the hydrogenotrophic methanogen Methanococcus maripaludis. MBio 2013 0.91
26 Genetic systems for hydrogenotrophic methanogens. Methods Enzymol 2011 0.90
27 Effects of H2 and formate on growth yield and regulation of methanogenesis in Methanococcus maripaludis. J Bacteriol 2013 0.87
28 A systems level predictive model for global gene regulation of methanogenesis in a hydrogenotrophic methanogen. Genome Res 2013 0.87
29 Diverse homologues of the archaeal repressor NrpR function similarly in nitrogen regulation. FEMS Microbiol Lett 2007 0.85
30 Genetic screen for regulatory mutations in Methanococcus maripaludis and its use in identification of induction-deficient mutants of the euryarchaeal repressor NrpR. Appl Environ Microbiol 2007 0.84
31 Overlapping repressor binding sites regulate expression of the Methanococcus maripaludis glnK(1) operon. Mol Microbiol 2009 0.83
32 VhuD facilitates electron flow from H2 or formate to heterodisulfide reductase in Methanococcus maripaludis. J Bacteriol 2013 0.82
33 Comprehensive computational analysis of Hmd enzymes and paralogs in methanogenic Archaea. BMC Evol Biol 2009 0.81
34 Interdomain conjugal transfer of DNA from bacteria to archaea. Appl Environ Microbiol 2010 0.80
35 NifI inhibits nitrogenase by competing with Fe protein for binding to the MoFe protein. Biochem Biophys Res Commun 2007 0.77
36 Phenotypic evidence that the function of the [Fe]-hydrogenase Hmd in Methanococcus maripaludis requires seven hcg (hmd co-occurring genes) but not hmdII. FEMS Microbiol Lett 2013 0.76