Published in J Cell Sci on May 01, 2002
Hypoxic induction of an HIF-1alpha-dependent bFGF autocrine loop drives angiogenesis in human endothelial cells. Blood (2005) 1.74
Low physiologic oxygen tensions reduce proliferation and differentiation of human multipotent mesenchymal stromal cells. BMC Cell Biol (2010) 1.62
Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects. Dev Biol (2008) 1.29
Endothelial heparan sulfate in angiogenesis. Prog Mol Biol Transl Sci (2010) 1.02
Cellular oxygen sensing in health and disease. Pediatr Nephrol (2007) 0.97
Testing clinical therapeutic angiogenesis using basic fibroblast growth factor (FGF-2). Br J Pharmacol (2003) 0.92
Cobalt chloride decreases fibroblast growth factor-21 expression dependent on oxidative stress but not hypoxia-inducible factor in Caco-2 cells. Toxicol Appl Pharmacol (2012) 0.84
Differential regulation of the attachment of Kaposi's sarcoma-associated herpesvirus (KSHV)-infected human B cells to extracellular matrix by KSHV-encoded gB and cellular alphaV integrins. Cell Microbiol (2008) 0.81
Anti-tumor effects of fibroblast growth factor-binding protein (FGF-BP) knockdown in colon carcinoma. Mol Cancer (2011) 0.78
Elevation of plasma basic fibroblast growth factor after nocturnal hypoxic events in patients with obstructive sleep apnea syndrome. Springerplus (2013) 0.75
Peroxynitrite upregulates angiogenic factors VEGF-A, BFGF, and HIF-1α in human corneal limbal epithelial cells. Invest Ophthalmol Vis Sci (2014) 0.75
Anti-angiogenic activity of rPAI-1(23) and vasa vasorum regression. Trends Cardiovasc Med (2013) 0.75
Endothelial cell metabolism in health and disease: impact of hypoxia. EMBO J (2017) 0.75
Results of a double-blind, placebo-controlled study to assess the safety of intramuscular injection of hepatocyte growth factor plasmid to improve limb perfusion in patients with critical limb ischemia. Circulation (2008) 2.82
Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis. Nature (2011) 2.47
Syndecans: new kids on the signaling block. Circ Res (2005) 2.43
Endothelial-derived angiocrine signals induce and sustain regenerative lung alveolarization. Cell (2011) 2.42
VEGF receptor 2 endocytic trafficking regulates arterial morphogenesis. Dev Cell (2010) 2.37
ALK1 signaling inhibits angiogenesis by cooperating with the Notch pathway. Dev Cell (2012) 2.14
Role of angiogenesis in cardiovascular disease: a critical appraisal. Circulation (2005) 2.13
The FGF system has a key role in regulating vascular integrity. J Clin Invest (2008) 2.09
Medical device development: from prototype to regulatory approval. Circulation (2004) 1.90
Selective regulation of arterial branching morphogenesis by synectin. Dev Cell (2006) 1.77
Branching morphogenesis. Circ Res (2008) 1.77
Angiogenesis-dependent and independent phases of intimal hyperplasia. Circulation (2004) 1.71
FGF regulates TGF-β signaling and endothelial-to-mesenchymal transition via control of let-7 miRNA expression. Cell Rep (2012) 1.63
Fibroblast growth factor regulation of neovascularization. Curr Opin Hematol (2008) 1.56
FGF-dependent regulation of VEGF receptor 2 expression in mice. J Clin Invest (2011) 1.56
The neuropilin 1 cytoplasmic domain is required for VEGF-A-dependent arteriogenesis. Dev Cell (2013) 1.54
Myocardial hypertrophy in the absence of external stimuli is induced by angiogenesis in mice. J Clin Invest (2007) 1.49
Post-market approval surveillance: a call for a more integrated and comprehensive approach. Circulation (2004) 1.49
ERK1/2-Akt1 crosstalk regulates arteriogenesis in mice and zebrafish. J Clin Invest (2010) 1.45
VEGF signaling inside vascular endothelial cells and beyond. Curr Opin Cell Biol (2012) 1.44
Vascular endothelial growth factor and semaphorin induce neuropilin-1 endocytosis via separate pathways. Circ Res (2008) 1.43
Clustering induces redistribution of syndecan-4 core protein into raft membrane domains. J Biol Chem (2002) 1.43
Neuropilin-1-VEGFR-2 complexing requires the PDZ-binding domain of neuropilin-1. J Biol Chem (2008) 1.38
Syndecan-4 regulates subcellular localization of mTOR Complex2 and Akt activation in a PKCalpha-dependent manner in endothelial cells. Mol Cell (2008) 1.36
Suppression of RhoG activity is mediated by a syndecan 4-synectin-RhoGDI1 complex and is reversed by PKCalpha in a Rac1 activation pathway. J Cell Biol (2009) 1.36
Normal levels of anticoagulant heparan sulfate are not essential for normal hemostasis. J Clin Invest (2003) 1.34
Probucol prevents early coronary heart disease and death in the high-density lipoprotein receptor SR-BI/apolipoprotein E double knockout mouse. Proc Natl Acad Sci U S A (2003) 1.33
Syndecan-4 clustering induces cell migration in a PDZ-dependent manner. Circ Res (2006) 1.31
Role of extracellular sialic acid in regulation of neuronal and network excitability in the rat hippocampus. J Neurosci (2007) 1.31
Fibroblast growth factor 2 endocytosis in endothelial cells proceed via syndecan-4-dependent activation of Rac1 and a Cdc42-dependent macropinocytic pathway. J Cell Sci (2004) 1.30
Regulation of protein kinase B/Akt activity and Ser473 phosphorylation by protein kinase Calpha in endothelial cells. Cell Signal (2004) 1.29
Fibroblast growth factor-specific modulation of cellular response by syndecan-4. J Cell Biol (2002) 1.26
The extracellular matrix and blood vessel formation: not just a scaffold. J Cell Mol Med (2007) 1.25
Translational physiology: porcine models of human coronary artery disease: implications for preclinical trials of therapeutic angiogenesis. J Appl Physiol (1985) (2003) 1.25
Endothelial ERK signaling controls lymphatic fate specification. J Clin Invest (2013) 1.24
PKCalpha activates eNOS and increases arterial blood flow in vivo. Circ Res (2005) 1.22
Non-canonical fibroblast growth factor signalling in angiogenesis. Cardiovasc Res (2007) 1.22
Regulation of Notch signaling by Drosophila heparan sulfate 3-O sulfotransferase. J Cell Biol (2004) 1.21
Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome. Development (2012) 1.21
Delayed arteriogenesis in hypercholesterolemic mice. Circulation (2005) 1.19
Acceleration of cardiovascular disease by a dysfunctional prostacyclin receptor mutation: potential implications for cyclooxygenase-2 inhibition. Circ Res (2008) 1.17
Transcriptional profiling in coronary artery disease: indications for novel markers of coronary collateralization. Circulation (2006) 1.17
Expression of VEGF and angiopoietins-1 and -2 during ischemia-induced coronary angiogenesis. Am J Physiol Heart Circ Physiol (2003) 1.16
Arteriogenesis: noninvasive quantification with multi-detector row CT angiography and three-dimensional volume rendering in rodents. Radiology (2006) 1.16
Phosphorylation of VE-cadherin controls endothelial phenotypes via p120-catenin coupling and Rac1 activation. Am J Physiol Heart Circ Physiol (2010) 1.15
Humoral and cellular factors responsible for coronary collateral formation. Am J Cardiol (2006) 1.14
Copper chelation represses the vascular response to injury. Proc Natl Acad Sci U S A (2003) 1.13
The diaphragms of fenestrated endothelia: gatekeepers of vascular permeability and blood composition. Dev Cell (2012) 1.13
High-resolution quantitative computed tomography demonstrating selective enhancement of medium-size collaterals by placental growth factor-1 in the mouse ischemic hindlimb. Circulation (2006) 1.13
Abnormalities in the regulators of angiogenesis in patients with scleroderma. J Rheumatol (2009) 1.10
Micro computed tomography for vascular exploration. J Angiogenes Res (2010) 1.09
Angiogenesis, arteriogenesis, and diabetes: paradigm reassessed? J Am Coll Cardiol (2005) 1.09
Cell communications in the heart. Circulation (2010) 1.09
VEGF-B-induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart. EMBO Mol Med (2014) 1.08
Transmission disequilibrium of polymorphic variants in the tryptophan hydroxylase-2 gene in children and adolescents with obsessive-compulsive disorder. Int J Neuropsychopharmacol (2005) 1.08
Dll4-Notch signaling determines the formation of native arterial collateral networks and arterial function in mouse ischemia models. Development (2013) 1.07
The antiangiogenic activity of rPAI-1(23) inhibits vasa vasorum and growth of atherosclerotic plaque. Circ Res (2009) 1.07
Proline- and arginine-rich peptides constitute a novel class of allosteric inhibitors of proteasome activity. Biochemistry (2003) 1.07
Endothelial-to-mesenchymal transition drives atherosclerosis progression. J Clin Invest (2015) 1.06
Endothelial nuclear factor-κB-dependent regulation of arteriogenesis and branching. Circulation (2012) 1.06
Insights from angiogenesis trials using fibroblast growth factor for advanced arteriosclerotic disease. Trends Cardiovasc Med (2003) 1.06
Protein kinase C (PKC) delta regulates PKCalpha activity in a Syndecan-4-dependent manner. J Biol Chem (2002) 1.06
The heparan sulfate motif (GlcNS6S-IdoA2S)3, common in heparin, has a strict topography and is involved in cell behavior and disease. J Biol Chem (2010) 1.03
Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties. Cancer Cell (2013) 1.01
Growth factor-induced therapeutic angiogenesis in the heart: protein therapy. Cardiovasc Res (2005) 1.01
Cleavage of syndecan-4 by ADAMTS1 provokes defects in adhesion. Int J Biochem Cell Biol (2008) 1.01
Syndecan-4 signaling at a glance. J Cell Sci (2013) 1.01
Endothelial cell-dependent regulation of arteriogenesis. Circ Res (2013) 1.00
Synectin/syndecan-4 regulate coronary arteriolar growth during development. Dev Dyn (2007) 1.00
Syndecan-4 mediates macrophage uptake of group V secretory phospholipase A2-modified LDL. J Lipid Res (2008) 0.99
NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth. J Clin Invest (2013) 0.99
Angiogenesis in the human heart: gene and cell therapy. Angiogenesis (2005) 0.97
Targeting GIPC/synectin in pancreatic cancer inhibits tumor growth. Clin Cancer Res (2009) 0.96
System development for high frequency ultrasound-guided fluorescence quantification of skin layers. J Biomed Opt (2010) 0.96
Long-term effects of surgical angiogenic therapy with fibroblast growth factor 2 protein. J Thorac Cardiovasc Surg (2002) 0.95
Effects of cell grafting on coronary remodeling after myocardial infarction. J Am Heart Assoc (2013) 0.95
Transmembrane protein ESDN promotes endothelial VEGF signaling and regulates angiogenesis. J Clin Invest (2013) 0.95
Angiopoietin-2 secretion by endothelial cell exosomes: regulation by the phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) and syndecan-4/syntenin pathways. J Biol Chem (2013) 0.95
State-of-the-Art Methods for Evaluation of Angiogenesis and Tissue Vascularization: A Scientific Statement From the American Heart Association. Circ Res (2015) 0.94
Syndecan 4 regulates FGFR1 signaling in endothelial cells by directing macropinocytosis. Sci Signal (2012) 0.94
Antiangiogenic plasma activity in patients with systemic sclerosis. Arthritis Rheum (2007) 0.94
Inherent and benzo[a]pyrene-induced differential aryl hydrocarbon receptor signaling greatly affects life span, atherosclerosis, cardiac gene expression, and body and heart growth in mice. Toxicol Sci (2012) 0.94
The principal neuronal gD-type 3-O-sulfotransferases and their products in central and peripheral nervous system tissues. Matrix Biol (2007) 0.93
Adenoviral PR39 improves blood flow and myocardial function in a pig model of chronic myocardial ischemia by enhancing collateral formation. Am J Physiol Regul Integr Comp Physiol (2005) 0.93
Syndecan-4 modulates basic fibroblast growth factor 2 signaling in vivo. Am J Physiol Heart Circ Physiol (2003) 0.93
Molecular basis for proline- and arginine-rich peptide inhibition of proteasome. J Mol Biol (2008) 0.92
Regulation of vascular integrity. J Mol Med (Berl) (2009) 0.92
Endothelial RAF1/ERK activation regulates arterial morphogenesis. Blood (2013) 0.92
Synectin-dependent gene expression in endothelial cells. Physiol Genomics (2006) 0.92
FRS2 via fibroblast growth factor receptor 1 is required for platelet-derived growth factor receptor beta-mediated regulation of vascular smooth muscle marker gene expression. J Biol Chem (2009) 0.92
PR39 inhibits apoptosis in hypoxic endothelial cells: role of inhibitor apoptosis protein-2. Circulation (2004) 0.92
Human follicular fluid heparan sulfate contains abundant 3-O-sulfated chains with anticoagulant activity. J Biol Chem (2008) 0.91
Spatial heterogeneity in VEGF-induced vasodilation: VEGF dilates microvessels but not epicardial and systemic arteries and veins. Ann Vasc Surg (2003) 0.90
Synthesis of anticoagulantly active heparan sulfate proteoglycans by glomerular epithelial cells involves multiple 3-O-sulfotransferase isoforms and a limiting precursor pool. J Biol Chem (2005) 0.90
Retracted Protection against myocardial ischemia-reperfusion injury by the angiogenic Masterswitch protein PR 39 gene therapy: the roles of HIF1alpha stabilization and FGFR1 signaling. Antioxid Redox Signal (2007) 0.90
VEGF and restenosis: the rest of the story. Arterioscler Thromb Vasc Biol (2009) 0.90
The anti-angiogenic activity of rPAI-1(23) inhibits fibroblast growth factor-2 functions. J Biol Chem (2006) 0.89
Live 3D echo guidance of catheter-based endomyocardial injection. Catheter Cardiovasc Interv (2005) 0.89
Obesity is mediated by differential aryl hydrocarbon receptor signaling in mice fed a Western diet. Environ Health Perspect (2012) 0.88