Published in J Neurosci on May 01, 2002
Optogenetic and potassium channel gene therapy in a rodent model of focal neocortical epilepsy. Sci Transl Med (2012) 3.53
Progressive dendritic HCN channelopathy during epileptogenesis in the rat pilocarpine model of epilepsy. J Neurosci (2007) 2.34
Silencing of the Cav3.2 T-type calcium channel gene in sensory neurons demonstrates its major role in nociception. EMBO J (2004) 2.15
Massive and specific dysregulation of direct cortical input to the hippocampus in temporal lobe epilepsy. J Neurosci (2006) 1.71
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Functional stabilization of weakened thalamic pacemaker channel regulation in rat absence epilepsy. J Physiol (2006) 1.15
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Ca(2+) signaling by T-type Ca(2+) channels in neurons. Pflugers Arch (2008) 1.07
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Ionic mechanism underlying recovery of rhythmic activity in adult isolated neurons. J Neurophysiol (2006) 1.06
Recruitment of apical dendritic T-type Ca2+ channels by backpropagating spikes underlies de novo intrinsic bursting in hippocampal epileptogenesis. J Physiol (2007) 1.05
Persistent sodium current drives conditional pacemaking in CA1 pyramidal neurons under muscarinic stimulation. J Neurosci (2013) 1.02
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Characterization of the gating brake in the I-II loop of CaV3 T-type calcium channels. Channels (Austin) (2010) 0.92
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The involvement of Cav3.2/alpha1H T-type calcium channels in excitability of mouse embryonic primary vestibular neurones. J Physiol (2005) 0.89
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A transitional period of Ca2+-dependent spike afterdepolarization and bursting in developing rat CA1 pyramidal cells. J Physiol (2005) 0.87
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Intrinsic Bursting Alone Does Not Beget Seizures. Epilepsy Curr (2003) 0.84
Zinc regulates a key transcriptional pathway for epileptogenesis via metal-regulatory transcription factor 1. Nat Commun (2015) 0.83
Epileptiform activities in slices of hippocampus from mice after intra-hippocampal injection of kainic acid. J Physiol (2008) 0.83
Z944, a Novel Selective T-Type Calcium Channel Antagonist Delays the Progression of Seizures in the Amygdala Kindling Model. PLoS One (2015) 0.83
Presynaptic inhibitory terminals are functionally abnormal in a rat model of posttraumatic epilepsy. J Neurophysiol (2010) 0.82
Altered expression and function of small-conductance (SK) Ca(2+)-activated K+ channels in pilocarpine-treated epileptic rats. Brain Res (2010) 0.82
ACTH induces Cav3.2 current and mRNA by cAMP-dependent and cAMP-independent mechanisms. J Biol Chem (2010) 0.82
Intrinsic neurophysiological properties of hilar ectopic and normotopic dentate granule cells in human temporal lobe epilepsy and a rat model. J Neurophysiol (2014) 0.81
Calcium channel dysfunction in inferior colliculus neurons of the genetically epilepsy-prone rat. Neuropharmacology (2008) 0.80
Blockade of the sodium calcium exchanger exhibits anticonvulsant activity in a pilocarpine model of acute seizures in rats. Brain Res (2010) 0.80
Altered expression of the voltage-gated calcium channel subunit α₂δ-1: a comparison between two experimental models of epilepsy and a sensory nerve ligation model of neuropathic pain. Neuroscience (2014) 0.79
Cortical up state activity is enhanced after seizures: a quantitative analysis. J Clin Neurophysiol (2010) 0.79
Zinc induces long-term upregulation of T-type calcium current in hippocampal neurons in vivo. J Physiol (2012) 0.79
Inorganic polyphosphate regulates neuronal excitability through modulation of voltage-gated channels. Mol Brain (2014) 0.79
Eslicarbazepine acetate for the treatment of focal epilepsy: an update on its proposed mechanisms of action. Pharmacol Res Perspect (2015) 0.78
Acute alterations of somatodendritic action potential dynamics in hippocampal CA1 pyramidal cells after kainate-induced status epilepticus in mice. PLoS One (2011) 0.77
A persistent little current with a big impact on epileptic firing. Epilepsy Curr (2011) 0.76
Effects of eslicarbazepine acetate on acute and chronic latrunculin A-induced seizures and extracellular amino acid levels in the mouse hippocampus. BMC Neurosci (2014) 0.76
Calcium currents burst back: a possible role for dendrites in epileptogenesis. Epilepsy Curr (2008) 0.76
Serotonin Regulates the Firing of Principal Cells of the Subiculum by Inhibiting a T-type Ca(2+) Current. Front Cell Neurosci (2017) 0.76
Homeostasis or channelopathy? Acquired cell type-specific ion channel changes in temporal lobe epilepsy and their antiepileptic potential. Front Physiol (2015) 0.75
T-channels: short-term up-regulation causes long-term consequences in epilepsy. Epilepsy Curr (2009) 0.75
Ps in the (channel) pod are not alike... Epilepsy Curr (2008) 0.75
Human infection with a novel avian-origin influenza A (H7N9) virus. N Engl J Med (2013) 24.88
Approaches to catheter ablation for persistent atrial fibrillation. N Engl J Med (2015) 6.68
Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice. Nat Immunol (2007) 6.67
The clinicopathologic spectrum of focal cortical dysplasias: a consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission. Epilepsia (2010) 6.23
Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model. Cancer Cell (2009) 4.82
TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment. Neuron (2008) 4.00
Pten haploinsufficiency accelerates formation of high-grade astrocytomas. Cancer Res (2008) 3.99
Acquired dendritic channelopathy in temporal lobe epilepsy. Science (2004) 3.85
The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor. Cell (2003) 3.36
EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation. Cancer Cell (2013) 3.13
High-performance thin-film transistors using semiconductor nanowires and nanoribbons. Nature (2003) 3.01
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. Genome Res (2003) 2.91
Amplicon melting analysis with labeled primers: a closed-tube method for differentiating homozygotes and heterozygotes. Clin Chem (2003) 2.91
Essential and overlapping functions for mammalian Argonautes in microRNA silencing. Genes Dev (2009) 2.73
Why mothers stop breastfeeding: mothers' self-reported reasons for stopping during the first year. Pediatrics (2008) 2.68
Novel reassortant highly pathogenic H5N2 avian influenza viruses in poultry in China. PLoS One (2012) 2.43
Cerebral white matter lesions, gait, and the risk of incident falls: a prospective population-based study. Stroke (2008) 2.32
KCNQ/M channels control spike afterdepolarization and burst generation in hippocampal neurons. J Neurosci (2004) 2.20
High operative risk of cool-tip radiofrequency ablation for unresectable pancreatic head cancer. J Surg Oncol (2006) 2.19
The insulin-regulated CREB coactivator TORC promotes stress resistance in Drosophila. Cell Metab (2008) 2.09
Infant Feeding Practices Study II: study methods. Pediatrics (2008) 2.05
The neuronal transporter gene SLC6A15 confers risk to major depression. Neuron (2011) 2.02
Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A. Brain (2013) 1.95
Enhanced expression of a specific hyperpolarization-activated cyclic nucleotide-gated cation channel (HCN) in surviving dentate gyrus granule cells of human and experimental epileptic hippocampus. J Neurosci (2003) 1.94
Plasticity of intrinsic neuronal properties in CNS disorders. Nat Rev Neurosci (2008) 1.84
Activity-dependent control of neuronal output by local and global dendritic spike attenuation. Neuron (2009) 1.81
A new clinico-pathological classification system for mesial temporal sclerosis. Acta Neuropathol (2007) 1.77
A genome-wide association study in Han Chinese identifies multiple susceptibility loci for IgA nephropathy. Nat Genet (2011) 1.77
Functional specialization of presynaptic Cav2.3 Ca2+ channels. Neuron (2003) 1.77
Role of axonal NaV1.6 sodium channels in action potential initiation of CA1 pyramidal neurons. J Neurophysiol (2008) 1.76
High-throughput mapping of origins of replication in human cells. EMBO Rep (2007) 1.75
A novel software platform for medical image processing and analyzing. IEEE Trans Inf Technol Biomed (2008) 1.72
Brain atrophy in type 2 diabetes: regional distribution and influence on cognition. Diabetes Care (2013) 1.71
EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer. BMC Cancer (2012) 1.70
Aurora B kinase phosphorylates and instigates degradation of p53. Proc Natl Acad Sci U S A (2012) 1.66
Frequent recurrence and progression in pilocytic astrocytoma in adults. Cancer (2007) 1.62
Functional integration of embryonic stem cell-derived neurons in vivo. J Neurosci (2004) 1.62
PTEN regulates collagen-induced platelet activation. Blood (2010) 1.60
Molecular and cellular mechanisms of pharmacoresistance in epilepsy. Brain (2005) 1.59
Enhancing collaborative filtering by user interest expansion via personalized ranking. IEEE Trans Syst Man Cybern B Cybern (2011) 1.58
Identification of acyl coenzyme A:monoacylglycerol acyltransferase 3, an intestinal specific enzyme implicated in dietary fat absorption. J Biol Chem (2003) 1.57
MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity. Brain Res (2010) 1.56
Inhibitory control of linear and supralinear dendritic excitation in CA1 pyramidal neurons. Neuron (2012) 1.56
Transcriptional upregulation of Cav3.2 mediates epileptogenesis in the pilocarpine model of epilepsy. J Neurosci (2008) 1.54
Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers. J Clin Invest (2011) 1.54
CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors. Cell (2013) 1.53
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Hypoxia induces adhesion molecules on cancer cells: A missing link between Warburg effect and induction of selectin-ligand carbohydrates. Proc Natl Acad Sci U S A (2004) 1.50
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. Science (2011) 1.49
The Th17/Treg functional imbalance during atherogenesis in ApoE(-/-) mice. Cytokine (2009) 1.48
Left-behind children in rural China experience higher levels of anxiety and poorer living conditions. Acta Paediatr (2014) 1.47
Changes of soil organic carbon in an intensively cultivated agricultural region: a denitrification-decomposition (DNDC) modelling approach. Sci Total Environ (2006) 1.45
Expression cloning of functional receptor used by SARS coronavirus. Biochem Biophys Res Commun (2004) 1.44
Incidence and significance of early recurrences associated with different ablation strategies for AF: a STAR-AF substudy. J Cardiovasc Electrophysiol (2012) 1.44
Axo-somatic and apical dendritic Kv7/M channels differentially regulate the intrinsic excitability of adult rat CA1 pyramidal cells. J Neurophysiol (2006) 1.44
Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein. Acta Neuropathol (2013) 1.43
Impaired synaptic plasticity in a rat model of tuberous sclerosis. Eur J Neurosci (2006) 1.42
A novel mechanism underlying drug resistance in chronic epilepsy. Ann Neurol (2003) 1.41
Controlled assembly of carbon nanotubes by designed amphiphilic Peptide helices. J Am Chem Soc (2003) 1.40
gamma-Cyclodextrin: a review on enzymatic production and applications. Appl Microbiol Biotechnol (2007) 1.39
Flexible solid-state supercapacitors based on carbon nanoparticles/MnO2 nanorods hybrid structure. ACS Nano (2011) 1.39
Therapeutic potential of mesenchymal stem cells producing interferon-alpha in a mouse melanoma lung metastasis model. Stem Cells (2008) 1.38
Expression and characterization of human transient receptor potential melastatin 3 (hTRPM3). J Biol Chem (2003) 1.37
Inositol hexakisphosphate mobilizes an endomembrane store of calcium in guard cells. Proc Natl Acad Sci U S A (2003) 1.37
Application of minimally invasive treatment for early gastric cancer. J Surg Oncol (2004) 1.37
Dendritic integration in hippocampal dentate granule cells. Neuron (2011) 1.36
h channel-dependent deficit of theta oscillation resonance and phase shift in temporal lobe epilepsy. Neurobiol Dis (2008) 1.35
CD8+ T-cell clones dominate brain infiltrates in Rasmussen encephalitis and persist in the periphery. Brain (2009) 1.33
Immune-deficient Drosophila melanogaster: a model for the innate immune response to human fungal pathogens. J Immunol (2004) 1.33
Functional integration of embryonic stem cell-derived neurons in hippocampal slice cultures. J Neurosci (2003) 1.32
New advances in plant growth-promoting rhizobacteria for bioremediation. Environ Int (2007) 1.31
Overexpression of activation-induced cytidine deaminase in B cells is associated with production of highly pathogenic autoantibodies. J Immunol (2007) 1.30
Proximal persistent Na+ channels drive spike afterdepolarizations and associated bursting in adult CA1 pyramidal cells. J Neurosci (2005) 1.30
Expression of an Arabidopsis vacuolar H+-pyrophosphatase gene (AVP1) in cotton improves drought- and salt tolerance and increases fibre yield in the field conditions. Plant Biotechnol J (2011) 1.30
Survival benefit of metastasectomy for Krukenberg tumors from gastric cancer. Gynecol Oncol (2004) 1.29
Temporally specified genetic ablation of neurogenesis impairs cognitive recovery after traumatic brain injury. J Neurosci (2011) 1.29
A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters. Cell Rep (2013) 1.28
Endogenous Ca2+ buffer concentration and Ca2+ microdomains in hippocampal neurons. J Neurosci (2005) 1.28
Isthmus characteristics of reentrant ventricular tachycardia after myocardial infarction. Circulation (2002) 1.27
Exploring off-targets and off-systems for adverse drug reactions via chemical-protein interactome--clozapine-induced agranulocytosis as a case study. PLoS Comput Biol (2011) 1.26
Substrate and Trigger Ablation for Reduction of Atrial Fibrillation (STAR AF): a randomized, multicentre, international trial. Eur Heart J (2010) 1.25
High performance, waveguide integrated Ge photodetectors. Opt Express (2007) 1.25
Quantifying the complexity of bat wing kinematics. J Theor Biol (2008) 1.24
Ion channels in genetic and acquired forms of epilepsy. J Physiol (2012) 1.24
DRAR-CPI: a server for identifying drug repositioning potential and adverse drug reactions via the chemical-protein interactome. Nucleic Acids Res (2011) 1.23
Glutathione: a review on biotechnological production. Appl Microbiol Biotechnol (2004) 1.22
An ultra-high density bin-map for rapid QTL mapping for tassel and ear architecture in a large F₂ maize population. BMC Genomics (2014) 1.22
Axon initial segment dysfunction in a mouse model of genetic epilepsy with febrile seizures plus. J Clin Invest (2010) 1.21
Highly infectious SARS-CoV pseudotyped virus reveals the cell tropism and its correlation with receptor expression. Biochem Biophys Res Commun (2004) 1.20
Qiliqiangxin regulates the balance between tumor necrosis factor-alpha and interleukin-10 and improves cardiac function in rats with myocardial infarction. Cell Immunol (2009) 1.19
CSF-1 receptor structure/function in MacCsf1r-/- macrophages: regulation of proliferation, differentiation, and morphology. J Leukoc Biol (2008) 1.19
Extensive, clustered parental imprinting of protein-coding and noncoding RNAs in developing maize endosperm. Proc Natl Acad Sci U S A (2011) 1.19
Menetrier's disease in korea: report of two cases and review of cases in a gastric cancer prevalent region. Yonsei Med J (2004) 1.18
High DcR3 expression predicts stage pN2 in gastric cancer. Hepatogastroenterology (2008) 1.18
Harvesting candidate genes responsible for serious adverse drug reactions from a chemical-protein interactome. PLoS Comput Biol (2009) 1.18