Published in Circ Res on May 03, 2002
Proteomic identification of 14-3-3zeta as a mitogen-activated protein kinase-activated protein kinase 2 substrate: role in dimer formation and ligand binding. Mol Cell Biol (2003) 1.53
Cyclin-dependent kinase 5 regulates endothelial cell migration and angiogenesis. J Biol Chem (2010) 1.35
ANP attenuates inflammatory signaling and Rho pathway of lung endothelial permeability induced by LPS and TNFalpha. Microvasc Res (2009) 1.18
Rac GTPase is a hub for protein kinase A and Epac signaling in endothelial barrier protection by cAMP. Microvasc Res (2009) 1.16
Atrial natriuretic peptide attenuates LPS-induced lung vascular leak: role of PAK1. Am J Physiol Lung Cell Mol Physiol (2010) 1.10
MK2 SUMOylation regulates actin filament remodeling and subsequent migration in endothelial cells by inhibiting MK2 kinase and HSP27 phosphorylation. Blood (2010) 1.00
APPL1 mediates adiponectin-stimulated p38 MAPK activation by scaffolding the TAK1-MKK3-p38 MAPK pathway. Am J Physiol Endocrinol Metab (2010) 1.00
Control of vascular permeability by atrial natriuretic peptide via a GEF-H1-dependent mechanism. J Biol Chem (2013) 0.93
Endothelial actions of atrial and B-type natriuretic peptides. Br J Pharmacol (2012) 0.92
Atrial natriuretic peptide protects against Staphylococcus aureus-induced lung injury and endothelial barrier dysfunction. J Appl Physiol (1985) (2010) 0.91
Microtubule stabilization opposes the (TNF-alpha)-induced loss in the barrier integrity of corneal endothelium. Exp Eye Res (2009) 0.91
Barrier dysfunction of the corneal endothelium in response to TNF-alpha: role of p38 MAP kinase. Invest Ophthalmol Vis Sci (2009) 0.88
Adenosine A1 receptors promote vasa vasorum endothelial cell barrier integrity via Gi and Akt-dependent actin cytoskeleton remodeling. PLoS One (2013) 0.87
Ischemia/reperfusion-induced MKP-3 impairs endothelial NO formation via inactivation of ERK1/2 pathway. PLoS One (2012) 0.85
Sphingosine-1-phosphate inhibits high glucose-mediated ERK1/2 action in endothelium through induction of MAP kinase phosphatase-3. Am J Physiol Cell Physiol (2008) 0.83
Stimulation of p38 MAPK by hormonal preconditioning with atrial natriuretic peptide. World J Gastroenterol (2002) 0.82
Cell-type-specific crosstalk between p38 MAPK and Rho signaling in lung micro- and macrovascular barrier dysfunction induced by Staphylococcus aureus-derived pathogens. Transl Res (2013) 0.81
Effects of atrial natriuretic peptide on inter-organ crosstalk among the kidney, lung, and heart in a rat model of renal ischemia-reperfusion injury. Intensive Care Med Exp (2014) 0.80
Reactive Oxygen Species, SUMOylation, and Endothelial Inflammation. Int J Inflam (2012) 0.80
Epigallocatechin gallate inhibits angiotensin II-induced endothelial barrier dysfunction via inhibition of the p38 MAPK/HSP27 pathway. Acta Pharmacol Sin (2010) 0.80
Opposite effects of ANP receptors in attenuation of LPS-induced endothelial permeability and lung injury. Microvasc Res (2011) 0.79
Acute alcohol intoxication-induced microvascular leakage. Alcohol Clin Exp Res (2014) 0.78
Endothelial permeability in vitro and in vivo: protective actions of ANP and omapatrilat in experimental atherosclerosis. Peptides (2013) 0.78
Endothelium-Derived 5-Methoxytryptophan Protects Endothelial Barrier Function by Blocking p38 MAPK Activation. PLoS One (2016) 0.78
Heparin Decreases in Tumor Necrosis Factor α (TNFα)-induced Endothelial Stress Responses Require Transmembrane Protein 184A and Induction of Dual Specificity Phosphatase 1. J Biol Chem (2016) 0.77
MAPK-activated protein kinase 2-deficiency causes hyperacute tumor necrosis factor-induced inflammatory shock. BMC Physiol (2014) 0.77
PI 3-kinase pathway is responsible for antiapoptotic effects of atrial natriuretic peptide in rat liver transplantation. World J Gastroenterol (2006) 0.76
Atrial natriuretic peptide down-regulates neutrophil recruitment on inflamed endothelium by reducing cell deformability and resistance to detachment force. Biorheology (2015) 0.76
The role of atrial natriuretic peptide to attenuate inflammation in a mouse skin wound and individually perfused rat mesenteric microvessels. Physiol Rep (2016) 0.75
Peroxisome proliferator-activated receptor γ is essential for secretion of ANP induced by prostaglandin D2 in the beating rat atrium. Korean J Physiol Pharmacol (2017) 0.75
Mitogen-activated protein kinase phosphatase 1 (MKP-1) in macrophage biology and cardiovascular disease. A redox-regulated master controller of monocyte function and macrophage phenotype. Free Radic Biol Med (2017) 0.75
Signaling pathways involved in renal oxidative injury: role of the vasoactive peptides and the renal dopaminergic system. J Signal Transduct (2014) 0.75
Natriuretic peptide receptor guanylyl cyclase-A pathway counteracts glomerular injury evoked by aldosterone through p38 mitogen-activated protein kinase inhibition. Sci Rep (2017) 0.75
Inhibition of cancer cell epithelial mesenchymal transition by normal fibroblasts via production of 5-methoxytryptophan. Oncotarget (2016) 0.75
Prostaglandin E receptor-4 receptor mediates endothelial barrier-enhancing and anti-inflammatory effects of oxidized phospholipids. FASEB J (2017) 0.75
Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone. Chem Sci (2017) 0.75
Helium induces preconditioning in human endothelium in vivo. Anesthesiology (2013) 2.03
Red wine polyphenols enhance endothelial nitric oxide synthase expression and subsequent nitric oxide release from endothelial cells. Circulation (2002) 1.77
Activation of endothelial nitric oxide synthase by red wine polyphenols: impact of grape cultivars, growing area and the vinification process. J Hypertens (2007) 1.56
Anti-inflammatory effects of a bioavailable compound, Artepillin C, in Brazilian propolis. Eur J Pharmacol (2008) 1.46
Atrial natriuretic peptide preconditioning protects against hepatic preservation injury by attenuating necrotic and apoptotic cell death. J Hepatol (2003) 1.45
Inhibitor of apoptosis proteins as novel targets in inflammatory processes. Arterioscler Thromb Vasc Biol (2011) 1.43
Cyclin-dependent kinase 5 regulates endothelial cell migration and angiogenesis. J Biol Chem (2010) 1.35
Evaluation of the analgesic and anti-inflammatory effects of a Brazilian green propolis. Planta Med (2006) 1.25
Silibinin protects mice from T cell-dependent liver injury. J Hepatol (2003) 1.23
Linkage analysis using sex-specific recombination fractions with GENEHUNTER-MODSCORE. Bioinformatics (2006) 1.21
Alpha-lipoic acid preconditioning reduces ischemia-reperfusion injury of the rat liver via the PI3-kinase/Akt pathway. Am J Physiol Gastrointest Liver Physiol (2003) 1.18
Helium-induced preconditioning in young and old rat heart: impact of mitochondrial Ca(2+) -sensitive potassium channel activation. Anesthesiology (2008) 1.14
Atrial natriuretic peptide induces mitogen-activated protein kinase phosphatase-1 in human endothelial cells via Rac1 and NAD(P)H oxidase/Nox2-activation. Circ Res (2004) 1.14
MAPK phosphatase-1 represents a novel anti-inflammatory target of glucocorticoids in the human endothelium. FASEB J (2006) 1.12
Mode of cell death induction by pharmacological vacuolar H+-ATPase (V-ATPase) inhibition. J Biol Chem (2012) 1.08
The V-ATPase-inhibitor archazolid abrogates tumor metastasis via inhibition of endocytic activation of the Rho-GTPase Rac1. Cancer Res (2012) 1.08
Resveratrol suppresses angiotensin II-induced Akt/protein kinase B and p70 S6 kinase phosphorylation and subsequent hypertrophy in rat aortic smooth muscle cells. Mol Pharmacol (2002) 1.07
Twice switched at birth: cell cycle-independent roles of the "neuron-specific" cyclin-dependent kinase 5 (Cdk5) in non-neuronal cells. Cell Signal (2011) 1.06
Molecular mechanisms transducing the anesthetic, analgesic, and organ-protective actions of xenon. Anesthesiology (2006) 1.05
Cephalostatin 1 selectively triggers the release of Smac/DIABLO and subsequent apoptosis that is characterized by an increased density of the mitochondrial matrix. Cancer Res (2003) 1.05
Perspective of cyclin-dependent kinase 9 (CDK9) as a drug target. Curr Pharm Des (2012) 1.04
Flavopiridol protects against inflammation by attenuating leukocyte-endothelial interaction via inhibition of cyclin-dependent kinase 9. Arterioscler Thromb Vasc Biol (2010) 1.03
Electrophoretic analysis of the mitochondrial outer membrane rupture induced by permeability transition. Anal Chem (2008) 0.99
Atrial natriuretic peptide, a regulator of nuclear factor-kappaB activation in vivo. Endocrinology (2006) 0.99
Inverse in silico screening for identification of kinase inhibitor targets. Chem Biol (2007) 0.98
The marine product cephalostatin 1 activates an endoplasmic reticulum stress-specific and apoptosome-independent apoptotic signaling pathway. J Biol Chem (2006) 0.98
Cephalostatin 1 inactivates Bcl-2 by hyperphosphorylation independent of M-phase arrest and DNA damage. Mol Pharmacol (2005) 0.97
Phyllanthus amarus has anti-inflammatory potential by inhibition of iNOS, COX-2, and cytokines via the NF-kappaB pathway. J Hepatol (2003) 0.96
Garlic (Allium sativum L.) modulates cytokine expression in lipopolysaccharide-activated human blood thereby inhibiting NF-kappaB activity. J Nutr (2003) 0.96
Targeting apoptosis pathways by natural compounds in cancer: marine compounds as lead structures and chemical tools for cancer therapy. Cancer Lett (2010) 0.95
Characterization of heme oxygenase 1 (heat shock protein 32) induction by atrial natriuretic peptide in human endothelial cells. Endocrinology (2003) 0.95
The cephalostatin way of apoptosis. J Nat Prod (2008) 0.95
The opioid peptides enkephalin and beta-endorphin in alcohol dependence. Biol Psychiatry (2008) 0.95
The contribution of the capillary endothelium to blood clearance and tissue deposition of anionic quantum dots in vivo. Biomaterials (2010) 0.94
Neurokinin-1 receptor antagonists CP-96,345 and L-733,060 protect mice from cytokine-mediated liver injury. J Pharmacol Exp Ther (2003) 0.94
Leoligin, the major lignan from Edelweiss, inhibits intimal hyperplasia of venous bypass grafts. Cardiovasc Res (2009) 0.93
Hypoxia-inducible factor 1 and related gene products in anaesthetic-induced preconditioning. Eur J Anaesthesiol (2009) 0.92
Impact of preconditioning protocol on anesthetic-induced cardioprotection in patients having coronary artery bypass surgery. J Thorac Cardiovasc Surg (2009) 0.92
Desflurane preconditioning induces time-dependent activation of protein kinase C epsilon and extracellular signal-regulated kinase 1 and 2 in the rat heart in vivo. Anesthesiology (2004) 0.92
Linkage analysis of alcohol dependence using MOD scores. BMC Genet (2005) 0.92
Protein kinase A dependent signalling mediates anti-apoptotic effects of the atrial natriuretic peptide in ischemic livers. J Hepatol (2004) 0.92
Metalloporphyrins inactivate caspase-3 and -8. FASEB J (2005) 0.92
Cellular effects of helium in different organs. Anesthesiology (2010) 0.92
Alpha-lipoic acid as a directly binding activator of the insulin receptor: protection from hepatocyte apoptosis. Biochemistry (2007) 0.91
Resveratrol inhibits angiotensin II- and epidermal growth factor-mediated Akt activation: role of Gab1 and Shp2. Mol Pharmacol (2005) 0.91
Inhibition of LPS-induced nitric oxide and TNF-alpha production by alpha-lipoic acid in rat Kupffer cells and in RAW 264.7 murine macrophages. Immunol Cell Biol (2002) 0.91
Hydrogen sulfide donor NaHS reduces organ injury in a rat model of pneumococcal pneumosepsis, associated with improved bio-energetic status. PLoS One (2013) 0.90
Trisubstituted pyrazolopyrimidines as novel angiogenesis inhibitors. PLoS One (2013) 0.90
The atrial natriuretic peptide and cGMP: novel activators of the heat shock response in rat livers. Hepatology (2002) 0.89
Roscovitine blocks leukocyte extravasation by inhibition of cyclin-dependent kinases 5 and 9. Br J Pharmacol (2011) 0.89
A novel approach to prevent endothelial hyperpermeability: the Crataegus extract WS® 1442 targets the cAMP/Rap1 pathway. J Mol Cell Cardiol (2011) 0.89
Synthetic cryptolepine inhibits DNA binding of NF-kappaB. Bioorg Med Chem (2006) 0.88
BH3-only proteins Mcl-1 and Bim as well as endonuclease G are targeted in spongistatin 1-induced apoptosis in breast cancer cells. Mol Cancer Ther (2009) 0.88
Anti-angiogenic effects of purine inhibitors of cyclin dependent kinases. Angiogenesis (2011) 0.88
The soy isoflavone genistein induces a late but sustained activation of the endothelial nitric oxide-synthase system in vitro. Br J Pharmacol (2005) 0.88
V-ATPase inhibition by archazolid leads to lysosomal dysfunction resulting in impaired cathepsin B activation in vivo. Int J Cancer (2013) 0.87
V-ATPase inhibition regulates anoikis resistance and metastasis of cancer cells. Mol Cancer Ther (2014) 0.87
Helium-induced cardioprotection of healthy and hypertensive rat myocardium in vivo. Eur J Pharmacol (2012) 0.87
Morphine induces late cardioprotection in rat hearts in vivo: the involvement of opioid receptors and nuclear transcription factor kappaB. Anesth Analg (2005) 0.87
Indirubin derivative 6BIO suppresses metastasis. Cancer Res (2013) 0.87
Age-related loss of cardiac preconditioning: impact of protein kinase A. Exp Gerontol (2011) 0.86
Caffeic acid phenethyl ester inhibits PDGF-induced proliferation of vascular smooth muscle cells via activation of p38 MAPK, HIF-1α, and heme oxygenase-1. J Nat Prod (2011) 0.86
In vivo regulation of inducible no synthase in immune-mediated liver injury in mice. Hepatology (2002) 0.86
Sevoflurane-induced preconditioning: impact of protocol and aprotinin administration on infarct size and endothelial nitric-oxide synthase phosphorylation in the rat heart in vivo. Anesthesiology (2010) 0.85
Resveratrol increases serine15-phosphorylated but transcriptionally impaired p53 and induces a reversible DNA replication block in serum-activated vascular smooth muscle cells. Mol Pharmacol (2003) 0.85
Anti-angiogenic potential of small molecular inhibitors of cyclin dependent kinases in vitro. Angiogenesis (2010) 0.85
ANP inhibits TNF-alpha-induced endothelial MCP-1 expression--involvement of p38 MAPK and MKP-1. J Leukoc Biol (2003) 0.85
Investigation of the marine compound spongistatin 1 links the inhibition of PKCalpha translocation to nonmitotic effects of tubulin antagonism in angiogenesis. FASEB J (2008) 0.84
Ginkgo biloba extract EGb 761 exerts anti-angiogenic effects via activation of tyrosine phosphatases. J Cell Mol Med (2008) 0.84
Postconditioning by xenon and hypothermia in the rat heart in vivo. Eur J Anaesthesiol (2010) 0.84
Hypoxia induces late preconditioning in the rat heart in vivo. Anesthesiology (2010) 0.83
Vasoprotective actions of the atrial natriuretic peptide. Curr Med Chem Cardiovasc Hematol Agents (2005) 0.83
Short-term activation induces multifunctional dendritic cells that generate potent antitumor T-cell responses in vivo. Cancer Immunol Immunother (2008) 0.83
Hepatocyte cytoskeleton during ischemia and reperfusion--influence of ANP-mediated p38 MAPK activation. World J Gastroenterol (2005) 0.83
The marine compound spongistatin 1 targets pancreatic tumor progression and metastasis. Int J Cancer (2010) 0.83
Apoptosis signaling triggered by the marine alkaloid ascididemin is routed via caspase-2 and JNK to mitochondria. Oncogene (2004) 0.82
Neoandrographolide from Andrographis paniculata as a potential natural chemosensitizer. Planta Med (2010) 0.82
The atrial natriuretic peptide as a regulator of Kupffer cell functions. Shock (2002) 0.82
Kupffer-cell specific induction of heme oxygenase 1 (hsp32) by the atrial natriuretic peptide--role of cGMP. J Hepatol (2003) 0.82
Noble gases as cardioprotectants - translatability and mechanism. Br J Pharmacol (2015) 0.82
Stimulation of p38 MAPK by hormonal preconditioning with atrial natriuretic peptide. World J Gastroenterol (2002) 0.82
Pretubulysin: from hypothetical biosynthetic intermediate to potential lead in tumor therapy. PLoS One (2012) 0.82