Published in Chem Res Toxicol on May 01, 2002
Cigarette smoking: cancer risks, carcinogens, and mechanisms. Langenbecks Arch Surg (2006) 1.67
Cross-species analysis of nicotine-induced proteomic alterations in pancreatic cells. Proteomics (2013) 1.42
Genetic mutations associated with cigarette smoking in pancreatic cancer. Cancer Res (2009) 1.28
Lipid-soluble components in cigarette smoke induce mitochondrial production of reactive oxygen species in lung epithelial cells. Am J Physiol Lung Cell Mol Physiol (2009) 1.16
A prospective study of Helicobacter pylori in relation to the risk for pancreatic cancer. BMC Cancer (2008) 1.07
Analysis of pyridyloxobutyl and pyridylhydroxybutyl DNA adducts in extrahepatic tissues of F344 rats treated chronically with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol. Chem Res Toxicol (2009) 0.99
The emerging role of smoking in the development of pancreatitis. Pancreatology (2011) 0.97
Cigarette smoke-induced pancreatic damage: experimental data. Langenbecks Arch Surg (2008) 0.93
Detection of 2-amino-1-methyl-6-phenylimidazo [4,5-b]-pyridine (PhIP)-DNA adducts in human pancreatic tissues. Biomarkers (2006) 0.93
Global Analysis of Protein Expression and Phosphorylation Levels in Nicotine-Treated Pancreatic Stellate Cells. J Proteome Res (2015) 0.91
The burning question: why is smoking a risk factor for pancreatic cancer? Pancreatology (2012) 0.89
Pancreatic cancer patients who smoke and drink are diagnosed at younger ages. Clin Gastroenterol Hepatol (2009) 0.88
Smoking and other personal characteristics as potential predictors for fecal bacteria populations in humans. Med Sci Monit (2010) 0.86
Tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone initiates and enhances pancreatitis responses. Am J Physiol Gastrointest Liver Physiol (2012) 0.83
Effect of the cigarette smoke component, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), on physiological and molecular parameters of thiamin uptake by pancreatic acinar cells. PLoS One (2013) 0.83
The pathobiological impact of cigarette smoke on pancreatic cancer development (review). Int J Oncol (2012) 0.82
Interplay between smoking-induced genotoxicity and altered signaling in pancreatic carcinogenesis. Carcinogenesis (2012) 0.81
Effects of tobacco constituents and psychological stress on the beta-adrenergic regulation of non-small cell lung cancer and pancreatic cancer: implications for intervention. Cancer Biomark (2013) 0.81
Elucidating Organ-Specific Metabolic Toxicity Chemistry from Electrochemiluminescent Enzyme/DNA Arrays and Bioreactor Bead-LC-MS/MS. Chem Sci (2015) 0.81
The tobacco carcinogen NNK is stereoselectively reduced by human pancreatic microsomes and cytosols. Langenbecks Arch Surg (2008) 0.78
Liquid chromatography-electrospray ionization-tandem mass spectrometry quantitation of urinary [pyridine-D4]4-hydroxy-4-(3-pyridyl)butanoic acid, a biomarker of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolic activation in smokers. Chem Res Toxicol (2014) 0.78
Chronic Nicotine Exposure In Vivo and In Vitro Inhibits Vitamin B1 (Thiamin) Uptake by Pancreatic Acinar Cells. PLoS One (2015) 0.78
Akt kinase mediates the prosurvival effect of smoking compounds in pancreatic ductal cells. Pancreas (2013) 0.78
Nicotine alters the proteome of two human pancreatic duct cell lines. JOP (2014) 0.78
Pathologic cellular events in smoking-related pancreatitis. Cancers (Basel) (2015) 0.77
A geographic correlation study of the incidence of pancreatic and other cancers in Whites. Eur J Epidemiol (2006) 0.77
The role of tobacco-derived carcinogens in pancreas cancer. ISRN Oncol (2011) 0.77
Selective expression of CYP2A13 in human pancreatic α-islet cells. Drug Metab Dispos (2012) 0.76
Nicotine-induced protein expression profiling reveals mutually altered proteins across four human cell lines. Proteomics (2016) 0.76
Inhibition of pancreatic acinar mitochondrial thiamin pyrophosphate uptake by the cigarette smoke component 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Am J Physiol Gastrointest Liver Physiol (2016) 0.75
Prophylactic antibiotic treatment in patients with predicted severe acute pancreatitis: a placebo-controlled, double-blind trial. Gastroenterology (2004) 4.24
Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells. Gastroenterology (2005) 3.18
Impact of psychotherapeutic support for patients with gastrointestinal cancer undergoing surgery: 10-year survival results of a randomized trial. J Clin Oncol (2007) 2.98
Claudin-4 expression decreases invasiveness and metastatic potential of pancreatic cancer. Cancer Res (2003) 2.08
Minimal access kidney transplant: a novel technique to reduce surgical tissue trauma. Exp Clin Transplant (2012) 2.02
Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice. Cancer Res (2005) 1.94
Investigating the behavioral and self-report constructs of impulsivity domains using principal component analysis. Behav Pharmacol (2009) 1.90
The antidepressant effect of ketamine is not associated with changes in occipital amino acid neurotransmitter content as measured by [(1)H]-MRS. Psychiatry Res (2011) 1.80
Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis. J Biol Chem (2012) 1.79
Normalizing effects of modafinil on sleep in chronic cocaine users. Am J Psychiatry (2010) 1.73
Evaluation of procalcitonin for predicting septic multiorgan failure and overall prognosis in secondary peritonitis: a prospective, international multicenter study. Arch Surg (2007) 1.69
Sulforaphane inhibits prostate carcinogenesis and pulmonary metastasis in TRAMP mice in association with increased cytotoxicity of natural killer cells. Cancer Res (2009) 1.63
trans-Lesion synthesis past bulky benzo[a]pyrene diol epoxide N2-dG and N6-dA lesions catalyzed by DNA bypass polymerases. J Biol Chem (2002) 1.60
Esophageal perforation: principles of diagnosis and surgical management. Surg Today (2006) 1.60
Transcranial magnetic stimulation of Wernicke's and Right homologous sites to curtail "voices": a randomized trial. Biol Psychiatry (2013) 1.57
Targeting mitogen-activated protein kinase/extracellular signal-regulated kinase kinase in the mutant (V600E) B-Raf signaling cascade effectively inhibits melanoma lung metastases. Cancer Res (2006) 1.56
CD34 expression by hair follicle stem cells is required for skin tumor development in mice. Cancer Res (2007) 1.55
Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease. J Clin Invest (2014) 1.55
Severe acute pancreatitis: Clinical course and management. World J Gastroenterol (2007) 1.55
Discovery of marinopyrrole A (maritoclax) as a selective Mcl-1 antagonist that overcomes ABT-737 resistance by binding to and targeting Mcl-1 for proteasomal degradation. J Biol Chem (2012) 1.53
Parathyroidectomy, elevated depression scores, and suicidal ideation in patients with primary hyperparathyroidism: results of a prospective multicenter study. JAMA Surg (2013) 1.53
Glucuronidation of active tamoxifen metabolites by the human UDP glucuronosyltransferases. Drug Metab Dispos (2007) 1.48
Onset and exacerbation of obsessive-compulsive disorder in pregnancy and the postpartum period. J Clin Psychiatry (2010) 1.47
Preliminary evidence for persistent abnormalities in amygdala volumes in adolescents and young adults with bipolar disorder. Bipolar Disord (2005) 1.47
Treatment of pancreatic cancer: challenge of the facts. World J Surg (2003) 1.45
The major lipid peroxidation product, trans-4-hydroxy-2-nonenal, preferentially forms DNA adducts at codon 249 of human p53 gene, a unique mutational hotspot in hepatocellular carcinoma. Carcinogenesis (2002) 1.43
Family history of alcoholism influences naltrexone-induced reduction in alcohol drinking. Biol Psychiatry (2007) 1.42
Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expression levels: predictors for survival in colorectal cancer patients receiving adjuvant 5-fluorouracil. Clin Cancer Res (2003) 1.40
Regression of mouse prostatic intraepithelial neoplasia by nonsteroidal anti-inflammatory drugs in the transgenic adenocarcinoma mouse prostate model. Clin Cancer Res (2004) 1.37
Functional connectivity between ventral prefrontal cortex and amygdala at low frequency in the resting state in bipolar disorder. Psychiatry Res (2010) 1.35
Characteristics of infection with Candida species in patients with necrotizing pancreatitis. World J Surg (2001) 1.33
Relation between amygdala structure and function in adolescents with bipolar disorder. J Am Acad Child Adolesc Psychiatry (2009) 1.33
The uremic toxin 3-indoxyl sulfate is a potent endogenous agonist for the human aryl hydrocarbon receptor. Biochemistry (2010) 1.32
Elevated functional connectivity along a corticostriatal loop and the mechanism of auditory/verbal hallucinations in patients with schizophrenia. Biol Psychiatry (2010) 1.29
Sepsis induced changes of adipokines and cytokines - septic patients compared to morbidly obese patients. BMC Surg (2010) 1.28
Abnormal corpus callosum integrity in bipolar disorder: a diffusion tensor imaging study. Biol Psychiatry (2008) 1.24
Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands do not potentiate growth of human cancer cell lines. Carcinogenesis (2007) 1.23
Therapeutic application of caspase 1/interleukin-1beta-converting enzyme inhibitor decreases the death rate in severe acute experimental pancreatitis. Ann Surg (2002) 1.23
Targeting Akt3 signaling in malignant melanoma using isoselenocyanates. Clin Cancer Res (2009) 1.22
Frequency, symptoms and outcome of intestinal metastases of bronchopulmonary cancer. Case report and review of the literature. Int Semin Surg Oncol (2005) 1.19
H2S concentrations in the arterial blood during H2S administration in relation to its toxicity and effects on breathing. Am J Physiol Regul Integr Comp Physiol (2013) 1.19
Evidence for ligand-mediated selective modulation of aryl hydrocarbon receptor activity. Mol Pharmacol (2009) 1.18
Smokeless tobacco: a gateway to smoking or a way away from smoking. Biomarkers (2009) 1.18
Effect of memantine on cue-induced alcohol craving in recovering alcohol-dependent patients. Am J Psychiatry (2007) 1.17
Mutational spectrum and genotoxicity of the major lipid peroxidation product, trans-4-hydroxy-2-nonenal, induced DNA adducts in nucleotide excision repair-proficient and -deficient human cells. Biochemistry (2003) 1.16
Extracting spurious messages from noise and risk of schizophrenia-spectrum disorders in a prodromal population. Br J Psychiatry (2007) 1.16
Glucuronidation of PhIP and N-OH-PhIP by UDP-glucuronosyltransferase 1A10. Carcinogenesis (2007) 1.16
Cellular responses to cancer chemopreventive agent D,L-sulforaphane in human prostate cancer cells are initiated by mitochondrial reactive oxygen species. Pharm Res (2009) 1.14
New insights into the efficacy of naltrexone based on trajectory-based reanalyses of two negative clinical trials. Biol Psychiatry (2007) 1.12
SERPINE2 (protease nexin I) promotes extracellular matrix production and local invasion of pancreatic tumors in vivo. Cancer Res (2003) 1.12
Role of early multisystem organ failure as major risk factor for pancreatic infections and death in severe acute pancreatitis. Clin Gastroenterol Hepatol (2006) 1.12
Racial differences in exposure and glucuronidation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Cancer (2005) 1.10
The sequence dependence of human nucleotide excision repair efficiencies of benzo[a]pyrene-derived DNA lesions: insights into the structural factors that favor dual incisions. J Mol Biol (2009) 1.10
Pancreatic fungal infection. Pancreas (2003) 1.10
Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands inhibit growth of UACC903 and MCF7 human cancer cell lines. Toxicology (2007) 1.09
Early assessment of pancreatic infections and overall prognosis in severe acute pancreatitis by procalcitonin (PCT): a prospective international multicenter study. Ann Surg (2007) 1.09
Effects of immunosuppressive and immunostimulative treatment on pancreatic injury and mortality in severe acute experimental pancreatitis. Pancreas (2006) 1.08
Luteal-phase accentuation of acoustic startle response in women with premenstrual dysphoric disorder. Neuropsychopharmacology (2007) 1.08
Role of variation in the serotonin transporter protein gene (SLC6A4) in trait disturbances in the ventral anterior cingulate in bipolar disorder. Neuropsychopharmacology (2008) 1.08
Sequence context- and temperature-dependent nucleotide excision repair of a benzo[a]pyrene diol epoxide-guanine DNA adduct catalyzed by thermophilic UvrABC proteins. Biochemistry (2007) 1.08
Resistance of bulky DNA lesions to nucleotide excision repair can result from extensive aromatic lesion-base stacking interactions. Nucleic Acids Res (2011) 1.07
Persistent β2*-nicotinic acetylcholinergic receptor dysfunction in major depressive disorder. Am J Psychiatry (2012) 1.07
Development of a selective modulator of aryl hydrocarbon (Ah) receptor activity that exhibits anti-inflammatory properties. Chem Res Toxicol (2010) 1.06
Cough induced rib fracture, rupture of the diaphragm and abdominal herniation. World J Emerg Surg (2006) 1.06
Functional significance of UDP-glucuronosyltransferase variants in the metabolism of active tamoxifen metabolites. Cancer Res (2009) 1.06
Elimination of antiestrogenic effects of active tamoxifen metabolites by glucuronidation. Drug Metab Dispos (2007) 1.06
Omeprazole inhibits proliferation and modulates autophagy in pancreatic cancer cells. PLoS One (2011) 1.06
Biopsy of tumors of the musculoskeletal system. Dtsch Arztebl Int (2008) 1.06
Effects of the brain-derived neurotrophic growth factor val66met variation on hippocampus morphology in bipolar disorder. Neuropsychopharmacology (2008) 1.05
Intravenous ethanol infusion decreases human cortical γ-aminobutyric acid and N-acetylaspartate as measured with proton magnetic resonance spectroscopy at 4 tesla. Biol Psychiatry (2011) 1.04
CC-chemokine activation in acute pancreatitis: enhanced release of monocyte chemoattractant protein-1 in patients with local and systemic complications. Intensive Care Med (2003) 1.04
Ligand activation of peroxisome proliferator-activated receptor-beta/delta inhibits cell proliferation in human HaCaT keratinocytes. Mol Pharmacol (2008) 1.04
Suberoylanilide hydroxamic acid (SAHA), a histone deacetylase inhibitor, suppresses the growth of carcinogen-induced mammary tumors. Anticancer Res (2002) 1.04
Endotoxemia and endotoxin tolerance in patients with ARDS. Langenbecks Arch Surg (2008) 1.04
Dose-related behavioral, subjective, endocrine, and psychophysiological effects of the κ opioid agonist Salvinorin A in humans. Biol Psychiatry (2012) 1.04
Therapeutic efficacy of FTY720 in a rat model of NK-cell leukemia. Blood (2011) 1.03
Pancreatic injury in severe trauma: early diagnosis and therapy improve the outcome. Dig Surg (2002) 1.03
Mutagenesis and carcinogenesis induced by dibenzo[a,l]pyrene in the mouse oral cavity: a potential new model for oral cancer. Int J Cancer (2011) 1.03
PI-3K and Akt are mediators of AP-1 induction by 5-MCDE in mouse epidermal Cl41 cells. J Cell Biol (2004) 1.03
Antiglutamatergic strategies for ethanol detoxification: comparison with placebo and diazepam. Alcohol Clin Exp Res (2007) 1.03
Effects of haloperidol on the behavioral, subjective, cognitive, motor, and neuroendocrine effects of Delta-9-tetrahydrocannabinol in humans. Psychopharmacology (Berl) (2008) 1.03
Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-beta/delta antagonist GSK3787. Mol Pharmacol (2010) 1.02
Multiple gastrointestinal stromal tumors and bilateral pheochromocytoma in neurofibromatosis. World J Gastroenterol (2007) 1.02
Ploidy differences between hormone- and chemical carcinogen-induced rat mammary neoplasms: comparison to invasive human ductal breast cancer. Mol Carcinog (2002) 1.02
Dose-related modulation of event-related potentials to novel and target stimuli by intravenous Δ⁹-THC in humans. Neuropsychopharmacology (2012) 1.01
Importance of sphingosine kinase (SphK) as a target in developing cancer therapeutics and recent developments in the synthesis of novel SphK inhibitors. J Med Chem (2014) 1.01
Cyclooxygenase-2 is overexpressed in chronic pancreatitis. Pancreas (2002) 1.01
Long-term experience on surgical treatment of alveolar echinococcosis. Langenbecks Arch Surg (2008) 1.01