Published in Bioorg Med Chem Lett on June 17, 2002
A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish. Cell (2007) 6.31
A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo. Chem Biol (2006) 1.54
Ph2SO/Tf2O: a powerful promotor system in chemoselective glycosylations using thioglycosides. Org Lett (2003) 1.42
Antigen storage compartments in mature dendritic cells facilitate prolonged cytotoxic T lymphocyte cross-priming capacity. Proc Natl Acad Sci U S A (2009) 1.24
Distinct uptake mechanisms but similar intracellular processing of two different toll-like receptor ligand-peptide conjugates in dendritic cells. J Biol Chem (2007) 1.23
Absence of IHH and retention of PTHrP signalling in enchondromas and central chondrosarcomas. J Pathol (2005) 1.16
Transglycosidase activity of chitotriosidase: improved enzymatic assay for the human macrophage chitinase. J Biol Chem (2003) 1.16
The conformation of neurotensin bound to its G protein-coupled receptor. Proc Natl Acad Sci U S A (2003) 1.14
Specific cell-permeable inhibitor of proteasome trypsin-like sites selectively sensitizes myeloma cells to bortezomib and carfilzomib. Chem Biol (2011) 1.13
An RNA virus hijacks an incognito function of a DNA repair enzyme. Proc Natl Acad Sci U S A (2012) 1.08
Mixing of peptides and electrophilic traps gives rise to potent, broad-spectrum proteasome inhibitors. Org Biomol Chem (2007) 1.07
Biomarkers in the diagnosis of lysosomal storage disorders: proteins, lipids, and inhibodies. J Inherit Metab Dis (2011) 1.07
Differential regulation of doxorubicin-induced mitochondrial dysfunction and apoptosis by Bcl-2 in mammary adenocarcinoma (MTLn3) cells. J Biol Chem (2002) 1.05
Aberrant heparan sulfate proteoglycan localization, despite normal exostosin, in central chondrosarcoma. Am J Pathol (2009) 1.00
Inhibitors of protein: geranylgeranyl transferases. Curr Med Chem (2006) 0.99
Quantification of globotriaosylsphingosine in plasma and urine of fabry patients by stable isotope ultraperformance liquid chromatography-tandem mass spectrometry. Clin Chem (2012) 0.98
cDNA expression profiling of chondrosarcomas: Ollier disease resembles solitary tumours and alteration in genes coding for components of energy metabolism occurs with increasing grade. J Pathol (2005) 0.98
TINS, target immobilized NMR screening: an efficient and sensitive method for ligand discovery. Chem Biol (2005) 0.95
TLR ligand-peptide conjugate vaccines: toward clinical application. Adv Immunol (2012) 0.95
Sequential one-pot glycosylations using 1-hydroxyl and 1-thiodonors. Org Lett (2003) 0.94
Acetylene functionalized BODIPY dyes and their application in the synthesis of activity based proteasome probes. Bioorg Med Chem Lett (2007) 0.94
Conjugation of nucleosides and oligonucleotides by [3+2] cycloaddition. J Org Chem (2007) 0.93
Incorporation of non-natural amino acids improves cell permeability and potency of specific inhibitors of proteasome trypsin-like sites. J Med Chem (2013) 0.92
Bioorthogonal chemistry: applications in activity-based protein profiling. Acc Chem Res (2011) 0.91
Therapeutic potential of a synthetic peptide inhibitor of nuclear factor of activated T cells as antirestenotic agent. Arterioscler Thromb Vasc Biol (2006) 0.90
Azido-BODIPY acid reveals quantitative Staudinger-Bertozzi ligation in two-step activity-based proteasome profiling. Chembiochem (2008) 0.90
The C-terminal region of Escherichia coli UvrC contributes to the flexibility of the UvrABC nucleotide excision repair system. Nucleic Acids Res (2002) 0.89
2-Azidoalkoxy-7-hydro-8-oxoadenine derivatives as TLR7 agonists inducing dendritic cell maturation. Bioorg Med Chem Lett (2009) 0.89
Photoaffinity labeling in activity-based protein profiling. Top Curr Chem (2012) 0.88
Effective melanoma immunotherapy in mice by the skin-depigmenting agent monobenzone and the adjuvants imiquimod and CpG. PLoS One (2010) 0.88
Functions of base flipping in E. coli nucleotide excision repair. DNA Repair (Amst) (2008) 0.88
N-azidoacetylmannosamine-mediated chemical tagging of gangliosides. J Lipid Res (2007) 0.87
Glutathione conjugates and their synthetic derivatives as inhibitors of glutathione-dependent enzymes involved in cancer and drug resistance. Drug Metab Rev (2002) 0.87
Alkylated sugar amino acids: a new entry toward highly functionalized dipeptide isosters. Org Lett (2004) 0.87
Synthesis of mono-ADP-ribosylated oligopeptides using ribosylated amino acid building blocks. J Am Chem Soc (2010) 0.86
The role of noncartilage-specific molecules in differentiation of cartilaginous tumors: lessons from chondroblastoma and chondromyxoid fibroma. Cancer (2007) 0.86
Potential chemoprotective effects of the coffee components kahweol and cafestol palmitates via modification of hepatic N-acetyltransferase and glutathione S-transferase activities. Environ Mol Mutagen (2004) 0.85
Distinct intracellular signaling in tumor necrosis factor-related apoptosis-inducing ligand- and CD95 ligand-mediated apoptosis. J Biol Chem (2002) 0.85
Synthesis of oligoribonucleic acid conjugates using a cyclooctyne phosphoramidite. Org Lett (2010) 0.85
Fragment based lead discovery of small molecule inhibitors for the EPHA4 receptor tyrosine kinase. Eur J Med Chem (2011) 0.84
Furanosyl oxocarbenium ion stability and stereoselectivity. Angew Chem Int Ed Engl (2014) 0.84
1,3-Dimethyllumazine derivatives from Limnatis nilotica. J Nat Prod (2005) 0.84
Synthesis of sugar nucleotides by application of phosphoramidites. J Org Chem (2008) 0.84
N-tetradecylcarbamyl lipopeptides as novel agonists for Toll-like receptor 2. J Med Chem (2014) 0.84
A combinatorial approach toward the generation of ambiphilic peptide-based inhibitors of protein:geranylgeranyl transferase-1. J Comb Chem (2005) 0.84
Chirality of TLR-2 ligand Pam3CysSK4 in fully synthetic peptide conjugates critically influences the induction of specific CD8+ T-cells. Mol Immunol (2008) 0.83
Enhanced global genome nucleotide excision repair reduces UV carcinogenesis and nullifies strand bias in p53 mutations in Csb-/- mice. J Invest Dermatol (2010) 0.83
A cleavable linker based on the levulinoyl ester for activity-based protein profiling. Angew Chem Int Ed Engl (2010) 0.83
Influence of O6 in mannosylations using benzylidene protected donors: stereoelectronic or conformational effects? J Org Chem (2013) 0.83
Apoptosis induced by extracellular ATP in the mouse neuroblastoma cell line N1E-115: studies on involvement of P2 receptors and adenosine. Biochem Pharmacol (2002) 0.83
NMR solution structure of poliovirus uridylyated peptide linked to the genome (VPgpU). Peptides (2010) 0.82
Modification of picornavirus genomic RNA using 'click' chemistry shows that unlinking of the VPg peptide is dispensable for translation and replication of the incoming viral RNA. Nucleic Acids Res (2013) 0.82
A two-armed lanthanoid-chelating paramagnetic NMR probe linked to proteins via thioether linkages. Chemistry (2014) 0.82
Structure of an anti-Lewis X Fab fragment in complex with its Lewis X antigen. Structure (2004) 0.82
Fluorous linker facilitated synthesis of teichoic acid fragments. Org Lett (2012) 0.81
Discovery of a potent and highly β1 specific proteasome inhibitor from a focused library of urea-containing peptide vinyl sulfones and peptide epoxyketones. Org Biomol Chem (2011) 0.81
Poly(ethylene glycol)-based stable isotope labeling reagents for the quantitative analysis of low molecular weight metabolites by LC-MS. Anal Chem (2008) 0.81
Direct and two-step bioorthogonal probes for Bruton's tyrosine kinase based on ibrutinib: a comparative study. Org Biomol Chem (2015) 0.80
Bioorthogonal deprotection on the dendritic cell surface for chemical control of antigen cross-presentation. Angew Chem Int Ed Engl (2015) 0.80
Stereoselective ribosylation of amino acids. Org Lett (2013) 0.80
Interleukin-2 activated NK cells do not use the CD95L- and TRAIL-pathways in the rapid induction of apoptosis of rat colon carcinoma CC531s cells. Immunobiology (2003) 0.80
Design, synthesis and evaluation of high-affinity binders for the celiac disease associated HLA-DQ2 molecule. Mol Immunol (2009) 0.80
Reduced liver uptake of arterially infused melphalan during retrograde rat liver perfusion with unaffected liver tumor uptake. J Pharmacol Exp Ther (2002) 0.80
A general synthetic method toward uridylylated picornavirus VPg proteins. J Pept Sci (2013) 0.79
Modulation of cytostatic efficacy of melphalan by glutathione: mechanisms and efficacy. Chem Biol Interact (2002) 0.79
Acylazetine as a dienophile in bioorthogonal inverse electron-demand Diels-Alder ligation. Org Lett (2014) 0.79
Synthesis of 2-alkoxy-8-hydroxyadenylpeptides: towards synthetic epitope-based vaccines. Bioorg Med Chem Lett (2006) 0.79
Peptidomimetic glutathione analogues as novel gammaGT stable GST inhibitors. Bioorg Med Chem (2002) 0.79
Exploring the conformational and biological versatility of β-turn-modified gramicidin S by using sugar amino acid homologues that vary in ring size. Chemistry (2011) 0.79
An adamantyl amino acid containing gramicidin S analogue with broad spectrum antibacterial activity and reduced hemolytic activity. Chemistry (2010) 0.79
Melphalan antitumor efficacy and hepatotoxicity: the effect of variable infusion duration in the hepatic artery. J Pharmacol Exp Ther (2003) 0.79
Immunohistochemical detection of melphalan-DNA adducts in colon cancer cells in vitro and human colorectal liver tumours in vivo. Biochem Pharmacol (2004) 0.78
Automated parallel solid-phase synthesis and anticancer screening of a library of peptide-tethered platinum(II) complexes. J Comb Chem (2003) 0.78
Synthesis of nucleotidylated poliovirus VPg proteins. J Org Chem (2010) 0.78
Probing the potential of platinum(II) complexes for the inhibition of thiol-dependent enzymatic activity. J Inorg Biochem (2005) 0.78
Synthesis and evaluation of strand and turn modified ring-extended gramicidin S derivatives. Bioorg Med Chem (2011) 0.78
Azathioprine-induced microsatellite instability is not observed in skin carcinomas of organ transplant recipients. J Invest Dermatol (2009) 0.78
Design of azidoproline containing gluten peptides to suppress CD4+ T-cell responses associated with celiac disease. Bioorg Med Chem (2007) 0.78
Inhibition of the multidrug resistance protein 1 (MRP1) by peptidomimetic glutathione-conjugate analogs. Mol Pharmacol (2002) 0.78
A mutasynthesis approach with a Penicillium chrysogenum ΔroqA strain yields new roquefortine D analogues. Chembiochem (2015) 0.78
A versatile one-pot procedure to phosphate monoesters and pyrophosphates using di(p-methoxybenzyl)-N,N-diisopropylphosphoramidite. Org Lett (2008) 0.78
Monofunctionally trans-diammine platinum(II)-modified peptide nucleic acid oligomers: a new generation of potential antisense drugs. Chemistry (2002) 0.78
Physicochemical property consensus sequences for functional analysis, design of multivalent antigens and targeted antivirals. BMC Bioinformatics (2012) 0.77
Selective modulation of nuclear factor of activated T-cell function in restenosis by a potent bipartite peptide inhibitor. Circ Res (2011) 0.77
Synthetic developments towards PNA-peptide conjugates. Curr Opin Chem Biol (2003) 0.77
A targeted peptide nucleic acid to down-regulate mouse microsomal triglyceride transfer protein expression in hepatocytes. Bioconjug Chem (2003) 0.77
Automated solid phase synthesis of teichoic acids. Chem Commun (Camb) (2011) 0.77
Facile synthesis and application of uniformly 13C, 15N-labeled phosphotyrosine for ligand binding studies. Bioorg Med Chem Lett (2006) 0.77
Fully automated sequential solid phase approach towards viral RNA-nucleopeptides. Chem Commun (Camb) (2012) 0.77
Solid-phase synthesis of succinylhydroxamate peptides: functionalized matrix metalloproteinase inhibitors. Org Lett (2006) 0.77
A practical synthesis of capped 4-methylumbelliferyl hyaluronan disaccharides and tetrasaccharides as potential hyaluronidase substrates. Carbohydr Res (2011) 0.77
The interaction of peptide-tethered platinum(II) complexes with DNA. J Inorg Biochem (2003) 0.77
A versatile approach towards regioselective platinated DNA sequences. Chemistry (2003) 0.77
Synthesis and evaluation of D-gluco-pyranocyclopropyl amines as potential glucosidase inhibitors. Bioorg Med Chem Lett (2009) 0.76
Rat colon carcinoma cells that survived systemic immune surveillance are less sensitive to NK-cell mediated apoptosis. Clin Exp Metastasis (2003) 0.76