PubRank

Krishna Saxena

Author PubWeight™ 27.45‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis. Proc Natl Acad Sci U S A 2006 1.96
2 NMR characterization of kinase p38 dynamics in free and ligand-bound forms. Angew Chem Int Ed Engl 2006 1.61
3 Novel techniques for weak alignment of proteins in solution using chemical tags coordinating lanthanide ions. J Biomol NMR 2004 1.22
4 Peptide binding induces large scale changes in inter-domain mobility in human Pin1. J Biol Chem 2003 1.18
5 NMR backbone assignment of a protein kinase catalytic domain by a combination of several approaches: application to the catalytic subunit of cAMP-dependent protein kinase. Chembiochem 2004 1.10
6 Discovery of a new class of inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B by biology-oriented synthesis. Angew Chem Int Ed Engl 2008 1.09
7 Brunsvicamides A-C: sponge-related cyanobacterial peptides with Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory activity. J Med Chem 2006 1.09
8 Polo-like kinase 1-mediated phosphorylation stabilizes Pin1 by inhibiting its ubiquitination in human cells. J Biol Chem 2005 1.03
9 NMR analysis of a Tau phosphorylation pattern. J Am Chem Soc 2006 1.00
10 Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase A (MptpA) inhibitors based on natural products and a fragment-based approach. Chembiochem 2005 0.96
11 NMR backbone assignment of the mitogen-activated protein (MAP) kinase p38. J Biomol NMR 2005 0.93
12 Identification of inhibitors for mycobacterial protein tyrosine phosphatase B (MptpB) by biology-oriented synthesis (BIOS). Chem Asian J 2007 0.92
13 Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling. Cancer Cell 2013 0.91
14 Spectroscopic, molecular modeling, and NMR-spectroscopic investigation of the binding mode of the natural alkaloids berberine and sanguinarine to human telomeric G-quadruplex DNA. ACS Chem Biol 2012 0.85
15 NMR solution structure and dynamics of the peptidyl-prolyl cis-trans isomerase domain of the trigger factor from Mycoplasma genitalium compared to FK506-binding protein. J Mol Biol 2002 0.84
16 Biomolecular NMR: a chaperone to drug discovery. Curr Opin Chem Biol 2006 0.84
17 Study of E. coli Hfq's RNA annealing acceleration and duplex destabilization activities using substrates with different GC-contents. Nucleic Acids Res 2012 0.83
18 The apo-structure of the low molecular weight protein-tyrosine phosphatase A (MptpA) from Mycobacterium tuberculosis allows for better target-specific drug development. J Biol Chem 2012 0.80
19 NMR backbone assignment of the N-terminal domain of human HSP90. J Biomol NMR 2006 0.79
20 Folding and activity of cAMP-dependent protein kinase mutants. FEBS Lett 2005 0.79
21 Molecular Mechanism of SSR128129E, an Extracellularly Acting, Small-Molecule, Allosteric Inhibitor of FGF Receptor Signaling. Cancer Cell 2016 0.78
22 Recombinant expression and purification of human TATA binding protein using a chimeric fusion. Protein Expr Purif 2012 0.78
23 Isotope labeling in mammalian cells. Methods Mol Biol 2012 0.77
24 Backbone NMR assignment of the low-molecular-weight protein tyrosine phosphatase (MPtpA) from Mycobacterium tuberculosis. J Biomol NMR 2005 0.77
25 QSAR-by-NMR: quantitative insights into structural determinants for binding affinity by analysis of 1H/15N chemical shift differences in MMP-3 ligands. Bioorg Med Chem Lett 2005 0.76
26 MOTOR: model assisted software for NMR structure determination. Proteins 2013 0.76
27 1H, 13C and 15N backbone resonance assignment of the peptidyl-prolyl cis-trans isomerase Pin1. J Biomol NMR 2002 0.76
28 How much NMR data is required to determine a protein-ligand complex structure? Chembiochem 2005 0.76
29 Atomic-level structure characterization of an ultrafast folding mini-protein denatured state. PLoS One 2012 0.76
30 Backbone NMR assignment of the human E2 ubiquitin conjugating enzyme UbcH5alpha (F72K,F82S) double mutant. J Biomol NMR 2005 0.75
31 Backbone NMR assignment of the C-terminal haemopexin-like domain (HPLD) of human matrix metalloproteinase MMP-13. J Biomol NMR 2005 0.75
32 1H, 13C and 15N backbone resonance assignment of the Hsp90 binding domain of human Cdc37. J Biomol NMR 2005 0.75
33 ¹H, ¹³C and ¹⁵N assignment of D2 domain of human fibroblast growth factor receptor 4. Biomol NMR Assign 2012 0.75
34 Protocol for aerosol-free recombinant production and NMR analysis of prion proteins. J Biomol NMR 2014 0.75