| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Depressive-like effects of the kappa-opioid receptor agonist salvinorin A on behavior and neurochemistry in rats.
|
J Pharmacol Exp Ther
|
2005
|
2.66
|
|
2
|
Structural brain magnetic resonance imaging of limbic and thalamic volumes in pediatric bipolar disorder.
|
Am J Psychiatry
|
2005
|
2.18
|
|
3
|
Default mode network abnormalities in bipolar disorder and schizophrenia.
|
Psychiatry Res
|
2010
|
1.84
|
|
4
|
Abnormal medial prefrontal cortex resting-state connectivity in bipolar disorder and schizophrenia.
|
Neuropsychopharmacology
|
2011
|
1.68
|
|
5
|
Myelin and axon abnormalities in schizophrenia measured with magnetic resonance imaging techniques.
|
Biol Psychiatry
|
2013
|
1.64
|
|
6
|
Synthesis and in vitro pharmacological evaluation of salvinorin A analogues modified at C(2).
|
Bioorg Med Chem Lett
|
2005
|
1.60
|
|
7
|
Abnormal glutamatergic neurotransmission and neuronal-glial interactions in acute mania.
|
Biol Psychiatry
|
2008
|
1.58
|
|
8
|
CD-1 and Balb/cJ mice do not show enduring antidepressant-like effects of ketamine in tests of acute antidepressant efficacy.
|
Psychopharmacology (Berl)
|
2011
|
1.57
|
|
9
|
Synthesis and in vitro evaluation of salvinorin A analogues: effect of configuration at C(2) and substitution at C(18).
|
Bioorg Med Chem Lett
|
2006
|
1.55
|
|
10
|
Kappa-opioid ligands in the study and treatment of mood disorders.
|
Pharmacol Ther
|
2009
|
1.42
|
|
11
|
Elevated gamma-aminobutyric acid levels in chronic schizophrenia.
|
Biol Psychiatry
|
2010
|
1.38
|
|
12
|
Rapid enhancement of glutamatergic neurotransmission in bipolar depression following treatment with riluzole.
|
Neuropsychopharmacology
|
2009
|
1.36
|
|
13
|
The kappa-opioid agonist U69,593 blocks cocaine-induced enhancement of brain stimulation reward.
|
Biol Psychiatry
|
2008
|
1.31
|
|
14
|
A polymorphism in the norepinephrine transporter gene alters promoter activity and is associated with attention-deficit hyperactivity disorder.
|
Proc Natl Acad Sci U S A
|
2006
|
1.23
|
|
15
|
Behavioral and anatomical interactions between dopamine and corticotropin-releasing factor in the rat.
|
J Neurosci
|
2006
|
1.22
|
|
16
|
Antidepressant-like effects of uridine and omega-3 fatty acids are potentiated by combined treatment in rats.
|
Biol Psychiatry
|
2005
|
1.20
|
|
17
|
Duration of action of a broad range of selective κ-opioid receptor antagonists is positively correlated with c-Jun N-terminal kinase-1 activation.
|
Mol Pharmacol
|
2011
|
1.20
|
|
18
|
Abnormalities in mitochondrial structure in cells from patients with bipolar disorder.
|
Am J Pathol
|
2010
|
1.19
|
|
19
|
Standard protecting groups create potent and selective kappa opioids: salvinorin B alkoxymethyl ethers.
|
Bioorg Med Chem
|
2007
|
1.15
|
|
20
|
8-epi-Salvinorin B: crystal structure and affinity at the kappa opioid receptor.
|
Beilstein J Org Chem
|
2007
|
1.14
|
|
21
|
T2 relaxation time abnormalities in bipolar disorder and schizophrenia.
|
Magn Reson Med
|
2010
|
1.13
|
|
22
|
Creatine abnormalities in schizophrenia and bipolar disorder.
|
Psychiatry Res
|
2009
|
1.11
|
|
23
|
Mutations in the dopamine beta-hydroxylase gene are associated with human norepinephrine deficiency.
|
Am J Med Genet
|
2002
|
1.11
|
|
24
|
Low-field magnetic stimulation in bipolar depression using an MRI-based stimulator.
|
Am J Psychiatry
|
2004
|
1.10
|
|
25
|
Repeated exposure to the κ-opioid receptor agonist salvinorin A modulates extracellular signal-regulated kinase and reward sensitivity.
|
Biol Psychiatry
|
2011
|
1.10
|
|
26
|
Cortical gray matter differences identified by structural magnetic resonance imaging in pediatric bipolar disorder.
|
Bipolar Disord
|
2005
|
1.07
|
|
27
|
Exposure to the selective kappa-opioid receptor agonist salvinorin A modulates the behavioral and molecular effects of cocaine in rats.
|
Neuropsychopharmacology
|
2008
|
1.07
|
|
28
|
Multinuclear magnetic resonance spectroscopy of high-energy phosphate metabolites in human brain following oral supplementation of creatine-monohydrate.
|
Psychiatry Res
|
2003
|
1.04
|
|
29
|
Dose-related behavioral, subjective, endocrine, and psychophysiological effects of the κ opioid agonist Salvinorin A in humans.
|
Biol Psychiatry
|
2012
|
1.04
|
|
30
|
Differential signaling properties at the kappa opioid receptor of 12-epi-salvinorin A and its analogues.
|
Bioorg Med Chem Lett
|
2011
|
1.03
|
|
31
|
Salvinorin A and derivatives: protection from metabolism does not prolong short-term, whole-brain residence.
|
Neuropharmacology
|
2009
|
1.00
|
|
32
|
Role of kappa-opioid receptors in the effects of salvinorin A and ketamine on attention in rats.
|
Psychopharmacology (Berl)
|
2010
|
1.00
|
|
33
|
Blockade of astrocytic glutamate uptake in rats induces signs of anhedonia and impaired spatial memory.
|
Neuropsychopharmacology
|
2010
|
1.00
|
|
34
|
Modification of the furan ring of salvinorin A: identification of a selective partial agonist at the kappa opioid receptor.
|
Bioorg Med Chem
|
2008
|
0.99
|
|
35
|
N-methylacetamide analog of salvinorin A: a highly potent and selective kappa-opioid receptor agonist with oral efficacy.
|
J Pharmacol Exp Ther
|
2007
|
0.98
|
|
36
|
Omega-3 fatty acid treatment and T(2) whole brain relaxation times in bipolar disorder.
|
Am J Psychiatry
|
2004
|
0.98
|
|
37
|
Activation of raphe efferents to the medial prefrontal cortex by corticotropin-releasing factor: correlation with anxiety-like behavior.
|
Biol Psychiatry
|
2007
|
0.97
|
|
38
|
Blockade of astrocytic glutamate uptake in the prefrontal cortex induces anhedonia.
|
Neuropsychopharmacology
|
2012
|
0.97
|
|
39
|
Ablation of kappa-opioid receptors from brain dopamine neurons has anxiolytic-like effects and enhances cocaine-induced plasticity.
|
Neuropsychopharmacology
|
2013
|
0.97
|
|
40
|
Role of the bed nucleus of the stria terminalis (BST) in the expression of conditioned fear.
|
Ann N Y Acad Sci
|
2006
|
0.96
|
|
41
|
Long-acting κ opioid antagonists nor-BNI, GNTI and JDTic: pharmacokinetics in mice and lipophilicity.
|
BMC Pharmacol
|
2012
|
0.95
|
|
42
|
31Phosphorus magnetic resonance spectroscopy study of tissue specific changes in high energy phosphates before and after sertraline treatment of geriatric depression.
|
Int J Geriatr Psychiatry
|
2009
|
0.95
|
|
43
|
Clinical characteristics influencing age at onset in psychotic disorders.
|
Compr Psychiatry
|
2008
|
0.95
|
|
44
|
Corticotropin-releasing factor (CRF)-induced disruption of attention in rats is blocked by the κ-opioid receptor antagonist JDTic.
|
Neuropsychopharmacology
|
2012
|
0.93
|
|
45
|
Functional connectivity of left Heschl's gyrus in vulnerability to auditory hallucinations in schizophrenia.
|
Schizophr Res
|
2012
|
0.93
|
|
46
|
Relationship between genetic variation in the glutaminase gene GLS1 and brain glutamine/glutamate ratio measured in vivo.
|
Biol Psychiatry
|
2011
|
0.91
|
|
47
|
A genome-wide RNAi screen in Caenorhabditis elegans identifies the nicotinic acetylcholine receptor subunit ACR-7 as an antipsychotic drug target.
|
PLoS Genet
|
2013
|
0.91
|
|
48
|
Water and metabolite transverse T2 relaxation time abnormalities in the white matter in schizophrenia.
|
Schizophr Res
|
2012
|
0.91
|
|
49
|
Brain metabolite concentrations across cortical regions in healthy adults.
|
Brain Res
|
2010
|
0.91
|
|
50
|
Age-related changes in brain energetics and phospholipid metabolism.
|
NMR Biomed
|
2010
|
0.90
|
|
51
|
Clozapine interaction with phosphatidyl inositol 3-kinase (PI3K)/insulin-signaling pathway in Caenorhabditis elegans.
|
Neuropsychopharmacology
|
2009
|
0.90
|
|
52
|
Behavioral effects of short-term administration of lithium and valproic acid in rats.
|
Brain Res
|
2006
|
0.90
|
|
53
|
Relationship of neurocognitive deficits to diagnosis and symptoms across affective and non-affective psychoses.
|
Schizophr Res
|
2011
|
0.90
|
|
54
|
Creatine kinase and ATP synthase reaction rates in human frontal lobe measured by ³¹P magnetization transfer spectroscopy at 4T.
|
Magn Reson Imaging
|
2012
|
0.89
|
|
55
|
Bioavailability and lack of toxicity of S-adenosyl-L-methionine (SAMe) in humans.
|
Pharmacotherapy
|
2004
|
0.89
|
|
56
|
Decreased glutamate/glutamine levels may mediate cytidine's efficacy in treating bipolar depression: a longitudinal proton magnetic resonance spectroscopy study.
|
Neuropsychopharmacology
|
2009
|
0.87
|
|
57
|
Cerebellar blood volume in bipolar patients correlates with medication.
|
Biol Psychiatry
|
2002
|
0.87
|
|
58
|
Oral choline increases choline metabolites in human brain.
|
Psychiatry Res
|
2004
|
0.86
|
|
59
|
Electroconvulsive seizures stimulate glial proliferation and reduce expression of Sprouty2 within the prefrontal cortex of rats.
|
Biol Psychiatry
|
2007
|
0.86
|
|
60
|
Brain-to-serum lithium ratio and age: an in vivo magnetic resonance spectroscopy study.
|
Am J Psychiatry
|
2002
|
0.86
|
|
61
|
Antidepressant-like effects of cranial stimulation within a low-energy magnetic field in rats.
|
Biol Psychiatry
|
2005
|
0.85
|
|
62
|
Tactile, olfactory, and gustatory hallucinations in psychotic disorders: a descriptive study.
|
Ann Acad Med Singapore
|
2009
|
0.85
|
|
63
|
Antidepressant-like effects of cytidine in the forced swim test in rats.
|
Biol Psychiatry
|
2002
|
0.84
|
|
64
|
Auditory hallucinations in a cross-diagnostic sample of psychotic disorder patients: a descriptive, cross-sectional study.
|
Compr Psychiatry
|
2011
|
0.84
|
|
65
|
Coenzyme Q10 effects on creatine kinase activity and mood in geriatric bipolar depression.
|
J Geriatr Psychiatry Neurol
|
2012
|
0.83
|
|
66
|
Triacetyluridine (TAU) decreases depressive symptoms and increases brain pH in bipolar patients.
|
Exp Clin Psychopharmacol
|
2008
|
0.83
|
|
67
|
Expression of noradrenergic alpha1, serotoninergic 5HT2a and dopaminergic D2 receptors on neurons activated by typical and atypical antipsychotic drugs.
|
Prog Neuropsychopharmacol Biol Psychiatry
|
2006
|
0.83
|
|
68
|
Behavioral effects of clozapine: involvement of trace amine pathways in C. elegans and M. musculus.
|
Brain Res
|
2011
|
0.82
|
|
69
|
In vivo proton magnetic resonance spectroscopy of the temporal lobe in Alzheimer's disease.
|
Prog Neuropsychopharmacol Biol Psychiatry
|
2004
|
0.82
|
|
70
|
S-adenosyl-L-methionine: effects on brain bioenergetic status and transverse relaxation time in healthy subjects.
|
Biol Psychiatry
|
2003
|
0.82
|
|
71
|
How blind is double-blind? A study of fish oil versus placebo.
|
Prostaglandins Leukot Essent Fatty Acids
|
2002
|
0.82
|
|
72
|
Brain gamma-aminobutyric acid (GABA) abnormalities in bipolar disorder.
|
Bipolar Disord
|
2013
|
0.81
|
|
73
|
Transient receptor potential melastatin (TRPM) channels mediate clozapine-induced phenotypes in Caenorhabditis elegans.
|
J Neurogenet
|
2014
|
0.81
|
|
74
|
Variations in the dopamine beta-hydroxylase gene are not associated with the autonomic disorders, pure autonomic failure, or multiple system atrophy.
|
Am J Med Genet A
|
2003
|
0.81
|
|
75
|
Exploring the role of central astrocytic glutamate uptake in ethanol reward in mice.
|
Alcohol Clin Exp Res
|
2014
|
0.80
|
|
76
|
Omega-3 fatty acid treatment, with or without cytidine, fails to show therapeutic properties in bipolar disorder: a double-blind, randomized add-on clinical trial.
|
J Clin Psychopharmacol
|
2012
|
0.80
|
|
77
|
Lack of effect of sublingual salvinorin A, a naturally occurring kappa opioid, in humans: a placebo-controlled trial.
|
Psychopharmacology (Berl)
|
2010
|
0.80
|
|
78
|
Selective κ opioid antagonists nor-BNI, GNTI and JDTic have low affinities for non-opioid receptors and transporters.
|
PLoS One
|
2013
|
0.80
|
|
79
|
Detection of intranasally delivered bone marrow-derived mesenchymal stromal cells in the lesioned mouse brain: a cautionary report.
|
Stem Cells Int
|
2011
|
0.80
|
|
80
|
Differential hippocampal gene expression and pathway analysis in an etiology-based mouse model of major depressive disorder.
|
Am J Med Genet B Neuropsychiatr Genet
|
2014
|
0.79
|
|
81
|
Categorical vs dimensional classifications of psychotic disorders.
|
Compr Psychiatry
|
2012
|
0.79
|
|
82
|
Lovastatin potentiates the antidepressant efficacy of fluoxetine in rats.
|
Pharmacol Biochem Behav
|
2008
|
0.79
|
|
83
|
Cerebral blood volume and clinical changes on the third day of placebo substitution for SSRI treatment.
|
Biol Psychiatry
|
2003
|
0.78
|
|
84
|
A placebo-controlled trial of acetyl-L-carnitine and α-lipoic acid in the treatment of bipolar depression.
|
J Clin Psychopharmacol
|
2013
|
0.78
|
|
85
|
Can't get enough of that dopamine.
|
Am J Psychiatry
|
2007
|
0.78
|
|
86
|
Selective serotonin reuptake inhibitor discontinuation syndrome is associated with a rostral anterior cingulate choline metabolite decrease: a proton magnetic resonance spectroscopic imaging study.
|
Biol Psychiatry
|
2003
|
0.77
|
|
87
|
Neuropsychological functioning predicts community outcomes in affective and non-affective psychoses: a 6-month follow-up.
|
Schizophr Res
|
2013
|
0.77
|
|
88
|
Corticotropin-releasing factor from the rat brain measured by protein immunoblot.
|
Peptides
|
2005
|
0.77
|
|
89
|
Salvinorin B meth-oxy-methyl ether.
|
Acta Crystallogr Sect E Struct Rep Online
|
2012
|
0.77
|
|
90
|
Glial abnormalities in mood disorders.
|
Harv Rev Psychiatry
|
2014
|
0.77
|
|
91
|
Improving the pedagogy associated with the teaching of psychopharmacology.
|
Acad Psychiatry
|
2007
|
0.76
|
|
92
|
Naltrexone in bipolar disorder with depression: a double-blind, placebo-controlled study.
|
J Clin Psychopharmacol
|
2014
|
0.76
|
|
93
|
Anxiety disorder comorbidity in bipolar disorder, schizophrenia and schizoaffective disorder.
|
Psychopathology
|
2012
|
0.76
|
|
94
|
Alterations of brain anatomy in mouse model of MDD created by replacement of homologous mouse DNA sequence with an illness-associated 6-base human CREB1 promoter sequence.
|
Am J Med Genet B Neuropsychiatr Genet
|
2013
|
0.76
|
|
95
|
Social functioning and age across affective and nonaffective psychoses.
|
J Nerv Ment Dis
|
2015
|
0.76
|
|
96
|
Mesial temporal lobe Cho to Cr(PCr) ratio asymmetry in chronic schizophrenics.
|
Schizophr Res
|
2002
|
0.76
|
|
97
|
Effects of the anticonvulsant lacosamide compared to valproate and lamotrigine on cocaine-enhanced reward in rats.
|
Brain Res
|
2012
|
0.76
|
|
98
|
Antidepressant effects of open label treatment with coenzyme Q10 in geriatric bipolar depression.
|
J Clin Psychopharmacol
|
2015
|
0.75
|
|
99
|
Genomewide association analyses of electrophysiological endophenotypes for schizophrenia and psychotic bipolar disorders: a preliminary report.
|
Am J Med Genet B Neuropsychiatr Genet
|
2015
|
0.75
|
|
100
|
Oral SAMe in persistent treatment-refractory bipolar depression: a double-blind, randomized clinical trial.
|
J Clin Psychopharmacol
|
2014
|
0.75
|
|
101
|
From asylum to hospital to psychiatric health care system.
|
Am J Psychiatry
|
2007
|
0.75
|