Published in J Endocrinol on June 01, 2002
Overexpression of SIRT1 protects pancreatic beta-cells against cytokine toxicity by suppressing the nuclear factor-kappaB signaling pathway. Diabetes (2008) 2.00
Conditional and specific NF-kappaB blockade protects pancreatic beta cells from diabetogenic agents. Proc Natl Acad Sci U S A (2006) 1.85
Tissue-specific effects of the nuclear factor kappaB subunit p50 on myocardial ischemia-reperfusion injury. Am J Pathol (2007) 1.04
Cytokines in the Progression of Pancreatic β-Cell Dysfunction. Int J Endocrinol (2010) 0.99
Roles of Bcl-3 in the pathogenesis of murine type 1 diabetes. Diabetes (2010) 0.95
Sulfuretin protects against cytokine-induced beta-cell damage and prevents streptozotocin-induced diabetes. Exp Mol Med (2010) 0.92
Nardostachys jatamansi extract protects against cytokine-induced beta-cell damage and streptozotocin-induced diabetes. World J Gastroenterol (2010) 0.87
Heat shock protein 27 overexpression mitigates cytokine-induced islet apoptosis and streptozotocin-induced diabetes. Endocrinology (2009) 0.85
Dietary zinc reduction, pyruvate supplementation, or zinc transporter 5 knockout attenuates β-cell death in nonobese diabetic mice, islets, and insulinoma cells. J Nutr (2012) 0.78
Proteomic analysis of brain protein expression levels in NF-kappabeta p50 -/- homozygous knockout mice. Brain Res (2008) 0.77
Sustained NF-κB activation and inhibition in β-cells have minimal effects on function and islet transplant outcomes. PLoS One (2013) 0.76
Is a new immune response mediator in the NF-kappaB pathway--SUMO-4--related to type 1 diabetes? Rev Diabet Stud (2005) 0.75
Polyphenols isolated from Broussonetia kazinoki prevent cytokine-induced β-cell damage and the development of type 1 diabetes. Exp Mol Med (2015) 0.75
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature (1999) 12.95
Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nat Med (2000) 8.89
Nitric oxide dioxygenase: an enzymic function for flavohemoglobin. Proc Natl Acad Sci U S A (1998) 3.47
Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation. Nat Med (2001) 2.91
Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse. J Neurosci (1997) 2.91
Status epilepticus: an independent outcome predictor after cerebral anoxia. Neurology (2007) 2.67
Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice. J Immunol (1996) 2.55
Adenosine inhibits IL-12 and TNF-[alpha] production via adenosine A2a receptor-dependent and independent mechanisms. FASEB J (2000) 2.53
Selective pharmacological inhibition of distinct nitric oxide synthase isoforms. Biochem Pharmacol (1996) 2.48
DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite. Proc Natl Acad Sci U S A (1996) 2.38
Clinical spectrum of urinary tract infections due on nontyphoidal Salmonella species. Clin Infect Dis (1996) 2.33
Corynebacterium group D2 as a cause of alkaline-encrusted cystitis: report of four cases and characterization of the organisms. J Clin Microbiol (1985) 2.01
Role of resident peritoneal macrophages and mast cells in chemokine production and neutrophil migration in acute inflammation: evidence for an inhibitory loop involving endogenous IL-10. J Immunol (1999) 1.99
Vascular hyporeactivity to vasoconstrictor agents and hemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide. Proc Natl Acad Sci U S A (1993) 1.96
Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase. Proc Natl Acad Sci U S A (1994) 1.83
Genetic disruption of poly (ADP-ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia/reperfusion injury. Circ Res (1998) 1.80
Activation of poly(ADP-ribose) polymerase contributes to development of doxorubicin-induced heart failure. J Pharmacol Exp Ther (2002) 1.69
Location of the serine residue involved in the linkage between the terminal protein and the DNA of phage phi 29. Nucleic Acids Res (1985) 1.68
Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity. Br J Pharmacol (1995) 1.67
Endocannabinoids and cannabinoid receptors in ischaemia-reperfusion injury and preconditioning. Br J Pharmacol (2007) 1.65
Poly (ADP-ribose) synthetase mediates intestinal mucosal barrier dysfunction after mesenteric ischemia. Shock (2000) 1.64
Circulating methemoglobin and nitrite/nitrate concentrations as indicators of nitric oxide overproduction in critically ill children with septic shock. Crit Care Med (1997) 1.61
Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite. J Clin Invest (1997) 1.60
Inosine improves gut permeability and vascular reactivity in endotoxic shock. Crit Care Med (2001) 1.57
In vitro and in vivo study of stone formation by Corynebacterium group D2 (Corynebacterium urealyticum). J Clin Microbiol (1986) 1.54
Antimicrobial susceptibility of Corynebacterium group D2. Antimicrob Agents Chemother (1985) 1.54
Poly(ADP-ribose) synthetase activation mediates increased permeability induced by peroxynitrite in Caco-2BBe cells. Gastroenterology (1998) 1.54
Localizing antithrombotic and vasodilatory activity with a novel, ultrafast nitric oxide donor. J Med Chem (1996) 1.54
Nitric oxide sensitivity of the aconitases. J Biol Chem (1997) 1.51
Primary structure and inhibition of protein synthesis in eukaryotic cell-free system of a novel thionin, gamma-hordothionin, from barley endosperm. Eur J Biochem (1990) 1.49
Effects of a novel guanylyl cyclase inhibitor on the vascular actions of nitric oxide and peroxynitrite in immunostimulated smooth muscle cells and in endotoxic shock. Crit Care Med (1999) 1.49
Peroxynitrite-mediated DNA strand breakage activates poly-adenosine diphosphate ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide. J Immunol (1996) 1.48
Intermittent high glucose enhances ICAM-1, VCAM-1, E-selectin and interleukin-6 expression in human umbilical endothelial cells in culture: the role of poly(ADP-ribose) polymerase. J Thromb Haemost (2004) 1.48
Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects. J Exp Med (1997) 1.47
Inosine inhibits inflammatory cytokine production by a posttranscriptional mechanism and protects against endotoxin-induced shock. J Immunol (2000) 1.47
Effects of norepinephrine on the distribution of intestinal blood flow and tissue adenosine triphosphate content in endotoxic shock. Crit Care Med (2000) 1.47
Reactive oxygen species mediate a cellular 'memory' of high glucose stress signalling. Diabetologia (2007) 1.46
[Soft-tissue infection caused by Aeromonas hydrophila]. Enferm Infecc Microbiol Clin (1995) 1.46
Crucial role of endogenous interleukin-10 production in myocardial ischemia/reperfusion injury. Circulation (2000) 1.46
European Committee on Antimicrobial Susceptibility Testing (EUCAST) Technical Notes on antimicrobial susceptibility testing. Clin Microbiol Infect (2006) 1.45
Evaluation of API Coryne system for identifying coryneform bacteria. J Clin Pathol (1994) 1.44
Calcium entry blockers increase interleukin-10 production in endotoxemia. Shock (1997) 1.43
Role of tumour necrosis factor in the induction of nitric oxide synthase in a rat model of endotoxin shock. Br J Pharmacol (1993) 1.40
Suppression of macrophage inflammatory protein (MIP)-1alpha production and collagen-induced arthritis by adenosine receptor agonists. Br J Pharmacol (1998) 1.40
Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly(ADP-ribose) polymerase. Circ Res (2001) 1.39
Improved direct epifluorescent filter technique for rapid bioburden control in intravenous solutions. J Parenter Sci Technol (1992) 1.38
Peroxynitrite-induced thymocyte apoptosis: the role of caspases and poly (ADP-ribose) synthetase (PARS) activation. Immunology (1998) 1.34
Protection against hemorrhagic shock in mice genetically deficient in poly(ADP-ribose)polymerase. Proc Natl Acad Sci U S A (2000) 1.34
Activity of nine antimicrobial agents against Corynebacterium group D2 strains isolated from clinical specimens and skin. Antimicrob Agents Chemother (1987) 1.33
CB2 cannabinoid receptor agonists attenuate TNF-alpha-induced human vascular smooth muscle cell proliferation and migration. Br J Pharmacol (2007) 1.32
An agonist of adenosine A3 receptors decreases interleukin-12 and interferon-gamma production and prevents lethality in endotoxemic mice. Eur J Pharmacol (1998) 1.29
Biology of nitric oxide signaling. Crit Care Med (2000) 1.25
Protective effects of PJ34, a novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP) in in vitro and in vivo models of stroke. Int J Mol Med (2001) 1.24
ATP released by LPS increases nitric oxide production in raw 264.7 macrophage cell line via P2Z/P2X7 receptors. Neurochem Int (1998) 1.24
Anti-inflammatory effects of a novel, potent inhibitor of poly (ADP-ribose) polymerase. Inflamm Res (2001) 1.22
Role of poly-ADP ribosyltransferase activation in the vascular contractile and energetic failure elicited by exogenous and endogenous nitric oxide and peroxynitrite. Circ Res (1996) 1.22
Classification of coryneform bacteria associated with human urinary tract infection (group D2) as Corynebacterium urealyticum sp. nov. Int J Syst Bacteriol (1992) 1.20
Endotoxin triggers the expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in the rat aorta in vivo. FEBS Lett (1995) 1.20
Reduced oxidative and nitrosative damage in murine experimental colitis in the absence of inducible nitric oxide synthase. Gut (1999) 1.19
Poly(ADP-ribose) synthetase activation mediates mitochondrial injury during oxidant-induced cell death. J Immunol (1998) 1.18
Protective effects of mercaptoethylguanidine, a selective inhibitor of inducible nitric oxide synthase, in ligature-induced periodontitis in the rat. Br J Pharmacol (1998) 1.18
Isolation of Propionibacterium acnes from central nervous system infections. Anaerobe (1995) 1.18
Regulation of cytokine and chemokine production by transmitters and co-transmitters of the autonomic nervous system. Biochem Pharmacol (1998) 1.17