Published in Infect Immun on July 01, 2002
Protective immune mechanisms in helminth infection. Nat Rev Immunol (2007) 5.66
Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB. Proc Natl Acad Sci U S A (2009) 3.01
Immunopathology of schistosomiasis. Immunol Cell Biol (2006) 2.74
Alternatively activated macrophages in helminth infections. Curr Opin Immunol (2007) 2.41
Innate immune responses to lung-stage helminth infection induce alternatively activated alveolar macrophages. Infect Immun (2006) 1.76
Review series on helminths, immune modulation and the hygiene hypothesis: immunity against helminths and immunological phenomena in modern human populations: coevolutionary legacies? Immunology (2009) 1.64
Thioredoxin peroxidase secreted by Fasciola hepatica induces the alternative activation of macrophages. Infect Immun (2005) 1.59
Impairment of tetanus-specific cellular and humoral responses following tetanus vaccination in human lymphatic filariasis. Infect Immun (2004) 1.43
Retracted The absence of MyD88 has no effect on the induction of alternatively activated macrophage during Fasciola hepatica infection. BMC Immunol (2011) 1.40
Plasmodium falciparum and helminth coinfection in a semi urban population of pregnant women in Uganda. J Infect Dis (2008) 1.26
STAT1 is essential for antimicrobial effector function but dispensable for gamma interferon production during Toxoplasma gondii infection. Infect Immun (2004) 1.23
Similarity and diversity in macrophage activation by nematodes, trematodes, and cestodes. J Biomed Biotechnol (2010) 1.16
Parasitic helminths: new weapons against immunological disorders. J Biomed Biotechnol (2010) 1.13
Helminth infection can reduce insulitis and type 1 diabetes through CD25- and IL-10-independent mechanisms. Infect Immun (2009) 1.07
Identification of proteins differentially expressed in human monocytes exposed to Porphyromonas gingivalis and its purified components by high-throughput immunoblotting. Infect Immun (2006) 1.02
Glycoconjugates in host-helminth interactions. Front Immunol (2013) 1.01
Arginase in parasitic infections: macrophage activation, immunosuppression, and intracellular signals. J Biomed Biotechnol (2009) 0.98
Induction of alternatively activated macrophages enhances pathogenesis during severe acute respiratory syndrome coronavirus infection. J Virol (2012) 0.96
Possible role for Toll-like receptors in interaction of Fasciola hepatica excretory/secretory products with bovine macrophages. Infect Immun (2007) 0.94
Th2-associated alternative Kupffer cell activation promotes liver fibrosis without inducing local inflammation. Int J Biol Sci (2011) 0.94
Host protective roles of type 2 immunity: parasite killing and tissue repair, flip sides of the same coin. Semin Immunol (2014) 0.93
Neurocysticercosis. Ther Adv Neurol Disord (2011) 0.91
MIF homologues from a filarial nematode parasite synergize with IL-4 to induce alternative activation of host macrophages. J Leukoc Biol (2009) 0.91
Carbohydrate components of Taenia crassiceps metacestodes display Th2-adjuvant and anti-inflammatory properties when co-injected with bystander antigen. Parasitol Res (2006) 0.90
A STAT4-dependent Th1 response is required for resistance to the helminth parasite Taenia crassiceps. Infect Immun (2004) 0.88
Alternatively activated macrophages in types 1 and 2 diabetes. Mediators Inflamm (2012) 0.86
Programmed death ligand 2 regulates arginase induction and modifies Trypanosoma cruzi survival in macrophages during murine experimental infection. Immunology (2011) 0.85
TLR2 mediates immunity to experimental cysticercosis. Int J Biol Sci (2011) 0.85
Macrophage proliferation, provenance, and plasticity in macroparasite infection. Immunol Rev (2014) 0.85
Immunological interactions between 2 common pathogens, Th1-inducing protozoan Toxoplasma gondii and the Th2-inducing helminth Fasciola hepatica. PLoS One (2009) 0.85
Immunoregulation by Taenia crassiceps and its antigens. Biomed Res Int (2012) 0.84
Signal Transducers and Activators of Transcription (STAT) family members in helminth infections. Int J Biol Sci (2011) 0.82
Pathological role of large intestinal IL-12p40 for the induction of Th2-type allergic diarrhea. Am J Pathol (2004) 0.82
Cellular renewal and improvement of local cell effector activity in peritoneal cavity in response to infectious stimuli. PLoS One (2011) 0.81
Interleukin-12: an update on its immunological activities, signaling and regulation of gene expression. Curr Immunol Rev (2005) 0.80
Extraintestinal Helminth Infection Limits Pathology and Proinflammatory Cytokine Expression during DSS-Induced Ulcerative Colitis: A Role for Alternatively Activated Macrophages and Prostaglandins. Biomed Res Int (2015) 0.78
Sex-associated expression of co-stimulatory molecules CD80, CD86, and accessory molecules, PDL-1, PDL-2 and MHC-II, in F480+ macrophages during murine cysticercosis. Biomed Res Int (2013) 0.76
Helminth-induced Ly6C(hi) monocyte-derived alternatively activated macrophages suppress experimental autoimmune encephalomyelitis. Sci Rep (2017) 0.75
Differential activation of peritoneal cells by subcutaneous treatment of rats with cryptococcal antigens. Clin Vaccine Immunol (2009) 0.75
The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol Today (1996) 12.12
CD28/B7 system of T cell costimulation. Annu Rev Immunol (1996) 10.48
IL-12-deficient mice are defective in IFN gamma production and type 1 cytokine responses. Immunity (1996) 6.16
Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches. Annu Rev Immunol (1997) 5.95
The adjuvant effect of interleukin-12 in a vaccine against Leishmania major. Science (1994) 4.38
Other functions, other genes: alternative activation of antigen-presenting cells. Immunity (1999) 4.15
Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells. J Exp Med (1997) 4.06
Expression and characterization of the chemokine receptors CCR2 and CCR5 in mice. J Immunol (2001) 3.13
Concomitant infections, parasites and immune responses. Parasitology (2001) 2.68
IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells. J Immunol (1997) 2.67
Helminth infection results in decreased virus-specific CD8+ cytotoxic T-cell and Th1 cytokine responses as well as delayed virus clearance. Proc Natl Acad Sci U S A (1993) 2.65
CCR5 provides a signal for microbial induced production of IL-12 by CD8 alpha+ dendritic cells. Nat Immunol (2000) 2.49
CD8- dendritic cell activation status plays an integral role in influencing Th2 response development. J Immunol (2001) 2.42
Th1- and Th2-cell commitment during infectious disease: asymmetry in divergent pathways. Trends Immunol (2001) 2.26
Infection with Schistosoma mansoni alters Th1/Th2 cytokine responses to a non-parasite antigen. J Immunol (1992) 2.14
Alternative versus classical activation of macrophages. Pathobiology (1999) 2.14
Rapid recruitment of neutrophils containing prestored IL-12 during microbial infection. J Immunol (2000) 2.00
Alternatively activated macrophages induced by nematode infection inhibit proliferation via cell-to-cell contact. Eur J Immunol (2000) 1.78
Immunology of parasitic helminth infections. Infect Immun (2002) 1.62
Altered immune responses in mice with concomitant Schistosoma mansoni and Plasmodium chabaudi infections. Infect Immun (1998) 1.57
Proteins secreted by the parasitic nematode Nippostrongylus brasiliensis act as adjuvants for Th2 responses. Eur J Immunol (2000) 1.49
Induction of Th2 responses and IgE is largely due to carbohydrates functioning as adjuvants on Schistosoma mansoni egg antigens. J Immunol (1999) 1.47
Costimulation through B7-2 (CD86) is required for the induction of a lung mucosal T helper cell 2 (TH2) immune response and altered airway responsiveness. J Exp Med (1997) 1.44
Antigen-presenting cells recruited by Brugia malayi induce Th2 differentiation of naïve CD4(+) T cells. Eur J Immunol (2000) 1.33
Mice infected with the larvae of Taenia crassiceps exhibit a Th2-like immune response with concomitant anergy and downregulation of Th1-associated phenomena. Parasitology (1996) 1.30
Increase of CCR1 and CCR5 expression and enhanced functional response to MIP-1 alpha during differentiation of human monocytes to macrophages. J Leukoc Biol (2001) 1.30
Shift from an early protective Th1-type immune response to a late permissive Th2-type response in murine cysticercosis (Taenia crassiceps). J Parasitol (1998) 1.25
Prostaglandin E2 selectively enhances the IgE-mediated production of IL-6 and granulocyte-macrophage colony-stimulating factor by mast cells through an EP1/EP3-dependent mechanism. J Immunol (2000) 1.15
Susceptibility to Trypanosoma cruzi is modified by a previous non-related infection. Parasite Immunol (1999) 1.13
Divergent roles for macrophages in lymphatic filariasis. Parasite Immunol (2001) 1.09
Macrophage NO2- production as a sensitive and rapid assay for the quantitation of murine IFN-gamma. J Immunol Methods (1991) 1.05
Filarial antigens impair the function of human dendritic cells during differentiation. Infect Immun (2001) 1.05
Kupffer cells from Schistosoma mansoni-infected mice participate in the prompt type 2 differentiation of hepatic T cells in response to worm antigens. J Immunol (1999) 1.05
Role of IL-6 in directing the initial immune response to schistosome eggs. J Immunol (2000) 1.05
Requirement for in vivo production of IL-4, but not IL-10, in the induction of proliferative suppression by filarial parasites. J Immunol (1998) 0.99
Cutting edge: susceptibility to the larval stage of the helminth parasite Taenia crassiceps is mediated by Th2 response induced via STAT6 signaling. J Immunol (2002) 0.99
T cells and dendritic cells get intimate. Science (1999) 0.95
IL-12 as well as IL-2 upregulates CCR5 expression on T cell receptor-triggered human CD4+ and CD8+ T cells. J Clin Immunol (2001) 0.93
Effects of blocking B7-1 and B7-2 interactions during a type 2 in vivo immune response. J Immunol (1997) 0.92
IL-12 plays a pivotal role in LFA-1-mediated T cell adhesiveness by up-regulation of CCR5 expression. J Leukoc Biol (2001) 0.90
Regulation of IL-12 production by human monocytes and the influence of prostaglandin E2. Ann N Y Acad Sci (1996) 0.90
Suppressive antigen-presenting cells in Helminth infection. Pathobiology (1999) 0.90
Regulation of macrophage interleukin-6 (IL-6) and IL-10 expression by prostaglandin E2: the role of p38 mitogen-activated protein kinase. J Interferon Cytokine Res (2000) 0.89
Dendritic cells pulsed with unfractionated helminthic proteins to generate antiparasitic cytotoxic T lymphocyte. Parasite Immunol (2001) 0.88
H. polygyrus: B7-independence of the secondary type 2 response. Exp Parasitol (1996) 0.88
Suppression of macrophage interleukin-12 and tumour necrosis factor-alpha production in mice infected with Toxocara canis. Parasite Immunol (2001) 0.88
Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells. Science (2002) 8.34
Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes. Blood (2013) 4.17
Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells. J Exp Med (2002) 2.28
Toll-like receptor (TLR)-2 and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury. J Neurochem (2007) 1.92
The composition and signaling of the IL-35 receptor are unconventional. Nat Immunol (2012) 1.63
Visceral adipose inflammation in obesity is associated with critical alterations in tregulatory cell numbers. PLoS One (2011) 1.60
Interleukin-27R (WSX-1/T-cell cytokine receptor) gene-deficient mice display enhanced resistance to leishmania donovani infection but develop severe liver immunopathology. Am J Pathol (2006) 1.57
A unique mechanism for innate cytokine promotion of T cell responses to viral infections. J Immunol (2002) 1.53
Expression and localization of hepcidin in macrophages: a role in host defense against tuberculosis. J Leukoc Biol (2007) 1.46
Catechol-O-methyltransferase gene haplotypes in Mexican and Spanish patients with fibromyalgia. Arthritis Res Ther (2007) 1.36
miR-29ab1 deficiency identifies a negative feedback loop controlling Th1 bias that is dysregulated in multiple sclerosis. J Immunol (2012) 1.35
T-cell costimulation protects obesity-induced adipose inflammation and insulin resistance. Diabetes (2013) 1.27
Macrophage migration inhibitory factor deficiency impairs atherosclerosis in low-density lipoprotein receptor-deficient mice. Circulation (2004) 1.25
Cutting edge: the SLAM family receptor Ly108 controls T cell and neutrophil functions. J Immunol (2005) 1.21
Defective B cell responses in the absence of SH2D1A. Proc Natl Acad Sci U S A (2005) 1.21
CXCR3-/- mice mount an efficient Th1 response but fail to control Leishmania major infection. Eur J Immunol (2005) 1.20
The story behind the acute-phase reactants. J Rheumatol (2010) 1.16
Presence of antibodies against cyclic citrullinated peptides in patients with 'rhupus': a cross-sectional study. Arthritis Res Ther (2006) 1.13
A potential role for dendritic cell/macrophage-expressing DPP4 in obesity-induced visceral inflammation. Diabetes (2012) 1.13
IFN-gamma and STAT1 are required for efficient induction of CXC chemokine receptor 3 (CXCR3) on CD4+ but not CD8+ T cells. Blood (2007) 1.10
Cutting edge: inducible costimulator protein regulates both Th1 and Th2 responses to cutaneous leishmaniasis. J Immunol (2002) 1.10
The iron export protein ferroportin 1 is differentially expressed in mouse macrophage populations and is present in the mycobacterial-containing phagosome. J Leukoc Biol (2008) 1.10
Cutting edge: macrophage migration inhibitory factor is necessary for progression of experimental autoimmune encephalomyelitis. J Immunol (2005) 1.08
Macrophage migration inhibitory factor plays a critical role in mediating protection against the helminth parasite Taenia crassiceps. Infect Immun (2003) 1.07
Cutting edge: STAT1 and T-bet play distinct roles in determining outcome of visceral leishmaniasis caused by Leishmania donovani. J Immunol (2006) 1.06
Macrophage migration inhibitory factor contributes to host defense against acute Trypanosoma cruzi infection. Infect Immun (2006) 1.05
Mechanisms of immune evasion in leishmaniasis. Adv Appl Microbiol (2013) 1.04
Role of chemokines in regulation of immunity against leishmaniasis. Exp Parasitol (2010) 1.04
Macrophage migration inhibitory factor (MIF) is critical for the host resistance against Toxoplasma gondii. FASEB J (2008) 1.04
Role of STAT1, NF-kappaB, and C/EBPbeta in the macrophage transcriptional regulation of hepcidin by mycobacterial infection and IFN-gamma. J Leukoc Biol (2009) 1.02
Modulation of dendritic cell responses by parasites: a common strategy to survive. J Biomed Biotechnol (2010) 1.02
Critical role for phosphoinositide 3-kinase gamma in parasite invasion and disease progression of cutaneous leishmaniasis. Proc Natl Acad Sci U S A (2012) 1.00
Macrophage migration inhibitory factor potentiates autoimmune-mediated neuroinflammation. J Immunol (2013) 1.00
Variations in circulating cytokine levels during 52 week course of treatment with SSRI for major depressive disorder. Eur Neuropsychopharmacol (2008) 1.00
Macrophage migration inhibitory factor is a therapeutic target in treatment of non-insulin-dependent diabetes mellitus. FASEB J (2010) 0.99
Cutting edge: susceptibility to the larval stage of the helminth parasite Taenia crassiceps is mediated by Th2 response induced via STAT6 signaling. J Immunol (2002) 0.99
Impaired pro-inflammatory cytokine production and increased Th2-biasing ability of dendritic cells exposed to Taenia excreted/secreted antigens: A critical role for carbohydrates but not for STAT6 signaling. Int J Parasitol (2010) 0.99
Macrophage migration inhibitory factor (MIF) plays a critical role in pathogenesis of ultraviolet-B (UVB) -induced nonmelanoma skin cancer (NMSC). FASEB J (2008) 0.98
Genetic background influences immune responses and disease outcome of cutaneous L. mexicana infection in mice. Int Immunol (2005) 0.98
Leishmania inhibits STAT1-mediated IFN-gamma signaling in macrophages: increased tyrosine phosphorylation of dominant negative STAT1beta by Leishmania mexicana. Int J Parasitol (2004) 0.97
A patient presenting with diffuse cutaneous leishmaniasis (DCL) as a first indicator of HIV infection in India. Am J Trop Med Hyg (2011) 0.97
Acute cysticercosis favours rapid and more severe lesions caused by Leishmania major and Leishmania mexicana infection, a role for alternatively activated macrophages. Cell Immunol (2006) 0.96
Development of protective immunity against cutaneous leishmaniasis is dependent on STAT1-mediated IFN signaling pathway. Eur J Immunol (2003) 0.96
Depletion with PC61 mAb before Toxoplasma gondii infection eliminates mainly Tregs in BALB/c mice, but activated cells in C57BL/6J mice. FEMS Immunol Med Microbiol (2011) 0.96
Nitric oxide contributes to host resistance against experimental Taenia crassiceps cysticercosis. Parasitol Res (2007) 0.96
Helminth-excreted/secreted products are recognized by multiple receptors on DCs to block the TLR response and bias Th2 polarization in a cRAF dependent pathway. FASEB J (2013) 0.95
Pulmonary T cell activation in response to chronic particulate air pollution. Am J Physiol Lung Cell Mol Physiol (2011) 0.95
Th2-associated alternative Kupffer cell activation promotes liver fibrosis without inducing local inflammation. Int J Biol Sci (2011) 0.94
The unexpected role for the aryl hydrocarbon receptor on susceptibility to experimental toxoplasmosis. J Biomed Biotechnol (2010) 0.94
Sex hormones and modulation of immunity against leishmaniasis. Neuroimmunomodulation (2009) 0.94
Taenia crassiceps infection abrogates experimental autoimmune encephalomyelitis. Cell Immunol (2010) 0.94
A small-molecule inhibitor of macrophage migration inhibitory factor for the treatment of inflammatory disease. FASEB J (2010) 0.93
Cestode antigens induce a tolerogenic-like phenotype and inhibit LPS inflammatory responses in human dendritic cells. Int J Biol Sci (2011) 0.93
The role of interleukin-1, interleukin-6, and glia in inducing growth of neuronal terminal arbors in mice. J Neurosci (2002) 0.92
Taenia crassiceps infection attenuates multiple low-dose streptozotocin-induced diabetes. J Biomed Biotechnol (2010) 0.92
Early removal of alternatively activated macrophages leads to Taenia crassiceps cysticercosis clearance in vivo. Int J Parasitol (2010) 0.92
CXCR3-dependent CD4⁺ T cells are required to activate inflammatory monocytes for defense against intestinal infection. PLoS Pathog (2013) 0.91
C-reactive protein and complement components but not other acute-phase reactants discriminate between clinical subsets and organ damage in systemic lupus erythematosus. Clin Lab (2011) 0.90
Carbohydrate components of Taenia crassiceps metacestodes display Th2-adjuvant and anti-inflammatory properties when co-injected with bystander antigen. Parasitol Res (2006) 0.90
Toxoplasma gondii: impaired maturation and pro-inflammatory response of dendritic cells in MIF-deficient mice favors susceptibility to infection. Exp Parasitol (2010) 0.90
Acute pyelonephritis in renal allografts: a new role for microRNAs? Transplantation (2014) 0.90
Macrophage migration inhibitory factor plays a role in the regulation of microfold (M) cell-mediated transport in the gut. J Immunol (2008) 0.90
Reduction of Foxp3+ cells by depletion with the PC61 mAb induces mortality in resistant BALB/c mice infected with Toxoplasma gondii. J Biomed Biotechnol (2009) 0.89
Differential response of antigen presenting cells from susceptible and resistant strains of mice to Taenia crassiceps infection. Infect Genet Evol (2009) 0.89
Heat, Oriental sore, and HIV. Lancet (2011) 0.88
A STAT4-dependent Th1 response is required for resistance to the helminth parasite Taenia crassiceps. Infect Immun (2004) 0.88
CXCR3 deficiency enhances tumor progression by promoting macrophage M2 polarization in a murine breast cancer model. Immunology (2014) 0.88
Mammalian antimicrobial peptide influences control of cutaneous Leishmania infection. Cell Microbiol (2011) 0.88
Differential effect of sodium arsenite during the activation of human CD4+ and CD8+ T lymphocytes. Int Immunopharmacol (2005) 0.88
Francisella inhibits STAT1-mediated signaling in macrophages and prevents activation of antigen-specific T cells. Int Immunol (2008) 0.88
A new highly effective anticysticercosis vaccine expressed in transgenic papaya. Vaccine (2007) 0.88
Cytokines and their STATs in cutaneous and visceral leishmaniasis. J Biomed Biotechnol (2010) 0.87
T helper differentiation in resistant and susceptible B7-deficient mice infected with Leishmania major. Eur J Immunol (2002) 0.87
Multilocus microsatellite signature and identification of specific molecular markers for Leishmania aethiopica. Parasit Vectors (2013) 0.86
Role of phosphatidylinositol-3-kinase-gamma (PI3Kgamma)-mediated pathway in 17beta-estradiol-induced killing of L. mexicana in macrophages from C57BL/6 mice. Immunol Cell Biol (2008) 0.86
Alternatively activated macrophages in types 1 and 2 diabetes. Mediators Inflamm (2012) 0.86
Lack of CXCR3 delays the development of hepatic inflammation but does not impair resistance to Leishmania donovani. J Infect Dis (2007) 0.86
Sodium arsenite retards proliferation of PHA-activated T cells by delaying the production and secretion of IL-2. Int Immunopharmacol (2003) 0.86
Leishmanicidal activity of racemic +/- 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4-methyl-5-[3,4-dichlorophenoxy]quinoline. Nat Prod Commun (2010) 0.86
Macrophage migration inhibitory factor (MIF) is essential for inflammatory and neuropathic pain and enhances pain in response to stress. Exp Neurol (2012) 0.86
Mechanisms of cellular invasion by intracellular parasites. Cell Mol Life Sci (2013) 0.86
Conundrum of pathogenesis of diabetic cardiomyopathy: role of vascular endothelial dysfunction, reactive oxygen species, and mitochondria. Mol Cell Biochem (2013) 0.85
Clinco-epidemiologic study of cutaneous leishmaniasis in Bikaner, Rajasthan, India. Am J Trop Med Hyg (2013) 0.85
TLR2 mediates immunity to experimental cysticercosis. Int J Biol Sci (2011) 0.85
Immunoregulation by Taenia crassiceps and its antigens. Biomed Res Int (2012) 0.84