Published in Arterioscler Thromb Vasc Biol on June 01, 2002
Low-dose irradiation promotes tissue revascularization through VEGF release from mast cells and MMP-9-mediated progenitor cell mobilization. J Exp Med (2005) 1.93
PPAR alpha inhibits vascular smooth muscle cell proliferation underlying intimal hyperplasia by inducing the tumor suppressor p16INK4a. J Clin Invest (2005) 1.58
Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation. Biochem J (2007) 1.49
Intimal hyperplasia in murine models. Curr Drug Targets (2008) 1.22
Inactivation of the tumour suppressor, PTEN, in smooth muscle promotes a pro-inflammatory phenotype and enhances neointima formation. Cardiovasc Res (2010) 1.14
Mouse models of arteriosclerosis: from arterial injuries to vascular grafts. Am J Pathol (2004) 1.13
Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans. J Clin Invest (2010) 1.09
Glutathione S-transferase-micro1 regulates vascular smooth muscle cell proliferation, migration, and oxidative stress. Hypertension (2009) 1.08
Protein kinase A-regulated assembly of a MEF2{middle dot}HDAC4 repressor complex controls c-Jun expression in vascular smooth muscle cells. J Biol Chem (2009) 1.08
Id3 is a novel atheroprotective factor containing a functionally significant single-nucleotide polymorphism associated with intima-media thickness in humans. Circ Res (2010) 1.07
Smooth muscle LDL receptor-related protein-1 inactivation reduces vascular reactivity and promotes injury-induced neointima formation. Arterioscler Thromb Vasc Biol (2009) 1.03
Regulation of smooth muscle by inducible nitric oxide synthase and NADPH oxidase in vascular proliferative diseases. Free Radic Biol Med (2008) 1.03
Quantitative trait locus analysis of neointimal formation in an intercross between C57BL/6 and C3H/HeJ apolipoprotein E-deficient mice. Circ Cardiovasc Genet (2009) 1.02
Nf1+/- mice have increased neointima formation via hyperactivation of a Gleevec sensitive molecular pathway. Hum Mol Genet (2008) 1.01
Apolipoprotein E inhibition of vascular hyperplasia and neointima formation requires inducible nitric oxide synthase. J Lipid Res (2005) 0.98
Interferon regulatory factor 8 modulates phenotypic switching of smooth muscle cells by regulating the activity of myocardin. Mol Cell Biol (2013) 0.88
Sphingosine-1-phosphate receptor 3 promotes neointimal hyperplasia in mouse iliac-femoral arteries. Arterioscler Thromb Vasc Biol (2012) 0.87
Comparative genetics of atherosclerosis and restenosis: exploration with mouse models. Arterioscler Thromb Vasc Biol (2002) 0.87
Vascular apolipoprotein e expression and recruitment from circulation to modulate smooth muscle cell response to endothelial denudation. Am J Pathol (2004) 0.87
Morelloflavone blocks injury-induced neointimal formation by inhibiting vascular smooth muscle cell migration. Biochim Biophys Acta (2008) 0.86
Genetic variants of ApoE and ApoER2 differentially modulate endothelial function. Proc Natl Acad Sci U S A (2014) 0.85
IL-19 reduces ligation-mediated neointimal hyperplasia by reducing vascular smooth muscle cell activation. Am J Pathol (2014) 0.83
3,3'Diindolylmethane suppresses vascular smooth muscle cell phenotypic modulation and inhibits neointima formation after carotid injury. PLoS One (2012) 0.80
Unique remodeling processes after vascular injury in intracranial arteries: analysis using a novel mouse model. J Cereb Blood Flow Metab (2013) 0.79
Genetic determinants of atherosclerosis, obesity, and energy balance in consomic mice. Mamm Genome (2014) 0.77
Interferon regulatory factor 7 protects against vascular smooth muscle cell proliferation and neointima formation. J Am Heart Assoc (2014) 0.77
A murine model of arterial restenosis: technical aspects of femoral wire injury. J Vis Exp (2015) 0.75
Nf1+/- monocytes/macrophages induce neointima formation via CCR2 activation. Hum Mol Genet (2016) 0.75
Genetic analysis of ligation-induced neointima formation in an F2 intercross of C57BL/6 and FVB/N inbred mouse strains. PLoS One (2015) 0.75
Obesity-associated improvements in metabolic profile through expansion of adipose tissue. J Clin Invest (2007) 8.71
Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis. J Clin Invest (2003) 4.08
The central melanocortin system directly controls peripheral lipid metabolism. J Clin Invest (2007) 2.97
Triglyceride-rich lipoproteins prime aortic endothelium for an enhanced inflammatory response to tumor necrosis factor-alpha. Circ Res (2007) 2.83
Leukocyte engagement of fibrin(ogen) via the integrin receptor alphaMbeta2/Mac-1 is critical for host inflammatory response in vivo. J Clin Invest (2004) 2.57
Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice. J Clin Invest (2010) 1.90
Myeloid-specific Krüppel-like factor 2 inactivation increases macrophage and neutrophil adhesion and promotes atherosclerosis. Circ Res (2012) 1.84
An analysis of the role of a retroendocytosis pathway in ABCA1-mediated cholesterol efflux from macrophages. J Lipid Res (2008) 1.78
Prevalence and outcome of allergic colitis in healthy infants with rectal bleeding: a prospective cohort study. J Pediatr Gastroenterol Nutr (2005) 1.78
An ACE inhibitor reduces Th2 cytokines and TGF-beta1 and TGF-beta2 isoforms in murine lupus nephritis. Kidney Int (2004) 1.76
Adipocyte LDL receptor-related protein-1 expression modulates postprandial lipid transport and glucose homeostasis in mice. J Clin Invest (2007) 1.73
Fibrin(ogen) exacerbates inflammatory joint disease through a mechanism linked to the integrin alphaMbeta2 binding motif. J Clin Invest (2007) 1.52
Differential contribution of IL-4 and STAT6 vs STAT4 to the development of lupus nephritis. J Immunol (2003) 1.47
Class B type I scavenger receptor is responsible for the high affinity cholesterol binding activity of intestinal brush border membrane vesicles. Biochim Biophys Acta (2007) 1.38
Protection against diet-induced obesity and obesity- related insulin resistance in Group 1B PLA2-deficient mice. Am J Physiol Endocrinol Metab (2002) 1.30
Gaucher disease mouse models: point mutations at the acid beta-glucosidase locus combined with low-level prosaposin expression lead to disease variants. J Lipid Res (2005) 1.27
Group 1B phospholipase A2-mediated lysophospholipid absorption directly contributes to postprandial hyperglycemia. Diabetes (2006) 1.27
Defective lipid delivery modulates glucose tolerance and metabolic response to diet in apolipoprotein E-deficient mice. Diabetes (2007) 1.27
Small noncoding differentially methylated copy-number variants, including lncRNA genes, cause a lethal lung developmental disorder. Genome Res (2012) 1.26
Cancer-selective targeting and cytotoxicity by liposomal-coupled lysosomal saposin C protein. Clin Cancer Res (2009) 1.26
Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1-/- mice. Am J Physiol Gastrointest Liver Physiol (2008) 1.26
Neuronopathic Gaucher disease in the mouse: viable combined selective saposin C deficiency and mutant glucocerebrosidase (V394L) mice with glucosylsphingosine and glucosylceramide accumulation and progressive neurological deficits. Hum Mol Genet (2010) 1.25
DNA microarray analysis reveals novel gene expression profiles in collagen-induced arthritis. Clin Immunol (2002) 1.25
Melanocortin signaling in the CNS directly regulates circulating cholesterol. Nat Neurosci (2010) 1.25
Laser capture microdissection-microarray analysis of focal segmental glomerulosclerosis glomeruli. Nephron Exp Nephrol (2007) 1.24
Colitis-associated cancer is dependent on the interplay between the hemostatic and inflammatory systems and supported by integrin alpha(M)beta(2) engagement of fibrinogen. Cancer Res (2010) 1.21
Histone deacetylase 9 is a negative regulator of adipogenic differentiation. J Biol Chem (2011) 1.20
Expression and regulation of a disintegrin and metalloproteinase (ADAM) 8 in experimental asthma. Am J Respir Cell Mol Biol (2004) 1.19
Epstein-Barr virus-related bilateral acute retinal necrosis in a patient with X-linked lymphoproliferative disorder. Arch Ophthalmol (2003) 1.19
Targeted inactivation of the mouse guanylin gene results in altered dynamics of colonic epithelial proliferation. Am J Pathol (2002) 1.18
Negative regulation of eosinophil recruitment to the lung by the chemokine monokine induced by IFN-gamma (Mig, CXCL9). Proc Natl Acad Sci U S A (2004) 1.18
The role of apolipoprotein A-I helix 10 in apolipoprotein-mediated cholesterol efflux via the ATP-binding cassette transporter ABCA1. J Biol Chem (2002) 1.16
DEK proto-oncogene expression interferes with the normal epithelial differentiation program. Am J Pathol (2008) 1.15
Expression and regulation of small proline-rich protein 2 in allergic inflammation. Am J Respir Cell Mol Biol (2005) 1.11
Genetic elimination of prothrombin in adult mice is not compatible with survival and results in spontaneous hemorrhagic events in both heart and brain. Blood (2008) 1.11
Apolipoprotein J/clusterin prevents a progressive glomerulopathy of aging. Mol Cell Biol (2002) 1.09
HDAC9 knockout mice are protected from adipose tissue dysfunction and systemic metabolic disease during high-fat feeding. Diabetes (2013) 1.07
Lack of association between adiponectin levels and atherosclerosis in mice. Arterioscler Thromb Vasc Biol (2010) 1.07
The Na,K-ATPase alpha 2 isoform is expressed in neurons, and its absence disrupts neuronal activity in newborn mice. J Biol Chem (2002) 1.04
The role of the receptor tyrosine kinase Ron in nickel-induced acute lung injury. Am J Respir Cell Mol Biol (2002) 1.04
Postprandial lysophospholipid suppresses hepatic fatty acid oxidation: the molecular link between group 1B phospholipase A2 and diet-induced obesity. FASEB J (2010) 1.03
Smooth muscle LDL receptor-related protein-1 inactivation reduces vascular reactivity and promotes injury-induced neointima formation. Arterioscler Thromb Vasc Biol (2009) 1.03
Microarray analysis of novel cell lines representing two stages of metanephric mesenchyme differentiation. Mech Dev (2002) 1.02
Ginsenoside Rb1 reduces fatty liver by activating AMP-activated protein kinase in obese rats. J Lipid Res (2013) 1.01
The fanconi anemia pathway limits human papillomavirus replication. J Virol (2012) 1.01
Saposin C-LBPA interaction in late-endosomes/lysosomes. Exp Cell Res (2005) 1.01
Bile salt-stimulated carboxyl ester lipase influences lipoprotein assembly and secretion in intestine: a process mediated via ceramide hydrolysis. J Biol Chem (2001) 1.01
Posterior distal femoral and proximal tibial metaphyseal stripes at MR imaging in children and young adults. Radiology (2002) 1.01
Pancreatic triglyceride lipase deficiency minimally affects dietary fat absorption but dramatically decreases dietary cholesterol absorption in mice. J Biol Chem (2003) 1.00
Carboxyl ester lipase expression in macrophages increases cholesteryl ester accumulation and promotes atherosclerosis. J Biol Chem (2005) 1.00
Lipoprotein receptors in the vascular wall. Curr Opin Lipidol (2004) 0.99
Low density lipoprotein receptor-related protein mediates apolipoprotein E inhibition of smooth muscle cell migration. J Biol Chem (2001) 0.99
Microarray-based discovery of highly expressed olfactory mucosal genes: potential roles in the various functions of the olfactory system. Physiol Genomics (2003) 0.99
Neurological deficits and glycosphingolipid accumulation in saposin B deficient mice. Hum Mol Genet (2008) 0.99
Both apolipoprotein E and immune deficiency exacerbate neointimal hyperplasia after vascular injury in mice. Arterioscler Thromb Vasc Biol (2002) 0.98
The role of mannosylated enzyme and the mannose receptor in enzyme replacement therapy. Am J Hum Genet (2005) 0.98
Apolipoprotein E inhibition of vascular hyperplasia and neointima formation requires inducible nitric oxide synthase. J Lipid Res (2005) 0.98
Apolipoprotein E binding to low density lipoprotein receptor-related protein-1 inhibits cell migration via activation of cAMP-dependent protein kinase A. J Biol Chem (2003) 0.97
Plasminogen supports tumor growth through a fibrinogen-dependent mechanism linked to vascular patency. Blood (2003) 0.97
Specific saposin C deficiency: CNS impairment and acid beta-glucosidase effects in the mouse. Hum Mol Genet (2009) 0.97
Neural system-enriched gene expression: relationship to biological pathways and neurological diseases. Physiol Genomics (2004) 0.96
Hepatic deficiency of low density lipoprotein receptor-related protein-1 reduces high density lipoprotein secretion and plasma levels in mice. J Biol Chem (2011) 0.96
Distinct apolipoprotein E isoform preference for inhibition of smooth muscle cell migration and proliferation. Biochemistry (2002) 0.96
Carboxyl ester lipase deficiency exacerbates dietary lipid absorption abnormalities and resistance to diet-induced obesity in pancreatic triglyceride lipase knockout mice. J Biol Chem (2007) 0.95
Microarray analysis of focal segmental glomerulosclerosis. Am J Nephrol (2004) 0.94
Engineering a lysosomal enzyme with a derivative of receptor-binding domain of apoE enables delivery across the blood-brain barrier. Proc Natl Acad Sci U S A (2013) 0.94
Combined saposin C and D deficiencies in mice lead to a neuronopathic phenotype, glucosylceramide and alpha-hydroxy ceramide accumulation, and altered prosaposin trafficking. Hum Mol Genet (2007) 0.94
Apolipoprotein E4 impairs macrophage efferocytosis and potentiates apoptosis by accelerating endoplasmic reticulum stress. J Biol Chem (2012) 0.93
Human coronary artery perivascular adipocytes overexpress genes responsible for regulating vascular morphology, inflammation, and hemostasis. Physiol Genomics (2013) 0.93
Prosaposin: threshold rescue and analysis of the "neuritogenic" region in transgenic mice. Mol Genet Metab (2002) 0.92
Group 1B phospholipase A₂ deficiency protects against diet-induced hyperlipidemia in mice. J Lipid Res (2011) 0.92
Obesity and extreme obesity, manifest by ages 20-24 years, continuing through 32-41 years in women, should alert physicians to the diagnostic likelihood of polycystic ovary syndrome as a reversible underlying endocrinopathy. Eur J Obstet Gynecol Reprod Biol (2005) 0.91
Emergence and compartmentalization of fatal multi-drug-resistant cytomegalovirus infection in a patient with autosomal-recessive severe combined immune deficiency. J Pediatr Hematol Oncol (2004) 0.90
Spermidine/spermine-N1-acetyltransferase ablation protects against liver and kidney ischemia-reperfusion injury in mice. Am J Physiol Gastrointest Liver Physiol (2009) 0.90
Leptin replacement therapy but not dietary polyunsaturated fatty acid alleviates HIV protease inhibitor-induced dyslipidemia and lipodystrophy in mice. J Acquir Immune Defic Syndr (2003) 0.88
Microarray analysis of novel cell lines representing two stages of metanephric mesenchyme differentiation. Mech Dev (2002) 0.88
Lysosomal acid lipase deficiency: correction of lipid storage by adenovirus-mediated gene transfer in mice. Hum Gene Ther (2002) 0.88
Apolipoprotein E inhibits toll-like receptor (TLR)-3- and TLR-4-mediated macrophage activation through distinct mechanisms. Biochem J (2010) 0.88
The chemopreventive action of equol enantiomers in a chemically induced animal model of breast cancer. Carcinogenesis (2010) 0.88
Apolipoprotein E does not cross the blood-cerebrospinal fluid barrier, as revealed by an improved technique for sampling CSF from mice. Am J Physiol Regul Integr Comp Physiol (2012) 0.87
Fetal surgical management of congenital heart block in a hydropic fetus: lessons learned from a clinical experience. J Thorac Cardiovasc Surg (2010) 0.87
MLK3 promotes metabolic dysfunction induced by saturated fatty acid-enriched diet. Am J Physiol Endocrinol Metab (2013) 0.87
Vascular apolipoprotein e expression and recruitment from circulation to modulate smooth muscle cell response to endothelial denudation. Am J Pathol (2004) 0.87
Lack of guanylyl cyclase C, the receptor for Escherichia coli heat-stable enterotoxin, results in reduced polyp formation and increased apoptosis in the multiple intestinal neoplasia (Min) mouse model. Int J Cancer (2005) 0.86
Morelloflavone blocks injury-induced neointimal formation by inhibiting vascular smooth muscle cell migration. Biochim Biophys Acta (2008) 0.86
Nonproteolytic properties of murine alternatively spliced tissue factor: implications for integrin-mediated signaling in murine models. Mol Med (2012) 0.85
Apolipoprotein E2 accentuates postprandial inflammation and diet-induced obesity to promote hyperinsulinemia in mice. Diabetes (2012) 0.85
Developmental expression of Magmas in murine tissues and its co-expression with the GM-CSF receptor. J Histochem Cytochem (2003) 0.85
Rescue of prothrombin-deficiency by transgene expression in mice. Thromb Haemost (2002) 0.85
The receptor binding domain of apolipoprotein E is responsible for its antioxidant activity. Biochemistry (2005) 0.85
Cytomegalovirus and recurrent idiopathic membranoproliferative glomerulonephritis type 1: cause or consequence? Transplantation (2007) 0.83
Reduction of atherosclerotic plaques by lysosomal acid lipase supplementation. Arterioscler Thromb Vasc Biol (2003) 0.83
Temporal gene expression profiling reveals CEBPD as a candidate regulator of brain disease in prosaposin deficient mice. BMC Neurosci (2008) 0.83
Carboxyl ester lipase cofractionates with scavenger receptor BI in hepatocyte lipid rafts and enhances selective uptake and hydrolysis of cholesteryl esters from HDL3. J Biol Chem (2004) 0.83
The APC tumor suppressor is required for epithelial integrity in the mouse mammary gland. J Cell Physiol (2009) 0.82
Metabolic control by S6 kinases depends on dietary lipids. PLoS One (2012) 0.82
The factor V Leiden mutation, high factor VIII, and high plasminogen activator inhibitor activity: etiologies for sporadic miscarriage. Metabolism (2005) 0.82
Participation of ATP7A in macrophage mediated oxidation of LDL. J Lipid Res (2009) 0.82
Separation of micelles and vesicles within lumenal aspirates from healthy humans: solubilization of cholesterol after a meal. J Lipid Res (2002) 0.82