Published in Antisense Nucleic Acid Drug Dev on April 01, 2002
Twenty years of cell-penetrating peptides: from molecular mechanisms to therapeutics. Br J Pharmacol (2009) 2.99
Insight into the mechanism of the peptide-based gene delivery system MPG: implications for delivery of siRNA into mammalian cells. Nucleic Acids Res (2003) 2.34
Improved cell-penetrating peptide-PNA conjugates for splicing redirection in HeLa cells and exon skipping in mdx mouse muscle. Nucleic Acids Res (2008) 1.52
Antisense inhibition of gene expression in cells by oligonucleotides incorporating locked nucleic acids: effect of mRNA target sequence and chimera design. Nucleic Acids Res (2002) 1.52
CNS delivery via adsorptive transcytosis. AAPS J (2008) 1.46
Cell-penetrating peptide conjugates of peptide nucleic acids (PNA) as inhibitors of HIV-1 Tat-dependent trans-activation in cells. Nucleic Acids Res (2005) 1.44
Efficient splicing correction by PNA conjugation to an R6-Penetratin delivery peptide. Nucleic Acids Res (2007) 1.28
Synthesis, cellular uptake and HIV-1 Tat-dependent trans-activation inhibition activity of oligonucleotide analogues disulphide-conjugated to cell-penetrating peptides. Nucleic Acids Res (2005) 1.27
DNA-templated polymerization of side-chain-functionalized peptide nucleic acid aldehydes. J Am Chem Soc (2008) 1.18
Cationic shell-cross-linked knedel-like (cSCK) nanoparticles for highly efficient PNA delivery. Mol Pharm (2009) 1.15
Delivery of nanomedicines to extracellular and intracellular compartments of a solid tumor. Adv Drug Deliv Rev (2011) 1.11
Internalization of novel non-viral vector TAT-streptavidin into human cells. BMC Biotechnol (2007) 1.02
Subnanomolar antisense activity of phosphonate-peptide nucleic acid (PNA) conjugates delivered by cationic lipids to HeLa cells. Nucleic Acids Res (2008) 0.99
Metabolic cleavage of cell-penetrating peptides in contact with epithelial models: human calcitonin (hCT)-derived peptides, Tat(47-57) and penetratin(43-58). Biochem J (2004) 0.98
Recent developments in peptide-based nucleic acid delivery. Int J Mol Sci (2008) 0.92
Cell-penetrating peptides: achievements and challenges in application for cancer treatment. J Biomed Mater Res A (2013) 0.90
Phospholipid conjugate for intracellular delivery of peptide nucleic acids. Bioconjug Chem (2009) 0.87
Pharmacokinetic analysis of polyamide nucleic-acid-cell penetrating peptide conjugates targeted against HIV-1 transactivation response element. Oligonucleotides (2008) 0.86
TAT-mediated intracellular protein delivery to primary brain cells is dependent on glycosaminoglycan expression. Biotechnol Bioeng (2009) 0.86
LNA-based oligonucleotide electrotransfer for miRNA inhibition. Mol Ther (2012) 0.84
Design and application of multifunctional DNA nanocarriers for therapeutic delivery. Acta Biomater (2013) 0.83
Hydroxyproline-based DNA mimics provide an efficient gene silencing in vitro and in vivo. Nucleic Acids Res (2006) 0.82
Delivery of antisense peptide nucleic acids to cells by conjugation with small arginine-rich cell-penetrating peptide (R/W)9. PLoS One (2014) 0.80
Design of (Gd-DO3A)n-polydiamidopropanoyl-peptide nucleic acid-D(Cys-Ser-Lys-Cys) magnetic resonance contrast agents. Biopolymers (2008) 0.80
Prospects for antisense peptide nucleic acid (PNA) therapies for HIV. Expert Opin Biol Ther (2009) 0.79
Nanotechnology for delivery of peptide nucleic acids (PNAs). J Control Release (2016) 0.77
Cell number and transfection volume dependent peptide nucleic acid antisense activity by cationic delivery methods. Artif DNA PNA XNA (2012) 0.76
Transporter molecules influence the gene expression in HeLa cells. Int J Med Sci (2008) 0.75
DNA and RNA derivatives to optimize distribution and delivery. Adv Drug Deliv Rev (2015) 0.75
Cell Permeable Peptides: A Promising Tool to Deliver Neuroprotective Agents in the Brain. Pharmaceuticals (Basel) (2010) 0.75
Inhibition of Staphylococcus aureus gene expression and growth using antisense peptide nucleic acids. Mol Ther (2004) 2.08
Induction of adipocyte-like phenotype in human mesenchymal stem cells by hypoxia. Stem Cells (2004) 1.43
Instability of standard PCR reference genes in adipose-derived stem cells during propagation, differentiation and hypoxic exposure. BMC Mol Biol (2008) 1.41
Evaluation of cell-penetrating peptides (CPPs) as vehicles for intracellular delivery of antisense peptide nucleic acid (PNA). Bioconjug Chem (2006) 1.29
Prolonged hypoxic culture and trypsinization increase the pro-angiogenic potential of human adipose tissue-derived stem cells. Cytotherapy (2010) 1.25
Genotypic characterization of Kaposi's sarcoma-associated herpesvirus in asymptomatic infected subjects from isolated populations. J Gen Virol (2004) 1.20
Improved cellular activity of antisense peptide nucleic acids by conjugation to a cationic peptide-lipid (CatLip) domain. Bioconjug Chem (2008) 1.15
Signatures of the preagricultural peopling processes in sub-Saharan Africa as revealed by the phylogeography of early Y chromosome lineages. Mol Biol Evol (2011) 1.13
Adipose-derived stem cells from the brown bear (Ursus arctos) spontaneously undergo chondrogenic and osteogenic differentiation in vitro. Stem Cell Res (2011) 1.09
Identification of a tightly regulated hypoxia-response element in the promoter of human plasminogen activator inhibitor-1. Blood (2002) 1.06
Comparison of human adipose-derived stem cells and bone marrow-derived stem cells in a myocardial infarction model. Cell Transplant (2012) 1.03
Pericellular oxygen depletion during ordinary tissue culturing, measured with oxygen microsensors. Cell Prolif (2005) 1.03
Cell surface targeting of pregnancy-associated plasma protein A proteolytic activity. Reversible adhesion is mediated by two neighboring short consensus repeats. J Biol Chem (2002) 1.03
Development and characterization of a clinically compliant xeno-free culture medium in good manufacturing practice for human multipotent mesenchymal stem cells. Stem Cells Transl Med (2012) 1.02
Inhibition of Mycobacterium smegmatis gene expression and growth using antisense peptide nucleic acids. J Mol Microbiol Biotechnol (2005) 0.99
Comparative analysis of highly defined proteases for the isolation of adipose tissue-derived stem cells. Regen Med (2008) 0.97
Evaluation of transfection protocols for unmodified and modified peptide nucleic acid (PNA) oligomers. Oligonucleotides (2006) 0.97
Effect of growth media and serum replacements on the proliferation and differentiation of adipose-derived stem cells. Cytotherapy (2009) 0.97
Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium. J Enzyme Inhib Med Chem (2014) 0.96
DNA supercoiling enhances cooperativity and efficiency of an epigenetic switch. Proc Natl Acad Sci U S A (2013) 0.95
Activation of protease-activated receptor 2 induces VEGF independently of HIF-1. PLoS One (2012) 0.94
Defined xenogeneic-free and hypoxic environment provides superior conditions for long-term expansion of human adipose-derived stem cells. Tissue Eng Part C Methods (2012) 0.94
Adipogenic differentiation of human mesenchymal stem cells. Methods Mol Biol (2011) 0.93
Quantitative transcriptional profiling of ATDC5 mouse progenitor cells during chondrogenesis. Differentiation (2005) 0.91
Isolation and expansion of adipose-derived stem cells for tissue engineering. Front Biosci (Elite Ed) (2011) 0.90
A maternal low protein diet has pronounced effects on mitochondrial gene expression in offspring liver and skeletal muscle; protective effect of taurine. J Biomed Sci (2010) 0.89
Nanoscale topography reduces fibroblast growth, focal adhesion size and migration-related gene expression on platinum surfaces. Colloids Surf B Biointerfaces (2011) 0.89
Simultaneously amplified electrochemical and surface plasmon optical detection of DNA hybridization based on ferrocene-streptavidin conjugates. Anal Chem (2005) 0.89
Gestational protein restriction in mice has pronounced effects on gene expression in newborn offspring's liver and skeletal muscle; protective effect of taurine. Pediatr Res (2010) 0.88
Role of placental cytokines in transcriptional modulation of HIV type 1 in the isolated villous trophoblast. AIDS Res Hum Retroviruses (2002) 0.88
Transcriptional regulation of plasminogen activator inhibitor-1 expression by insulin-like growth factor-1 via MAP kinases and hypoxia-inducible factor-1 in HepG2 cells. Thromb Haemost (2005) 0.86
Mechanisms of the elimination of low dose hyper-radiosensitivity in T-47D cells by low dose-rate priming. Int J Radiat Biol (2009) 0.84
Development of cardiac support bioprostheses for ventricular restoration and myocardial regeneration. Eur J Cardiothorac Surg (2012) 0.83
Transcriptional dissection of human limbal niche compartments by massive parallel sequencing. PLoS One (2013) 0.83
Hypoxia is a key regulator of limbal epithelial stem cell growth and differentiation. Stem Cell Res (2013) 0.83
Studying health consequences of microchimerism: methodological problems in studying health effects of procreation with multiple partners. Eur J Epidemiol (2003) 0.83
A DNA minor groove electronegative potential genome map based on photo-chemical probing. Nucleic Acids Res (2011) 0.82
Temporal transcriptome of mouse ATDC5 chondroprogenitors differentiating under hypoxic conditions. Exp Cell Res (2006) 0.82
Derivation and characterization of four new human embryonic stem cell lines: the Danish experience. Reprod Biomed Online (2006) 0.81
Minimal engraftment of human CD34+ cells mobilized from healthy donors in the infarcted heart of athymic nude rats. Stem Cells Dev (2009) 0.81
Linking measured intercellular oxygen concentration to human cell functions. Acta Oncol (2004) 0.80
Cripto-1 expression in glioblastoma multiforme. Brain Pathol (2014) 0.80
PNA-DNA hybridization study using labeled streptavidin by voltammetry and surface plasmon fluorescence spectroscopy. Anal Chem (2006) 0.80
Differential patterns of human cytomegalovirus gene expression in various T-cell lines carrying human T-cell leukemia-lymphoma virus type I: role of Tax-activated cellular transcription factors. J Med Virol (2003) 0.79
Dissecting direct and indirect readout of cAMP receptor protein DNA binding using an inosine and 2,6-diaminopurine in vitro selection system. Nucleic Acids Res (2008) 0.79
Transcriptional activation of immediate-early gene ETR101 by human T-cell leukaemia virus type I Tax. J Gen Virol (2003) 0.79
Patterned polymeric surfaces to study the influence of nanotopography on the growth and differentiation of mesenchymal stem cells. Methods Mol Biol (2013) 0.79
Hypoxia enhances chondrogenic differentiation of human adipose tissue-derived stromal cells in scaffold-free and scaffold systems. Cell Tissue Res (2013) 0.78
Patterned poly(lactic acid) films support growth and spontaneous multilineage gene expression of adipose-derived stem cells. Colloids Surf B Biointerfaces (2011) 0.78
Elliptical posts allow for detailed control of non-equibiaxial straining of cell cultures. J Tissue Viability (2013) 0.78
Optimized chondrogenesis of ATCD5 cells through sequential regulation of oxygen conditions. Tissue Eng (2006) 0.78
Uniaxial cyclic strain drives assembly and differentiation of skeletal myocytes. Tissue Eng Part A (2011) 0.78
Phosphate selective uranyl photo-affinity cleavage of proteins. Determination of phosphorylation sites. Chembiochem (2008) 0.77
Human herpesvirus 6 variant a infects human term syncytiotrophoblasts in vitro and induces replication of human immunodeficiency virus type 1 in dually infected cells. J Med Virol (2002) 0.77
Targeted antiepidermal growth factor receptor (cetuximab) immunoliposomes enhance cellular uptake in vitro and exhibit increased accumulation in an intracranial model of glioblastoma multiforme. J Drug Deliv (2013) 0.76
Triple helix stabilization by covalently linked DNA-bisbenzimidazole conjugate synthesized by maleimide-thiol coupling chemistry. Bioorg Med Chem (2006) 0.75
The influence of surface properties of plasma-etched polydimethylsiloxane (PDMS) on cell growth and morphology. Conf Proc IEEE Eng Med Biol Soc (2010) 0.75
A novel indirect sequence readout component in the E. coli cyclic AMP receptor protein operator. ACS Chem Biol (2014) 0.75
Hypoxic treatment inhibits insulin-induced chondrogenesis of ATDC5 cells despite upregulation of DEC1. Connect Tissue Res (2006) 0.75