Published in Trends Cell Biol on June 01, 2002
Adaptation of core mechanisms to generate cell polarity. Nature (2003) 5.64
Central roles of small GTPases in the development of cell polarity in yeast and beyond. Microbiol Mol Biol Rev (2007) 3.30
ARF6 controls post-endocytic recycling through its downstream exocyst complex effector. J Cell Biol (2003) 2.02
Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase. EMBO J (2005) 1.75
Ral-regulated interaction between Sec5 and paxillin targets Exocyst to focal complexes during cell migration. J Cell Sci (2008) 1.68
RalA but not RalB enhances polarized delivery of membrane proteins to the basolateral surface of epithelial cells. Mol Cell Biol (2004) 1.59
SEC8, a subunit of the putative Arabidopsis exocyst complex, facilitates pollen germination and competitive pollen tube growth. Plant Physiol (2005) 1.51
Lethal giant larvae proteins interact with the exocyst complex and are involved in polarized exocytosis. J Cell Biol (2005) 1.47
Structural basis of the interaction between RalA and Sec5, a subunit of the sec6/8 complex. EMBO J (2003) 1.43
Cyclical regulation of the exocyst and cell polarity determinants for polarized cell growth. Mol Biol Cell (2005) 1.42
Syntaxin 3 and SNAP-25 pairing, regulated by omega-3 docosahexaenoic acid, controls the delivery of rhodopsin for the biogenesis of cilia-derived sensory organelles, the rod outer segments. J Cell Sci (2009) 1.39
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Exo70p mediates the secretion of specific exocytic vesicles at early stages of the cell cycle for polarized cell growth. J Cell Biol (2007) 1.31
Rab13 regulates membrane trafficking between TGN and recycling endosomes in polarized epithelial cells. J Cell Biol (2008) 1.30
Ectopic expression of an activated RAC in Arabidopsis disrupts membrane cycling. Mol Biol Cell (2005) 1.22
Discs-Large and Strabismus are functionally linked to plasma membrane formation. Nat Cell Biol (2003) 1.22
Phosphoinositides, ezrin/moesin, and rac1 regulate fusion of rhodopsin transport carriers in retinal photoreceptors. Mol Biol Cell (2003) 1.20
Membrane organization and dynamics in cell polarity. Cold Spring Harb Perspect Biol (2009) 1.15
A Ral GAP complex links PI 3-kinase/Akt signaling to RalA activation in insulin action. Mol Biol Cell (2010) 1.13
The exocyst complex in exocytosis and cell migration. Protoplasma (2011) 1.12
The role of syntaxins in the specificity of vesicle targeting in polarized epithelial cells. Mol Biol Cell (2005) 1.09
Exocyst function is regulated by effector phosphorylation. Nat Cell Biol (2011) 1.08
The exocyst component Sec5 is present on endocytic vesicles in the oocyte of Drosophila melanogaster. J Cell Biol (2005) 1.07
WNT5A induces release of exosomes containing pro-angiogenic and immunosuppressive factors from malignant melanoma cells. Mol Cancer (2014) 1.05
Role of septins and the exocyst complex in the function of hydrolytic enzymes responsible for fission yeast cell separation. Mol Biol Cell (2005) 1.05
Rho3p regulates cell separation by modulating exocyst function in Schizosaccharomyces pombe. Genetics (2003) 1.02
Sec5, a member of the exocyst complex, mediates Drosophila embryo cellularization. Development (2010) 1.01
ERK1/2 regulate exocytosis through direct phosphorylation of the exocyst component Exo70. Dev Cell (2012) 0.98
Regulation of cell polarity by interactions of Msb3 and Msb4 with Cdc42 and polarisome components. Mol Cell Biol (2005) 0.97
The class V myosin Myo2p is required for Fus2p transport and actin polarization during the yeast mating response. Mol Biol Cell (2009) 0.95
The microtubule-associated Rho activating factor GEF-H1 interacts with exocyst complex to regulate vesicle traffic. Dev Cell (2012) 0.94
The polybasic juxtamembrane region of Sso1p is required for SNARE function in vivo. Eukaryot Cell (2005) 0.93
Out, in and back again: PtdIns(4,5)P(2) regulates cadherin trafficking in epithelial morphogenesis. Biochem J (2009) 0.91
Cytokinesis defines a spatial landmark for hepatocyte polarization and apical lumen formation. J Cell Sci (2014) 0.91
The synaptobrevin homologue Snc2p recruits the exocyst to secretory vesicles by binding to Sec6p. J Cell Biol (2013) 0.88
Mso1p regulates membrane fusion through interactions with the putative N-peptide-binding area in Sec1p domain 1. Mol Biol Cell (2010) 0.85
Sec1p and Mso1p C-terminal tails cooperate with the SNAREs and Sec4p in polarized exocytosis. Mol Biol Cell (2010) 0.81
Exo70 is transcriptionally up-regulated by hepatic nuclear factor 4α and contributes to cell cycle control in hepatoma cells. Oncotarget (2016) 0.77
A novel ROP/RAC GTPase effector integrates plant cell form and pattern formation. Plant Signal Behav (2008) 0.77
The Par3 polarity protein is an exocyst receptor essential for mammary cell survival. Nat Commun (2017) 0.75
GEF-H1: orchestrating the interplay between cytoskeleton and vesicle trafficking. Small GTPases (2013) 0.75
The exocyst is required for photoreceptor ciliogenesis and retinal development. J Biol Chem (2017) 0.75
A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science (2002) 42.78
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature (2006) 11.86
Rabs and their effectors: achieving specificity in membrane traffic. Proc Natl Acad Sci U S A (2006) 6.83
The cells and logic for mammalian sour taste detection. Nature (2006) 4.65
Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3beta and its upstream regulators. Cell (2005) 3.42
Randomized phase III trial of induction chemotherapy with docetaxel, cisplatin, and fluorouracil followed by surgery versus up-front surgery in locally advanced resectable oral squamous cell carcinoma. J Clin Oncol (2012) 3.08
Ypt32 recruits the Sec4p guanine nucleotide exchange factor, Sec2p, to secretory vesicles; evidence for a Rab cascade in yeast. J Cell Biol (2002) 3.08
The exocyst complex in polarized exocytosis. Curr Opin Cell Biol (2009) 3.04
Coordination of Rab8 and Rab11 in primary ciliogenesis. Proc Natl Acad Sci U S A (2010) 2.88
HIV prevalence in China: integration of surveillance data and a systematic review. Lancet Infect Dis (2013) 2.82
A chronic inflammatory response dominates the skeletal muscle molecular signature in dystrophin-deficient mdx mice. Hum Mol Genet (2002) 2.80
Vesicles carry most exocyst subunits to exocytic sites marked by the remaining two subunits, Sec3p and Exo70p. J Cell Biol (2004) 2.78
The exocyst defrocked, a framework of rods revealed. Nat Struct Mol Biol (2006) 2.52
An ESRP-regulated splicing programme is abrogated during the epithelial-mesenchymal transition. EMBO J (2010) 2.42
Antiretroviral therapy to prevent HIV transmission in serodiscordant couples in China (2003-11): a national observational cohort study. Lancet (2012) 2.41
The exocyst complex in polarized exocytosis. Int Rev Cytol (2004) 2.40
Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer. Genome Res (2012) 2.27
Detection of sequence-specific tyrosine nitration of manganese SOD and SERCA in cardiovascular disease and aging. Am J Physiol Heart Circ Physiol (2006) 2.19
Downregulation of XIAP and induction of apoptosis by the synthetic cyclin-dependent kinase inhibitor GW8510 in non-small cell lung cancer cells. Cancer Biol Ther (2006) 2.13
GTPase networks in membrane traffic. Annu Rev Biochem (2012) 2.10
Exo70 interacts with phospholipids and mediates the targeting of the exocyst to the plasma membrane. EMBO J (2007) 2.03
Membrane association and functional regulation of Sec3 by phospholipids and Cdc42. J Cell Biol (2008) 1.99
Estimating the number of people living with HIV/AIDS in China: 2003-09. Int J Epidemiol (2010) 1.96
Complementary roles for biomarkers of biomechanical strain ST2 and N-terminal prohormone B-type natriuretic peptide in patients with ST-elevation myocardial infarction. Circulation (2008) 1.95
Myo4p and She3p are required for cortical ER inheritance in Saccharomyces cerevisiae. J Cell Biol (2003) 1.92
A multicenter phase II study of ganetespib monotherapy in patients with genotypically defined advanced non-small cell lung cancer. Clin Cancer Res (2013) 1.90
Dynamics and inheritance of the endoplasmic reticulum. J Cell Sci (2004) 1.86
High level of AKT activity is associated with resistance to MEK inhibitor AZD6244 (ARRY-142886). Cancer Biol Ther (2009) 1.86
Rtn1p is involved in structuring the cortical endoplasmic reticulum. Mol Biol Cell (2006) 1.85
Optical virtual imaging at 50 nm lateral resolution with a white-light nanoscope. Nat Commun (2011) 1.85
Circulating stem cell-like epithelial cell adhesion molecule-positive tumor cells indicate poor prognosis of hepatocellular carcinoma after curative resection. Hepatology (2013) 1.84
A comparison of chemoembolization combination with and without radiotherapy for unresectable hepatocellular carcinoma. Cancer J (2004) 1.84
The structures of exocyst subunit Exo70p and the Exo84p C-terminal domains reveal a common motif. Nat Struct Mol Biol (2005) 1.79
Phosphatidylinositol 4,5-bisphosphate mediates the targeting of the exocyst to the plasma membrane for exocytosis in mammalian cells. Mol Biol Cell (2007) 1.77
Exo70 interacts with the Arp2/3 complex and regulates cell migration. Nat Cell Biol (2006) 1.70
The exocyst protein Sec10 is necessary for primary ciliogenesis and cystogenesis in vitro. Mol Biol Cell (2009) 1.68
Consideration of the role of radiotherapy for unresectable intrahepatic cholangiocarcinoma: a retrospective analysis of 75 patients. Cancer J (2006) 1.65
Differential expression of the RANKL/RANK/OPG system is associated with bone metastasis in human non-small cell lung cancer. PLoS One (2013) 1.64
Supraspinal glial-neuronal interactions contribute to descending pain facilitation. J Neurosci (2008) 1.61
Selective deletion of Pten in pancreatic beta cells leads to increased islet mass and resistance to STZ-induced diabetes. Mol Cell Biol (2006) 1.61
Enhancing TRAIL-induced apoptosis by Bcl-X(L) siRNA. Cancer Biol Ther (2005) 1.61
Sec3p is needed for the spatial regulation of secretion and for the inheritance of the cortical endoplasmic reticulum. Mol Biol Cell (2003) 1.59
Th17 immunity in patients with allergic asthma. Int Arch Allergy Immunol (2009) 1.58
Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. Am J Hum Genet (2013) 1.55
Identification of miRs-143 and -145 that is associated with bone metastasis of prostate cancer and involved in the regulation of EMT. PLoS One (2011) 1.55
The yeast lgl family member Sro7p is an effector of the secretory Rab GTPase Sec4p. J Cell Biol (2006) 1.54
Phosphatidylinositol 4-phosphate controls both membrane recruitment and a regulatory switch of the Rab GEF Sec2p. Dev Cell (2010) 1.52
Open and endovascular repair of primary mycotic aortic aneurysms: a 10-year single-center experience. J Endovasc Ther (2013) 1.51
Pag1p, a novel protein associated with protein kinase Cbk1p, is required for cell morphogenesis and proliferation in Saccharomyces cerevisiae. Mol Biol Cell (2002) 1.51
Prognostic significance of cyclooxygenase-2 in osteosarcoma: a meta-analysis. Tumour Biol (2013) 1.49
A catalytic coiled coil: structural insights into the activation of the Rab GTPase Sec4p by Sec2p. Mol Cell (2007) 1.48
Brominated flame retardants, polychlorinated biphenyls, and organochlorine pesticides in captive giant panda (ailuropoda melanoleuca) and red panda (Ailurus fulgens) from China. Environ Sci Technol (2008) 1.48
Lethal giant larvae proteins interact with the exocyst complex and are involved in polarized exocytosis. J Cell Biol (2005) 1.47
The exocyst localizes to the primary cilium in MDCK cells. Biochem Biophys Res Commun (2004) 1.47
miR-1303 targets claudin-18 gene to modulate proliferation and invasion of gastric cancer cells. Dig Dis Sci (2014) 1.46
Functional specialization within a vesicle tethering complex: bypass of a subset of exocyst deletion mutants by Sec1p or Sec4p. J Cell Biol (2004) 1.44
Mitotic phosphorylation of Exo84 disrupts exocyst assembly and arrests cell growth. J Cell Biol (2013) 1.43
Cyclical regulation of the exocyst and cell polarity determinants for polarized cell growth. Mol Biol Cell (2005) 1.42
SCM-198 attenuates early atherosclerotic lesions in hypercholesterolemic rabbits via modulation of the inflammatory and oxidative stress pathways. Atherosclerosis (2012) 1.41
The exocyst meets the translocon: a regulatory circuit for secretion and protein synthesis? Trends Cell Biol (2004) 1.40
Postoperative thoracic empyema might improve the survival of patients with esophageal cancer. Med Hypotheses (2007) 1.40
Helicobacter pylori infection may improve the survival of patients with carcinomas. Med Hypotheses (2007) 1.40
Up-regulation of tumor suppressor genes might promote the malignant phenotype of cancer cells. Med Hypotheses (2007) 1.39
Molecular depletion of descending serotonin unmasks its novel facilitatory role in the development of persistent pain. J Neurosci (2010) 1.37
The rab exchange factor Sec2p reversibly associates with the exocyst. Mol Biol Cell (2006) 1.35
The mammalian exocyst, a complex required for exocytosis, inhibits tubulin polymerization. J Biol Chem (2004) 1.35
HIV prevalence and influencing factors analysis of sentinel surveillance among men who have sex with men in China, 2003 - 2011. Chin Med J (Engl) (2012) 1.33
Distribution and contamination assessment of heavy metals in sediment of the Second Songhua River, China. Environ Monit Assess (2007) 1.32
ER network formation requires a balance of the dynamin-like GTPase Sey1p and the Lunapark family member Lnp1p. Nat Cell Biol (2012) 1.32
Mouse embryonic head as a site for hematopoietic stem cell development. Cell Stem Cell (2012) 1.31
Exo70p mediates the secretion of specific exocytic vesicles at early stages of the cell cycle for polarized cell growth. J Cell Biol (2007) 1.31
Cdc42 and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice. J Clin Invest (2012) 1.31
[HIV prevalence among populations at risk, using sentinel surveillance data from 1995 to 2009 in China]. Zhonghua Liu Xing Bing Xue Za Zhi (2011) 1.30
Bik/NBK accumulation correlates with apoptosis-induction by bortezomib (PS-341, Velcade) and other proteasome inhibitors. Oncogene (2005) 1.29
Loci influencing blood pressure identified using a cardiovascular gene-centric array. Hum Mol Genet (2013) 1.27
The role of the exocyst in matrix metalloproteinase secretion and actin dynamics during tumor cell invadopodia formation. Mol Biol Cell (2009) 1.27
The critical role of Exo84p in the organization and polarized localization of the exocyst complex. J Biol Chem (2005) 1.27
Radiation therapy for adrenal gland metastases from hepatocellular carcinoma. Jpn J Clin Oncol (2005) 1.25
Modulation of behavioral phase changes of the migratory locust by the catecholamine metabolic pathway. Proc Natl Acad Sci U S A (2011) 1.24
The Rho family of small GTPases is involved in epithelial cystogenesis and tubulogenesis. Kidney Int (2003) 1.24
Isolation, growth and differentiation of hair cell progenitors from the newborn rat cochlear greater epithelial ridge. J Neurosci Methods (2007) 1.23
[Data analysis of national HIV comprehensive surveillance sites among female sex workers from 2004 to 2008]. Zhonghua Yu Fang Yi Xue Za Zhi (2009) 1.22
The cluster of miR-143 and miR-145 affects the risk for esophageal squamous cell carcinoma through co-regulating fascin homolog 1. PLoS One (2012) 1.22
A spring-loaded state of NusG in its functional cycle is suggested by X-ray crystallography and supported by site-directed mutants. Biochemistry (2003) 1.22
Economical Pt-free catalysts for counter electrodes of dye-sensitized solar cells. J Am Chem Soc (2012) 1.21
Mutation that dramatically alters rat titin isoform expression and cardiomyocyte passive tension. J Mol Cell Cardiol (2008) 1.20
Persistent over-expression of specific CC class chemokines correlates with macrophage and T-cell recruitment in mdx skeletal muscle. Neuromuscul Disord (2003) 1.19
Polymorphisms in the MMP1 and MMP3 promoter and non-small cell lung carcinoma in North China. Carcinogenesis (2004) 1.18
Aberrant expression of proteins involved in signal transduction and DNA repair pathways in lung cancer and their association with clinical parameters. PLoS One (2012) 1.17
MicroRNA-9 up-regulates E-cadherin through inhibition of NF-κB1-Snail1 pathway in melanoma. J Pathol (2011) 1.17
Differential expression profiles of microRNAs as potential biomarkers for the early diagnosis of esophageal squamous cell carcinoma. Oncol Rep (2012) 1.16
ER structure and function. Curr Opin Cell Biol (2013) 1.15
Membrane organization and dynamics in cell polarity. Cold Spring Harb Perspect Biol (2009) 1.15
Biomimetic smart nanopores and nanochannels. Chem Soc Rev (2011) 1.15
A Rab8 guanine nucleotide exchange factor-effector interaction network regulates primary ciliogenesis. J Biol Chem (2012) 1.14
Rabs and the exocyst in ciliogenesis, tubulogenesis and beyond. Trends Cell Biol (2011) 1.14
The exocyst complex in exocytosis and cell migration. Protoplasma (2011) 1.12
The functional polymorphism in the matrix metalloproteinase-7 promoter increases susceptibility to esophageal squamous cell carcinoma, gastric cardiac adenocarcinoma and non-small cell lung carcinoma. Carcinogenesis (2005) 1.12
JAK2/STAT3 pathway is involved in the early stage of adipogenesis through regulating C/EBPβ transcription. J Cell Biochem (2011) 1.12
miR-143 and miR-145 inhibit stem cell characteristics of PC-3 prostate cancer cells. Oncol Rep (2012) 1.12