Published in Genes Cells on July 01, 2002
The Cryptococcus neoformans MAP kinase Mpk1 regulates cell integrity in response to antifungal drugs and loss of calcineurin function. Mol Microbiol (2003) 1.81
Functional characterization of the Candida albicans CRZ1 gene encoding a calcineurin-regulated transcription factor. Curr Genet (2005) 1.18
Loss of Apm1, the micro1 subunit of the clathrin-associated adaptor-protein-1 complex, causes distinct phenotypes and synthetic lethality with calcineurin deletion in fission yeast. Mol Biol Cell (2004) 1.18
Localization and activity of the calcineurin catalytic and regulatory subunit complex at the septum is essential for hyphal elongation and proper septation in Aspergillus fumigatus. Mol Microbiol (2011) 1.14
Phospholipid-binding protein Cts1 controls septation and functions coordinately with calcineurin in Cryptococcus neoformans. Eukaryot Cell (2003) 1.04
Stress-activated protein kinase-mediated down-regulation of the cell integrity pathway mitogen-activated protein kinase Pmk1p by protein phosphatases. Mol Biol Cell (2007) 0.98
Atf1 is a target of the mitogen-activated protein kinase Pmk1 and regulates cell integrity in fission yeast. Mol Biol Cell (2007) 0.94
Calcineurin as a Multifunctional Regulator: Unraveling Novel Functions in Fungal Stress Responses, Hyphal Growth, Drug Resistance, and Pathogenesis. Fungal Biol Rev (2014) 0.90
The cell surface protein gene ecm33+ is a target of the two transcription factors Atf1 and Mbx1 and negatively regulates Pmk1 MAPK cell integrity signaling in fission yeast. Mol Biol Cell (2009) 0.89
Glucose activates TORC2-Gad8 protein via positive regulation of the cAMP/cAMP-dependent protein kinase A (PKA) pathway and negative regulation of the Pmk1 protein-mitogen-activated protein kinase pathway. J Biol Chem (2014) 0.86
Components of the calcium-calcineurin signaling pathway in fungal cells and their potential as antifungal targets. Eukaryot Cell (2015) 0.85
Schizosaccharomyces pombe Pmr1p is essential for cell wall integrity and is required for polarized cell growth and cytokinesis. Eukaryot Cell (2004) 0.84
Valproic acid affects membrane trafficking and cell-wall integrity in fission yeast. Genetics (2007) 0.84
Negative feedback regulation of calcineurin-dependent Prz1 transcription factor by the CaMKK-CaMK1 axis in fission yeast. Nucleic Acids Res (2014) 0.82
Genome-wide screening for genes associated with FK506 sensitivity in fission yeast. PLoS One (2011) 0.82
Fingolimod (FTY720) stimulates Ca(2+)/calcineurin signaling in fission yeast. PLoS One (2013) 0.81
P(5A)-type ATPase Cta4p is essential for Ca2+ transport in the endoplasmic reticulum of Schizosaccharomyces pombe. PLoS One (2011) 0.81
Negative functional interaction between cell integrity MAPK pathway and Rho1 GTPase in fission yeast. Genetics (2013) 0.80
Calmodulin binding to Dfi1p promotes invasiveness of Candida albicans. PLoS One (2013) 0.79
Structure of cyclophilin from Leishmania donovani at 1.97 A resolution. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.78
Calcineurin-mediated regulation of hyphal growth, septation, and virulence in Aspergillus fumigatus. Mycopathologia (2014) 0.77
Novel motif in calcineurin catalytic subunit is required for septal localization of calcineurin in Aspergillus fumigatus. FEBS Lett (2016) 0.76
Calcineurin Orchestrates Hyphal Growth, Septation, Drug Resistance and Pathogenesis of Aspergillus fumigatus: Where Do We Go from Here? Pathogens (2015) 0.76
Endosomal Trafficking Defects Can Induce Calcium-Dependent Azole Tolerance in Candida albicans. Antimicrob Agents Chemother (2016) 0.75
Zinc finger protein Prz1 regulates Ca2+ but not Cl- homeostasis in fission yeast. Identification of distinct branches of calcineurin signaling pathway in fission yeast. J Biol Chem (2003) 1.20
Loss of Apm1, the micro1 subunit of the clathrin-associated adaptor-protein-1 complex, causes distinct phenotypes and synthetic lethality with calcineurin deletion in fission yeast. Mol Biol Cell (2004) 1.18
Role of the Rab GTP-binding protein Ypt3 in the fission yeast exocytic pathway and its connection to calcineurin function. Mol Biol Cell (2002) 1.17
Real-time monitoring of calcineurin activity in living cells: evidence for two distinct Ca2+-dependent pathways in fission yeast. Mol Biol Cell (2006) 1.14
Rho2 is a target of the farnesyltransferase Cpp1 and acts upstream of Pmk1 mitogen-activated protein kinase signaling in fission yeast. Mol Biol Cell (2006) 1.12
The role of the regulatory subunit of fission yeast calcineurin for in vivo activity and its relevance to FK506 sensitivity. J Biol Chem (2005) 1.05
Lub1 participates in ubiquitin homeostasis and stress response via maintenance of cellular ubiquitin contents in fission yeast. Mol Cell Biol (2004) 1.04
Feedback regulation of MAPK signalling by an RNA-binding protein. Nature (2003) 1.01
Atf1 is a target of the mitogen-activated protein kinase Pmk1 and regulates cell integrity in fission yeast. Mol Biol Cell (2007) 0.94
Deletion mutants of AP-1 adaptin subunits display distinct phenotypes in fission yeast. Genes Cells (2009) 0.94
Estrogen levels influence beta-3-adrenoceptor-mediated relaxation of the female rat detrusor muscle. Urology (2002) 0.93
Genetic and functional interaction between Ryh1 and Ypt3: two Rab GTPases that function in S. pombe secretory pathway. Genes Cells (2006) 0.93
Phosphatidylinositol-4-phosphate 5-kinase regulates fission yeast cell integrity through a phospholipase C-mediated protein kinase C-independent pathway. J Biol Chem (2005) 0.92
Genome-wide screen reveals novel mechanisms for regulating cobalt uptake and detoxification in fission yeast. Mol Genet Genomics (2012) 0.92
Calcineurin is implicated in the regulation of the septation initiation network in fission yeast. Genes Cells (2002) 0.92
Pmr1, a P-type ATPase, and Pdt1, an Nramp homologue, cooperatively regulate cell morphogenesis in fission yeast: the importance of Mn2+ homeostasis. Genes Cells (2004) 0.91
Wobble inosine tRNA modification is essential to cell cycle progression in G(1)/S and G(2)/M transitions in fission yeast. J Biol Chem (2007) 0.91
Six new amino acid-auxotrophic markers for targeted gene integration and disruption in fission yeast. Curr Genet (2007) 0.89
Transient receptor potential (TRP) and Cch1-Yam8 channels play key roles in the regulation of cytoplasmic Ca2+ in fission yeast. PLoS One (2011) 0.89
MAP kinase kinase kinase (MAPKKK)-dependent and -independent activation of Sty1 stress MAPK in fission yeast. J Biol Chem (2010) 0.86
Genetic evidence for phospholipid-mediated regulation of the Rab GDP-dissociation inhibitor in fission yeast. Genetics (2006) 0.86
Cation diffusion facilitator Cis4 is implicated in Golgi membrane trafficking via regulating zinc homeostasis in fission yeast. Mol Biol Cell (2008) 0.84
Genetic interaction between calcineurin and type 2 myosin and their involvement in the regulation of cytokinesis and chloride ion homeostasis in fission yeast. Genetics (2002) 0.84
Valproic acid affects membrane trafficking and cell-wall integrity in fission yeast. Genetics (2007) 0.84
A genomewide screen in Schizosaccharomyces pombe for genes affecting the sensitivity of antifungal drugs that target ergosterol biosynthesis. Antimicrob Agents Chemother (2012) 0.82
Isolation of a fission yeast mutant that is sensitive to valproic acid and defective in the gene encoding Ric1, a putative component of Ypt/Rab-specific GEF for Ryh1 GTPase. Mol Genet Genomics (2010) 0.82
Genome-wide screening for genes associated with FK506 sensitivity in fission yeast. PLoS One (2011) 0.82
Association of calcineurin A gamma subunit (PPP3CC) and early growth response 3 (EGR3) gene polymorphisms with susceptibility to schizophrenia in a Japanese population. Psychiatry Res (2011) 0.82
Pleiotropic phenotypes caused by an opal nonsense mutation in an essential gene encoding HMG-CoA reductase in fission yeast. Genes Cells (2009) 0.81
A measurable activation of the bZIP transcription factor Atf1 in a fission yeast strain devoid of stress-activated and cell integrity mitogen-activated protein kinase (MAPK) activities. J Biol Chem (2012) 0.81
A genetic and pharmacological analysis of isoprenoid pathway by LC-MS/MS in fission yeast. PLoS One (2012) 0.80
Upregulation of mRNA in MAPK signaling: transcriptional activation or mRNA stabilization? Cell Cycle (2004) 0.80
Lack of association between tyrosine kinase 2 (TYK2) gene polymorphisms and susceptibility to SLE in a Japanese population. Mod Rheumatol (2009) 0.79
A genome-wide screening of potential target genes to enhance the antifungal activity of micafungin in Schizosaccharomyces pombe. PLoS One (2013) 0.79
Genetic screening for regulators of Prz1, a transcriptional factor acting downstream of calcineurin in fission yeast. J Biol Chem (2012) 0.79
Change in tongue morphology in response to expiratory resistance loading investigated by magnetic resonance imaging. J Phys Ther Sci (2013) 0.78
Studies on the roles of clathrin-mediated membrane trafficking and zinc transporter Cis4 in the transport of GPI-anchored proteins in fission yeast. PLoS One (2012) 0.77
Comparison of toxicity and toxicokinetics/pharmacokinetics of an alpha 1L-adrenoceptor agonist in rats and rhesus monkeys. J Pharmacol Sci (2005) 0.76
Fission yeast epsin, Ent1p is required for endocytosis and involved in actin organization. Kobe J Med Sci (2004) 0.76
Preclinical safety pharmacology study of a novel protein-based cancer vaccine CHP-NY-ESO-1. Kobe J Med Sci (2008) 0.75
Studies on fungal Pumilio gene family through mining multiple genome-scale data sets. Kobe J Med Sci (2007) 0.75
[Cell regulation through calcineurin signalling]. Seikagaku (2005) 0.75
Expression of mPOU protein in the human pituitary adenomas. Kobe J Med Sci (2003) 0.75
Isolation of a fission yeast mutant cell affected in MAP kinase signaling and sterol biosynthesis. Kobe J Med Sci (2009) 0.75
Qualitative and relative quantitative analysis of urinary components with linear ion trap and FT ICR mass spectrometer to search for biomarkers. Kobe J Med Sci (2009) 0.75
[Yeast as a model system for drug discovery]. Nihon Yakurigaku Zasshi (2005) 0.75