Published in Am J Pathol on July 01, 2002
Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases. J Clin Invest (2003) 6.44
A 20-year history of childhood HIV-associated nephropathy. Pediatr Nephrol (2004) 1.25
Circulating plasma factors induce tubular and glomerular alterations in septic burns patients. Crit Care (2008) 1.22
Polymyxin-B hemoperfusion inactivates circulating proapoptotic factors. Intensive Care Med (2008) 1.11
Controversies in the pathogenesis of HIV-associated renal diseases. Nat Rev Nephrol (2009) 1.08
Persistent replication of severe acute respiratory syndrome coronavirus in human tubular kidney cells selects for adaptive mutations in the membrane protein. J Virol (2008) 1.00
Podocyte Number in Children and Adults: Associations with Glomerular Size and Numbers of Other Glomerular Resident Cells. J Am Soc Nephrol (2015) 0.89
Taking a hard look at the pathogenesis of childhood HIV-associated nephropathy. Pediatr Nephrol (2009) 0.89
Proliferative activity of extracellular HIV-1 Tat protein in human epithelial cells: expression profile of pathogenetically relevant genes. BMC Microbiol (2005) 0.88
Stem cells: potential and challenges for kidney repair. Am J Physiol Renal Physiol (2013) 0.88
HIV-1 and kidney cells: better understanding of viral interaction. Nephron Exp Nephrol (2010) 0.87
Advances in our understanding of the pathogenesis of HIV-1 associated nephropathy in children. Future Virol (2011) 0.85
Genetic susceptibility to HIV-associated nephropathy. J Clin Invest (2009) 0.85
Inflammatory papillomatous hyperplasia and epidermal necrosis in a transgenic rat for HIV-1. J Dermatol Sci (2008) 0.81
Inhibition of Notch pathway attenuates the progression of human immunodeficiency virus-associated nephropathy. Am J Physiol Renal Physiol (2013) 0.80
The basic domain of HIV-tat transactivating protein is essential for its targeting to lipid rafts and regulating fibroblast growth factor-2 signaling in podocytes isolated from children with HIV-1-associated nephropathy. J Am Soc Nephrol (2014) 0.80
New insights into glomerular parietal epithelial cell activation and its signaling pathways in glomerular diseases. Biomed Res Int (2015) 0.77
Src family kinases in chronic kidney disease. Am J Physiol Renal Physiol (2017) 0.75
Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120. Nature (1995) 4.95
An improved colorimetric assay for cell proliferation and viability utilizing the tetrazolium salt XTT. J Immunol Methods (1991) 4.55
Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytes. J Cell Biol (1997) 4.43
A heparin-binding angiogenic protein--basic fibroblast growth factor--is stored within basement membrane. Am J Pathol (1988) 3.72
Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation. J Virol (1993) 3.68
Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein. Science (1995) 3.46
The dysregulated podocyte phenotype: a novel concept in the pathogenesis of collapsing idiopathic focal segmental glomerulosclerosis and HIV-associated nephropathy. J Am Soc Nephrol (1999) 3.46
The biochemistry of AIDS. Annu Rev Biochem (1991) 3.06
Internalization of HIV-1 tat requires cell surface heparan sulfate proteoglycans. J Biol Chem (2000) 2.98
Multifaceted activities of the HIV-1 transactivator of transcription, Tat. J Biol Chem (1999) 2.81
Renal epithelium is a previously unrecognized site of HIV-1 infection. J Am Soc Nephrol (2000) 2.57
Glomerular cell culture. Lab Invest (1985) 2.16
Structure and function of podocytes: an update. Anat Embryol (Berl) (1995) 2.02
The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi sarcoma and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequence. Proc Natl Acad Sci U S A (1993) 1.93
Nephropathy and establishment of a renal reservoir of HIV type 1 during primary infection. N Engl J Med (2001) 1.83
Identification of a human immunodeficiency virus type 1 Tat epitope that is neuroexcitatory and neurotoxic. J Virol (1996) 1.78
Nephropathy in human immunodeficiency virus-1 transgenic mice is due to renal transgene expression. J Clin Invest (1997) 1.77
HIV-1 induces renal epithelial dedifferentiation in a transgenic model of HIV-associated nephropathy. Kidney Int (2000) 1.75
The angiogenesis induced by HIV-1 tat protein is mediated by the Flk-1/KDR receptor on vascular endothelial cells. Nat Med (1996) 1.72
Vascular endothelial growth factor receptor-1 modulates vascular endothelial growth factor-mediated angiogenesis via nitric oxide. Am J Pathol (2001) 1.69
Podocyte cell cycle regulation and proliferation in collapsing glomerulopathies. Kidney Int (2000) 1.58
Nephrin redistribution on podocytes is a potential mechanism for proteinuria in patients with primary acquired nephrotic syndrome. Am J Pathol (2001) 1.57
Differential expression of cyclin-dependent kinase inhibitors in human glomerular disease: role in podocyte proliferation and maturation. Kidney Int (2000) 1.49
HIV-1 kills renal tubular epithelial cells in vitro by triggering an apoptotic pathway involving caspase activation and Fas upregulation. J Clin Invest (1998) 1.49
Glomerular heparan sulfate alterations: mechanisms and relevance for proteinuria. Kidney Int (2000) 1.37
Renal pathology of human immunodeficiency virus infection. Semin Nephrol (1998) 1.28
Block of AIDS-Kaposi's sarcoma (KS) cell growth, angiogenesis, and lesion formation in nude mice by antisense oligonucleotide targeting basic fibroblast growth factor. A novel strategy for the therapy of KS. J Clin Invest (1994) 1.21
Cell cycle regulation and differentiation in the human podocyte lineage. Am J Pathol (1998) 1.17
HIV-associated nephropathy. Kidney Int (1999) 1.16
Basic fibroblast growth factor expression is increased in human renal fibrogenesis and may mediate autocrine fibroblast proliferation. Kidney Int (2000) 1.15
Multiple interactions of HIV-I Tat protein with size-defined heparin oligosaccharides. J Biol Chem (1999) 1.13
Inflammatory cytokines synergize with the HIV-1 Tat protein to promote angiogenesis and Kaposi's sarcoma via induction of basic fibroblast growth factor and the alpha v beta 3 integrin. J Immunol (1999) 1.10
The role of vasoactive compounds, growth factors and cytokines in the progression of renal disease. Kidney Int Suppl (2000) 1.10
bFGF and its low affinity receptors in the pathogenesis of HIV-associated nephropathy in transgenic mice. Kidney Int (1994) 1.09
Pronounced acute immunosuppression in vivo mediated by HIV Tat challenge. Proc Natl Acad Sci U S A (1999) 1.08
HIV-1 transactivator protein Tat induces proliferation and TGF beta expression in human articular chondrocytes. J Cell Biol (1994) 1.05
Stable cell line of T-SV40 immortalized human glomerular visceral epithelial cells. Kidney Int (1991) 1.04
Basic fibroblast growth factor in HIV-associated hemolytic uremic syndrome. Pediatr Nephrol (1999) 1.04
The basic domain in HIV-1 Tat protein as a target for polysulfonated heparin-mimicking extracellular Tat antagonists. J Biol Chem (1998) 1.01
Distinct pathogenic effects of group B coxsackieviruses on human glomerular and tubular kidney cells. J Virol (1997) 1.01
The human immunodeficiency virus (HIV) epidemic and HIV-associated nephropathy. Semin Nephrol (1998) 1.00
Increased levels of transforming growth factor-beta in HIV-associated nephropathy. Kidney Int (1999) 0.99
HIV infects glomerular endothelial and mesangial but not epithelial cells in vitro. Kidney Int (1992) 0.97
Pathogenesis of human immunodeficiency virus (HIV)-associated nephropathy. Semin Nephrol (1998) 0.96
Heparan sulfate-like proteoglycans mediate adhesion of human malignant melanoma A375 cells to P-selectin under flow. J Immunol (2000) 0.91
Tumor necrosis factor alters cytoskeletal organization and barrier function of endothelial cells. Int Arch Allergy Appl Immunol (1991) 0.91
Basic fibroblast growth factor promotes proliferation of rat glomerular visceral epithelial cells in vitro. Am J Pathol (1992) 0.88
Motility induced by human immunodeficiency virus-1 Tat on Kaposi's sarcoma cells requires platelet-activating factor synthesis. Am J Pathol (1999) 0.87
HIV-persistent infection and cytokine induction in mesangial cells: a potential mechanism for HIV-associated glomerulosclerosis. AIDS (2000) 0.87
HIV type 1 Tat protein is a survival factor for Kaposi's sarcoma and endothelial cells. AIDS Res Hum Retroviruses (2001) 0.87
TGF-beta1 stimulates the release of pre-formed bFGF from renal proximal tubular cells. Kidney Int (1999) 0.83
Cytokines and podocyte injury: the mechanism of fibroblast growth factor 2-induced podocyte injury. Nephrol Dial Transplant (1999) 0.82
The synthesis of platelet-activating factor modulates chemotaxis of monocytes induced by HIV-1 Tat. Eur J Immunol (1999) 0.82
Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. J Am Soc Nephrol (2009) 5.01
Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mRNA. Blood (2007) 4.73
Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche. Cancer Res (2011) 3.50
Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury. Nephrol Dial Transplant (2011) 3.49
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. PLoS Biol (2012) 3.18
Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs. PLoS One (2010) 3.14
Isolation of renal progenitor cells from adult human kidney. Am J Pathol (2005) 3.12
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. Arch Toxicol (2013) 3.00
Microvesicles derived from endothelial progenitor cells protect the kidney from ischemia-reperfusion injury by microRNA-dependent reprogramming of resident renal cells. Kidney Int (2012) 2.47
Isolation and characterization of a stem cell population from adult human liver. Stem Cells (2006) 2.25
Human liver stem cells improve liver injury in a model of fulminant liver failure. Hepatology (2013) 2.24
Microvesicles derived from mesenchymal stem cells enhance survival in a lethal model of acute kidney injury. PLoS One (2012) 2.23
Nephrin expression is reduced in human diabetic nephropathy: evidence for a distinct role for glycated albumin and angiotensin II. Diabetes (2003) 2.17
Mesenchymal stem cells contribute to the renal repair of acute tubular epithelial injury. Int J Mol Med (2004) 2.16
Exosome/microvesicle-mediated epigenetic reprogramming of cells. Am J Cancer Res (2010) 1.96
Microvesicles derived from human bone marrow mesenchymal stem cells inhibit tumor growth. Stem Cells Dev (2012) 1.91
Therapeutic potential of mesenchymal stem cell-derived microvesicles. Nephrol Dial Transplant (2012) 1.88
Identification of a tumor-initiating stem cell population in human renal carcinomas. FASEB J (2008) 1.88
Altered angiogenesis and survival in human tumor-derived endothelial cells. FASEB J (2003) 1.61
CEP-18770: A novel, orally active proteasome inhibitor with a tumor-selective pharmacologic profile competitive with bortezomib. Blood (2007) 1.54
Brains and peripheral blood mononuclear cells of multiple sclerosis (MS) patients hyperexpress MS-associated retrovirus/HERV-W endogenous retrovirus, but not Human herpesvirus 6. J Gen Virol (2007) 1.50
Human breast milk and xenoestrogen exposure: a possible impact on human health. J Perinatol (2005) 1.45
Preeclamptic sera induce nephrin shedding from podocytes through endothelin-1 release by endothelial glomerular cells. Am J Physiol Renal Physiol (2008) 1.41
Growth factor delivery from hydrogel particle aggregates to promote tubular regeneration after acute kidney injury. J Control Release (2013) 1.40
CD133+ renal progenitor cells contribute to tumor angiogenesis. Am J Pathol (2006) 1.36
Extracellular vesicles as an emerging mechanism of cell-to-cell communication. Endocrine (2012) 1.32
Endothelial cell differentiation of human breast tumour stem/progenitor cells. J Cell Mol Med (2009) 1.30
Effect of the monocyte chemoattractant protein-1/CC chemokine receptor 2 system on nephrin expression in streptozotocin-treated mice and human cultured podocytes. Diabetes (2009) 1.25
HIV-1-Tat protein activates phosphatidylinositol 3-kinase/ AKT-dependent survival pathways in Kaposi's sarcoma cells. J Biol Chem (2002) 1.24
Human liver stem cell-derived microvesicles inhibit hepatoma growth in SCID mice by delivering antitumor microRNAs. Stem Cells (2012) 1.23
Hypoxia modulates the undifferentiated phenotype of human renal inner medullary CD133+ progenitors through Oct4/miR-145 balance. Am J Physiol Renal Physiol (2011) 1.23
Stem cells derived from human amniotic fluid contribute to acute kidney injury recovery. Am J Pathol (2010) 1.22
Circulating plasma factors induce tubular and glomerular alterations in septic burns patients. Crit Care (2008) 1.22
Isolation and characterization of resident mesenchymal stem cells in human glomeruli. Stem Cells Dev (2009) 1.20
Contribution of stem cells to kidney repair. Curr Stem Cell Res Ther (2009) 1.20
Sorafenib blocks tumour growth, angiogenesis and metastatic potential in preclinical models of osteosarcoma through a mechanism potentially involving the inhibition of ERK1/2, MCL-1 and ezrin pathways. Mol Cancer (2009) 1.20
Macrophage stimulating protein may promote tubular regeneration after acute injury. J Am Soc Nephrol (2008) 1.19
The dynamic stem cell microenvironment is orchestrated by microvesicle-mediated transfer of genetic information. Histol Histopathol (2010) 1.19
Statins prevent oxidized LDL-induced injury of glomerular podocytes by activating the phosphatidylinositol 3-kinase/AKT-signaling pathway. J Am Soc Nephrol (2005) 1.16
The role of microvesicles in tissue repair. Organogenesis (2011) 1.15
Role of Pax2 in apoptosis resistance and proinvasive phenotype of Kaposi's sarcoma cells. J Biol Chem (2003) 1.15
Contribution of stem cells to kidney repair. Am J Nephrol (2008) 1.15
Improved route for the visualization of stem cells labeled with a Gd-/Eu-chelate as dual (MRI and fluorescence) agent. Magn Reson Med (2004) 1.15
Microvesicles derived from endothelial progenitor cells enhance neoangiogenesis of human pancreatic islets. Cell Transplant (2012) 1.14
Circulating endothelial progenitor cells and large artery structure and function in young subjects with uncomplicated type 1 diabetes. Cardiovasc Diabetol (2011) 1.13
Polymyxin-B hemoperfusion inactivates circulating proapoptotic factors. Intensive Care Med (2008) 1.11
Magnetic resonance imaging of gadolinium-labeled pancreatic islets for experimental transplantation. NMR Biomed (2007) 1.08
Sca-1 identifies the tumor-initiating cells in mammary tumors of BALB-neuT transgenic mice. Neoplasia (2008) 1.07
Tumor exploits alternative strategies to achieve vascularization. FASEB J (2011) 1.07
Magnetic resonance visualization of tumor angiogenesis by targeting neural cell adhesion molecules with the highly sensitive gadolinium-loaded apoferritin probe. Cancer Res (2006) 1.07
Calpain activation and secretion promote glomerular injury in experimental glomerulonephritis: evidence from calpastatin-transgenic mice. J Am Soc Nephrol (2006) 1.06
Novel reliable real-time PCR for differential detection of MSRVenv and syncytin-1 in RNA and DNA from patients with multiple sclerosis. J Virol Methods (2009) 1.06
Differentiation therapy: targeting human renal cancer stem cells with interleukin 15. J Natl Cancer Inst (2011) 1.05
CD40-dependent activation of phosphatidylinositol 3-kinase/Akt pathway mediates endothelial cell survival and in vitro angiogenesis. J Biol Chem (2003) 1.04
C-KIT, by interacting with the membrane-bound ligand, recruits endothelial progenitor cells to inflamed endothelium. Blood (2007) 1.02
The monocyte chemoattractant protein-1/cognate CC chemokine receptor 2 system affects cell motility in cultured human podocytes. Am J Pathol (2007) 1.01
Cellular phenotype and extracellular vesicles: basic and clinical considerations. Stem Cells Dev (2014) 1.00
Role of mesenchymal stem cell-derived microvesicles in tissue repair. Pediatr Nephrol (2013) 1.00
HIV-1 Tat reduces nephrin in human podocytes: a potential mechanism for enhanced glomerular permeability in HIV-associated nephropathy. AIDS (2007) 1.00
Catheter-related candidemia caused by Candida lipolytica in a patient receiving allogeneic bone marrow transplantation. J Clin Microbiol (2002) 1.00
Isolation and characterization of human breast tumor-derived endothelial cells. Oncol Rep (2006) 0.99
Vitamin D status and predictors of hypovitaminosis D in Italian children and adolescents: a cross-sectional study. Eur J Pediatr (2013) 0.98
Mechanisms of the priming effect of low doses of lipopoly-saccharides on leukocyte-dependent platelet aggregation in whole blood. Thromb Haemost (2003) 0.97
Aberrantly glycosylated IgA1 induces mesangial cells to produce platelet-activating factor that mediates nephrin loss in cultured podocytes. Kidney Int (2009) 0.97
Expression and activation by Epstein Barr virus of human endogenous retroviruses-W in blood cells and astrocytes: inference for multiple sclerosis. PLoS One (2012) 0.97
Post-apoptotic tumors are more palatable to dendritic cells and enhance their antigen cross-presentation activity. Vaccine (2008) 0.96
Concise review: stem/progenitor cells for renal tissue repair: current knowledge and perspectives. Stem Cells Transl Med (2013) 0.96
Cytotoxic activity of the histone deacetylase inhibitor panobinostat (LBH589) in anaplastic thyroid cancer in vitro and in vivo. Int J Cancer (2011) 0.95
Differentiation of podocyte and proximal tubule-like cells from a mouse kidney-derived stem cell line. Stem Cells Dev (2011) 0.95
Oxytocin induces proliferation and migration in immortalized human dermal microvascular endothelial cells and human breast tumor-derived endothelial cells. Mol Cancer Res (2006) 0.95
Insight on the pathogenesis of diabetic nephropathy from the study of podocyte and mesangial cell biology. Curr Diabetes Rev (2005) 0.94
Persistent infection of human microvascular endothelial cells by coxsackie B viruses induces increased expression of adhesion molecules. J Immunol (2003) 0.94
Inhibition of multiple-sclerosis-associated retrovirus as biomarker of interferon therapy. J Neurovirol (2008) 0.94
Histone deacetylase inhibition modulates E-cadherin expression and suppresses migration and invasion of anaplastic thyroid cancer cells. J Clin Endocrinol Metab (2012) 0.93
Stretch reduces nephrin expression via an angiotensin II-AT(1)-dependent mechanism in human podocytes: effect of rosiglitazone. Am J Physiol Renal Physiol (2009) 0.92
Rationale of mesenchymal stem cell therapy in kidney injury. Am J Kidney Dis (2012) 0.92
Platelet-activating factor inactivation by local expression of platelet-activating factor acetyl-hydrolase modifies tumor vascularization and growth. Clin Cancer Res (2003) 0.92
Epithelial-mesenchymal transition of ovarian tumor cells induces an angiogenic monocyte cell population. Exp Cell Res (2009) 0.92