Published in Am J Physiol Endocrinol Metab on August 01, 2002
Adverse events associated with testosterone administration. N Engl J Med (2010) 10.94
Risks and benefits of testosterone therapy in older men. Nat Rev Endocrinol (2013) 2.47
Drug insight: Testosterone and selective androgen receptor modulators as anabolic therapies for chronic illness and aging. Nat Clin Pract Endocrinol Metab (2006) 1.63
Free testosterone levels are associated with mobility limitation and physical performance in community-dwelling men: the Framingham Offspring Study. J Clin Endocrinol Metab (2010) 1.62
The effects of serum testosterone, estradiol, and sex hormone binding globulin levels on fracture risk in older men. J Clin Endocrinol Metab (2009) 1.52
Clinical meaningfulness of the changes in muscle performance and physical function associated with testosterone administration in older men with mobility limitation. J Gerontol A Biol Sci Med Sci (2011) 1.43
The association of testosterone levels with overall sleep quality, sleep architecture, and sleep-disordered breathing. J Clin Endocrinol Metab (2008) 1.29
Association between testosterone and estradiol and age-related decline in physical function in a diverse sample of men. J Am Geriatr Soc (2008) 1.24
Changes in muscle mass, muscle strength, and power but not physical function are related to testosterone dose in healthy older men. J Am Geriatr Soc (2008) 1.13
The role of androgens and estrogens on healthy aging and longevity. J Gerontol A Biol Sci Med Sci (2012) 1.13
Hormone replacement therapy and physical function in healthy older men. Time to talk hormones? Endocr Rev (2012) 1.01
Testosterone for the aging male; current evidence and recommended practice. Clin Interv Aging (2008) 0.98
Selective androgen receptor modulators as function promoting therapies. Curr Opin Clin Nutr Metab Care (2009) 0.98
The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men. J Gerontol A Biol Sci Med Sci (2012) 0.96
Muscle function, physical performance and body composition changes in men with prostate cancer undergoing androgen deprivation therapy. Asian J Androl (2012) 0.92
Sex steroid hormone levels and body composition in men. J Clin Endocrinol Metab (2013) 0.91
Metabolic effects of testosterone replacement therapy on hypogonadal men with type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials. Asian J Androl (2013) 0.85
Graded inhibition of pulsatile luteinizing hormone secretion by a selective gonadotropin-releasing hormone (GnRH)-receptor antagonist in healthy men: evidence that age attenuates hypothalamic GnRH outflow. J Clin Endocrinol Metab (2005) 0.84
Androgen effects on skeletal muscle: implications for the development and management of frailty. Asian J Androl (2014) 0.83
Interaction of APOE genotype and testosterone on episodic memory in middle-aged men. Neurobiol Aging (2013) 0.77
Combined administration of testosterone plus an ornithine decarboxylase inhibitor as a selective prostate-sparing anabolic therapy. Aging Cell (2013) 0.77
Aging and Sex Hormones in Males. Virulence (2016) 0.76
Effects of Testosterone Supplementation for 3-Years on Muscle Performance and Physical Function in Older Men. J Clin Endocrinol Metab (2016) 0.75
Androgen Therapy and Rehospitalization in Older Men With Testosterone Deficiency. Mayo Clin Proc (2016) 0.75
Skeletal muscle strength as a predictor of all-cause mortality in healthy men. J Gerontol A Biol Sci Med Sci (2002) 3.56
Growth hormone and sex steroid administration in healthy aged women and men: a randomized controlled trial. JAMA (2002) 3.36
Hypercortisolemic depression is associated with the metabolic syndrome in late-life. Psychoneuroendocrinology (2007) 2.98
Arterial imaging outcomes and cardiovascular risk factors in recently menopausal women: a randomized trial. Ann Intern Med (2014) 2.48
Biomarkers of caloric restriction may predict longevity in humans. Science (2002) 2.32
Serum levels of insulin-like growth factor-I (IGF-I) and dehydroepiandrosterone sulfate (DHEA-S), and their relationships with serum interleukin-6, in the geriatric syndrome of frailty. Aging Clin Exp Res (2004) 2.17
Longitudinal assessment of serum free testosterone concentration predicts memory performance and cognitive status in elderly men. J Clin Endocrinol Metab (2002) 1.70
Aging, androgens, and the metabolic syndrome in a longitudinal study of aging. J Clin Endocrinol Metab (2007) 1.70
Falls in young, middle-aged and older community dwelling adults: perceived cause, environmental factors and injury. BMC Public Health (2005) 1.62
Women, hormones, and clinical trials: a beginning, not an end. J Appl Physiol (1985) (2005) 1.60
Health behaviors and risk factors in those who use complementary and alternative medicine. BMC Public Health (2007) 1.57
Is there an antiaging medicine? J Gerontol A Biol Sci Med Sci (2002) 1.46
Characterization of blood borne microparticles as markers of premature coronary calcification in newly menopausal women. Am J Physiol Heart Circ Physiol (2008) 1.44
Biomarkers of aging: from primitive organisms to humans. J Gerontol A Biol Sci Med Sci (2004) 1.44
Low bone mass in premenopausal women with depression. Arch Intern Med (2007) 1.38
Bone mineral density and osteoarthritis: data from the Baltimore Longitudinal Study of Aging. Osteoarthritis Cartilage (2004) 1.32
Brx mediates the response of lymphocytes to osmotic stress through the activation of NFAT5. Sci Signal (2009) 1.30
Comparative effects of DHEA vs. testosterone, dihydrotestosterone, and estradiol on proliferation and gene expression in human LNCaP prostate cancer cells. Am J Physiol Endocrinol Metab (2004) 1.24
Mitochondria as key components of the stress response. Trends Endocrinol Metab (2007) 1.23
Postmenopausal hormone therapy: new questions and the case for new clinical trials. Menopause (2006) 1.18
Higher serum testosterone concentration in older women is associated with insulin resistance, metabolic syndrome, and cardiovascular disease. J Clin Endocrinol Metab (2009) 1.16
Higher serum free testosterone concentration in older women is associated with greater bone mineral density, lean body mass, and total fat mass: the cardiovascular health study. J Clin Endocrinol Metab (2011) 1.15
Effects of an oral growth hormone secretagogue in older adults. J Clin Endocrinol Metab (2009) 1.13
Alterations in platelet function and cell-derived microvesicles in recently menopausal women: relationship to metabolic syndrome and atherogenic risk. J Cardiovasc Transl Res (2011) 1.11
Arm-cranking muscle power and arm isometric muscle strength are independent predictors of all-cause mortality in men. J Appl Physiol (1985) (2003) 1.10
Exercise capacity and all-cause mortality in African American and Caucasian men with type 2 diabetes. Diabetes Care (2009) 1.08
Use of growth hormone secretagogues to prevent or treat the effects of aging: not yet ready for prime time. Ann Intern Med (2008) 1.07
Tart cherry juice decreases oxidative stress in healthy older men and women. J Nutr (2009) 1.04
Quantification of 8-iso-prostaglandin-F(2alpha) and 2,3-dinor-8-iso-prostaglandin-F(2alpha) in human urine using liquid chromatography-tandem mass spectrometry. Free Radic Biol Med (2003) 1.03
DHT and testosterone, but not DHEA or E2, differentially modulate IGF-I, IGFBP-2, and IGFBP-3 in human prostatic stromal cells. Am J Physiol Endocrinol Metab (2005) 1.03
Third-generation human mitochondria-focused cDNA microarray and its bioinformatic tools for analysis of gene expression. Biotechniques (2007) 1.03
Androgen receptor or estrogen receptor-beta blockade alters DHEA-, DHT-, and E(2)-induced proliferation and PSA production in human prostate cancer cells. Prostate (2007) 1.01
Clinical subtypes of depression are associated with specific metabolic parameters and circadian endocrine profiles in women: the power study. PLoS One (2012) 1.01
Monoamine oxidase-A is a major target gene for glucocorticoids in human skeletal muscle cells. FASEB J (2005) 1.01
Intra-thoracic fat, cardiometabolic risk factors, and subclinical cardiovascular disease in healthy, recently menopausal women screened for the Kronos Early Estrogen Prevention Study (KEEPS). Atherosclerosis (2011) 0.99
Human prostate stromal cells stimulate increased PSA production in DHEA-treated prostate cancer epithelial cells. J Steroid Biochem Mol Biol (2008) 0.99
Use of growth hormone for prevention or treatment of effects of aging. J Gerontol A Biol Sci Med Sci (2004) 0.97
Low 24-hour adiponectin and high nocturnal leptin concentrations in a case-control study of community-dwelling premenopausal women with major depressive disorder: the Premenopausal, Osteopenia/Osteoporosis, Women, Alendronate, Depression (POWER) study. J Clin Psychiatry (2010) 0.96
Determinants of serum total and free testosterone levels in women over the age of 65 years. J Clin Endocrinol Metab (2006) 0.96
Relationship between androgenic hormones and arterial stiffness, based on longitudinal hormone measurements. Am J Physiol Endocrinol Metab (2005) 0.95
Lycopene inhibits IGF-I signal transduction and growth in normal prostate epithelial cells by decreasing DHT-modulated IGF-I production in co-cultured reactive stromal cells. Carcinogenesis (2008) 0.95
Genetic polymorphisms associated with carotid artery intima-media thickness and coronary artery calcification in women of the Kronos Early Estrogen Prevention Study. Physiol Genomics (2012) 0.93
The Women's Health Initiative could not have detected cardioprotective effects of starting hormone therapy during the menopausal transition. Fertil Steril (2004) 0.93
The effects of growth hormone and sex steroid on lean body mass, fat mass, muscle strength, cardiovascular endurance and adverse events in healthy elderly women and men. Horm Res (2003) 0.91
Oxidative stress in older adults: effects of physical fitness. Age (Dordr) (2011) 0.91
Werner syndrome protein 1367 variants and disposition towards coronary artery disease in Caucasian patients. Mech Ageing Dev (2004) 0.90
Effects of chronic osteoarthritis pain on neuroendocrine function in men. J Clin Endocrinol Metab (2006) 0.90
Antibody-directed neutralization of annexin II (ANX II) inhibits neoangiogenesis and human breast tumor growth in a xenograft model. Exp Mol Pathol (2011) 0.89
Effects of GH and/or sex steroids on circulating IGF-I and IGFBPs in healthy, aged women and men. Am J Physiol Endocrinol Metab (2006) 0.88
Ischemia/reperfusion unveils impaired capacity of older adults to restrain oxidative insult. Free Radic Biol Med (2009) 0.87
Endocrine-immune-paracrine interactions in prostate cells as targeted by phytomedicines. Cancer Prev Res (Phila) (2009) 0.85
The application of umbilical cord blood cells in the treatment of diabetes mellitus. Rev Diabet Stud (2006) 0.85
Vinegar lacks antiglycemic action on enteral carbohydrate absorption in human subjects. Nutr Res (2009) 0.85
Tolerance, fermentation, and cytokine expression in healthy aged male C57BL/6J mice fed resistant starch. Mol Nutr Food Res (2011) 0.84
Dietary whey protein decreases food intake and body fat in rats. Obesity (Silver Spring) (2011) 0.84
Self-reported menopausal symptoms, coronary artery calcification, and carotid intima-media thickness in recently menopausal women screened for the Kronos early estrogen prevention study (KEEPS). Fertil Steril (2013) 0.83
High-dose statin use does not impair aerobic capacity or skeletal muscle function in older adults. Age (Dordr) (2008) 0.83
Physiological correlates of age-related decline in vibrotactile sensitivity. Neurobiol Aging (2007) 0.83
Predicting cardiovascular risk using measures of regional and total body fat. Appl Nurs Res (2009) 0.83
Long-term testosterone supplementation augments overnight growth hormone secretion in healthy older men. Am J Physiol Endocrinol Metab (2007) 0.83
NCCAM/NCI Phase 1 Study of Mistletoe Extract and Gemcitabine in Patients with Advanced Solid Tumors. Evid Based Complement Alternat Med (2013) 0.81
Masculine vitality: pros and cons of testosterone in treating the andropause. J Gerontol A Biol Sci Med Sci (2004) 0.81
Complementary and alternative medicine (CAM). Geriatr Nurs (2009) 0.80
Characterization of vascular disease risk in postmenopausal women and its association with cognitive performance. PLoS One (2013) 0.80
Effects of growth hormone and/or sex steroid administration on whole-body protein turnover in healthy aged women and men. Metabolism (2005) 0.80
Does DHEA exert direct effects on androgen and estrogen receptors, and does it promote or prevent prostate cancer? Endocrinology (2005) 0.79
The role of carnitine in the male reproductive system. Ann N Y Acad Sci (2004) 0.79
Mistletoe and gemcitabine in patients with advanced cancer: a model for the phase I study of botanicals and botanical-drug interactions in cancer therapy. Integr Cancer Ther (2003) 0.79
Growth hormone and sex steroid effects on bone metabolism and bone mineral density in healthy aged women and men. J Gerontol A Biol Sci Med Sci (2002) 0.78
Relation of aggressiveness of lipid-lowering treatment to changes in calcified plaque burden by electron beam tomography. Am J Cardiol (2003) 0.78
Dietary resistant starch improves selected brain and behavioral functions in adult and aged rodents. Mol Nutr Food Res (2013) 0.78
Can menopausal hormone therapy prevent coronary heart disease? Trends Endocrinol Metab (2008) 0.78
Growth hormone and sex steroid effects on serum glucose, insulin, and lipid concentrations in healthy older women and men. J Clin Endocrinol Metab (2009) 0.77
L-Carnitine and acetyl-L-carnitine in the treatment of complications associated with HIV infection and antiretroviral therapy. Mitochondrion (2004) 0.77
Effects of testosterone administration on nocturnal cortisol secretion in healthy older men. J Gerontol A Biol Sci Med Sci (2010) 0.77
Dehydroepiandrosterone secretion in healthy older men and women: effects of testosterone and growth hormone administration in older men. J Clin Endocrinol Metab (2006) 0.77
Challenges to be overcome using population-based sampling methods to recruit veterans for a study of post-traumatic stress disorder and traumatic brain injury. BMC Med Res Methodol (2014) 0.77
Comparative effects of DHEA and DHT on gene expression in human LNCaP prostate cancer cells. Anticancer Res (2006) 0.77
Comparison of the effects of atorvastatin versus simvastatin on subclinical atherosclerosis in primary preventionas determined by electronbeam tomography. Am J Cardiol (2003) 0.76
What can we learn from design faults in the Women's Health Initiative randomized clinical trial? Bull NYU Hosp Jt Dis (2009) 0.76
Manipulation of the growth hormone axis in patients with HIV infection. N Engl J Med (2007) 0.76
Evaluation by electron beam tomography of changes in calcified coronary plaque in treated and untreated asymptomatic patients and relation to serum lipid levels. Am J Cardiol (2003) 0.76
Growth hormone should be used only for approved indications. J Clin Endocrinol Metab (2013) 0.76
Antiaging technology and pseudoscience. Science (2002) 0.75
Menopausal hormone therapy and risk for cardiovascular disease in the WHI trial. Ann Intern Med (2010) 0.75
Preventing Alzheimer disease and cognitive decline. Ann Intern Med (2011) 0.75