Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation.
|
Nature
|
2002
|
19.77
|
2
|
Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion.
|
EMBO J
|
2003
|
6.46
|
3
|
The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway.
|
EMBO Rep
|
2002
|
4.76
|
4
|
Endogenous HMGB1 regulates autophagy.
|
J Cell Biol
|
2010
|
4.71
|
5
|
Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures.
|
Nat Med
|
2010
|
4.61
|
6
|
HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses.
|
Nature
|
2009
|
3.86
|
7
|
High-mobility group box-1 in ischemia-reperfusion injury of the heart.
|
Circulation
|
2008
|
3.46
|
8
|
Glycyrrhizin binds to high-mobility group box 1 protein and inhibits its cytokine activities.
|
Chem Biol
|
2007
|
3.12
|
9
|
A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA.
|
Blood
|
2007
|
3.09
|
10
|
Release of high mobility group box 1 by dendritic cells controls T cell activation via the receptor for advanced glycation end products.
|
J Immunol
|
2005
|
3.05
|
11
|
HMGB1 is an endogenous immune adjuvant released by necrotic cells.
|
EMBO Rep
|
2004
|
3.00
|
12
|
Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: implications for the pathogenesis of SLE.
|
J Exp Med
|
2008
|
2.97
|
13
|
Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release.
|
J Exp Med
|
2012
|
2.89
|
14
|
Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1).
|
Mol Med
|
2012
|
2.79
|
15
|
Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation.
|
J Cell Biol
|
2004
|
2.75
|
16
|
HMGB proteins and gene expression.
|
Curr Opin Genet Dev
|
2003
|
2.55
|
17
|
A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10).
|
FASEB J
|
2008
|
2.51
|
18
|
A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin.
|
EMBO J
|
2007
|
2.44
|
19
|
HMGB1: guiding immunity from within.
|
Trends Immunol
|
2005
|
2.42
|
20
|
A hyper-dynamic equilibrium between promoter-bound and nucleoplasmic dimers controls NF-kappaB-dependent gene activity.
|
EMBO J
|
2006
|
2.41
|
21
|
Exogenous high-mobility group box 1 protein induces myocardial regeneration after infarction via enhanced cardiac C-kit+ cell proliferation and differentiation.
|
Circ Res
|
2005
|
2.32
|
22
|
Substantial histone reduction modulates genomewide nucleosomal occupancy and global transcriptional output.
|
PLoS Biol
|
2011
|
2.26
|
23
|
Cells migrating to sites of tissue damage in response to the danger signal HMGB1 require NF-kappaB activation.
|
J Cell Biol
|
2007
|
1.98
|
24
|
The DNA chaperone HMGB1 facilitates ACF/CHRAC-dependent nucleosome sliding.
|
EMBO J
|
2002
|
1.91
|
25
|
High-mobility group box 1 activates integrin-dependent homing of endothelial progenitor cells.
|
Circ Res
|
2007
|
1.89
|
26
|
Sustained oscillations of NF-kappaB produce distinct genome scanning and gene expression profiles.
|
PLoS One
|
2009
|
1.81
|
27
|
Treatment with HMGB1 inhibitors diminishes CTL-induced liver disease in HBV transgenic mice.
|
J Leukoc Biol
|
2006
|
1.73
|
28
|
Programmed necrosis induced by asbestos in human mesothelial cells causes high-mobility group box 1 protein release and resultant inflammation.
|
Proc Natl Acad Sci U S A
|
2010
|
1.72
|
29
|
Requirement of HMGB1 and RAGE for the maturation of human plasmacytoid dendritic cells.
|
Eur J Immunol
|
2005
|
1.63
|
30
|
Cancer cell secretion of the DAMP protein HMGB1 supports progression in malignant mesothelioma.
|
Cancer Res
|
2012
|
1.61
|
31
|
The secretion of HMGB1 is required for the migration of maturing dendritic cells.
|
J Leukoc Biol
|
2006
|
1.53
|
32
|
Inflammatory and alternatively activated human macrophages attract vessel-associated stem cells, relying on separate HMGB1- and MMP-9-dependent pathways.
|
J Leukoc Biol
|
2009
|
1.51
|
33
|
Smooth muscle cells in human atherosclerotic plaques secrete and proliferate in response to high mobility group box 1 protein.
|
FASEB J
|
2006
|
1.50
|
34
|
Association of chromatin proteins high mobility group box (HMGB) 1 and HMGB2 with mitotic chromosomes.
|
Mol Biol Cell
|
2003
|
1.43
|
35
|
Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis.
|
Proc Natl Acad Sci U S A
|
2009
|
1.39
|
36
|
TLR4-mediated skin carcinogenesis is dependent on immune and radioresistant cells.
|
EMBO J
|
2010
|
1.37
|
37
|
High-mobility group box 1 protein in human and murine skin: involvement in wound healing.
|
J Invest Dermatol
|
2008
|
1.36
|
38
|
Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis.
|
PLoS Pathog
|
2011
|
1.34
|
39
|
GR and HMGB1 interact only within chromatin and influence each other's residence time.
|
Mol Cell
|
2005
|
1.32
|
40
|
Maturing dendritic cells depend on RAGE for in vivo homing to lymph nodes.
|
J Immunol
|
2008
|
1.32
|
41
|
HMGB1: a signal of necrosis.
|
Autoimmunity
|
2007
|
1.28
|
42
|
A nuclear protein complex containing high mobility group proteins B1 and B2, heat shock cognate protein 70, ERp60, and glyceraldehyde-3-phosphate dehydrogenase is involved in the cytotoxic response to DNA modified by incorporation of anticancer nucleoside analogues.
|
Cancer Res
|
2003
|
1.27
|
43
|
Inhibitor of NF-kappa B kinases alpha and beta are both essential for high mobility group box 1-mediated chemotaxis [corrected].
|
J Immunol
|
2010
|
1.27
|
44
|
Yeast Nhp6A/B and mammalian Hmgb1 facilitate the maintenance of genome stability.
|
Curr Biol
|
2005
|
1.24
|
45
|
The long acidic tail of high mobility group box 1 (HMGB1) protein forms an extended and flexible structure that interacts with specific residues within and between the HMG boxes.
|
Biochemistry
|
2004
|
1.24
|
46
|
HMGB1 and leukocyte migration during trauma and sterile inflammation.
|
Mol Immunol
|
2012
|
1.21
|
47
|
Requirement of HMGB1 for stromal cell-derived factor-1/CXCL12-dependent migration of macrophages and dendritic cells.
|
J Leukoc Biol
|
2009
|
1.21
|
48
|
High mobility group box 1 protein, a cue for stem cell recruitment.
|
Biochem Pharmacol
|
2004
|
1.16
|
49
|
Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification.
|
Mol Cell Biol
|
2007
|
1.15
|
50
|
Multiple effects of high mobility group box protein 1 in skeletal muscle regeneration.
|
Arterioscler Thromb Vasc Biol
|
2007
|
1.14
|
51
|
HMGB1 interacts differentially with members of the Rel family of transcription factors.
|
Biochem Biophys Res Commun
|
2003
|
1.12
|
52
|
Protective targeting of high mobility group box chromosomal protein 1 in a spontaneous arthritis model.
|
Arthritis Rheum
|
2010
|
1.10
|
53
|
HMGB1, an architectural chromatin protein and extracellular signalling factor, has a spatially and temporally restricted expression pattern in mouse brain.
|
Gene Expr Patterns
|
2003
|
1.09
|
54
|
Src family kinases are necessary for cell migration induced by extracellular HMGB1.
|
J Leukoc Biol
|
2009
|
1.06
|
55
|
Disulfide-containing high mobility group box-1 promotes N-methyl-D-aspartate receptor function and excitotoxicity by activating Toll-like receptor 4-dependent signaling in hippocampal neurons.
|
Antioxid Redox Signal
|
2014
|
1.00
|
56
|
HMGB1: the missing link between diabetes mellitus and heart failure.
|
Basic Res Cardiol
|
2010
|
0.98
|
57
|
Regulation of dendritic- and T-cell fate by injury-associated endogenous signals.
|
Crit Rev Immunol
|
2009
|
0.97
|
58
|
Oxidative stress elicits platelet/leukocyte inflammatory interactions via HMGB1: a candidate for microvessel injury in sytemic sclerosis.
|
Antioxid Redox Signal
|
2014
|
0.96
|
59
|
Redox remodeling: a candidate regulator of HMGB1 function in injured skeletal muscle.
|
Ann N Y Acad Sci
|
2010
|
0.95
|
60
|
Receptor for Advanced Glycation Endproducts is upregulated in temporal lobe epilepsy and contributes to experimental seizures.
|
Neurobiol Dis
|
2013
|
0.90
|
61
|
HuR and miR-1192 regulate myogenesis by modulating the translation of HMGB1 mRNA.
|
Nat Commun
|
2013
|
0.88
|
62
|
Damage associated molecular pattern molecule-induced microRNAs (DAMPmiRs) in human peripheral blood mononuclear cells.
|
PLoS One
|
2012
|
0.87
|
63
|
Ku70/Ku80 and DNA-dependent protein kinase catalytic subunit modulate RAG-mediated cleavage: implications for the enforcement of the 12/23 rule.
|
J Biol Chem
|
2004
|
0.86
|
64
|
The evolution of High Mobility Group Box (HMGB) chromatin proteins in multicellular animals.
|
Gene
|
2006
|
0.86
|
65
|
High mobility group B2 is secreted by myeloid cells and has mitogenic and chemoattractant activities similar to high mobility group B1.
|
Autoimmunity
|
2009
|
0.85
|
66
|
Sexy splicing: regulatory interplays governing sex determination from Drosophila to mammals.
|
J Cell Sci
|
2003
|
0.83
|
67
|
5-Fluorouracil causes leukocytes attraction in the peritoneal cavity by activating autophagy and HMGB1 release in colon carcinoma cells.
|
Int J Cancer
|
2014
|
0.82
|
68
|
Editorial: A recipe for inflammation.
|
J Leukoc Biol
|
2009
|
0.78
|
69
|
DNA-based strategies for blocking HMGB1 cytokine activity: design, synthesis and preliminary in vitro/in vivo assays of DNA and DNA-like duplexes.
|
Mol Biosyst
|
2011
|
0.77
|
70
|
HMGB1: An immmune odyssey.
|
Discov Med
|
2005
|
0.77
|