Marco E Bianchi

Author PubWeight™ 143.79‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 2002 19.77
2 Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion. EMBO J 2003 6.46
3 The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway. EMBO Rep 2002 4.76
4 Endogenous HMGB1 regulates autophagy. J Cell Biol 2010 4.71
5 Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures. Nat Med 2010 4.61
6 HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses. Nature 2009 3.86
7 High-mobility group box-1 in ischemia-reperfusion injury of the heart. Circulation 2008 3.46
8 Glycyrrhizin binds to high-mobility group box 1 protein and inhibits its cytokine activities. Chem Biol 2007 3.12
9 A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA. Blood 2007 3.09
10 Release of high mobility group box 1 by dendritic cells controls T cell activation via the receptor for advanced glycation end products. J Immunol 2005 3.05
11 HMGB1 is an endogenous immune adjuvant released by necrotic cells. EMBO Rep 2004 3.00
12 Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: implications for the pathogenesis of SLE. J Exp Med 2008 2.97
13 Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release. J Exp Med 2012 2.89
14 Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1). Mol Med 2012 2.79
15 Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation. J Cell Biol 2004 2.75
16 HMGB proteins and gene expression. Curr Opin Genet Dev 2003 2.55
17 A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10). FASEB J 2008 2.51
18 A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin. EMBO J 2007 2.44
19 HMGB1: guiding immunity from within. Trends Immunol 2005 2.42
20 A hyper-dynamic equilibrium between promoter-bound and nucleoplasmic dimers controls NF-kappaB-dependent gene activity. EMBO J 2006 2.41
21 Exogenous high-mobility group box 1 protein induces myocardial regeneration after infarction via enhanced cardiac C-kit+ cell proliferation and differentiation. Circ Res 2005 2.32
22 Substantial histone reduction modulates genomewide nucleosomal occupancy and global transcriptional output. PLoS Biol 2011 2.26
23 Cells migrating to sites of tissue damage in response to the danger signal HMGB1 require NF-kappaB activation. J Cell Biol 2007 1.98
24 The DNA chaperone HMGB1 facilitates ACF/CHRAC-dependent nucleosome sliding. EMBO J 2002 1.91
25 High-mobility group box 1 activates integrin-dependent homing of endothelial progenitor cells. Circ Res 2007 1.89
26 Sustained oscillations of NF-kappaB produce distinct genome scanning and gene expression profiles. PLoS One 2009 1.81
27 Treatment with HMGB1 inhibitors diminishes CTL-induced liver disease in HBV transgenic mice. J Leukoc Biol 2006 1.73
28 Programmed necrosis induced by asbestos in human mesothelial cells causes high-mobility group box 1 protein release and resultant inflammation. Proc Natl Acad Sci U S A 2010 1.72
29 Requirement of HMGB1 and RAGE for the maturation of human plasmacytoid dendritic cells. Eur J Immunol 2005 1.63
30 Cancer cell secretion of the DAMP protein HMGB1 supports progression in malignant mesothelioma. Cancer Res 2012 1.61
31 The secretion of HMGB1 is required for the migration of maturing dendritic cells. J Leukoc Biol 2006 1.53
32 Inflammatory and alternatively activated human macrophages attract vessel-associated stem cells, relying on separate HMGB1- and MMP-9-dependent pathways. J Leukoc Biol 2009 1.51
33 Smooth muscle cells in human atherosclerotic plaques secrete and proliferate in response to high mobility group box 1 protein. FASEB J 2006 1.50
34 Association of chromatin proteins high mobility group box (HMGB) 1 and HMGB2 with mitotic chromosomes. Mol Biol Cell 2003 1.43
35 Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis. Proc Natl Acad Sci U S A 2009 1.39
36 TLR4-mediated skin carcinogenesis is dependent on immune and radioresistant cells. EMBO J 2010 1.37
37 High-mobility group box 1 protein in human and murine skin: involvement in wound healing. J Invest Dermatol 2008 1.36
38 Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis. PLoS Pathog 2011 1.34
39 GR and HMGB1 interact only within chromatin and influence each other's residence time. Mol Cell 2005 1.32
40 Maturing dendritic cells depend on RAGE for in vivo homing to lymph nodes. J Immunol 2008 1.32
41 HMGB1: a signal of necrosis. Autoimmunity 2007 1.28
42 A nuclear protein complex containing high mobility group proteins B1 and B2, heat shock cognate protein 70, ERp60, and glyceraldehyde-3-phosphate dehydrogenase is involved in the cytotoxic response to DNA modified by incorporation of anticancer nucleoside analogues. Cancer Res 2003 1.27
43 Inhibitor of NF-kappa B kinases alpha and beta are both essential for high mobility group box 1-mediated chemotaxis [corrected]. J Immunol 2010 1.27
44 Yeast Nhp6A/B and mammalian Hmgb1 facilitate the maintenance of genome stability. Curr Biol 2005 1.24
45 The long acidic tail of high mobility group box 1 (HMGB1) protein forms an extended and flexible structure that interacts with specific residues within and between the HMG boxes. Biochemistry 2004 1.24
46 HMGB1 and leukocyte migration during trauma and sterile inflammation. Mol Immunol 2012 1.21
47 Requirement of HMGB1 for stromal cell-derived factor-1/CXCL12-dependent migration of macrophages and dendritic cells. J Leukoc Biol 2009 1.21
48 High mobility group box 1 protein, a cue for stem cell recruitment. Biochem Pharmacol 2004 1.16
49 Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification. Mol Cell Biol 2007 1.15
50 Multiple effects of high mobility group box protein 1 in skeletal muscle regeneration. Arterioscler Thromb Vasc Biol 2007 1.14
51 HMGB1 interacts differentially with members of the Rel family of transcription factors. Biochem Biophys Res Commun 2003 1.12
52 Protective targeting of high mobility group box chromosomal protein 1 in a spontaneous arthritis model. Arthritis Rheum 2010 1.10
53 HMGB1, an architectural chromatin protein and extracellular signalling factor, has a spatially and temporally restricted expression pattern in mouse brain. Gene Expr Patterns 2003 1.09
54 Src family kinases are necessary for cell migration induced by extracellular HMGB1. J Leukoc Biol 2009 1.06
55 Disulfide-containing high mobility group box-1 promotes N-methyl-D-aspartate receptor function and excitotoxicity by activating Toll-like receptor 4-dependent signaling in hippocampal neurons. Antioxid Redox Signal 2014 1.00
56 HMGB1: the missing link between diabetes mellitus and heart failure. Basic Res Cardiol 2010 0.98
57 Regulation of dendritic- and T-cell fate by injury-associated endogenous signals. Crit Rev Immunol 2009 0.97
58 Oxidative stress elicits platelet/leukocyte inflammatory interactions via HMGB1: a candidate for microvessel injury in sytemic sclerosis. Antioxid Redox Signal 2014 0.96
59 Redox remodeling: a candidate regulator of HMGB1 function in injured skeletal muscle. Ann N Y Acad Sci 2010 0.95
60 Receptor for Advanced Glycation Endproducts is upregulated in temporal lobe epilepsy and contributes to experimental seizures. Neurobiol Dis 2013 0.90
61 HuR and miR-1192 regulate myogenesis by modulating the translation of HMGB1 mRNA. Nat Commun 2013 0.88
62 Damage associated molecular pattern molecule-induced microRNAs (DAMPmiRs) in human peripheral blood mononuclear cells. PLoS One 2012 0.87
63 Ku70/Ku80 and DNA-dependent protein kinase catalytic subunit modulate RAG-mediated cleavage: implications for the enforcement of the 12/23 rule. J Biol Chem 2004 0.86
64 The evolution of High Mobility Group Box (HMGB) chromatin proteins in multicellular animals. Gene 2006 0.86
65 High mobility group B2 is secreted by myeloid cells and has mitogenic and chemoattractant activities similar to high mobility group B1. Autoimmunity 2009 0.85
66 Sexy splicing: regulatory interplays governing sex determination from Drosophila to mammals. J Cell Sci 2003 0.83
67 5-Fluorouracil causes leukocytes attraction in the peritoneal cavity by activating autophagy and HMGB1 release in colon carcinoma cells. Int J Cancer 2014 0.82
68 Editorial: A recipe for inflammation. J Leukoc Biol 2009 0.78
69 DNA-based strategies for blocking HMGB1 cytokine activity: design, synthesis and preliminary in vitro/in vivo assays of DNA and DNA-like duplexes. Mol Biosyst 2011 0.77
70 HMGB1: An immmune odyssey. Discov Med 2005 0.77