| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
The receptor of advanced glycation end products plays a central role in advanced oxidation protein products-induced podocyte apoptosis.
|
Kidney Int
|
2012
|
1.77
|
|
2
|
Plasminogen activator inhibitor-1 antagonist TM5441 attenuates Nω-nitro-L-arginine methyl ester-induced hypertension and vascular senescence.
|
Circulation
|
2013
|
1.76
|
|
3
|
Effect of sevelamer and calcium-based phosphate binders on coronary artery calcification and accumulation of circulating advanced glycation end products in hemodialysis patients.
|
Am J Kidney Dis
|
2011
|
1.69
|
|
4
|
Renoprotective properties of angiotensin receptor blockers beyond blood pressure lowering.
|
J Am Soc Nephrol
|
2005
|
1.64
|
|
5
|
Evidence of tubular hypoxia in the early phase in the remnant kidney model.
|
J Am Soc Nephrol
|
2004
|
1.52
|
|
6
|
Metallothionein is upregulated by hypoxia and stabilizes hypoxia-inducible factor in the kidney.
|
Kidney Int
|
2008
|
1.52
|
|
7
|
Imbalance of T-cell subsets in angiotensin II-infused hypertensive rats with kidney injury.
|
Hypertension
|
2003
|
1.40
|
|
8
|
Transdifferentiation of cultured tubular cells induced by hypoxia.
|
Kidney Int
|
2004
|
1.36
|
|
9
|
Protective role of hypoxia-inducible factor-2alpha against ischemic damage and oxidative stress in the kidney.
|
J Am Soc Nephrol
|
2007
|
1.35
|
|
10
|
A novel class of prolyl hydroxylase inhibitors induces angiogenesis and exerts organ protection against ischemia.
|
Arterioscler Thromb Vasc Biol
|
2007
|
1.34
|
|
11
|
Cobalt ameliorates renal injury in an obese, hypertensive type 2 diabetes rat model.
|
Nephrol Dial Transplant
|
2007
|
1.30
|
|
12
|
Overexpression of glyoxalase-I reduces hyperglycemia-induced levels of advanced glycation end products and oxidative stress in diabetic rats.
|
J Biol Chem
|
2010
|
1.27
|
|
13
|
Inhibition of plasminogen activator inhibitor-1: its mechanism and effectiveness on coagulation and fibrosis.
|
Arterioscler Thromb Vasc Biol
|
2008
|
1.26
|
|
14
|
Hypoxia and hypoxia-inducible factor in renal disease.
|
Nephron Exp Nephrol
|
2008
|
1.26
|
|
15
|
Induction of protective genes by cobalt ameliorates tubulointerstitial injury in the progressive Thy1 nephritis.
|
Kidney Int
|
2005
|
1.24
|
|
16
|
Involvement of endoplasmic reticulum (ER) stress in podocyte injury induced by excessive protein accumulation.
|
Kidney Int
|
2005
|
1.14
|
|
17
|
Skin autofluorescence, a marker for advanced glycation end product accumulation, is associated with arterial stiffness in patients with end-stage renal disease.
|
Metabolism
|
2008
|
1.10
|
|
18
|
Hypoperfusion of peritubular capillaries induces chronic hypoxia before progression of tubulointerstitial injury in a progressive model of rat glomerulonephritis.
|
J Am Soc Nephrol
|
2004
|
1.09
|
|
19
|
A biologic role of HIF-1 in the renal medulla.
|
Kidney Int
|
2005
|
1.09
|
|
20
|
A novel inhibitor of plasminogen activator inhibitor-1 provides antithrombotic benefits devoid of bleeding effect in nonhuman primates.
|
J Cereb Blood Flow Metab
|
2010
|
1.09
|
|
21
|
Methylglyoxal is a predictor in type 2 diabetic patients of intima-media thickening and elevation of blood pressure.
|
Hypertension
|
2010
|
1.09
|
|
22
|
Enhanced expression of receptor for advanced glycation end products in chronic kidney disease.
|
J Am Soc Nephrol
|
2004
|
1.08
|
|
23
|
Anti-hypertensive agents inhibit in vivo the formation of advanced glycation end products and improve renal damage in a type 2 diabetic nephropathy rat model.
|
J Am Soc Nephrol
|
2003
|
1.08
|
|
24
|
High glucose blunts vascular endothelial growth factor response to hypoxia via the oxidative stress-regulated hypoxia-inducible factor/hypoxia-responsible element pathway.
|
J Am Soc Nephrol
|
2006
|
1.06
|
|
25
|
Therapeutic value of small molecule inhibitor to plasminogen activator inhibitor-1 for lung fibrosis.
|
Am J Respir Cell Mol Biol
|
2012
|
1.06
|
|
26
|
Lipid peroxidation and advanced glycation end products in the brain in normal aging and in Alzheimer's disease.
|
Acta Neuropathol
|
2002
|
1.05
|
|
27
|
Hypoxia-inducible factor modulates tubular cell survival in cisplatin nephrotoxicity.
|
Am J Physiol Renal Physiol
|
2005
|
1.05
|
|
28
|
Efficient in vitro lowering of carbonyl stress by the glyoxalase system in conventional glucose peritoneal dialysis fluid.
|
Kidney Int
|
2002
|
1.02
|
|
29
|
Erythropoietin induces heme oxygenase-1 expression and attenuates oxidative stress.
|
Biochem Biophys Res Commun
|
2007
|
1.01
|
|
30
|
Hypoxia-induced apoptosis in cultured glomerular endothelial cells: involvement of mitochondrial pathways.
|
Kidney Int
|
2003
|
1.00
|
|
31
|
Enhanced carbonyl stress in a subpopulation of schizophrenia.
|
Arch Gen Psychiatry
|
2010
|
0.99
|
|
32
|
Glyoxalase I overexpression ameliorates renal ischemia-reperfusion injury in rats.
|
Am J Physiol Renal Physiol
|
2009
|
0.99
|
|
33
|
Inhibition of PAI-1 induces neutrophil-driven neoangiogenesis and promotes tissue regeneration via production of angiocrine factors in mice.
|
Blood
|
2012
|
0.99
|
|
34
|
Inhibition of prolyl hydroxylase domain-containing protein suppressed lipopolysaccharide-induced TNF-alpha expression.
|
Arterioscler Thromb Vasc Biol
|
2009
|
0.98
|
|
35
|
Skin autofluorescence is associated with renal function and cardiovascular diseases in pre-dialysis chronic kidney disease patients.
|
Nephrol Dial Transplant
|
2010
|
0.97
|
|
36
|
Methylglyoxal contributes to the development of insulin resistance and salt sensitivity in Sprague-Dawley rats.
|
J Hypertens
|
2009
|
0.97
|
|
37
|
Preconditioning with endoplasmic reticulum stress ameliorates mesangioproliferative glomerulonephritis.
|
J Am Soc Nephrol
|
2008
|
0.96
|
|
38
|
Carbonyl stress induces hypertension and cardio-renal vascular injury in Dahl salt-sensitive rats.
|
Hypertens Res
|
2013
|
0.96
|
|
39
|
A severe diabetic nephropathy model with early development of nodule-like lesions induced by megsin overexpression in RAGE/iNOS transgenic mice.
|
Diabetes
|
2006
|
0.96
|
|
40
|
In a type 2 diabetic nephropathy rat model, the improvement of obesity by a low calorie diet reduces oxidative/carbonyl stress and prevents diabetic nephropathy.
|
Nephrol Dial Transplant
|
2005
|
0.96
|
|
41
|
Measurement of advanced glycation endproducts in skin of patients with rheumatoid arthritis, osteoarthritis, and dialysis-related spondyloarthropathy using non-invasive methods.
|
Rheumatol Int
|
2007
|
0.93
|
|
42
|
Hypoxia in renal disease with proteinuria and/or glomerular hypertension.
|
Am J Pathol
|
2004
|
0.93
|
|
43
|
Glyoxalase I reduces glycative and oxidative stress and prevents age-related endothelial dysfunction through modulation of endothelial nitric oxide synthase phosphorylation.
|
Aging Cell
|
2014
|
0.92
|
|
44
|
Evidence for oxidative stress in NSAID-induced colitis in IL10-/- mice.
|
Free Radic Biol Med
|
2003
|
0.91
|
|
45
|
A small molecule inhibitor to plasminogen activator inhibitor 1 inhibits macrophage migration.
|
Arterioscler Thromb Vasc Biol
|
2013
|
0.91
|
|
46
|
Kidney failure: aims for the next 10 years and barriers to success.
|
Lancet
|
2013
|
0.91
|
|
47
|
Blockade of calcium influx through L-type calcium channels attenuates mitochondrial injury and apoptosis in hypoxic renal tubular cells.
|
J Am Soc Nephrol
|
2004
|
0.91
|
|
48
|
Skin-autofluorescence, a measure of tissue advanced glycation end-products (AGEs), is related to diastolic function in dialysis patients.
|
J Card Fail
|
2008
|
0.90
|
|
49
|
Early- and advanced non-enzymatic glycation in diabetic vascular complications: the search for therapeutics.
|
Amino Acids
|
2010
|
0.90
|
|
50
|
Novel serpinopathy in rat kidney and pancreas induced by overexpression of megsin.
|
J Am Soc Nephrol
|
2005
|
0.90
|
|
51
|
Accumulation of tissue advanced glycation end products correlated with glucose exposure dose and associated with cardiovascular morbidity in patients on peritoneal dialysis.
|
Atherosclerosis
|
2012
|
0.89
|
|
52
|
Glyoxalase I retards renal senescence.
|
Am J Pathol
|
2011
|
0.89
|
|
53
|
Current issues and future perspectives of chronic renal failure.
|
J Am Soc Nephrol
|
2002
|
0.88
|
|
54
|
Metabolic stress response implicated in diabetic retinopathy: the role of calpain, and the therapeutic impact of calpain inhibitor.
|
Neurobiol Dis
|
2012
|
0.88
|
|
55
|
Advanced glycation end products, carotid atherosclerosis, and circulating endothelial progenitor cells in patients with end-stage renal disease.
|
Metabolism
|
2010
|
0.88
|
|
56
|
Skin advanced glycation end product accumulation and muscle strength among adult men.
|
Eur J Appl Physiol
|
2010
|
0.88
|
|
57
|
Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes.
|
Diabetologia
|
2013
|
0.88
|
|
58
|
Relationship of skin autofluorescence to cardiovascular disease in Japanese hemodialysis patients.
|
Ther Apher Dial
|
2010
|
0.87
|
|
59
|
Advanced glycation end products in patients with cerebral infarction.
|
Intern Med
|
2009
|
0.87
|
|
60
|
Redox-linked cell surface-oriented signaling for T-cell death.
|
Antioxid Redox Signal
|
2002
|
0.85
|
|
61
|
Lower serum endogenous secretory receptor for advanced glycation end product level as a risk factor of metabolic syndrome among Japanese adult men: a 2-year longitudinal study.
|
J Clin Endocrinol Metab
|
2013
|
0.85
|
|
62
|
Keap1 inhibition attenuates glomerulosclerosis.
|
Nephrol Dial Transplant
|
2014
|
0.85
|
|
63
|
Advanced glycation end-products, anti-hypertensive treatment and diastolic function in patients with hypertension and diastolic dysfunction.
|
Eur J Heart Fail
|
2010
|
0.83
|
|
64
|
Protection of endothelial cells by dextran sulfate in rats with thrombotic microangiopathy.
|
J Am Soc Nephrol
|
2005
|
0.83
|
|
65
|
Mesangial cell-predominant functional gene, megsin.
|
Clin Exp Nephrol
|
2003
|
0.83
|
|
66
|
Albumin suppresses vascular endothelial growth factor via alteration of hypoxia-inducible factor/hypoxia-responsive element pathway.
|
Biochem Biophys Res Commun
|
2007
|
0.83
|
|
67
|
A novel class of advanced glycation inhibitors ameliorates renal and cardiovascular damage in experimental rat models.
|
Nephrol Dial Transplant
|
2007
|
0.83
|
|
68
|
Inhibition of plasminogen activator inhibitor-1 is a potential therapeutic strategy in ovarian cancer.
|
Cancer Biol Ther
|
2015
|
0.83
|
|
69
|
Glucose dialysate induces mitochondrial DNA damage in peritoneal mesothelial cells.
|
Perit Dial Int
|
2002
|
0.83
|
|
70
|
Receptor-independent intracellular radical scavenging activity of an angiotensin II receptor blocker.
|
J Hypertens
|
2007
|
0.81
|
|
71
|
Idiopathic carbonyl stress in a drug-naive case of at-risk mental state.
|
Psychiatry Clin Neurosci
|
2011
|
0.81
|
|
72
|
The role of megsin, a serine protease inhibitor, in diabetic mesangial matrix accumulation.
|
Kidney Int
|
2008
|
0.81
|
|
73
|
Very high doses of valsartan provide renoprotection independently of blood pressure in a type 2 diabetic nephropathy rat model.
|
Nephrology (Carlton)
|
2009
|
0.81
|
|
74
|
High plasma pentosidine level is accompanied with cardiovascular events in hemodialysis patients.
|
Clin Exp Nephrol
|
2011
|
0.81
|
|
75
|
Body weight control by a high-carbohydrate/low-fat diet slows the progression of diabetic kidney damage in an obese, hypertensive, type 2 diabetic rat model.
|
J Obes
|
2010
|
0.80
|
|
76
|
Advanced glycation end products in uremia.
|
Adv Ren Replace Ther
|
2003
|
0.80
|
|
77
|
Renoprotection of angiotensin receptor blockers: beyond blood pressure lowering.
|
Nephrol Dial Transplant
|
2006
|
0.80
|
|
78
|
A novel inhibitor of advanced glycation and endoplasmic reticulum stress reduces infarct volume in rat focal cerebral ischemia.
|
Brain Res
|
2007
|
0.80
|
|
79
|
Blockade of angiotensin II type-1 receptor increases salt sensitivity in Sprague-Dawley rats.
|
Hypertens Res
|
2009
|
0.79
|
|
80
|
Mild oxidative damage in the diabetic rat heart is attenuated by glyoxalase-1 overexpression.
|
Int J Mol Sci
|
2013
|
0.79
|
|
81
|
A novel Sartan derivative with very low angiotensin II type 1 receptor affinity protects the kidney in type 2 diabetic rats.
|
Arterioscler Thromb Vasc Biol
|
2008
|
0.79
|
|
82
|
Angiotensin-induced hypoxia in the kidney: functional and structural changes of the renal circulation.
|
Adv Exp Med Biol
|
2007
|
0.79
|
|
83
|
Skin autofluorescence predicts cardiovascular mortality in patients on chronic hemodialysis.
|
Ther Apher Dial
|
2014
|
0.78
|
|
84
|
Ultrapure dialysate decreases plasma pentosidine, a marker of "carbonyl stress".
|
Am J Kidney Dis
|
2004
|
0.78
|
|
85
|
Involvement of MEKK1/ERK/P21Waf1/Cip1 signal transduction pathway in inhibition of IGF-I-mediated cell growth response by methylglyoxal.
|
J Cell Biochem
|
2003
|
0.78
|
|
86
|
Transcriptional regulation of a mesangium-predominant gene, megsin.
|
J Am Soc Nephrol
|
2002
|
0.78
|
|
87
|
Structure-activity relationships of new N-acylanthranilic acid derivatives as plasminogen activator inhibitor-1 inhibitors.
|
Chem Pharm Bull (Tokyo)
|
2011
|
0.78
|
|
88
|
Role of chronic hypoxia and hypoxia inducible factor in kidney disease.
|
Chin Med J (Engl)
|
2008
|
0.78
|
|
89
|
Mesangial cell-predominant gene, megsin.
|
Nephrol Dial Transplant
|
2002
|
0.78
|
|
90
|
Pyridoxamine improves functional, structural, and biochemical alterations of peritoneal membranes in uremic peritoneal dialysis rats.
|
Kidney Int
|
2005
|
0.78
|
|
91
|
Higher serum soluble receptor for advanced glycation end product levels and lower prevalence of metabolic syndrome among Japanese adult men: a cross-sectional study.
|
Diabetol Metab Syndr
|
2014
|
0.78
|
|
92
|
Low parathyroid hormone and pentosidine in hemodialysis patients.
|
Am J Kidney Dis
|
2002
|
0.78
|
|
93
|
Neovascularization induced by hypoxia inducible transcription factor is associated with the improvement of cardiac dysfunction in experimental autoimmune myocarditis.
|
Expert Opin Investig Drugs
|
2013
|
0.78
|
|
94
|
A rat model of human FENIB (familial encephalopathy with neuroserpin inclusion bodies).
|
Biochem Biophys Res Commun
|
2006
|
0.78
|
|
95
|
Reduction of albuminuria by angiotensin receptor blocker beyond blood pressure lowering: evaluation in megsin/receptor for advanced glycation end products/inducible nitric oxide synthase triple transgenic diabetic nephropathy mouse model.
|
Nephrology (Carlton)
|
2008
|
0.77
|
|
96
|
Delayed cutaneous wound healing in Fam129b/Minerva-deficient mice.
|
J Biochem
|
2012
|
0.77
|
|
97
|
A sartan derivative with a very low angiotensin II receptor affinity ameliorates ischemic cerebral damage.
|
J Cereb Blood Flow Metab
|
2009
|
0.77
|
|
98
|
ET(B) receptor protects the tubulointerstitium in experimental thrombotic microangiopathy.
|
Kidney Int
|
2002
|
0.77
|
|
99
|
Establishment of a sandwich ELISA for human megsin, a kidney-specific serine protease inhibitor.
|
Nephrol Dial Transplant
|
2007
|
0.77
|
|
100
|
Translation of basic science into clinical medicine: novel targets for diabetic nephropathy.
|
Nephrol Dial Transplant
|
2009
|
0.77
|
|
101
|
TM5275 prolongs secreted tissue plasminogen activator retention and enhances fibrinolysis on vascular endothelial cells.
|
Thromb Res
|
2013
|
0.77
|
|
102
|
Successful repair for isolated cleft mitral valve diagnosed by three-dimensional transesophageal echocardiography.
|
J Heart Valve Dis
|
2012
|
0.77
|
|
103
|
Renal proximal tubular metabolism of protein-linked pentosidine, an advanced glycation end product.
|
Nephron
|
2002
|
0.76
|
|
104
|
Relationship of skin autofluorescence to severity of retinopathy in type 2 diabetes.
|
Curr Eye Res
|
2014
|
0.76
|
|
105
|
Inhibition of plasminogen activator inhibitor type-1 activity enhances rapid and sustainable hematopoietic regeneration.
|
Stem Cells
|
2014
|
0.76
|
|
106
|
Structure-activity relationships of new 2-acylamino-3-thiophenecarboxylic acid dimers as plasminogen activator inhibitor-1 inhibitors.
|
Chem Pharm Bull (Tokyo)
|
2010
|
0.76
|
|
107
|
Angiotensin II type 1A receptor deficiency and longevity.
|
Nephrol Dial Transplant
|
2009
|
0.76
|
|
108
|
Advanced glycation and advanced oxidation protein products: the effect of peritoneal dialysis.
|
Perit Dial Int
|
2006
|
0.75
|
|
109
|
A novel prolyl hydroxylase inhibitor protects against cell death after hypoxia.
|
Neurochem Res
|
2013
|
0.75
|
|
110
|
A novel clinical biomarker for myeloperoxidase-antineutrophil cytoplasmic antibody associated glomerulonephritis.
|
Clin Exp Pharmacol Physiol
|
2010
|
0.75
|
|
111
|
[Carbonyl stress inhibitor towards new therapeutic interventions in diabetic nephropathy].
|
Nihon Rinsho
|
2004
|
0.75
|
|
112
|
Carbonyl stress reduction in peritoneal dialysis fluid: development of a novel high-affinity adsorption bead.
|
Perit Dial Int
|
2007
|
0.75
|
|
113
|
Hypoxia-sensitive reporter system for high-throughput screening.
|
Tohoku J Exp Med
|
2015
|
0.75
|
|
114
|
[Molecular pathophysiology of schizophrenia and preventive strategy in pubertal period].
|
Seishin Shinkeigaku Zasshi
|
2011
|
0.75
|
|
115
|
Synergistic contributions of carbonyl stress and megsin in diabetic nephropathy.
|
Ann N Y Acad Sci
|
2005
|
0.75
|
|
116
|
[Translational research of novel PAI-1 inhibitors].
|
Nihon Yakurigaku Zasshi
|
2010
|
0.75
|
|
117
|
[Mechanisms in remodeling of the kidney].
|
Nihon Rinsho
|
2008
|
0.75
|
|
118
|
Effect of edaravone on the estimated glomerular filtration rate in patients with acute ischemic stroke and chronic kidney disease.
|
J Stroke Cerebrovasc Dis
|
2010
|
0.75
|
|
119
|
[Novel therapeutic approaches to diabetic nephropathy].
|
Nihon Jinzo Gakkai Shi
|
2007
|
0.75
|
|
120
|
Affinity adsorption of glucose degradation products improves the biocompatibility of conventional peritoneal dialysis fluid.
|
Kidney Int
|
2003
|
0.75
|
|
121
|
Plasminogen activator inhibitor-1 (PAI-1) molecule: new physiological roles and clinical applications.
|
Rinsho Ketsueki
|
2014
|
0.75
|
|
122
|
Accelerated glomerular injury in hemi-nephrectomized transgenic mice of mesangial cell-predominant serpin, megsin.
|
Nephron Exp Nephrol
|
2004
|
0.75
|
|
123
|
[New perspective for drug discovery and clinical development in kidney disease].
|
Nihon Jinzo Gakkai Shi
|
2012
|
0.75
|
|
124
|
[Post-genome research on megsin, a kidney-specific serpin gene].
|
Nihon Rinsho
|
2006
|
0.75
|
|
125
|
Replication of enhanced carbonyl stress in a subpopulation of schizophrenia.
|
Psychiatry Clin Neurosci
|
2013
|
0.75
|
|
126
|
Proteomics and mesangial cell: serpin, megsin and plasmin.
|
Contrib Nephrol
|
2004
|
0.75
|
|
127
|
Role of specific T-type calcium channel blocker R(-) efonidipine in the regulation of renal medullary circulation.
|
J Hypertens
|
2012
|
0.75
|