Published in Arthritis Rheum on June 01, 2002
Aggrecanases and cartilage matrix degradation. Arthritis Res Ther (2003) 1.97
The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis. Arthritis Res Ther (2006) 1.93
Osteoarthritis and nutrition. From nutraceuticals to functional foods: a systematic review of the scientific evidence. Arthritis Res Ther (2006) 1.53
Self-correction in biomedical publications and the scientific impact. Croat Med J (2014) 1.44
Pathogenesis of degenerative temporomandibular joint arthritides. Odontology (2005) 1.16
The role of ADAMTSs in arthritis. Protein Cell (2010) 1.03
Natural anti-inflammatory agents for pain relief. Surg Neurol Int (2010) 0.97
Omega-3 fatty acid supplementation decreases matrix metalloproteinase-9 production in relapsing-remitting multiple sclerosis. Prostaglandins Leukot Essent Fatty Acids (2009) 0.96
Effects of Glucosamine and Chondroitin Sulfate on Cartilage Metabolism in OA: Outlook on Other Nutrient Partners Especially Omega-3 Fatty Acids. Int J Rheumatol (2011) 0.95
The Effect of Omega-3 Fatty Acid Supplementation on the Inflammatory Response to eccentric strength exercise. J Sports Sci Med (2011) 0.91
Scientific evidence and rationale for the development of curcumin and resveratrol as nutraceutricals for joint health. Int J Mol Sci (2012) 0.90
Nutraceuticals: potential for chondroprotection and molecular targeting of osteoarthritis. Int J Mol Sci (2013) 0.88
Dietary fatty acid intake affects the risk of developing bone marrow lesions in healthy middle-aged adults without clinical knee osteoarthritis: a prospective cohort study. Arthritis Res Ther (2009) 0.88
A longitudinal study of the association between dietary factors, serum lipids, and bone marrow lesions of the knee. Arthritis Res Ther (2012) 0.86
Advances in nutritional research on regulatory T-cells. Nutrients (2013) 0.76
Dietary Lipid During Late-Pregnancy and Early-Lactation to Manipulate Metabolic and Inflammatory Gene Network Expression in Dairy Cattle Liver with a Focus on PPARs. Gene Regul Syst Bio (2013) 0.76
Deficiency of G-protein coupled receptor 40, a lipid-activated receptor, heightens in vitro- and in vivo-induced murine osteoarthritis. Exp Biol Med (Maywood) (2015) 0.75
Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis. Nature (2005) 5.71
Lipids and lipid metabolism in eukaryotic algae. Prog Lipid Res (2006) 2.62
Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice. Arthritis Rheum (2004) 2.01
The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis. Arthritis Res Ther (2006) 1.93
The role of human HtrA1 in arthritic disease. J Biol Chem (2005) 1.91
Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing. J Biol Chem (2003) 1.87
Pharmacological brake-release of mRNA translation enhances cognitive memory. Elife (2013) 1.85
Proteolytic activities of human ADAMTS-5: comparative studies with ADAMTS-4. J Biol Chem (2007) 1.66
The role of synovial macrophages and macrophage-produced mediators in driving inflammatory and destructive responses in osteoarthritis. Arthritis Rheum (2010) 1.63
Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254). Arthritis Res Ther (2010) 1.61
Proteoglycan 4 downregulation in a sheep meniscectomy model of early osteoarthritis. Arthritis Res Ther (2006) 1.55
Comparative proteomic characterization of articular cartilage tissue from normal donors and patients with osteoarthritis. Arthritis Rheum (2007) 1.48
Can the stress protein response be controlled by 'membrane-lipid therapy'? Trends Biochem Sci (2007) 1.47
Binding and localization of recombinant lubricin to articular cartilage surfaces. J Orthop Res (2007) 1.34
Immunolocalisation and expression of proteoglycan 4 (cartilage superficial zone proteoglycan) in tendon. Matrix Biol (2002) 1.32
Increasing the flow of carbon into seed oil. Biotechnol Adv (2009) 1.31
Fertility below replacement level. Science (2004) 1.27
The significance of lipid composition for membrane activity: new concepts and ways of assessing function. Prog Lipid Res (2005) 1.25
ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage. Matrix Biol (2004) 1.24
Chondroitin sulfate sulfation motifs as putative biomarkers for isolation of articular cartilage progenitor cells. J Histochem Cytochem (2007) 1.22
Low frequency EMF regulates chondrocyte differentiation and expression of matrix proteins. J Orthop Res (2002) 1.22
Identification of a novel HtrA1-susceptible cleavage site in human aggrecan: evidence for the involvement of HtrA1 in aggrecan proteolysis in vivo. J Biol Chem (2009) 1.17
Macromolecular organization and in vitro growth characteristics of scaffold-free neocartilage grafts. J Histochem Cytochem (2007) 1.15
Matrix metalloproteinases are involved in C-terminal and interglobular domain processing of cartilage aggrecan in late stage cartilage degradation. Matrix Biol (2002) 1.14
Metabolic control analysis is helpful for informed genetic manipulation of oilseed rape (Brassica napus) to increase seed oil content. J Exp Bot (2008) 1.13
A raison d'être for two distinct pathways in the early steps of plant isoprenoid biosynthesis? Prog Lipid Res (2011) 1.11
Fragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared with age-matched macroscopically normal and control tissues. Arthritis Res Ther (2008) 1.09
Mechanisms of temperature adaptation in poikilotherms. FEBS Lett (2006) 1.09
TIMP-3 inhibits aggrecanase-mediated glycosaminoglycan release from cartilage explants stimulated by catabolic factors. FEBS Lett (2003) 1.08
Modulation of lubricin biosynthesis and tissue surface properties following cartilage mechanical injury. Arthritis Rheum (2009) 1.08
Human intervertebral disc aggrecan inhibits nerve growth in vitro. Arthritis Rheum (2002) 1.07
Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: comparative analyses with ADAMTS-5, -9, -16 and -18. Biochim Biophys Acta (2006) 1.06
Lipidomics reveals membrane lipid remodelling and release of potential lipid mediators during early stress responses in a murine melanoma cell line. Biochim Biophys Acta (2010) 1.04
Boundary mode lubrication of articular cartilage by recombinant human lubricin. J Orthop Res (2009) 1.04
Heat shock response in photosynthetic organisms: membrane and lipid connections. Prog Lipid Res (2012) 1.04
Membrane regulation of the stress response from prokaryotic models to mammalian cells. Ann N Y Acad Sci (2007) 1.03
Matrix morphogenesis in cornea is mediated by the modification of keratan sulfate by GlcNAc 6-O-sulfotransferase. Proc Natl Acad Sci U S A (2006) 1.02
Release of hyaluronan and hyaladherins (aggrecan G1 domain and link proteins) from articular cartilage exposed to ADAMTS-4 (aggrecanase 1) or ADAMTS-5 (aggrecanase 2). Arthritis Rheum (2004) 1.00
Differential immunogold localisation of sulphated and unsulphated keratan sulphate proteoglycans in normal and macular dystrophy cornea using sulphation motif-specific antibodies. Histochem Cell Biol (2006) 1.00
Human intervertebral disc aggrecan inhibits endothelial cell adhesion and cell migration in vitro. Spine (Phila Pa 1976) (2005) 0.99
Low molecular weight isoforms of the aggrecanases are responsible for the cytokine-induced proteolysis of aggrecan in a porcine chondrocyte culture system. Arthritis Rheum (2007) 0.98
Interferon-gamma protects against the development of structural damage in experimental arthritis by regulating polymorphonuclear neutrophil influx into diseased joints. Arthritis Rheum (2007) 0.98
A bifunctional Delta12,Delta15-desaturase from Acanthamoeba castellanii directs the synthesis of highly unusual n-1 series unsaturated fatty acids. J Biol Chem (2006) 0.98
Biochemical composition and turnover of the extracellular matrix of the normal and degenerate intervertebral disc. Eur Spine J (2013) 0.98
Use of anti-neoepitope antibodies for the analysis of degradative events in cartilage and the molecular basis for neoepitope specificity. Biochem Soc Symp (2003) 0.97
Analogues of thiolactomycin as potential antimalarial agents. J Med Chem (2005) 0.97
The potential of IGF-1 and TGFbeta1 for promoting "adult" articular cartilage repair: an in vitro study. Tissue Eng Part A (2008) 0.97
Advances in measuring lifespan in the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2004) 0.96
Heat stress causes spatially-distinct membrane re-modelling in K562 leukemia cells. PLoS One (2011) 0.96
Retracted Effects of n-3 fatty acids on cartilage metabolism. Proc Nutr Soc (2002) 0.93
Complement C3c and related protein biomarkers in amyotrophic lateral sclerosis and Parkinson's disease. Biochem Biophys Res Commun (2006) 0.93
Serine protease HTRA1 antagonizes transforming growth factor-β signaling by cleaving its receptors and loss of HTRA1 in vivo enhances bone formation. PLoS One (2013) 0.92
LXR modulation blocks prostaglandin E2 production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model. Proc Natl Acad Sci U S A (2010) 0.91
Neuroscience. Freeing the bain from the perineuronal net. Science (2002) 0.91
Tenascin-C induces inflammatory mediators and matrix degradation in osteoarthritic cartilage. BMC Musculoskelet Disord (2011) 0.91
Control analysis of lipid biosynthesis in tissue cultures from oil crops shows that flux control is shared between fatty acid synthesis and lipid assembly. Biochem J (2002) 0.91
Eicosapentaenoic acid and docosahexaenoic acid regulate modified LDL uptake and macropinocytosis in human macrophages. Lipids (2011) 0.90
N-((8-hydroxy-5-substituted-quinolin-7-yl)(phenyl)methyl)-2-phenyloxy/amino-acetamide inhibitors of ADAMTS-5 (Aggrecanase-2). Bioorg Med Chem Lett (2008) 0.89
Glycolytic breakdown of sulfoquinovose in bacteria: a missing link in the sulfur cycle. Appl Environ Microbiol (2003) 0.89
Graminicide insensitivity correlates with herbicide-binding co-operativity on acetyl-CoA carboxylase isoforms. Biochem J (2003) 0.88
Catabolic responses of chondrocyte-seeded peptide hydrogel to dynamic compression. Ann Biomed Eng (2009) 0.88
Key role of lipids in heat stress management. FEBS Lett (2013) 0.88
Keratan sulfate glycosaminoglycan and the association with collagen fibrils in rudimentary lamellae in the developing avian cornea. Invest Ophthalmol Vis Sci (2007) 0.87
Differential expression of the keratan sulphate proteoglycan, keratocan, during chick corneal embryogenesis. Histochem Cell Biol (2007) 0.87
Spinal position sense and trunk muscle activity during sitting and standing in nonspecific chronic low back pain: classification analysis. Spine (Phila Pa 1976) (2012) 0.87
A comparative evaluation of the small leucine-rich proteoglycans of pathological human intervertebral discs. Eur Spine J (2012) 0.87
Pyran-containing sulfonamide hydroxamic acids: potent MMP inhibitors that spare MMP-1. Bioorg Med Chem Lett (2004) 0.86
Sulfation of the bikunin chondroitin sulfate chain determines heavy chain·hyaluronan complex formation. J Biol Chem (2013) 0.86
Analogues of thiolactomycin as potential anti-malarial and anti-trypanosomal agents. Bioorg Med Chem (2004) 0.86
Ultrastructural localization and distribution of proteoglycan in normal and scoliotic lumbar disc. Spine (Phila Pa 1976) (2005) 0.85
Assessment of specific mRNA levels in cartilage regions in a lapine model of osteoarthritis. J Orthop Res (2002) 0.85
Atypical composition and ultrastructure of proteoglycans in the mouse corneal stroma. Invest Ophthalmol Vis Sci (2005) 0.85
Extraordinary shifts of the Leidenfrost temperature from multiscale micro/nanostructured surfaces. Langmuir (2013) 0.85
Lead and copper effects on lipid metabolism in cultured lichen photobionts with different phosphorus status. Phytochemistry (2006) 0.85
5-((1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one inhibitors of ADAMTS-5. Bioorg Med Chem Lett (2006) 0.85
Antibodies and immunohistochemistry in extracellular matrix research. Methods (2008) 0.85
Ultrastructural immunolocalization of alpha-elastin and keratan sulfate proteoglycan in normal and scoliotic lumbar disc. Spine (Phila Pa 1976) (2005) 0.85
Disposition of human recombinant lubricin in naive rats and in a rat model of post-traumatic arthritis after intra-articular or intravenous administration. AAPS J (2012) 0.85
The relationship between plasma and red cell concentrations of vitamins thiamine diphosphate, flavin adenine dinucleotide and pyridoxal 5-phosphate following elective knee arthroplasty. Clin Nutr (2004) 0.84