PubRank

James E Pease

Author PubWeight™ 34.88‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A single nucleotide polymorphism in the CCR3 gene ablates receptor export to the plasma membrane. J Allergy Clin Immunol 2010 1.42
2 The chemokine receptor CXCR3 is degraded following internalization and is replenished at the cell surface by de novo synthesis of receptor. J Immunol 2008 1.28
3 Predictions of CCR1 chemokine receptor structure and BX 471 antagonist binding followed by experimental validation. J Biol Chem 2006 1.24
4 CXCL4-induced migration of activated T lymphocytes is mediated by the chemokine receptor CXCR3. J Leukoc Biol 2008 1.16
5 Molecular characterization of the chemokine receptor CXCR3: evidence for the involvement of distinct extracellular domains in a multi-step model of ligand binding and receptor activation. Eur J Immunol 2003 1.13
6 The CXC chemokine MIG/CXCL9 is important in innate immunity against Streptococcus pyogenes. J Infect Dis 2007 1.08
7 Chemokine and cytokine mediated loss of regulatory T cells in lymph nodes during pathogenic simian immunodeficiency virus infection. J Immunol 2008 1.06
8 A distinct subset of human NK cells expressing HLA-DR expand in response to IL-2 and can aid immune responses to BCG. Eur J Immunol 2011 1.04
9 Contrary prostaglandins: the opposing roles of PGD2 and its metabolites in leukocyte function. J Leukoc Biol 2006 1.04
10 Structure and function of A41, a vaccinia virus chemokine binding protein. PLoS Pathog 2008 1.04
11 Small molecule receptor agonists and antagonists of CCR3 provide insight into mechanisms of chemokine receptor activation. J Biol Chem 2007 1.00
12 Small molecule chemokine mimetics suggest a molecular basis for the observation that CXCL10 and CXCL11 are allosteric ligands of CXCR3. Br J Pharmacol 2012 0.99
13 Noncompetitive antagonism and inverse agonism as mechanism of action of nonpeptidergic antagonists at primate and rodent CXCR3 chemokine receptors. J Pharmacol Exp Ther 2008 0.99
14 Structure/function relationships of CCR8 agonists and antagonists. Amino-terminal extension of CCL1 by a single amino acid generates a partial agonist. J Biol Chem 2006 0.99
15 CCR4 in human allergen-induced late responses in the skin and lung. Eur J Immunol 2002 0.99
16 CCR4 blockade does not inhibit allergic airways inflammation. J Leukoc Biol 2003 0.97
17 Alanine scanning mutagenesis of CCR3 reveals that the three intracellular loops are essential for functional receptor expression. Eur J Immunol 2002 0.95
18 Site-directed mutagenesis of CC chemokine receptor 1 reveals the mechanism of action of UCB 35625, a small molecule chemokine receptor antagonist. J Biol Chem 2004 0.95
19 The role of the CCL2/CCR2 axis in mouse mast cell migration in vitro and in vivo. J Immunol 2010 0.94
20 Human T(H)2 cells respond to cysteinyl leukotrienes through selective expression of cysteinyl leukotriene receptor 1. J Allergy Clin Immunol 2012 0.94
21 11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils. J Biol Chem 2003 0.93
22 Variations in eosinophil chemokine responses: an investigation of CCR1 and CCR3 function, expression in atopy, and identification of a functional CCR1 promoter. J Immunol 2003 0.90
23 Stretch and inflammatory cytokines drive myometrial chemokine expression via NF-κB activation. Endocrinology 2011 0.89
24 Elucidation of binding sites of dual antagonists in the human chemokine receptors CCR2 and CCR5. Mol Pharmacol 2009 0.89
25 Alanine scanning mutagenesis of the chemokine receptor CCR3 reveals distinct extracellular residues involved in recognition of the eotaxin family of chemokines. Mol Immunol 2005 0.88
26 Proteoglycans are potent modulators of the biological responses of eosinophils to chemokines. Eur J Immunol 2003 0.85
27 Modeling small molecule-compound binding to G-protein-coupled receptors. Methods Enzymol 2009 0.85
28 CCL17/thymus and activation-regulated chemokine induces calcitonin gene-related peptide in human airway epithelial cells through CCR4. J Allergy Clin Immunol 2013 0.85
29 Editorial: are all eotaxins created equal? J Leukoc Biol 2013 0.84
30 The carboxyl terminus of the chemokine receptor CCR3 contains distinct domains which regulate chemotactic signaling and receptor down-regulation in a ligand-dependent manner. Eur J Immunol 2005 0.83
31 Distinct conformations of the chemokine receptor CCR4 with implications for its targeting in allergy. J Immunol 2014 0.83
32 The identification, characterization, and distribution of guinea pig CCR4 and epitope mapping of a blocking antibody. J Biol Chem 2001 0.82
33 Site-directed mutagenesis of the chemokine receptor CXCR6 suggests a novel paradigm for interactions with the ligand CXCL16. Eur J Immunol 2008 0.79
34 Human labour is associated with a decline in myometrial chemokine receptor expression: the role of prostaglandins, oxytocin and cytokines. Am J Reprod Immunol 2012 0.76
35 CXCR3 antagonist VUF10085 binds to an intrahelical site distinct from that of the broad spectrum antagonist TAK-779. Br J Pharmacol 2015 0.76
36 The CXCL16 A181V mutation selectively inhibits monocyte adhesion to CXCR6 but is not associated with human coronary heart disease. Arterioscler Thromb Vasc Biol 2011 0.76
37 The use of membrane translocating peptides to identify sites of interaction between the C5a receptor and downstream effector proteins. Immunology 2004 0.76