Timothy J Williams

Author PubWeight™ 51.45‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The genomic basis of trophic strategy in marine bacteria. Proc Natl Acad Sci U S A 2009 3.72
2 Chemokines acting via CXCR2 and CXCR4 control the release of neutrophils from the bone marrow and their return following senescence. Immunity 2003 3.55
3 A single nucleotide polymorphism in the CCR3 gene ablates receptor export to the plasma membrane. J Allergy Clin Immunol 2010 1.42
4 The genome sequence of the psychrophilic archaeon, Methanococcoides burtonii: the role of genome evolution in cold adaptation. ISME J 2009 1.40
5 Eotaxin (CCL11) and eotaxin-2 (CCL24) induce recruitment of eosinophils, basophils, neutrophils, and macrophages as well as features of early- and late-phase allergic reactions following cutaneous injection in human atopic and nonatopic volunteers. J Immunol 2002 1.35
6 Complete genome sequence of the chemolithoautotrophic marine magnetotactic coccus strain MC-1. Appl Environ Microbiol 2009 1.34
7 The chemokine receptor CXCR3 is degraded following internalization and is replenished at the cell surface by de novo synthesis of receptor. J Immunol 2008 1.28
8 Magnetovibrio blakemorei gen. nov., sp. nov., a magnetotactic bacterium (Alphaproteobacteria: Rhodospirillaceae) isolated from a salt marsh. Int J Syst Evol Microbiol 2012 1.24
9 Leukotriene B4, an activation product of mast cells, is a chemoattractant for their progenitors. J Exp Med 2005 1.23
10 Metaproteogenomic analysis of a dominant green sulfur bacterium from Ace Lake, Antarctica. ISME J 2010 1.17
11 CXCL4-induced migration of activated T lymphocytes is mediated by the chemokine receptor CXCR3. J Leukoc Biol 2008 1.16
12 The attraction of chemokines as a target for specific anti-inflammatory therapy. Br J Pharmacol 2006 1.16
13 Chemotactic action of prostaglandin E2 on mouse mast cells acting via the PGE2 receptor 3. Proc Natl Acad Sci U S A 2007 1.16
14 High level of intergenera gene exchange shapes the evolution of haloarchaea in an isolated Antarctic lake. Proc Natl Acad Sci U S A 2013 1.16
15 A metagenomic assessment of winter and summer bacterioplankton from Antarctica Peninsula coastal surface waters. ISME J 2012 1.15
16 Histamine induces cytoskeletal changes in human eosinophils via the H(4) receptor. Br J Pharmacol 2003 1.15
17 Molecular characterization of the chemokine receptor CXCR3: evidence for the involvement of distinct extracellular domains in a multi-step model of ligand binding and receptor activation. Eur J Immunol 2003 1.13
18 Cold adaptation in the marine bacterium, Sphingopyxis alaskensis, assessed using quantitative proteomics. Environ Microbiol 2010 1.13
19 Key microbial drivers in Antarctic aquatic environments. FEMS Microbiol Rev 2012 1.09
20 Mechanisms underlying the localisation of mast cells in tissues. Trends Immunol 2011 1.01
21 Small molecule receptor agonists and antagonists of CCR3 provide insight into mechanisms of chemokine receptor activation. J Biol Chem 2007 1.00
22 Magnetococcus marinus gen. nov., sp. nov., a marine, magnetotactic bacterium that represents a novel lineage (Magnetococcaceae fam. nov., Magnetococcales ord. nov.) at the base of the Alphaproteobacteria. Int J Syst Evol Microbiol 2012 0.99
23 CCR4 in human allergen-induced late responses in the skin and lung. Eur J Immunol 2002 0.99
24 Metagenomic insights into strategies of carbon conservation and unusual sulfur biogeochemistry in a hypersaline Antarctic lake. ISME J 2013 0.98
25 CCR4 blockade does not inhibit allergic airways inflammation. J Leukoc Biol 2003 0.97
26 Chemolithoautotrophy in the marine, magnetotactic bacterial strains MV-1 and MV-2. Arch Microbiol 2004 0.96
27 Site-directed mutagenesis of CC chemokine receptor 1 reveals the mechanism of action of UCB 35625, a small molecule chemokine receptor antagonist. J Biol Chem 2004 0.95
28 The role of the CCL2/CCR2 axis in mouse mast cell migration in vitro and in vivo. J Immunol 2010 0.94
29 Plasma concentrations and role of macrophage inflammatory protein-1alpha during chronic Schistosoma mansoni infection in humans. J Infect Dis 2002 0.91
30 Innate and cognate mechanisms of pulmonary eosinophilia in helminth infection. Eur J Immunol 2002 0.91
31 Variations in eosinophil chemokine responses: an investigation of CCR1 and CCR3 function, expression in atopy, and identification of a functional CCR1 promoter. J Immunol 2003 0.90
32 Biogeographic partitioning of Southern Ocean microorganisms revealed by metagenomics. Environ Microbiol 2012 0.89
33 Alanine scanning mutagenesis of the chemokine receptor CCR3 reveals distinct extracellular residues involved in recognition of the eotaxin family of chemokines. Mol Immunol 2005 0.88
34 Influenza virus- and cytokine-immunoreactive cells in the murine olfactory and central autonomic nervous systems before and after illness onset. J Neuroimmunol 2009 0.88
35 Indomethacin causes prostaglandin D(2)-like and eotaxin-like selective responses in eosinophils and basophils. J Biol Chem 2002 0.88
36 Proteoglycans are potent modulators of the biological responses of eosinophils to chemokines. Eur J Immunol 2003 0.85
37 Editorial: are all eotaxins created equal? J Leukoc Biol 2013 0.84
38 The carboxyl terminus of the chemokine receptor CCR3 contains distinct domains which regulate chemotactic signaling and receptor down-regulation in a ligand-dependent manner. Eur J Immunol 2005 0.83
39 The function of CCR3 on mouse bone marrow-derived mast cells in vitro. Immunology 2010 0.82
40 Acute allergic responses induce a prompt luminal entry of airway tissue eosinophils. Am J Respir Cell Mol Biol 2003 0.82
41 The identification, characterization, and distribution of guinea pig CCR4 and epitope mapping of a blocking antibody. J Biol Chem 2001 0.82
42 Responses of leukocytes to chemokines in whole blood and their antagonism by novel CC-chemokine receptor 3 antagonists. Am J Respir Crit Care Med 2002 0.80
43 Identification of selective basophil chemoattractants in human nasal polyps as insulin-like growth factor-1 and insulin-like growth factor-2. J Immunol 2004 0.79
44 Chaperonins from an Antarctic archaeon are predominantly monomeric: crystal structure of an open state monomer. Environ Microbiol 2011 0.77
45 Analyzing the hydrophobic proteome of the antarctic archaeon Methanococcoides burtonii using differential solubility fractionation. J Proteome Res 2010 0.77
46 P-selectin mediates IL-13-induced eosinophil transmigration but not eotaxin generation in vivo: a comparative study with IL-4-elicited responses. J Leukoc Biol 2003 0.76
47 Stalking the chemokine. Am J Respir Crit Care Med 2002 0.75
48 Identification of a 5-HT4 receptor antagonist clinical candidate through side-chain modification. Bioorg Med Chem Lett 2005 0.75
49 The RNA polymerase subunits E/F from the Antarctic archaeon Methanococcoides burtonii bind to specific species of mRNA. Environ Microbiol 2010 0.75