Published in J Neurosci Res on August 01, 2002
Glutathione dysregulation and the etiology and progression of human diseases. Biol Chem (2009) 2.70
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Flavonoid-induced glutathione depletion: potential implications for cancer treatment. Free Radic Biol Med (2006) 1.07
4-Hydroxynonenal, a product of oxidative stress, leads to an antioxidant response in optic nerve head astrocytes. Exp Eye Res (2006) 1.03
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Enhanced glutathione efflux from astrocytes in culture by low extracellular Ca2+ and curcumin. Neurochem Res (2010) 0.81
Role of a redox-based methylation switch in mRNA life cycle (pre- and post-transcriptional maturation) and protein turnover: implications in neurological disorders. Front Neurosci (2012) 0.80
Role of multidrug transporters in neurotherapeutics. Ann Indian Acad Neurol (2009) 0.80
Volume-sensitive anion channels mediate osmosensitive glutathione release from rat thymocytes. PLoS One (2013) 0.79
Magnolol Protects against MPTP/MPP(+)-Induced Toxicity via Inhibition of Oxidative Stress in In Vivo and In Vitro Models of Parkinson's Disease. Parkinsons Dis (2012) 0.79
Interleukin-1β protects astrocytes against oxidant-induced injury via an NF-κB-dependent upregulation of glutathione synthesis. Glia (2015) 0.78
Neuroprotective effects of urate are mediated by augmenting astrocytic glutathione synthesis and release. Neurobiol Dis (2015) 0.78
Adaptive regulation of the brain's antioxidant defences by neurons and astrocytes. Free Radic Biol Med (2016) 0.77
Astrocytes Prevent Ethanol Induced Apoptosis of Nrf2 Depleted Neurons by Maintaining GSH Homeostasis. Open J Apoptosis (2012) 0.75
Nrf2 signaling increases expression of ATP-binding cassette subfamily C mRNA transcripts at the blood-brain barrier following hypoxia-reoxygenation stress. Fluids Barriers CNS (2017) 0.75
l-Theanine protects against excess dopamine-induced neurotoxicity in the presence of astrocytes. J Clin Biochem Nutr (2016) 0.75
PML in a patient treated with fumaric acid. N Engl J Med (2013) 3.87
Colorimetric ferrozine-based assay for the quantitation of iron in cultured cells. Anal Biochem (2004) 2.75
Senataxin, the ortholog of a yeast RNA helicase, is mutant in ataxia-ocular apraxia 2. Nat Genet (2004) 2.75
Early outcome of carotid angioplasty and stenting with and without cerebral protection devices: a systematic review of the literature. Stroke (2003) 2.63
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6. EMBO J (2009) 2.37
Repetitive bilateral arm training and motor cortex activation in chronic stroke: a randomized controlled trial. JAMA (2004) 2.36
Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease. Hum Mol Genet (2005) 2.28
Biological and clinical characteristics of individuals at risk for spinocerebellar ataxia types 1, 2, 3, and 6 in the longitudinal RISCA study: analysis of baseline data. Lancet Neurol (2013) 2.24
Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice. Mol Cell Biol (2004) 2.15
Pre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease models. EMBO J (2009) 2.09
Systematic review of early recurrent stenosis after carotid angioplasty and stenting. Stroke (2004) 2.04
Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily. J Clin Invest (2004) 1.92
Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells. J Exp Med (2011) 1.81
Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial. Ann Neurol (2002) 1.79
Cellular pathology of Parkinson's disease: astrocytes, microglia and inflammation. Cell Tissue Res (2004) 1.76
Short and long-term motor skill learning in an accelerated rotarod training paradigm. Neurobiol Learn Mem (2004) 1.72
Neuroprotection by hypoxic preconditioning requires sequential activation of vascular endothelial growth factor receptor and Akt. J Neurosci (2002) 1.72
Efficient inhibition of the Alzheimer's disease beta-secretase by membrane targeting. Science (2008) 1.67
Transgenic rat model of Huntington's disease. Hum Mol Genet (2003) 1.66
Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation. J Neurochem (2004) 1.61
TDP-43-mediated neuron loss in vivo requires RNA-binding activity. PLoS One (2010) 1.58
Clinical predictors of transient ischemic attack, stroke, or death within 30 days of carotid angioplasty and stenting. Stroke (2005) 1.53
The heart in Friedreich ataxia: definition of cardiomyopathy, disease severity, and correlation with neurological symptoms. Circulation (2012) 1.50
Deep brain stimulation. Cell Tissue Res (2004) 1.42
Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease. Proc Natl Acad Sci U S A (2007) 1.41
Penguins and hummingbirds: midbrain atrophy in progressive supranuclear palsy. Neurology (2006) 1.40
Motor skill learning depends on protein synthesis in motor cortex after training. J Neurosci (2004) 1.37
Progressive degeneration of human mesencephalic neuron-derived cells triggered by dopamine-dependent oxidative stress is dependent on the mixed-lineage kinase pathway. J Neurosci (2005) 1.31
Mitochondrial protein quality control by the proteasome involves ubiquitination and the protease Omi. J Biol Chem (2008) 1.30
The multidrug resistance protein 1 (Mrp1), but not Mrp5, mediates export of glutathione and glutathione disulfide from brain astrocytes. J Neurochem (2006) 1.28
Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease. J Neurosci (2008) 1.28
Identification of CD70-mediated apoptosis of immune effector cells as a novel immune escape pathway of human glioblastoma. Cancer Res (2002) 1.23
Novel homozygous p.E64D mutation in DJ1 in early onset Parkinson disease (PARK7). Hum Mutat (2004) 1.22
Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease. Hum Mol Genet (2003) 1.22
Silencing of the Pink1 gene expression by conditional RNAi does not induce dopaminergic neuron death in mice. Int J Biol Sci (2007) 1.20
Granulocyte-colony stimulating factor is neuroprotective in a model of Parkinson's disease. J Neurochem (2006) 1.16
Depression comorbidity in spinocerebellar ataxia. Mov Disord (2011) 1.15
Prevention of irradiation-induced glioma cell invasion by temozolomide involves caspase 3 activity and cleavage of focal adhesion kinase. Cancer Res (2002) 1.15
Lesion location alters brain activation in chronically impaired stroke survivors. Neuroimage (2004) 1.14
Relation between regional functional MRI activation and vascular reactivity to carbon dioxide during normal aging. J Cereb Blood Flow Metab (2003) 1.14
Diagnostic hallmarks and pitfalls in late-onset progressive transthyretin-related amyloid-neuropathy. J Neurol (2013) 1.14
Feasibility of prehospital teleconsultation in acute stroke--a pilot study in clinical routine. PLoS One (2012) 1.12
RET signaling does not modulate MPTP toxicity but is required for regeneration of dopaminergic axon terminals. Proc Natl Acad Sci U S A (2007) 1.11
Magnetic resonance imaging-based volumetry differentiates progressive supranuclear palsy from corticobasal degeneration. Neuroimage (2004) 1.10
Hemin toxicity: a preventable source of brain damage following hemorrhagic stroke. Redox Rep (2009) 1.07
Efficient gene therapy for Parkinson's disease using astrocytes as hosts for localized neurotrophic factor delivery. Mol Ther (2011) 1.06
The mitochondrial chaperone protein TRAP1 mitigates α-Synuclein toxicity. PLoS Genet (2012) 1.06
Characterization of motor skill and instrumental learning time scales in a skilled reaching task in rat. Behav Brain Res (2004) 1.05
Accumulation and clearance of alpha-synuclein aggregates demonstrated by time-lapse imaging. J Neurochem (2008) 1.05
Comparison of three clinical rating scales in Friedreich ataxia (FRDA). Mov Disord (2009) 1.04
Gap junction hemichannel-mediated release of glutathione from cultured rat astrocytes. Neurosci Lett (2006) 1.04
Influence of SORL1 gene variants: association with CSF amyloid-beta products in probable Alzheimer's disease. Neurosci Lett (2008) 1.04
Fumaric acid diesters deprive cultured primary astrocytes rapidly of glutathione. Neurochem Int (2010) 1.03
Zinc stimulates the production of toxic reactive oxygen species (ROS) and inhibits glutathione reductase in astrocytes. Free Radic Biol Med (2007) 1.03
Diagnostic challenge and therapeutic dilemma in necrotizing myopathy. Neurology (2013) 1.01
Investigating function and connectivity of morphometric findings--exemplified on cerebellar atrophy in spinocerebellar ataxia 17 (SCA17). Neuroimage (2012) 1.01
Co-enzyme Q10 and idebenone use in Friedreich's ataxia. J Neurochem (2013) 1.01
Genotype-specific patterns of atrophy progression are more sensitive than clinical decline in SCA1, SCA3 and SCA6. Brain (2013) 1.00
Fas/CD95 regulatory protein Faim2 is neuroprotective after transient brain ischemia. J Neurosci (2011) 0.99
Expression of mRNAs of multidrug resistance proteins (Mrps) in cultured rat astrocytes, oligodendrocytes, microglial cells and neurones. J Neurochem (2002) 0.98
Differential effects of iodoacetamide and iodoacetate on glycolysis and glutathione metabolism of cultured astrocytes. Front Neuroenergetics (2009) 0.97
Blood-based neurochemical diagnosis of vascular dementia: a pilot study. J Neurochem (2007) 0.96
Parkinson's disease: one biochemical pathway to fit all genes? Trends Mol Med (2002) 0.96
The proteasomal subunit S6 ATPase is a novel synphilin-1 interacting protein--implications for Parkinson's disease. FASEB J (2007) 0.96
The cancer stem cell subtype determines immune infiltration of glioblastoma. Stem Cells Dev (2012) 0.95
Drosophila melanogaster as a model organism for Alzheimer's disease. Mol Neurodegener (2013) 0.95
Transient expression of Nxf, a bHLH-PAS transactivator induced by neuronal preconditioning, confers neuroprotection in cultured cells. Brain Res (2007) 0.95
Exploring uncoupling proteins and antioxidant mechanisms under acute cold exposure in brains of fish. PLoS One (2011) 0.95
Palmitoylation is a sorting determinant for transport to the myelin membrane. J Cell Sci (2005) 0.94
Alternate-form reliability of the Montreal cognitive assessment screening test in a clinical setting. Dement Geriatr Cogn Disord (2012) 0.94
TRAP1 rescues PINK1 loss-of-function phenotypes. Hum Mol Genet (2013) 0.93
Spinocerebellar ataxia types 1, 2, 3 and 6: the clinical spectrum of ataxia and morphometric brainstem and cerebellar findings. Cerebellum (2012) 0.93
Targeted ablation of oligodendrocytes triggers axonal damage. PLoS One (2011) 0.93
Multidrug resistance protein 1-mediated export of glutathione and glutathione disulfide from brain astrocytes. Methods Enzymol (2005) 0.92
Altered resting-state connectivity in Huntington's disease. Hum Brain Mapp (2013) 0.92
FasL (CD95L/APO-1L) resistance of neurons mediated by phosphatidylinositol 3-kinase-Akt/protein kinase B-dependent expression of lifeguard/neuronal membrane protein 35. J Neurosci (2005) 0.92
Uptake and toxicity of copper oxide nanoparticles in cultured primary brain astrocytes. Nanotoxicology (2013) 0.91
Cortical stimulation mapping using epidurally implanted thin-film microelectrode arrays. J Neurosci Methods (2006) 0.91
Neuroanatomic changes and their association with cognitive decline in mild cognitive impairment: a meta-analysis. Brain Struct Funct (2011) 0.91
Chemotherapy-induced cell death in primary cerebellar granule neurons but not in astrocytes: in vitro paradigm of differential neurotoxicity. J Neurochem (2004) 0.91
CD95/Fas in the brain--not just a killer. Cell Stem Cell (2009) 0.91
Diffusion-weighted MRI in patients with symptomatic internal carotid artery disease. J Neurol (2002) 0.91
Iron accumulation, iron-mediated toxicity and altered levels of ferritin and transferrin receptor in cultured astrocytes during incubation with ferric ammonium citrate. J Neurochem (2004) 0.91
Visualization and quantification of disease progression in multiple system atrophy. Mov Disord (2006) 0.91
Death receptor Fas (CD95) signaling in the central nervous system: tuning neuroplasticity? Trends Neurosci (2008) 0.90
Astrocyte functions in the copper homeostasis of the brain. Neurochem Int (2012) 0.90
Oligodendroglial cells in culture effectively dispose of exogenous hydrogen peroxide: comparison with cultured neurones, astroglial and microglial cells. J Neurochem (2002) 0.90
Formaldehyde in brain: an overlooked player in neurodegeneration? J Neurochem (2013) 0.90
Uptake, metabolism and toxicity of hemin in cultured neurons. Neurochem Int (2011) 0.90
Apoptotic mechanisms and antiapoptotic therapy in the MPTP model of Parkinson's disease. Toxicol Lett (2003) 0.90
Copper accumulation by cultured astrocytes. Neurochem Int (2009) 0.90
Statin therapy at carotid angioplasty and stent placement: effect on procedure-related stroke, myocardial infarction, and death. Radiology (2006) 0.90
The cytosolic redox state of astrocytes: Maintenance, regulation and functional implications for metabolite trafficking. Brain Res Rev (2009) 0.90
Tat-Hsp70 protects dopaminergic neurons in midbrain cultures and in the substantia nigra in models of Parkinson's disease. J Neurochem (2007) 0.90
Zinc prevents the copper-induced damage of cultured astrocytes. Neurochem Int (2010) 0.89
Structure-activity relationships for the impact of selected isothiazol-3-one biocides on glutathione metabolism and glutathione reductase of the human liver cell line Hep G2. Toxicology (2008) 0.88