Published in Arch Biochem Biophys on July 15, 2002
Dissociation of ERK signalling inhibition from the anti-amyloidogenic action of synthetic ceramide analogues. Clin Sci (Lond) (2012) 0.75
Oncogenic mutations of ALK kinase in neuroblastoma. Nature (2008) 5.80
Molecular identification of a renal urate anion exchanger that regulates blood urate levels. Nature (2002) 5.62
Frequent inactivation of A20 in B-cell lymphomas. Nature (2009) 4.22
Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling. Nat Med (2002) 2.61
Prothrombotic coagulation abnormalities preceding the hemolytic-uremic syndrome. N Engl J Med (2002) 2.00
Hepatic Akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvement. Diabetes (2003) 1.86
Coronary atherosclerosis is associated with macrophage polarization in epicardial adipose tissue. J Am Coll Cardiol (2011) 1.68
Carboxy-terminal modulator protein induces Akt phosphorylation and activation, thereby enhancing antiapoptotic, glycogen synthetic, and glucose uptake pathways. Am J Physiol Cell Physiol (2007) 1.65
Blockade of the stromal cell-derived factor-1/CXCR4 axis attenuates in vivo tumor growth by inhibiting angiogenesis in a vascular endothelial growth factor-independent manner. Cancer Res (2005) 1.65
TGF-β-induced mesenchymal transition of MS-1 endothelial cells requires Smad-dependent cooperative activation of Rho signals and MRTF-A. J Biochem (2011) 1.61
A novel mutation in fibroblast growth factor 23 gene as a cause of tumoral calcinosis. J Clin Endocrinol Metab (2005) 1.56
Hyperostosis-hyperphosphatemia syndrome: a congenital disorder of O-glycosylation associated with augmented processing of fibroblast growth factor 23. J Bone Miner Res (2007) 1.52
Patients with Epstein-Fechtner syndromes owing to MYH9 R702 mutations develop progressive proteinuric renal disease. Kidney Int (2010) 1.46
Interstitial deletion of 13q14.13-q32.3 presenting with Arima syndrome and bilateral retinoblastoma. Brain Dev (2010) 1.45
Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p WXXXF/Y motifs are critical for matrix protein import. Mol Cell Biol (2002) 1.42
Shuttling mechanism of peroxisome targeting signal type 1 receptor Pex5: ATP-independent import and ATP-dependent export. Mol Cell Biol (2005) 1.42
Hepatoblastoma in a patient with sotos syndrome. J Pediatr (2009) 1.40
A novel protein kinase B (PKB)/AKT-binding protein enhances PKB kinase activity and regulates DNA synthesis. J Biol Chem (2005) 1.40
Congenital infection-like syndrome with intracranial calcification. Brain Dev (2010) 1.39
In vitro study of patient's and physician's radiation exposure in the performance of epiduroscopy. Reg Anesth Pain Med (2008) 1.39
Fis1, DLP1, and Pex11p coordinately regulate peroxisome morphogenesis. Exp Cell Res (2007) 1.37
Three mitogen-activated protein kinases inhibit insulin signaling by different mechanisms in 3T3-L1 adipocytes. Mol Endocrinol (2002) 1.35
Angiotensin II-induced insulin resistance is associated with enhanced insulin signaling. Hypertension (2002) 1.34
Functional analysis of NBC1 mutants associated with proximal renal tubular acidosis and ocular abnormalities. J Am Soc Nephrol (2005) 1.31
The peroxisomal membrane protein import receptor Pex3p is directly transported to peroxisomes by a novel Pex19p- and Pex16p-dependent pathway. J Cell Biol (2008) 1.25
Differing roles of Akt and serum- and glucocorticoid-regulated kinase in glucose metabolism, DNA synthesis, and oncogenic activity. J Biol Chem (2003) 1.25
Detection, genetic characterization, and quantification of norovirus RNA from sera of children with gastroenteritis. J Clin Virol (2009) 1.23
The pathogenic peroxin Pex26p recruits the Pex1p-Pex6p AAA ATPase complexes to peroxisomes. Nat Cell Biol (2003) 1.20
Mutational and functional analysis of SLC4A4 in a patient with proximal renal tubular acidosis. Pflugers Arch (2004) 1.19
Mutations of the PTPN11 and RAS genes in rhabdomyosarcoma and pediatric hematological malignancies. Genes Chromosomes Cancer (2006) 1.17
Novel class of glycosphingolipids involved in male fertility. J Biol Chem (2005) 1.16
Phosphorylation of Nephrin Triggers Ca2+ Signaling by Recruitment and Activation of Phospholipase C-{gamma}1. J Biol Chem (2009) 1.15
High-salt diet enhances insulin signaling and induces insulin resistance in Dahl salt-sensitive rats. Hypertension (2002) 1.15
Defective membrane expression of the Na(+)-HCO(3)(-) cotransporter NBCe1 is associated with familial migraine. Proc Natl Acad Sci U S A (2010) 1.14
Urinary megalin deficiency implicates abnormal tubular endocytic function in Fanconi syndrome. J Am Soc Nephrol (2002) 1.14
Neph1, a component of the kidney slit diaphragm, is tyrosine-phosphorylated by the Src family tyrosine kinase and modulates intracellular signaling by binding to Grb2. J Biol Chem (2008) 1.14
Functional characterization of LMX1B mutations associated with nail-patella syndrome. Pediatr Res (2005) 1.13
Lewis(y) antigen stimulates the growth of ovarian cancer cells via regulation of the epidermal growth factor receptor pathway. Oncol Rep (2010) 1.11
Ethanol feeding induces insulin resistance with enhanced PI 3-kinase activation. Biochem Biophys Res Commun (2003) 1.10
Exercise-induced acute renal failure associated with renal hypouricaemia: results of a questionnaire-based survey in Japan. Nephrol Dial Transplant (2004) 1.10
OCRL1 mutations in Dent 2 patients suggest a mechanism for phenotypic variability. Nephron Physiol (2009) 1.09
Sec16B is involved in the endoplasmic reticulum export of the peroxisomal membrane biogenesis factor peroxin 16 (Pex16) in mammalian cells. Proc Natl Acad Sci U S A (2011) 1.09
Activation of AMPK is essential for AICAR-induced glucose uptake by skeletal muscle but not adipocytes. Am J Physiol Endocrinol Metab (2002) 1.09
The peroxin Pex14p is involved in LC3-dependent degradation of mammalian peroxisomes. Exp Cell Res (2008) 1.08
Enhancive effects of Lewis y antigen on CD44-mediated adhesion and spreading of human ovarian cancer cell line RMG-I. J Exp Clin Cancer Res (2011) 1.08
Recruitment of the RNA helicase RHAU to stress granules via a unique RNA-binding domain. J Biol Chem (2008) 1.08
Predominant contribution of OATP1B3 to the hepatic uptake of telmisartan, an angiotensin II receptor antagonist, in humans. Drug Metab Dispos (2006) 1.07
The pharmacological characteristics of molecular-based inherited salt-losing tubulopathies. J Clin Endocrinol Metab (2010) 1.07
Cysteine ubiquitination of PTS1 receptor Pex5p regulates Pex5p recycling. Traffic (2011) 1.06
A patient with hypophosphatemic rickets and ossification of posterior longitudinal ligament caused by a novel homozygous mutation in ENPP1 gene. Bone (2011) 1.05
Humoral regulation of resistin expression in 3T3-L1 and mouse adipose cells. Diabetes (2002) 1.05
Functional domain mapping of peroxin Pex19p: interaction with Pex3p is essential for function and translocation. J Cell Sci (2006) 1.05
Investigation of the inhibitory effects of various drugs on the hepatic uptake of fexofenadine in humans. Drug Metab Dispos (2008) 1.04
A novel fluorescent sensor protein for visualization of redox states in the cytoplasm and in peroxisomes. Mol Cell Biol (2010) 1.04
Functional domains and dynamic assembly of the peroxin Pex14p, the entry site of matrix proteins. J Biol Chem (2006) 1.03
Posttranslational regulation of fatty acyl-CoA reductase 1, Far1, controls ether glycerophospholipid synthesis. J Biol Chem (2010) 1.03
Mutational analysis of idiopathic renal hypouricemia in Korea. Pediatr Nephrol (2005) 1.02
Functional characterization of rat organic anion transporter 5 (Slc22a19) at the apical membrane of renal proximal tubules. J Pharmacol Exp Ther (2005) 1.02
Functional analysis of a novel missense NBC1 mutation and of other mutations causing proximal renal tubular acidosis. Pflugers Arch (2007) 1.02
Interaction of myocardial insulin receptor and IGF receptor signaling in exercise-induced cardiac hypertrophy. J Mol Cell Cardiol (2009) 1.01
Lewis y antigen promotes the proliferation of ovarian carcinoma-derived RMG-I cells through the PI3K/Akt signaling pathway. J Exp Clin Cancer Res (2009) 1.00
The membrane biogenesis peroxin Pex16p. Topogenesis and functional roles in peroxisomal membrane assembly. J Biol Chem (2002) 1.00
Intracellular localization, function, and dysfunction of the peroxisome-targeting signal type 2 receptor, Pex7p, in mammalian cells. J Biol Chem (2001) 1.00
Isolation and characterization of mutant animal cell line defective in alkyl-dihydroxyacetonephosphate synthase: localization and transport of plasmalogens to post-Golgi compartments. Biochim Biophys Acta (2008) 1.00
Cyclic strain induces mouse embryonic stem cell differentiation into vascular smooth muscle cells by activating PDGF receptor beta. J Appl Physiol (1985) (2008) 0.99
Peroxisome division is impaired in a CHO cell mutant with an inactivating point-mutation in dynamin-like protein 1 gene. Exp Cell Res (2006) 0.98
In vitro transport of membrane proteins to peroxisomes by shuttling receptor Pex19p. J Biol Chem (2005) 0.98
Ligand-dependent nucleo-cytoplasmic shuttling of peroxisome proliferator-activated receptors, PPARα and PPARγ. Genes Cells (2012) 0.97
Resistin-like molecule beta activates MAPKs, suppresses insulin signaling in hepatocytes, and induces diabetes, hyperlipidemia, and fatty liver in transgenic mice on a high fat diet. J Biol Chem (2005) 0.97
Localization of Na+-HCO-3 cotransporter (NBC-1) variants in rat and human pancreas. Am J Physiol Cell Physiol (2002) 0.97
Tail-anchored PEX26 targets peroxisomes via a PEX19-dependent and TRC40-independent class I pathway. J Cell Biol (2013) 0.97
Promoter-specific repression of hepatocyte nuclear factor (HNF)-1 beta and HNF-1 alpha transcriptional activity by an HNF-1 beta missense mutant associated with Type 5 maturity-onset diabetes of the young with hepatic and biliary manifestations. J Clin Endocrinol Metab (2004) 0.97
Effects of endogenous steroids on CYP3A4-mediated drug metabolism by human liver microsomes. Drug Metab Dispos (2002) 0.96
EYA4, deleted in a case with middle interhemispheric variant of holoprosencephaly, interacts with SIX3 both physically and functionally. Hum Mutat (2009) 0.95
Histamine H2 receptor activation exacerbates myocardial ischemia/reperfusion injury by disturbing mitochondrial and endothelial function. Basic Res Cardiol (2013) 0.95
Activation markers of human basophils: CD69 expression is strongly and preferentially induced by IL-3. J Allergy Clin Immunol (2002) 0.95
Shortage of pediatricians in Japan: a longitudinal analysis using physicians' survey data. Pediatr Int (2009) 0.94
Characteristic expression of globotriaosyl ceramide in human ovarian carcinoma-derived cells with anticancer drug resistance. Cancer Sci (2006) 0.94
[Massive hemorrhage associated with undiagnosed placenta percreta in a second-trimester pregnancy receiving abortion procedure]. Masui (2009) 0.94
Altered polarity and expression of H+-ATPase without ultrastructural changes in kidneys of Dent's disease patients. Kidney Int (2003) 0.94
Aberrations of NEGR1 on 1p31 and MYEOV on 11q13 in neuroblastoma. Cancer Sci (2011) 0.93
Role of hepatic AMPK activation in glucose metabolism and dexamethasone-induced regulation of AMPK expression. Diabetes Res Clin Pract (2006) 0.92
Familial hypophosphatemic rickets caused by a large deletion in PHEX gene. Eur J Endocrinol (2009) 0.92
Decreased glomerular filtration as the primary factor of elevated circulating suPAR levels in focal segmental glomerulosclerosis. Pediatr Nephrol (2014) 0.91
Mutations in novel peroxin gene PEX26 that cause peroxisome-biogenesis disorders of complementation group 8 provide a genotype-phenotype correlation. Am J Hum Genet (2003) 0.91
Detection of ATM gene mutation in human glioma cell line M059J by a rapid frameshift/stop codon assay in yeast. Radiat Res (2002) 0.91
[The effect of colored syringes and a colored sheet on the incidence of syringe swaps during anesthetic management]. Masui (2005) 0.91
Lewis y regulate cell cycle related factors in ovarian carcinoma cell RMG-I in vitro via ERK and Akt signaling pathways. Int J Mol Sci (2012) 0.91
Differential gene responses in endothelial cells exposed to a combination of shear stress and cyclic stretch. J Biotechnol (2007) 0.90
Dynamic and functional assembly of the AAA peroxins, Pex1p and Pex6p, and their membrane receptor Pex26p. J Biol Chem (2006) 0.90
Salt-losing nephrogenic diabetes insipidus caused by fetal exposure to angiotensin receptor blocker. Pediatr Nephrol (2009) 0.90
Pharmacokinetic comparison of an angiotensin II receptor antagonist, telmisartan, in Japanese and western hypertensive patients using population pharmacokinetic method. Drug Metab Pharmacokinet (2004) 0.90
TRAIL-induced cell death cooperates with IFN-gamma activation in the graft-versus-tumor effect against colon tumors. Int J Cancer (2006) 0.90
Study on the expression and clinical significances of lewis y antigen and integrin αv, β3 in epithelial ovarian tumors. Int J Mol Sci (2011) 0.90
Increased Akt-mTOR signaling in lung epithelium is associated with respiratory distress syndrome in mice. Mol Cell Biol (2010) 0.90
Direct interaction between substrates and endogenous steroids in the active site may change the activity of cytochrome P450 3A4. Biochemistry (2003) 0.90
cDNA cloning and characterization of the third isoform of human peroxin Pex11p. Biochem Biophys Res Commun (2003) 0.90
Japanese Dent disease has a wider clinical spectrum than Dent disease in Europe/USA: genetic and clinical studies of 86 unrelated patients with low-molecular-weight proteinuria. Nephrol Dial Transplant (2013) 0.90
The W258X mutation in SLC22A12 is the predominant cause of Japanese renal hypouricemia. Pediatr Nephrol (2004) 0.90