Published in OMICS on January 01, 2002
In planta engineering of viral RNA replicons: efficient assembly by recombination of DNA modules delivered by Agrobacterium. Proc Natl Acad Sci U S A (2004) 2.77
Optimized cDNA libraries for virus-induced gene silencing (VIGS) using tobacco rattle virus. Plant Methods (2008) 0.94
Retracted Virus-induced gene silencing for functional analysis of selected genes. Plant Cell Rep (2007) 0.81
Barley stripe mosaic virus-induced gene silencing in a monocot plant. Plant J (2002) 2.46
Domain-swapped structure of the potent antiviral protein griffithsin and its mode of carbohydrate binding. Structure (2006) 2.16
Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component. Proc Natl Acad Sci U S A (2009) 1.87
High-resolution serum proteomic profiling of Alzheimer disease samples reveals disease-specific, carrier-protein-bound mass signatures. Clin Chem (2005) 1.47
Making an ally from an enemy: plant virology and the new agriculture. Annu Rev Phytopathol (2002) 1.37
Production of pharmaceutical-grade recombinant aprotinin and a monoclonal antibody product using plant-based transient expression systems. Plant Biotechnol J (2010) 1.30
Investigation of griffithsin's interactions with human cells confirms its outstanding safety and efficacy profile as a microbicide candidate. PLoS One (2011) 1.30
Suppressor of RNA silencing encoded by Beet yellows virus. Virology (2003) 1.20
Crystallographic, thermodynamic, and molecular modeling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin. Proteins (2007) 1.20
Modified tobacco mosaic virus particles as scaffolds for display of protein antigens for vaccine applications. Virology (2006) 1.16
Wolman disease/cholesteryl ester storage disease: efficacy of plant-produced human lysosomal acid lipase in mice. J Lipid Res (2008) 1.16
Broad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae. J Virol (2009) 1.15
Griffithsin has antiviral activity against hepatitis C virus. Antimicrob Agents Chemother (2011) 1.14
Protection of rabbits against cutaneous papillomavirus infection using recombinant tobacco mosaic virus containing L2 capsid epitopes. Vaccine (2006) 1.10
Functional modulation of the geminivirus AL2 transcription factor and silencing suppressor by self-interaction. J Virol (2007) 1.07
Griffithsin protects mice from genital herpes by preventing cell-to-cell spread. J Virol (2013) 1.07
Recombinant protein expression in Nicotiana. Methods Mol Biol (2011) 1.05
Improvement of the movement and host range properties of a plant virus vector through DNA shuffling. Plant J (2002) 1.02
Efficient single tobamoviral vector-based bioproduction of broadly neutralizing anti-HIV-1 monoclonal antibody VRC01 in Nicotiana benthamiana plants and utility of VRC01 in combination microbicides. Antimicrob Agents Chemother (2013) 1.00
Geminivirus vectors for high-level expression of foreign proteins in plant cells. Biotechnol Bioeng (2003) 0.99
Activity of and effect of subcutaneous treatment with the broad-spectrum antiviral lectin griffithsin in two laboratory rodent models. Antimicrob Agents Chemother (2013) 0.97
Quantification and extension of transient GFP expression by the co-introduction of a suppressor of silencing. Transgenic Res (2008) 0.96
Quantitative evaluation of six different viral suppressors of silencing using image analysis of transient GFP expression. Plant Cell Rep (2009) 0.95
TMV-peptide fusion vaccines induce cell-mediated immune responses and tumor protection in two murine models. Vaccine (2006) 0.94
Combinations of griffithsin with other carbohydrate-binding agents demonstrate superior activity against HIV Type 1, HIV Type 2, and selected carbohydrate-binding agent-resistant HIV Type 1 strains. AIDS Res Hum Retroviruses (2012) 0.93
Chemical conjugate TMV-peptide bivalent fusion vaccines improve cellular immunity and tumor protection. Bioconjug Chem (2006) 0.93
Occluding the mannose moieties on human immunodeficiency virus type 1 gp120 with griffithsin improves the antibody responses to both proteins in mice. AIDS Res Hum Retroviruses (2011) 0.92
Synergistic activity profile of griffithsin in combination with tenofovir, maraviroc and enfuvirtide against HIV-1 clade C. Virology (2011) 0.91
Genetically engineered Tobacco mosaic virus as nanoparticle vaccines. Expert Rev Vaccines (2008) 0.90
Expression of calreticulin P-domain results in impairment of secretory pathway in Leishmania donovani and reduced parasite survival in macrophages. Int J Parasitol (2002) 0.88
Agroinoculation of the Crinivirus, Lettuce infectious yellows virus, for systemic plant infection. Virology (2009) 0.87
Viable chimaeric viruses confirm the biological importance of sequence specific maize streak virus movement protein and coat protein interactions. Virol J (2008) 0.86
Identification of long intergenic region sequences involved in maize streak virus replication. J Gen Virol (2007) 0.84
RNAi effects on actin mRNAs in Homalodisca vitripennis cells. J RNAi Gene Silencing (2010) 0.84
Chimeras between oilseed rape mosaic virus and tobacco mosaic virus highlight the relevant role of the tobamoviral RdRp as pathogenicity determinant in several hosts. Mol Plant Pathol (2009) 0.84
Assembly of trans-encapsidated recombinant viral vectors engineered from Tobacco mosaic virus and Semliki Forest virus and their evaluation as immunogens. Virology (2006) 0.80
The porcine circovirus type 1 capsid gene promoter improves antigen expression and immunogenicity in a HIV-1 plasmid vaccine. Virol J (2011) 0.79
A distinctive molecular signature of multiple sclerosis derived from MALDI-TOF/MS and serum proteomic pattern analysis: detection of three biomarkers. J Mol Neurosci (2005) 0.79
Development of a plant viral-vector-based gene expression assay for the screening of yeast cytochrome p450 monooxygenases. Assay Drug Dev Technol (2003) 0.77
A multimeric L2 vaccine for prevention of animal papillomavirus infections. Virology (2011) 0.76
Novel plant-derived recombinant human interferons with broad spectrum antiviral activity. Antiviral Res (2011) 0.76