| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Metabolic gene polymorphism frequencies in control populations.
|
Cancer Epidemiol Biomarkers Prev
|
2001
|
3.43
|
|
2
|
Sunshine is good medicine. The health benefits of ultraviolet-B induced vitamin D production.
|
J Cosmet Dermatol
|
2003
|
3.33
|
|
3
|
Glutathione S-transferase polymorphisms and their biological consequences.
|
Pharmacology
|
2000
|
3.01
|
|
4
|
Susceptibility to melanoma: influence of skin type and polymorphism in the melanocyte stimulating hormone receptor gene.
|
J Invest Dermatol
|
1998
|
2.37
|
|
5
|
Basal cell carcinoma.
|
BMJ
|
2003
|
2.10
|
|
6
|
Meta- and pooled analysis of GSTT1 and lung cancer: a HuGE-GSEC review.
|
Am J Epidemiol
|
2006
|
2.02
|
|
7
|
Initial metabolic and hormonal response to acute myocardial infarction.
|
Lancet
|
1974
|
2.02
|
|
8
|
The human glutathione S-transferases: studies on the tissue distribution and genetic variation of the GST1, GST2 and GST3 isozymes.
|
Ann Hum Genet
|
1984
|
1.85
|
|
9
|
Identification of two lithocholic acid-binding proteins. Separation of ligandin from glutathione S-transferase B.
|
Biochem J
|
1979
|
1.71
|
|
10
|
Polymorphism at the glutathione S-transferase GSTP1 locus. A new marker for bronchial hyperresponsiveness and asthma.
|
Am J Respir Crit Care Med
|
2000
|
1.61
|
|
11
|
Potential contribution of the glutathione S-transferase supergene family to resistance to oxidative stress.
|
Free Radic Res
|
1995
|
1.56
|
|
12
|
Exposure to ultraviolet radiation: association with susceptibility and age at presentation with prostate cancer.
|
Lancet
|
2001
|
1.42
|
|
13
|
The development of glutathione S-transferase and glutathione peroxidase activities in human lung.
|
Biochim Biophys Acta
|
1986
|
1.30
|
|
14
|
Glutathione S-transferase polymorphisms in MS: their relationship to disability.
|
Neurology
|
2000
|
1.30
|
|
15
|
GSTM1 null polymorphism at the glutathione S-transferase M1 locus: phenotype and genotype studies in patients with primary biliary cirrhosis.
|
Gut
|
1993
|
1.30
|
|
16
|
A study of the structures of the YaYa and YaYc glutathione S-transferases from rat liver cytosol. Evidence that the Ya monomer is responsible for lithocholate-binding activity.
|
Biochem J
|
1981
|
1.29
|
|
17
|
Glutathione S-transferase GSTT1 genotypes and susceptibility to cancer: studies of interactions with GSTM1 in lung, oral, gastric and colorectal cancers.
|
Carcinogenesis
|
1996
|
1.28
|
|
18
|
Metabolic polymorphisms and cancer susceptibility.
|
Cancer Surv
|
1995
|
1.26
|
|
19
|
Polyadenylation polymorphism in the acetyltransferase 1 gene (NAT1) increases risk of colorectal cancer.
|
Cancer Res
|
1995
|
1.25
|
|
20
|
Polymorphism in cytochrome P450 CYP2D6, CYP1A1, CYP2E1 and glutathione S-transferase, GSTM1, GSTM3, GSTT1 and susceptibility to tobacco-related cancers: studies in upper aerodigestive tract cancers.
|
Pharmacogenetics
|
1998
|
1.25
|
|
21
|
Cholic acid binding by glutathione S-transferases from rat liver cytosol.
|
Biochem J
|
1980
|
1.24
|
|
22
|
The human glutathione S-transferases: developmental aspects of the GST1, GST2, and GST3 loci.
|
Biochem Genet
|
1985
|
1.23
|
|
23
|
Equilibrium-dialysis studies of the interaction between cholic acid and 100000g-supernatant preparations from the rat liver.
|
Biochem J
|
1976
|
1.22
|
|
24
|
Basal cell carcinoma.
|
J R Soc Med
|
1998
|
1.20
|
|
25
|
Glutathione S-transferase GSTM1 phenotypes and protection against cutaneous tumours.
|
Lancet
|
1994
|
1.20
|
|
26
|
Polymorphisms at the glutathione S-transferase, GSTP1 locus: a novel mechanism for susceptibility and development of atopic airway inflammation.
|
Allergy
|
2000
|
1.19
|
|
27
|
Vitamin D receptor polymorphisms are associated with altered prognosis in patients with malignant melanoma.
|
Clin Cancer Res
|
2000
|
1.18
|
|
28
|
Partial purification of two lithocholic acid-binding proteins from rat liver 100 000g supernatants.
|
Biochem J
|
1977
|
1.16
|
|
29
|
Binding of bile acids by 100 000g supernatants from rat liver.
|
Biochem J
|
1977
|
1.16
|
|
30
|
Phenol sulphotransferase SULT1A1 polymorphism: molecular diagnosis and allele frequencies in Caucasian and African populations.
|
Biochem J
|
1999
|
1.15
|
|
31
|
Studies of the development of basic, neutral and acidic isoenzymes of glutathione S-transferase in human liver, adrenal, kidney and spleen.
|
Biochem J
|
1987
|
1.14
|
|
32
|
Use of site-directed mutagenesis of allele-specific PCR primers to identify the GSTM1 A, GSTM1 B, GSTM1 A,B and GSTM1 null polymorphisms at the glutathione S-transferase, GSTM1 locus.
|
Biochem J
|
1993
|
1.08
|
|
33
|
The human glutathione S-transferases. Immunohistochemical studies of the developmental expression of Alpha- and Pi-class isoenzymes in liver.
|
Biochem J
|
1988
|
1.07
|
|
34
|
Polymorphism at the glutathione S-transferase locus GSTM3: interactions with cytochrome P450 and glutathione S-transferase genotypes as risk factors for multiple cutaneous basal cell carcinoma.
|
Cancer Res
|
1996
|
1.06
|
|
35
|
Effects of glutathione S-transferase M1, T1 and P1 on lung function in asthmatic families.
|
Clin Exp Allergy
|
2005
|
1.06
|
|
36
|
Risk factors for basal cell carcinoma in the UK: case-control study in 806 patients.
|
J R Soc Med
|
1997
|
1.06
|
|
37
|
Association of NAD(P)H:quinone oxidoreductase (NQO1) null with numbers of basal cell carcinomas: use of a multivariate model to rank the relative importance of this polymorphism and those at other relevant loci.
|
Carcinogenesis
|
1999
|
1.06
|
|
38
|
Multiple cutaneous basal cell carcinomas: glutathione S-transferase (GSTM1, GSTT1) and cytochrome P450 (CYP2D6, CYP1A1) polymorphisms influence tumour numbers and accrual.
|
Carcinogenesis
|
1996
|
1.03
|
|
39
|
Identification of polymorphism at the glutathione S-transferase, GSTM3 locus: evidence for linkage with GSTM1*A.
|
Biochem J
|
1995
|
1.02
|
|
40
|
Association of polymorphism in glutathione S-transferase loci with susceptibility and outcome in rheumatoid arthritis: comparison with the shared epitope.
|
Ann Rheum Dis
|
1999
|
1.01
|
|
41
|
Association of protein kinase C alpha (PRKCA) gene with multiple sclerosis in a UK population.
|
Brain
|
2004
|
1.00
|
|
42
|
The sources of plasma cyclic AMP: studies in the rat using isoprenaline, nicotinic acid and glucagon.
|
Eur J Clin Invest
|
1975
|
1.00
|
|
43
|
The glutathione S-transferases: polymerase chain reaction studies on the frequency of the GSTM1 0 genotype in patients with pituitary adenomas.
|
Carcinogenesis
|
1993
|
1.00
|
|
44
|
The glyceryl [14C]tripalmitate breath test: a reassessment.
|
Clin Chim Acta
|
1980
|
1.00
|
|
45
|
Interleukin 1 genotypes in multiple sclerosis and relationship to disease severity.
|
J Neuroimmunol
|
2002
|
1.00
|
|
46
|
Multiple basal cell carcinomas and malignant melanoma following radiotherapy for ankylosing spondylitis.
|
Clin Exp Dermatol
|
2000
|
0.99
|
|
47
|
Polymorphisms in CYP1A1, GSTM1, GSTT1 and lung cancer below the age of 45 years.
|
Int J Epidemiol
|
2003
|
0.99
|
|
48
|
Cyclin D1 polymorphism and expression in patients with squamous cell carcinoma of the head and neck.
|
Am J Pathol
|
2001
|
0.98
|
|
49
|
Polymorphism within the cyclin D1 gene is associated with prognosis in patients with squamous cell carcinoma of the head and neck.
|
Clin Cancer Res
|
1998
|
0.97
|
|
50
|
Detoxifying enzyme genotypes and susceptibility to cutaneous malignancy.
|
Br J Dermatol
|
2000
|
0.96
|
|
51
|
Genetics and risk factors for basal cell carcinoma.
|
Br J Dermatol
|
2006
|
0.95
|
|
52
|
A comparison of erythrocyte glutathione S-transferase activity from human foetuses and adults.
|
Biochem J
|
1980
|
0.95
|
|
53
|
Susceptibility and outcome in MS: associations with polymorphisms in pigmentation-related genes.
|
Neurology
|
2004
|
0.95
|
|
54
|
Studies on the variability of glutathione S-transferase from human erythrocytes.
|
Clin Chim Acta
|
1982
|
0.95
|
|
55
|
Plasma alkaline phosphatase activity in rickets of prematurity.
|
Arch Dis Child
|
1982
|
0.94
|
|
56
|
Simultaneous identification of GSTP1 Ile105-->Val105 and Ala114-->Val114 substitutions using an amplification refractory mutation system polymerase chain reaction assay: studies in patients with asthma.
|
Respir Res
|
2001
|
0.94
|
|
57
|
Glutathione S-transferase in human brain.
|
Neuropathol Appl Neurobiol
|
1990
|
0.94
|
|
58
|
Asthma severity and atopy: how clear is the relationship?
|
Arch Dis Child
|
2006
|
0.94
|
|
59
|
Studies on the developmental expression of glutathione S-transferase isoenzymes in human heart and diaphragm.
|
Biochim Biophys Acta
|
1987
|
0.93
|
|
60
|
The -403 G-->A promoter polymorphism in the RANTES gene is associated with atopy and asthma.
|
Genes Immun
|
2000
|
0.93
|
|
61
|
Glutathione S-transferase GSTP1 and cyclin D1 genotypes: association with numbers of basal cell carcinomas in a patient subgroup at high-risk of multiple tumours.
|
Pharmacogenetics
|
2000
|
0.92
|
|
62
|
Interaction between smoking, GSTM1 deletion and colorectal cancer: results from the GSEC study.
|
Biomarkers
|
2003
|
0.92
|
|
63
|
Susceptibility to multiple cutaneous basal cell carcinomas: significant interactions between glutathione S-transferase GSTM1 genotypes, skin type and male gender.
|
Br J Cancer
|
1996
|
0.91
|
|
64
|
Expression and subcellular localization of cyclin D1 protein in epithelial ovarian tumour cells.
|
Br J Cancer
|
1999
|
0.91
|
|
65
|
Prostate cancer risk: associations with ultraviolet radiation, tyrosinase and melanocortin-1 receptor genotypes.
|
Br J Cancer
|
2001
|
0.91
|
|
66
|
Phenol sulphotransferase SULT1A1*1 genotype is associated with reduced risk of colorectal cancer.
|
Pharmacogenetics
|
2001
|
0.89
|
|
67
|
Hepatic bile flow.
|
Physiol Rev
|
1984
|
0.89
|
|
68
|
Cutaneous basal cell carcinomas: distinct host factors are associated with the development of tumors on the trunk and on the head and neck.
|
Cancer
|
2001
|
0.89
|
|
69
|
Polymorphisms in glutathione S-transferases are associated with altered risk of nonmelanoma skin cancer in renal transplant recipients: a preliminary analysis.
|
J Invest Dermatol
|
2001
|
0.88
|
|
70
|
Outcome in prostate cancer associations with skin type and polymorphism in pigmentation-related genes.
|
Carcinogenesis
|
2001
|
0.88
|
|
71
|
Susceptibility to ulcerative colitis and Crohn's disease: interactions between glutathione S-transferase GSTM1 and GSTT1 genotypes.
|
Clin Chim Acta
|
1995
|
0.88
|
|
72
|
The release of adenosine 3':5'-cyclic monophosphate from the isolated perfused rat heart.
|
Biochem J
|
1975
|
0.87
|
|
73
|
Truncal tumor site is associated with high risk of multiple basal cell carcinoma and is influenced by glutathione S-transferase, GSTT1, and cytochrome P450, CYP1A1 genotypes, and their interaction.
|
J Invest Dermatol
|
1997
|
0.87
|
|
74
|
Association between glutathione-S-transferase GSTP1 genotypes, GSTP1 over-expression, and outcome in epithelial ovarian cancer.
|
Int J Gynecol Cancer
|
2004
|
0.87
|
|
75
|
HLA-DRB1 and disease outcome in multiple sclerosis.
|
J Neurol
|
2001
|
0.86
|
|
76
|
Preliminary evidence of an association of tumour necrosis factor microsatellites with increased risk of multiple basal cell carcinomas.
|
Br J Dermatol
|
2000
|
0.86
|
|
77
|
Basal cell carcinomas: association of allelic variants with a high-risk subgroup of patients with the multiple presentation phenotype.
|
Pharmacogenetics
|
2001
|
0.86
|
|
78
|
Partitioning of bile acids into subcellular organelles and the in vivo distribution of bile acids in rat liver.
|
Biochim Biophys Acta
|
1979
|
0.85
|
|
79
|
Truncal site and detoxifying enzyme polymorphisms significantly reduce time to presentation of further primary cutaneous basal cell carcinoma.
|
Carcinogenesis
|
1997
|
0.84
|
|
80
|
A comparison of risk factors for malignant melanoma, squamous cell carcinoma and basal cell carcinoma in the UK.
|
Int J Clin Pract
|
1998
|
0.84
|
|
81
|
Maternal glutathione S-transferase GSTP1 genotype is a specific predictor of phenotype in children with asthma.
|
Pediatr Allergy Immunol
|
2005
|
0.84
|
|
82
|
The glutathione S-transferase GSTP1 polymorphism: effects on susceptibility to oral/pharyngeal and laryngeal carcinomas.
|
Pharmacogenetics
|
1998
|
0.84
|
|
83
|
Glutathione S-transferase GSTM1 and GSTT1 genotypes in ovarian cancer: association with p53 expression and survival.
|
Int J Gynecol Cancer
|
2001
|
0.84
|
|
84
|
Association of glutathione S-transferase GSTM1 and GSTT1 null genotypes with clinical outcome in epithelial ovarian cancer.
|
Clin Cancer Res
|
1998
|
0.83
|
|
85
|
Susceptibility and outcome in oral cancer: preliminary data showing an association with polymorphism in cytochrome P450 CYP2D6.
|
Pharmacogenetics
|
1998
|
0.83
|
|
86
|
Glutathione S-transferase T1 polymorphisms are associated with outcome in colorectal cancer.
|
Carcinogenesis
|
2005
|
0.82
|
|
87
|
A pilot study investigating the role of NAT1 and NAT2 polymorphisms in gastric adenocarcinoma.
|
Int J Cancer
|
2000
|
0.82
|
|
88
|
Brief study of the urinary PABA test for assessment of pancreatic exocrine function.
|
Clin Chem
|
1984
|
0.82
|
|
89
|
The melanocyte stimulating hormone receptor polymorphism: association of the V92M and A294H alleles with basal cell carcinoma.
|
Clin Chim Acta
|
1999
|
0.81
|
|
90
|
Basal cell carcinoma.
|
Cancer
|
2000
|
0.81
|
|
91
|
Susceptibility and modifier genes in cutaneous basal cell carcinomas and their associations with clinical phenotype.
|
J Photochem Photobiol B
|
2001
|
0.81
|
|
92
|
Hepatic bile salt transport. A review of subcellular binding sites.
|
Biochem Soc Trans
|
1981
|
0.81
|
|
93
|
Cyclin D1, glutathione S-transferase, and cytochrome P450 genotypes and outcome in patients with upper aerodigestive tract cancers: assessment of the importance of individual genes using multivariate analysis.
|
Cancer Epidemiol Biomarkers Prev
|
1999
|
0.81
|
|
94
|
Measurements of glutathione S-transferase B1 in plasma after birth asphyxia: an early indication of hepatocellular damage.
|
Clin Chem
|
1989
|
0.81
|
|
95
|
[First results on the influence of polymorphisms at glutathione S-transferase, cytochrome P450, and tumor necrosis factor gene loci on the development of multiple head and neck cancer].
|
Laryngorhinootologie
|
2003
|
0.81
|
|
96
|
Polymorphisms of apolipoprotein E; outcome and susceptibility in multiple sclerosis.
|
Mult Scler
|
2000
|
0.81
|
|
97
|
Progression of cervical intraepithelial neoplasia to cervical cancer: interactions of cytochrome P450 CYP2D6 EM and glutathione s-transferase GSTM1 null genotypes and cigarette smoking.
|
Br J Cancer
|
1994
|
0.80
|
|
98
|
Presentation with multiple cutaneous basal cell carcinomas: association of glutathione S-transferase and cytochrome P450 genotypes with clinical phenotype.
|
Cancer Epidemiol Biomarkers Prev
|
1999
|
0.80
|
|
99
|
A pilot study of the relationship between gadolinium-enhancing lesions, gender effect and polymorphisms of antioxidant enzymes in multiple sclerosis.
|
J Neurol
|
2000
|
0.80
|
|
100
|
Influence of polymorphism in the manganese superoxide dismutase locus on disease outcome in rheumatoid arthritis: evidence for interaction with glutathione S-transferase genes.
|
Arthritis Rheum
|
2000
|
0.80
|
|
101
|
p53 Protein accumulates in Cushings adenomas and invasive non-functional adenomas.
|
J Clin Endocrinol Metab
|
1994
|
0.80
|
|
102
|
A comparison of sunlight exposure in men with prostate cancer and basal cell carcinoma.
|
Br J Cancer
|
2007
|
0.79
|
|
103
|
A constant-volume ultrafiltration technique for the calculation of equilbrium binding data.
|
Biochim Biophys Acta
|
1978
|
0.78
|
|
104
|
Epithelial ovarian cancer: influence of polymorphism at the glutathione S-transferase GSTM1 and GSTT1 loci on p53 expression.
|
Br J Cancer
|
1996
|
0.78
|
|
105
|
Vitamin D receptor gene polymorphism is associated with reduced disability in multiple sclerosis.
|
Mult Scler
|
2008
|
0.78
|
|
106
|
Hepatic clearance of adenosine 3:5-cyclic monophosphate from plasma in the rat.
|
Biochem J
|
1975
|
0.78
|
|
107
|
The effect of glucagon on plasma cyclic AMP and glucose concentrations in patients with alcoholic cirrhosis.
|
Acta Med Scand
|
1977
|
0.78
|
|
108
|
Assessment of liver function using fasting bile salt concentrations in psoriasis prior to and during methotrexate therapy.
|
Clin Chim Acta
|
1983
|
0.78
|
|
109
|
Patients with truncal basal cell carcinoma represent a high-risk group.
|
Arch Dermatol
|
1998
|
0.78
|
|
110
|
A comparison of the glutathione S-transferases of trout and rat liver.
|
Comp Biochem Physiol B
|
1979
|
0.78
|
|
111
|
Alpha, mu and pi class glutathione S-transferases in human synovium and cultured synovial fibroblasts: effects of interleukin-1 alpha, hydrogen peroxide and inhibition of eicosanoid synthesis.
|
Free Radic Res Commun
|
1993
|
0.78
|
|
112
|
Basal cell carcinoma: from host response and polymorphic variants to tumour suppressor genes.
|
Clin Exp Dermatol
|
2005
|
0.77
|
|
113
|
An evaluation of ways of using equilibrium dialysis to quantify the binding of ligand to macromolecule.
|
Biochem J
|
1977
|
0.77
|
|
114
|
Interactions of hydrogen peroxide with interleukin-6 and platelet-derived growth factor in determining mesangial cell growth: effect of repeated oxidant stress.
|
Clin Sci (Lond)
|
1993
|
0.77
|
|
115
|
P53 protein accumulates in Cushings adenomas and invasive non-functional adenomas.
|
J Clin Endocrinol Metab
|
1995
|
0.77
|
|
116
|
Interleukin-10 (IL10) promoter polymorphisms and multiple sclerosis.
|
J Neuroimmunol
|
1999
|
0.77
|
|
117
|
[Effect of gene polymorphism on detoxifying glutathione-S-transferase enzymes on chromosomal stability of squamous epithelial carcinomas in the area of the head-neck].
|
Laryngorhinootologie
|
1998
|
0.77
|
|
118
|
Multiple basal cell carcinomas in a patient with acute myeloid leukaemia and chronic lymphocytic leukaemia.
|
Clin Exp Dermatol
|
1999
|
0.77
|
|
119
|
Regional variation of airway hyperresponsiveness in children with asthma.
|
Respir Med
|
2005
|
0.77
|
|
120
|
[Genetic predisposition for the development of head and neck carcinomas].
|
Laryngorhinootologie
|
1999
|
0.77
|
|
121
|
Allelism at the glutathione S-transferase GSTM3 locus: interactions with GSTM1 and GSTT1 as risk factors for astrocytoma.
|
Carcinogenesis
|
1996
|
0.77
|
|
122
|
No association between the APOE epsilon4 allele and outcome and susceptibility in primary progressive multiple sclerosis.
|
J Neurol Neurosurg Psychiatry
|
2000
|
0.76
|
|
123
|
Genetic factors determining cutaneous basal cell carcinoma phenotype.
|
Med Pediatr Oncol
|
2001
|
0.76
|
|
124
|
The therapeutic response to D-penicillamine in rheumatoid arthritis: influence of glutathione S-transferase polymorphisms.
|
Rheumatology (Oxford)
|
1999
|
0.76
|
|
125
|
Localisation of alpha, mu and pi class glutathione S-transferases in kidney: comparison with CuZn superoxide dismutase.
|
Biochim Biophys Acta
|
1993
|
0.76
|
|
126
|
Human glutathione S-transferases: radioimmunoassay studies on the expression of alpha-, mu- and pi-class isoenzymes in developing lung and kidney.
|
Biochim Biophys Acta
|
1990
|
0.75
|
|
127
|
Immunocytochemical studies of the distribution of alpha and pi isoforms of glutathione S-transferase in cystic renal diseases.
|
Pediatr Pathol
|
1994
|
0.75
|
|
128
|
Erythrocyte glutathione S-transferase. Electrophoretic identification of two enzyme forms.
|
Biochem J
|
1983
|
0.75
|
|
129
|
Prognostic factors for a subsequent basal cell carcinoma: implications for follow-up.
|
Br J Dermatol
|
2006
|
0.75
|
|
130
|
An association study between the Clara cell secretory protein CC16 A38G polymorphism and asthma phenotypes.
|
Clin Exp Allergy
|
2002
|
0.75
|
|
131
|
Nuclear and cytosolic distribution of conjugated cholic acid and radiolabelled glycocholic acid in rat liver.
|
Biochem J
|
1979
|
0.75
|
|
132
|
Non-Hodgkins lymphoma and solar ultraviolet radiation. Basal cell carcinoma may be linked to haematological malignancy.
|
BMJ
|
1996
|
0.75
|
|
133
|
Glutathione S-transferase expression in primary biliary cirrhosis supports concept of "ductular metaplasia" of hepatocytes.
|
J Clin Pathol
|
1993
|
0.75
|
|
134
|
Lack of relation between venous plasma total catecholamine concentrations and ventricular arrhythmias after acute myocardial infarction.
|
Br Med J
|
1978
|
0.75
|
|
135
|
Studies in the rat on the hepatic subcellular distribution and billary excretion of lithocholic acid.
|
Biochim Biophys Acta
|
1979
|
0.75
|
|
136
|
[Immunohistologic and molecular genetic studies of the effect of glutathione-S-transferases on the development of squamous epithelial carcinomas in the area of the head-neck].
|
Laryngorhinootologie
|
1999
|
0.75
|
|
137
|
Binding of bile acids to 100000g supernatants from rat liver.
|
Biochem Soc Trans
|
1976
|
0.75
|
|
138
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