Published in Int J Oncol on September 01, 2002
CCL2 protects prostate cancer PC3 cells from autophagic death via phosphatidylinositol 3-kinase/AKT-dependent survivin up-regulation. J Biol Chem (2008) 1.71
Hypericin-mediated photodynamic therapy induces apoptosis of myoloma SP2/0 cells depended on caspase activity in vitro. Cancer Cell Int (2014) 1.42
Effect and mechanism of 5-aminolevulinic acid-mediated photodynamic therapy in esophageal cancer. Lasers Med Sci (2010) 0.89
St John's Wort (Hypericum perforatum L.) photomedicine: hypericin-photodynamic therapy induces metastatic melanoma cell death. PLoS One (2014) 0.87
Secondary plant products causing photosensitization in grazing herbivores: their structure, activity and regulation. Int J Mol Sci (2014) 0.84
Necrosis avidity: a newly discovered feature of hypericin and its preclinical applications in necrosis imaging. Theranostics (2013) 0.83
Hypericin in the Light and in the Dark: Two Sides of the Same Coin. Front Plant Sci (2016) 0.79
In vitro comparison of hypericin and 5-aminolevulinic acid-derived protoporphyrin IX for photodynamic inactivation of medulloblastoma cells. PLoS One (2012) 0.77
Photoactivation of hypericin decreases the viability of RINm5F insulinoma cells through reduction in JNK/ERK phosphorylation and elevation of caspase-9/caspase-3 cleavage and Bax-to-Bcl-2 ratio. Biosci Rep (2015) 0.76
Coblation plus photodynamic therapy (PDT) for the treatment of juvenile onset laryngeal papillomatosis: case reports. World J Surg Oncol (2014) 0.75
Development of a multifunctional luciferase reporters system for assessing endoplasmic reticulum-targeting photosensitive compounds. Cell Stress Chaperones (2014) 0.75
Photodynamic therapy with a novel porphyrin-based photosensitizer against human gastric cancer. Oncol Lett (2015) 0.75
Photosensitizing effects of hypericin on head neck squamous cell carcinoma in vitro. Eur Arch Otorhinolaryngol (2014) 0.75
Photodynamic efficacy of hypericin targeted by two delivery techniques to hepatocellular carcinoma cells. Lasers Med Sci (2010) 0.75
Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells. Nat Immunol (2013) 1.95
The effect of photodynamic therapy on tumor angiogenesis. Cell Mol Life Sci (2009) 1.62
Chlorin e6-polyvinylpyrrolidone mediated photodynamic therapy--A potential bladder sparing option for high risk non-muscle invasive bladder cancer. Photodiagnosis Photodyn Ther (2010) 1.45
Reduced graphene oxide conjugated Cu2O nanowire mesocrystals for high-performance NO2 gas sensor. J Am Chem Soc (2012) 1.38
Photodynamic-therapy-activated immune response against distant untreated tumours in recurrent angiosarcoma. Lancet Oncol (2007) 1.29
Laser confocal endomicroscopy as a novel technique for fluorescence diagnostic imaging of the oral cavity. J Biomed Opt (2007) 1.25
Ultrasensitive near-infrared Raman reporters for SERS-based in vivo cancer detection. Angew Chem Int Ed Engl (2011) 1.18
Head & neck optical diagnostics: vision of the future of surgery. Head Neck Oncol (2009) 1.05
Critical parameters in the pegylation of gold nanoshells for biomedical applications: an in vitro macrophage study. J Drug Target (2009) 1.01
Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters. Chem Commun (Camb) (2011) 0.99
Art and science of photodynamic therapy. Clin Exp Pharmacol Physiol (2006) 0.99
The future of medical diagnostics: review paper. Head Neck Oncol (2011) 0.97
Hypocrellins and Hypericin induced apoptosis in human tumor cells: a possible role of hydrogen peroxide. Int J Mol Med (2002) 0.95
Combinatorial treatment of photothermal therapy using gold nanoshells with conventional photodynamic therapy to improve treatment efficacy: an in vitro study. Lasers Surg Med (2008) 0.94
Development of biocompatible SERS nanotag with increased stability by chemisorption of reporter molecule for in vivo cancer detection. Biosens Bioelectron (2010) 0.94
Hypericin-mediated photodynamic therapy in combination with Avastin (bevacizumab) improves tumor response by downregulating angiogenic proteins. Photochem Photobiol Sci (2007) 0.92
Concentration dependence of gold nanoshells on the enhancement of optical coherence tomography images: a quantitative study. Appl Opt (2009) 0.92
The use of digitized endoscopic imaging of 5-ALA-induced PPIX fluorescence to detect and diagnose oral premalignant and malignant lesions in vivo. Int J Cancer (2004) 0.91
Clinical SERS: are we there yet? J Biophotonics (2011) 0.90
Chlorin e6-polyvinylpyrrolidone as a fluorescent marker for fluorescence diagnosis of human bladder cancer implanted on the chick chorioallantoic membrane model. Cancer Lett (2006) 0.90
Targeting EGFR with photodynamic therapy in combination with Erbitux enhances in vivo bladder tumor response. Mol Cancer (2009) 0.90
Development of highly reproducible nanogap SERS substrates: comparative performance analysis and its application for glucose sensing. Biosens Bioelectron (2010) 0.89
Hypericin-photodynamic therapy (PDT) using an alternative treatment regime suitable for multi-fraction PDT. J Photochem Photobiol B (2005) 0.89
Immune response against angiosarcoma following lower fluence rate clinical photodynamic therapy. J Environ Pathol Toxicol Oncol (2008) 0.89
Improved formulation of photosensitizer chlorin e6 polyvinylpyrrolidone for fluorescence diagnostic imaging and photodynamic therapy of human cancer. Eur J Pharm Biopharm (2008) 0.88
Highly sensitive SERS detection of cancer proteins in low sample volume using hollow core photonic crystal fiber. Biosens Bioelectron (2012) 0.88
Hypericin-mediated photodynamic therapy elicits differential interleukin-6 response in nasopharyngeal cancer. Cancer Lett (2005) 0.88
Fluorescence imaging and phototoxicity effects of new formulation of chlorin e6-polyvinylpyrrolidone. J Photochem Photobiol B (2006) 0.87
Hypericin-mediated photodynamic therapy induces lipid peroxidation and necrosis in nasopharyngeal cancer. Int J Oncol (2003) 0.87
Enhancing the therapeutic responsiveness of photodynamic therapy with the antiangiogenic agents SU5416 and SU6668 in murine nasopharyngeal carcinoma models. Cancer Chemother Pharmacol (2005) 0.87
The potential application of chlorin e6-polyvinylpyrrolidone formulation in photodynamic therapy. Photochem Photobiol Sci (2006) 0.86
Anti-angiogenic effects of Hypericin-photodynamic therapy in combination with Celebrex in the treatment of human nasopharyngeal carcinoma. Int J Mol Med (2005) 0.86
Optimal excitation-emission wavelengths for autofluorescence diagnosis of bladder tumors. Int J Cancer (2003) 0.85
Control of optical contrast using gold nanoshells for optical coherence tomography imaging of mouse xenograft tumor model in vivo. J Biomed Opt (2009) 0.85
Evaluation of hypericin-mediated photodynamic therapy in combination with angiogenesis inhibitor bevacizumab using in vivo fluorescence confocal endomicroscopy. J Biomed Opt (2010) 0.85
Confocal endomicroscopic imaging of normal and neoplastic human tongue tissue using ALA-induced-PPIX fluorescence: a preliminary study. Oncol Rep (2004) 0.85
Molecular profiling of angiogenesis in hypericin mediated photodynamic therapy. Mol Cancer (2008) 0.84
Photolon™ --photosensitization induces apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes. Int J Oncol (2011) 0.83
Fluorescence detection of bladder cancer using urine cytology. Int J Oncol (2007) 0.83
Frequency shifts in SERS for biosensing. ACS Nano (2012) 0.83
At the frontiers of surgery: review. Head Neck Oncol (2011) 0.83
Efficacy of hypocrellin pharmacokinetics in phototherapy. Int J Oncol (2002) 0.83
Sensitive multiplex detection of serological liver cancer biomarkers using SERS-active photonic crystal fiber probe. J Biophotonics (2013) 0.83
Polymer-based microfluidics with surface-enhanced Raman-spectroscopy-active periodic metal nanostructures for biofluid analysis. J Biomed Opt (2008) 0.83
Is photodynamic diagnosis using hypericin better than white-light cystoscopy for detecting superficial bladder carcinoma? BJU Int (2005) 0.82
Detection of squamous cell carcinomas and pre-cancerous lesions in the oral cavity by quantification of 5-aminolevulinic acid induced fluorescence endoscopic images. Lasers Surg Med (2002) 0.82
Chlorin e6 - polyvinylpyrrolidone mediated photosensitization is effective against human non-small cell lung carcinoma compared to small cell lung carcinoma xenografts. BMC Pharmacol (2007) 0.81
Investigation into a surface plasmon related heating effect in surface enhanced Raman spectroscopy. Anal Chem (2007) 0.81
Photodynamic therapy induced Fas-mediated apoptosis in human carcinoma cells. Int J Mol Med (2002) 0.81
Quantum dot capped magnetite nanorings as high performance nanoprobe for multiphoton fluorescence and magnetic resonance imaging. J Am Chem Soc (2010) 0.81
Endogenous expression of interleukin-8 and interleukin-10 in nasopharyngeal carcinoma cells and the effect of photodynamic therapy. Int J Mol Med (2002) 0.81
Antiangiogenesis agents avastin and erbitux enhance the efficacy of photodynamic therapy in a murine bladder tumor model. Lasers Surg Med (2011) 0.81
Effect of hypericin-mediated photodynamic therapy on the expression of vascular endothelial growth factor in human nasopharyngeal carcinoma. Int J Mol Med (2007) 0.81
Endoscopic image analysis of photosensitizer fluorescence as a promising noninvasive approach for pathological grading of bladder cancer in situ. J Biomed Opt (2008) 0.81
Detection of neoplasms in the oral cavity by digitized endoscopic imaging of 5-aminolevulinic acid-induced protoporphyrin IX fluorescence. Int J Oncol (2002) 0.80
Photodynamic diagnosis of a human nasopharyngeal carcinoma xenograft model using the novel Chlorin e6 photosensitizer Fotolon. Int J Oncol (2005) 0.80
Engineering bioconjugated gold nanospheres and gold nanorods as label-free plasmon scattering probes for ultrasensitive multiplex dark-field imaging of cancer cells. J Biomed Nanotechnol (2013) 0.80
Nitric oxide mediated photo-induced cell death in human malignant cells. Int J Oncol (2003) 0.80
Membrane transport enhancement of chlorin e6-polyvinylpyrrolidone and its photodynamic efficacy on the chick chorioallantoic model. J Biophotonics (2008) 0.80
Metal carbonyl-gold nanoparticle conjugates for live-cell SERS imaging. Angew Chem Int Ed Engl (2012) 0.80
Evaluation of Hypocrellin B in a human bladder tumor model in experimental photodynamic therapy: biodistribution, light dose and drug-light interval effects. Int J Oncol (2004) 0.80
Transport of hypericin across chick chorioallantoic membrane and photodynamic therapy vasculature assessment. Biol Pharm Bull (2005) 0.79
Biodistribution and photodynamic therapy with hypericin in a human NPC murine tumor model. Int J Oncol (2003) 0.79
Potentiation of the photodynamic action of hypericin. J Environ Pathol Toxicol Oncol (2008) 0.78
A study of 5-aminolevulinic acid and its methyl ester used in in vitro and in vivo systems of human bladder cancer. Int J Oncol (2003) 0.78
Modulation of Matrix metalloproteinase-1 in nasopharyngeal cancer cells by photoactivation of hypericin. Int J Oncol (2004) 0.78
Delivery of hypericin for photodynamic applications. Cancer Lett (2005) 0.78
Mechanisms of action of phenanthroperylenequinones in photodynamic therapy (review). Int J Oncol (2003) 0.78
Photodynamic-induced vascular damage of the chick chorioallantoic membrane model using perylenequinones. Int J Oncol (2004) 0.77
Organometallic carbonyl clusters: a new class of contrast agents for photoacoustic cerebral vascular imaging. Chem Commun (Camb) (2014) 0.77
Imaging metabolic syndrome. EMBO Mol Med (2010) 0.77
Superiority of N-methyl pyrrolidone over albumin with hypericin for fluorescence diagnosis of human bladder cancer cells implanted in the chick chorioallantoic membrane model. J Photochem Photobiol B (2006) 0.77
Enhanced photodynamic activity of hypericin by penetration enhancer N-methyl pyrrolidone formulations in the chick chorioallantoic membrane model. Cancer Lett (2005) 0.77
A study comparing endogenous protoporphyrin IX induced by 5-ALA and ALA-methyl ester with exogenous PpIX and PpIX dimethyl ester in photodynamic diagnosis of human nasopharyngeal carcinoma xenografts. Int J Oncol (2006) 0.77
In-vivo optical detection of cancer using chlorin e6--polyvinylpyrrolidone induced fluorescence imaging and spectroscopy. BMC Med Imaging (2009) 0.77
Spectroscopic characterization and photobleaching kinetics of hypericin-N-methyl pyrrolidone formulations. Photochem Photobiol Sci (2006) 0.77
Toward real-time virtual biopsy of oral lesions using confocal laser endomicroscopy interfaced with embedded computing. J Biomed Opt (2012) 0.77
Expression of Y-Box binding protein-1 following hypericin-mediated photodynamic therapy in well-differentiated nasopharyngeal cancer in vivo. Int J Mol Med (2005) 0.77
Recent progress in voltage-sensitive dye imaging for neuroscience. J Nanosci Nanotechnol (2014) 0.76
A transition metal carbonyl probe for use in a highly specific and sensitive SERS-based assay for glucose. J Am Chem Soc (2013) 0.76
Differential up-regulation of metallothionein isoforms in well-differentiated nasopharyngeal cancer cells in vitro by photoactivated hypericin. Oncol Rep (2006) 0.76
Hypericin induced death receptor-mediated apoptosis in photoactivated tumor cells. Int J Mol Med (2002) 0.76
A rapid and label-free SERS detection method for biomarkers in clinical biofluids. Small (2014) 0.76
Dynamic quantitative photothermal monitoring of cell death of individual human red blood cells upon glucose depletion. J Biomed Opt (2010) 0.76
Combinatorial synthesis of a triphenylmethine library and their application in the development of surface enhanced Raman scattering (SERS) probes. Chem Commun (Camb) (2009) 0.76
Effect of polyvinylpyrrolidone on the interaction of chlorin e6 with plasma proteins and its subcellular localization. Eur J Pharm Biopharm (2010) 0.75
Amplified spontaneous emission from single CdS nanoribbon with low symmetric cross sections. Nanoscale (2012) 0.75
Nanosphere templated metallic grating assisted enhanced fluorescence. J Fluoresc (2011) 0.75
Effect of input states of polarization on the measurement error of Mueller matrix in a system having small polarization-dependent loss or gain. Opt Express (2009) 0.75
A comparison of protoporphyrin IX and protoporphyrin IX dimethyl ester as a photosensitizer in poorly differentiated human nasopharyngeal carcinoma cells. Photochem Photobiol (2002) 0.75
Optimum input states of polarization for Mueller matrix measurement in a system having finite polarization-dependent loss or gain. Opt Express (2009) 0.75
Apoptosis induced by photosensitizers (Perylquinone derivatives) in human carcinoma cells: a possible relevance to photodynamic therapy. Asian J Surg (2002) 0.75
Macro-microscopic fluorescence imaging of human NPC xenografts in a murine model using topical vs intravenous administration of 5-aminolevulinic acid. Int J Oncol (2002) 0.75
Erratum. Retinoic Acid Mediates Visceral-Specific Adipogenic Defects of Human Adipose-Derived Stem Cells. Diabetes 2016;65:1164-1178. Diabetes (2016) 0.75
Effects of N-methyl pyrrolidone on the uptake of hypericin in human bladder carcinoma and co-staining with DAPI investigated by confocal microscopy. Technol Cancer Res Treat (2007) 0.75
Sub-micron free-standing metal slabs with dielectric nano-voids of arbitrary shapes embedded beneath atomically-flat surface. Opt Express (2011) 0.75
Deposition method for preparing SERS-active gold nanoparticle substrates. Anal Chem (2005) 0.75
Study of interaction of hypericin and its pharmaceutical preparation by fluorescence techniques. J Biomed Opt (2009) 0.75
An evaluation of exogenous application of protoporphyrin IX and its dimethyl ester as a photodynamic diagnostic agent in poorly differentiated human nasopharyngeal carcinoma. Photochem Photobiol (2004) 0.75
Colorimetric surface plasmon resonance imaging (SPRI) biosensor array based on polarization orientation. Biosens Bioelectron (2013) 0.75