Published in Mech Dev on June 01, 2002
In vivo genetic ablation by Cre-mediated expression of diphtheria toxin fragment A. Genesis (2005) 2.08
Lack of the murine homeobox gene Hesx1 leads to a posterior transformation of the anterior forebrain. Development (2007) 1.07
Candidate gene screen in the red flour beetle Tribolium reveals six3 as ancient regulator of anterior median head and central complex development. PLoS Genet (2011) 0.99
Fgf8b-containing spliceforms, but not Fgf8a, are essential for Fgf8 function during development of the midbrain and cerebellum. Dev Biol (2009) 0.93
Neonatal lethality, dwarfism, and abnormal brain development in Dmbx1 mutant mice. Mol Cell Biol (2004) 0.84
Dmbx1 is essential in agouti-related protein action. Proc Natl Acad Sci U S A (2007) 0.81
Tandem organization of independently duplicated homeobox genes in the basal cnidarian Acropora millepora. Dev Genes Evol (2005) 0.78
A catalog of Xenopus tropicalis transcription factors and their regional expression in the early gastrula stage embryo. Dev Biol (2016) 0.78
Duplicate dmbx1 genes regulate progenitor cell cycle and differentiation during zebrafish midbrain and retinal development. BMC Dev Biol (2010) 0.77
Coordinating progenitor cell cycle exit and differentiation in the developing vertebrate retina. Neurogenesis (Austin) (2016) 0.75
Compartments and their boundaries in vertebrate brain development. Nat Rev Neurosci (2005) 2.01
A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo. Development (2006) 1.79
Hedgehog signaling from the ZLI regulates diencephalic regional identity. Nat Neurosci (2004) 1.60
Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain. Development (2004) 1.59
Otx2 regulates subtype specification and neurogenesis in the midbrain. J Neurosci (2005) 1.59
Orthopedia homeodomain protein is essential for diencephalic dopaminergic neuron development. Curr Biol (2007) 1.58
Folic acid prevents exencephaly in Cited2 deficient mice. Hum Mol Genet (2002) 1.55
Zebrafish atlastin controls motility and spinal motor axon architecture via inhibition of the BMP pathway. Nat Neurosci (2010) 1.52
Subcortical visual shell nuclei targeted by ipRGCs develop from a Sox14+-GABAergic progenitor and require Sox14 to regulate daily activity rhythms. Neuron (2012) 1.51
Analysis of spatial and temporal gene expression patterns in blastula and gastrula stage chick embryos. Dev Biol (2002) 1.48
Hedgehog signalling from the zona limitans intrathalamica orchestrates patterning of the zebrafish diencephalon. Development (2006) 1.38
The Otx family. Curr Opin Genet Dev (2002) 1.31
Over- and underdosage of SOX3 is associated with infundibular hypoplasia and hypopituitarism. Am J Hum Genet (2005) 1.29
RALDH-independent generation of retinoic acid during vertebrate embryogenesis by CYP1B1. Development (2007) 1.28
Anterior-posterior graded response to Otx2 controls proliferation and differentiation of dopaminergic progenitors in the ventral mesencephalon. Development (2008) 1.28
Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP. Nat Neurosci (2010) 1.22
Adrenal development is initiated by Cited2 and Wt1 through modulation of Sf-1 dosage. Development (2007) 1.19
Otx dose-dependent integrated control of antero-posterior and dorso-ventral patterning of midbrain. Nat Neurosci (2003) 1.19
Otx2 is an intrinsic determinant of the embryonic stem cell state and is required for transition to a stable epiblast stem cell condition. Development (2012) 1.18
Building a bridal chamber: development of the thalamus. Trends Neurosci (2010) 1.18
Otx2 expression is restricted to dopaminergic neurons of the ventral tegmental area in the adult brain. Int J Dev Biol (2010) 1.16
A neuronal migratory pathway crossing from diencephalon to telencephalon populates amygdala nuclei. Nat Neurosci (2010) 1.15
Loss of glutamatergic pyramidal neurons in frontal and temporal cortex resulting from attenuation of FGFR1 signaling is associated with spontaneous hyperactivity in mice. J Neurosci (2004) 1.13
Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome. EMBO Mol Med (2012) 1.13
The prepattern transcription factor Irx2, a target of the FGF8/MAP kinase cascade, is involved in cerebellum formation. Nat Neurosci (2004) 1.11
The role of organizers in patterning the nervous system. Annu Rev Neurosci (2012) 1.11
Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain. Development (2009) 1.11
Location and size of dopaminergic and serotonergic cell populations are controlled by the position of the midbrain-hindbrain organizer. J Neurosci (2003) 1.10
Otx1l, Otx2 and Irx1b establish and position the ZLI in the diencephalon. Development (2007) 1.09
Lhx2 and Lhx9 determine neuronal differentiation and compartition in the caudal forebrain by regulating Wnt signaling. PLoS Biol (2011) 1.09
Expression analysis of chick Wnt and frizzled genes and selected inhibitors in early chick patterning. Dev Dyn (2004) 1.07
Combined deficiency of alpha and epsilon sarcoglycan disrupts the cardiac dystrophin complex. Hum Mol Genet (2011) 1.05
The transcription factor orthodenticle homeobox 2 influences axonal projections and vulnerability of midbrain dopaminergic neurons. Brain (2010) 1.04
The transcription factor Otx2 regulates choroid plexus development and function. Development (2013) 1.04
No evidence for ventrally migrating neural tube cells from the mid- and hindbrain. Dev Dyn (2002) 1.03
Tbx22null mice have a submucous cleft palate due to reduced palatal bone formation and also display ankyloglossia and choanal atresia phenotypes. Hum Mol Genet (2009) 1.02
Novel FGF8 mutations associated with recessive holoprosencephaly, craniofacial defects, and hypothalamo-pituitary dysfunction. J Clin Endocrinol Metab (2011) 1.02
Intrinsic, Hox-dependent cues determine the fate of skeletal muscle precursors. Dev Cell (2003) 1.02
The H3K27 demethylase JMJD3 is required for maintenance of the embryonic respiratory neuronal network, neonatal breathing, and survival. Cell Rep (2012) 1.01
Otx2 controls identity and fate of glutamatergic progenitors of the thalamus by repressing GABAergic differentiation. J Neurosci (2006) 1.01
Variations in PROKR2, but not PROK2, are associated with hypopituitarism and septo-optic dysplasia. J Clin Endocrinol Metab (2013) 1.01
The migration of cerebellar rhombic lip derivatives. Development (2002) 0.98
Neural crest cells provide species-specific patterning information in the developing branchial skeleton. Evol Dev (2004) 0.98
Her6 regulates the neurogenetic gradient and neuronal identity in the thalamus. Proc Natl Acad Sci U S A (2009) 0.98
Foxg1 is required for proper separation and formation of sensory cristae during inner ear development. Dev Dyn (2009) 0.97
Otx genes in the evolution of the vertebrate brain. Brain Res Bull (2005) 0.95
Rhombomere-specific analysis reveals the repertoire of genetic cues expressed across the developing hindbrain. Neural Dev (2009) 0.94
Fgf15-mediated control of neurogenic and proneural gene expression regulates dorsal midbrain neurogenesis. Dev Biol (2010) 0.93
Differentiation of cerebellar cell identities in absence of Fgf signalling in zebrafish Otx morphants. Development (2006) 0.92
Complex and dynamic patterns of Wnt pathway gene expression in the developing chick forebrain. Neural Dev (2009) 0.92
Irx3 and Pax6 establish differential competence for Shh-mediated induction of GABAergic and glutamatergic neurons of the thalamus. Proc Natl Acad Sci U S A (2013) 0.92
Altered dopaminergic innervation and amphetamine response in adult Otx2 conditional mutant mice. Mol Cell Neurosci (2005) 0.92
Wnt6 marks sites of epithelial transformations in the chick embryo. Mech Dev (2002) 0.92
Gbx2 and Otx2 interact with the WD40 domain of Groucho/Tle corepressors. Mol Cell Biol (2006) 0.91
Embryonic defects and growth alteration in mice with homozygous disruption of the Patz1 gene. J Cell Physiol (2013) 0.90
Arcuate plan of chick midbrain development. J Neurosci (2002) 0.88
Apoptosis of premigratory neural crest cells in rhombomeres 3 and 5: consequences for patterning of the branchial region. Dev Biol (2002) 0.88
Development of the early axon scaffold in the rostral brain of the chick embryo. J Anat (2011) 0.88
Induction of a parafacial rhythm generator by rhombomere 3 in the chick embryo. J Neurosci (2004) 0.88
PRDC regulates placode neurogenesis in chick by modulating BMP signalling. Dev Biol (2009) 0.88
Evolutionary conservation of otd/Otx2 transcription factor action: a genome-wide microarray analysis in Drosophila. Genome Biol (2002) 0.87
Isolation and expression of the homeobox gene Gbx1 during mouse development. Dev Dyn (2004) 0.86
The role of otx2 in adult mesencephalic-diencephalic dopaminergic neurons. Mol Neurobiol (2010) 0.85
Graded Otx2 activities demonstrate dose-sensitive eye and retina phenotypes. Hum Mol Genet (2013) 0.85
An evolutionarily conserved Myostatin proximal promoter/enhancer confers basal levels of transcription and spatial specificity in vivo. Dev Genes Evol (2010) 0.85
Tissue interactions in the developing chick diencephalon. Neural Dev (2007) 0.84
Sp8 controls the anteroposterior patterning at the midbrain-hindbrain border. Development (2006) 0.84
ARNT2 mutation causes hypopituitarism, post-natal microcephaly, visual and renal anomalies. Brain (2013) 0.84
Expression of the brain transcription factor OTX1 occurs in a subset of normal germinal-center B cells and in aggressive Non-Hodgkin Lymphoma. Am J Pathol (2009) 0.84
Otx2 selectively controls the neurogenesis of specific neuronal subtypes of the ventral tegmental area and compensates En1-dependent neuronal loss and MPTP vulnerability. Dev Biol (2012) 0.83
Molecular mechanisms in the formation of the medial longitudinal fascicle. J Anat (2007) 0.83
Bmp5/7 in concert with the mid-hindbrain organizer control development of noradrenergic locus coeruleus neurons. Mol Cell Neurosci (2010) 0.82
Otx genes in neurogenesis of mesencephalic dopaminergic neurons. Dev Neurobiol (2011) 0.81
Transcriptional control of early tract formation in the embryonic chick midbrain. Development (2005) 0.81
Analysis of Lrrn1 expression and its relationship to neuromeric boundaries during chick neural development. Neural Dev (2007) 0.81
Profiling gene transcription in the developing embryo: microarray analysis on gene chips. Methods Mol Biol (2008) 0.81
Local inhibition guides the trajectory of early longitudinal tracts in the developing chick brain. Mech Dev (2004) 0.81
Chick Lrrn2, a novel downstream effector of Hoxb1 and Shh, functions in the selective targeting of rhombomere 4 motor neurons. Neural Dev (2009) 0.80
Anterior identity is established in chick epiblast by hypoblast and anterior definitive endoderm. Development (2003) 0.80
Lrrn1 is required for formation of the midbrain-hindbrain boundary and organiser through regulation of affinity differences between midbrain and hindbrain cells in chick. Dev Biol (2011) 0.80
OTX1 compensates for OTX2 requirement in regionalisation of anterior neuroectoderm. Gene Expr Patterns (2003) 0.79