Published in J Neurosci on August 15, 2002
Dissecting the age-related decline on spatial learning and memory tasks in rodent models: N-methyl-D-aspartate receptors and voltage-dependent Ca2+ channels in senescent synaptic plasticity. Prog Neurobiol (2012) 1.19
Memory deficits are associated with impaired ability to modulate neuronal excitability in middle-aged mice. Learn Mem (2009) 1.16
Effects of aging on the electrophysiological properties of layer 5 pyramidal cells in the monkey prefrontal cortex. Neuroscience (2007) 1.09
Learning and aging related changes in intrinsic neuronal excitability. Front Aging Neurosci (2010) 1.08
Calcium buffering systems and calcium signaling in aged rat basal forebrain neurons. Aging Cell (2007) 1.06
Mechanisms underlying basal and learning-related intrinsic excitability in a mouse model of Alzheimer's disease. Neurobiol Aging (2009) 1.06
The fast and slow afterhyperpolarizations are differentially modulated in hippocampal neurons by aging and learning. J Neurosci (2009) 1.05
Physiology and pathology of calcium signaling in the brain. Front Pharmacol (2012) 1.05
Redox sensitive calcium stores underlie enhanced after hyperpolarization of aged neurons: role for ryanodine receptor mediated calcium signaling. J Neurophysiol (2010) 1.00
Aging impairs electrical conduction along endothelium of resistance arteries through enhanced Ca2+-activated K+ channel activation. Arterioscler Thromb Vasc Biol (2013) 0.96
Learning to learn - intrinsic plasticity as a metaplasticity mechanism for memory formation. Neurobiol Learn Mem (2013) 0.95
Deletion of the L-type calcium channel Ca(V) 1.3 but not Ca(V) 1.2 results in a diminished sAHP in mouse CA1 pyramidal neurons. Hippocampus (2011) 0.94
Anesthesia-induced developmental neurodegeneration: the role of neuronal organelles. Front Neurol (2012) 0.94
Nonpharmacological amelioration of age-related learning deficits: the impact of hippocampal theta-triggered training. Proc Natl Acad Sci U S A (2005) 0.93
Impaired long-term potentiation and enhanced neuronal excitability in the amygdala of Ca(V)1.3 knockout mice. Neurobiol Learn Mem (2009) 0.93
Enhancement of hippocampal pyramidal cell excitability by the novel selective slow-afterhyperpolarization channel blocker 3-(triphenylmethylaminomethyl)pyridine (UCL2077). Mol Pharmacol (2006) 0.92
Susceptibility to Calcium Dysregulation during Brain Aging. Front Aging Neurosci (2009) 0.91
Altered calcium metabolism in aging CA1 hippocampal pyramidal neurons. J Neurosci (2013) 0.89
Estrogen and hippocampal plasticity in rodent models. J Alzheimers Dis (2008) 0.88
Enhanced calcium buffering in F344 rat cholinergic basal forebrain neurons is associated with age-related cognitive impairment. J Neurophysiol (2009) 0.87
Age-related increase of sI(AHP) in prefrontal pyramidal cells of monkeys: relationship to cognition. Neurobiol Aging (2010) 0.87
Plasma membrane sphingomyelin hydrolysis increases hippocampal neuron excitability by sphingosine-1-phosphate mediated mechanisms. J Neurochem (2010) 0.84
Dietary cholesterol modulates the excitability of rabbit hippocampal CA1 pyramidal neurons. Neurosci Lett (2010) 0.84
Control of IsAHP in mouse hippocampus CA1 pyramidal neurons by RyR3-mediated calcium-induced calcium release. Pflugers Arch (2007) 0.83
Estradiol reverses a calcium-related biomarker of brain aging in female rats. J Neurosci (2009) 0.83
Intrinsic Hippocampal Excitability Changes of Opposite Signs and Different Origins in CA1 and CA3 Pyramidal Neurons Underlie Aging-Related Cognitive Deficits. Front Syst Neurosci (2016) 0.81
Aging-Related Hyperexcitability in CA3 Pyramidal Neurons Is Mediated by Enhanced A-Type K+ Channel Function and Expression. J Neurosci (2015) 0.80
Preservation of motor neuron Ca2+ channel sensitivity to insulin-like growth factor-1 in brain motor cortex from senescent rat. J Physiol (2003) 0.79
Differential rescue of spatial memory deficits in aged rats by L-type voltage-dependent calcium channel and ryanodine receptor antagonism. Neuroscience (2014) 0.78
Dissecting mechanisms of brain aging by studying the intrinsic excitability of neurons. Front Aging Neurosci (2015) 0.78
IK1 channels do not contribute to the slow afterhyperpolarization in pyramidal neurons. Elife (2016) 0.78
Of mice and intrinsic excitability: genetic background affects the size of the postburst afterhyperpolarization in CA1 pyramidal neurons. J Neurophysiol (2011) 0.77
Molecular and cellular aspects of age-related cognitive decline and Alzheimer's disease. Behav Brain Res (2016) 0.76
CAMKII activation is not required for maintenance of learning-induced enhancement of neuronal excitability. PLoS One (2009) 0.76
Cellular mechanisms for altered learning in aging. Future Neurol (2010) 0.75
Oxidation of K(+) Channels in Aging and Neurodegeneration. Aging Dis (2016) 0.75
A novel mouse model of the aged brain: Over-expression of the L-type voltage-gated calcium channel CaV1.3. Behav Brain Res (2016) 0.75
CA1 pyramidal cells have diverse biophysical properties, affected by development, experience, and aging. PeerJ (2017) 0.75
BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease. Neuron (2004) 2.90
Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry. Nat Neurosci (2009) 2.15
BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice. Neurobiol Dis (2006) 1.77
Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1. Eur J Neurosci (2006) 1.69
Kalirin regulates cortical spine morphogenesis and disease-related behavioral phenotypes. Proc Natl Acad Sci U S A (2009) 1.49
Where is the trace in trace conditioning? Trends Neurosci (2008) 1.37
Watermaze learning enhances excitability of CA1 pyramidal neurons. J Neurophysiol (2003) 1.36
Single neurons in CA1 hippocampus encode trace interval duration during trace heart rate (fear) conditioning in rabbit. J Neurosci (2003) 1.33
Neural substrates underlying human delay and trace eyeblink conditioning. Proc Natl Acad Sci U S A (2008) 1.24
Vibrissa-signaled eyeblink conditioning induces somatosensory cortical plasticity. J Neurosci (2006) 1.21
GLYX-13: a monoclonal antibody-derived peptide that acts as an N-methyl-D-aspartate receptor modulator. Neuropharmacology (2005) 1.20
Learning-related postburst afterhyperpolarization reduction in CA1 pyramidal neurons is mediated by protein kinase A. Proc Natl Acad Sci U S A (2009) 1.18
Activity profiles of single neurons in caudal anterior cingulate cortex during trace eyeblink conditioning in the rabbit. J Neurophysiol (2003) 1.17
Memory deficits are associated with impaired ability to modulate neuronal excitability in middle-aged mice. Learn Mem (2009) 1.16
Cortical barrel lesions impair whisker-CS trace eyeblink conditioning. Learn Mem (2007) 1.15
The BK-mediated fAHP is modulated by learning a hippocampus-dependent task. Proc Natl Acad Sci U S A (2008) 1.15
Coupling of L-type Ca2+ channels to KV7/KCNQ channels creates a novel, activity-dependent, homeostatic intrinsic plasticity. J Neurophysiol (2008) 1.15
BMP signaling mediates effects of exercise on hippocampal neurogenesis and cognition in mice. PLoS One (2009) 1.14
Biophysical alterations of hippocampal pyramidal neurons in learning, ageing and Alzheimer's disease. Ageing Res Rev (2004) 1.10
Intrinsic neuronal excitability is reversibly altered by a single experience in fear conditioning. J Neurophysiol (2009) 1.09
Learning and aging related changes in intrinsic neuronal excitability. Front Aging Neurosci (2010) 1.08
GLYX-13, an NMDA receptor glycine site functional partial agonist enhances cognition and produces antidepressant effects without the psychotomimetic side effects of NMDA receptor antagonists. Expert Opin Investig Drugs (2013) 1.07
Exploring prefrontal cortical memory mechanisms with eyeblink conditioning. Behav Neurosci (2011) 1.07
The fast and slow afterhyperpolarizations are differentially modulated in hippocampal neurons by aging and learning. J Neurosci (2009) 1.05
The N-methyl-D-aspartate receptor modulator GLYX-13 enhances learning and memory, in young adult and learning impaired aging rats. Neurobiol Aging (2009) 1.05
fMRI of the conscious rabbit during unilateral classical eyeblink conditioning reveals bilateral cerebellar activation. J Neurosci (2003) 1.02
Learning increases intrinsic excitability of hippocampal interneurons. J Neurosci (2013) 1.02
Delay discrimination and reversal eyeblink classical conditioning in abstinent chronic alcoholics. Neuropsychology (2008) 1.01
Age-related biophysical alterations of hippocampal pyramidal neurons: implications for learning and memory. Ageing Res Rev (2002) 0.99
Blocking the BK channel impedes acquisition of trace eyeblink conditioning. Learn Mem (2009) 0.99
Slow afterhyperpolarization governs the development of NMDA receptor-dependent afterdepolarization in CA1 pyramidal neurons during synaptic stimulation. J Neurophysiol (2004) 0.98
Acute stress facilitates trace eyeblink conditioning in C57BL/6 male mice and increases the excitability of their CA1 pyramidal neurons. Learn Mem (2005) 0.95
Increasing SK2 channel activity impairs associative learning. J Neurophysiol (2012) 0.94
Autonomic dysfunction with mutations in the gene that encodes methyl-CpG-binding protein 2: insights into Rett syndrome. Auton Neurosci (2011) 0.92
Functional reorganization of a prefrontal cortical network mediating consolidation of trace eyeblink conditioning. J Neurosci (2014) 0.92
Trace eyeblink conditioning requires the hippocampus but not autophosphorylation of alphaCaMKII in mice. Learn Mem (2005) 0.92
Differential effects of alphaCaMKII mutation on hippocampal learning and changes in intrinsic neuronal excitability. Eur J Neurosci (2006) 0.91
Galantamine facilitates acquisition of hippocampus-dependent trace eyeblink conditioning in aged rabbits. Learn Mem (2004) 0.90
Enhanced neuronal excitability in rat CA1 pyramidal neurons following trace eyeblink conditioning acquisition is not due to alterations in I M. Neurobiol Learn Mem (2007) 0.89
Functional magnetic resonance imaging of delay and trace eyeblink conditioning in the primary visual cortex of the rabbit. J Neurosci (2008) 0.89
Altered calcium metabolism in aging CA1 hippocampal pyramidal neurons. J Neurosci (2013) 0.89
Functional MRI of cerebellar activity during eyeblink classical conditioning in children and adults. Hum Brain Mapp (2013) 0.88
Robust hippocampal responsivity during retrieval of consolidated associative memory. Hippocampus (2015) 0.88
Simultaneous training on two hippocampus-dependent tasks facilitates acquisition of trace eyeblink conditioning. Learn Mem (2006) 0.88
Caudate nucleus is critically involved in trace eyeblink conditioning. J Neurosci (2009) 0.88
Developmental profile of SK2 channel expression and function in CA1 neurons. Hippocampus (2011) 0.87
Synaptic strength and postsynaptically silent synapses through advanced aging in rat hippocampal CA1 pyramidal neurons. Neurobiol Aging (2008) 0.87
The effects of aging in delay and trace human eyeblink conditioning. Psychol Aging (2010) 0.86
Conditional discrimination learning in patients with bilateral medial temporal lobe amnesia. Behav Neurosci (2003) 0.85
Age-related deficits in a forebrain-dependent task, trace-eyeblink conditioning. Neurobiol Aging (2009) 0.85
A fiber optic-based system for behavioral eyeblink measurement in a MRI environment. J Neurosci Methods (2005) 0.84
Infragranular barrel cortex activity is enhanced with learning. J Neurophysiol (2012) 0.83
Evoking blinks with natural stimulation and detecting them with a noninvasive optical device: a simple, inexpensive method for use with freely moving animals. J Neurosci Methods (2008) 0.83
Trace eyeblink conditioning in abstinent alcoholic individuals: effects of complex task demands and prior conditioning. Neuropsychology (2005) 0.83
Reevaluating hippocampus-dependent learning in FVB/N mice. Behav Neurosci (2011) 0.81
Temporal discrimination learning in abstinent chronic alcoholics. Alcohol Clin Exp Res (2002) 0.80
Perirhinal and postrhinal, but not lateral entorhinal, cortices are essential for acquisition of trace eyeblink conditioning. Learn Mem (2013) 0.79
Procedural memory system supports single cue trace eyeblink conditioning in medial temporal lobe amnesia. Neuropsychology (2008) 0.78
A MRI-compatible system for whisker stimulation. J Neurosci Methods (2012) 0.78
The Development of Rapastinel (Formerly GLYX-13); A Rapid Acting and Long Lasting Antidepressant. Curr Neuropharmacol (2017) 0.78
Functional magnetic resonance imaging in the awake rabbit: a system for stimulus presentation and response detection during eyeblink conditioning. J Neurosci Methods (2003) 0.78
Caudate nucleus in retrieval of trace eyeblink conditioning after consolidation. J Neurosci (2013) 0.77
Autophosphorylation of alphaCaMKII downregulates excitability of CA1 pyramidal neurons following synaptic stimulation. Neurobiol Learn Mem (2009) 0.77
Cellular mechanisms for altered learning in aging. Future Neurol (2010) 0.75
Physiological and anatomical studies of associative learning: Convergence with learning studies of W.T. Greenough. Dev Psychobiol (2011) 0.75
Lubeluzole and conditioned learning after cerebral ischemia. Exp Brain Res (2003) 0.75