Published in Trends Immunol on September 01, 2002
Mucosal FOXP3-expressing CD4+ CD25high regulatory T cells in Helicobacter pylori-infected patients. Infect Immun (2005) 2.33
Helicobacter pylori-specific CD4+ CD25high regulatory T cells suppress memory T-cell responses to H. pylori in infected individuals. Infect Immun (2003) 2.19
Role of antibiotics and fungal microbiota in driving pulmonary allergic responses. Infect Immun (2004) 2.04
A role for CD4+CD25+ T cells in regulation of the immune response during human tuberculosis. Clin Exp Immunol (2006) 1.86
Comparative genome analysis provides insights into the evolution and adaptation of Pseudomonas syringae pv. aesculi on Aesculus hippocastanum. PLoS One (2010) 1.80
CD4-T-lymphocyte interactions with pneumolysin and pneumococci suggest a crucial protective role in the host response to pneumococcal infection. Infect Immun (2004) 1.70
The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation. Immunity (2010) 1.64
The microbiome of the lung. Transl Res (2012) 1.59
The impact of regulatory T cells on T-cell immunity following hematopoietic cell transplantation. Blood (2007) 1.57
Production of eicosanoids and other oxylipins by pathogenic eukaryotic microbes. Clin Microbiol Rev (2003) 1.45
Helminths and harmony. Gut (2004) 1.41
Assessment by flow cytometry of cytokine production in malnourished children. Clin Diagn Lab Immunol (2005) 1.30
Regulatory T cells in many flavors control asthma. Mucosal Immunol (2010) 1.28
CD73 is expressed by human regulatory T helper cells and suppresses proinflammatory cytokine production and Helicobacter felis-induced gastritis in mice. J Infect Dis (2009) 1.25
Adenylate cyclase toxin from Bordetella pertussis synergizes with lipopolysaccharide to promote innate interleukin-10 production and enhances the induction of Th2 and regulatory T cells. Infect Immun (2004) 1.25
Characterization of oral Yersinia enterocolitica infection in three different strains of inbred mice. Infect Immun (2004) 1.22
Differences in host susceptibility to disease progression in the human challenge model of Haemophilus ducreyi infection. Infect Immun (2003) 1.11
Functional characterization of human natural killer cells responding to Mycobacterium bovis bacille Calmette-Guérin. Immunology (2004) 1.11
IRAK4 kinase activity is required for Th17 differentiation and Th17-mediated disease. J Immunol (2009) 1.07
Balance of inflammatory response in stable gingivitis and progressive periodontitis lesions. Clin Exp Immunol (2006) 1.02
Reduction of retrovirus-induced immunosuppression by in vivo modulation of T cells during acute infection. J Virol (2004) 0.99
Regulating the immune system: the induction of regulatory T cells in the periphery. Arthritis Res Ther (2004) 0.98
Immunogenomics and systems biology of vaccines. Immunol Rev (2011) 0.97
Role of helminths in regulating mucosal inflammation. Springer Semin Immunopathol (2005) 0.97
Dysregulated immune profiles for skin and dendritic cells are associated with increased host susceptibility to Haemophilus ducreyi infection in human volunteers. Infect Immun (2007) 0.92
Worms and the treatment of inflammatory bowel disease: are molecules the answer? Clin Dev Immunol (2008) 0.91
Competition for antigen between Th1 and Th2 responses determines the timing of the immune response switch during Mycobaterium avium subspecies paratuberulosis infection in ruminants. PLoS Comput Biol (2014) 0.91
Identification of immunodominant B- and T-cell combined epitopes in outer membrane lipoproteins LipL32 and LipL21 of Leptospira interrogans. Clin Vaccine Immunol (2010) 0.90
Depletion of gammadelta+ T cells increases CD4+ FoxP3 (T regulatory) cell response in coxsackievirus B3-induced myocarditis. Immunology (2009) 0.89
Enhanced tolerance to autoimmune uveitis in CD200-deficient mice correlates with a pronounced Th2 switch in response to antigen challenge. J Immunol (2005) 0.88
The secretory IFN-gamma response of single CD4 memory cells after activation on different antigen presenting cell types. Clin Immunol (2007) 0.86
Regulatory T cells in mouse periapical lesions. J Endod (2009) 0.85
The role of mucosal T lymphocytes in regulating intestinal inflammation. Springer Semin Immunopathol (2005) 0.85
Systems biology applied to vaccine and immunotherapy development. BMC Syst Biol (2011) 0.85
Active immunization with myelin-derived altered peptide ligand reduces mechanical pain hypersensitivity following peripheral nerve injury. J Neuroinflammation (2015) 0.84
Cross-talk between cd1d-restricted nkt cells and γδ cells in t regulatory cell response. Virol J (2011) 0.84
Cytokine profiles amongst Sudanese patients with visceral leishmaniasis and malaria co-infections. BMC Immunol (2014) 0.83
Active and passive immunizations with Bordetella colonization factor A protect mice against respiratory challenge with Bordetella bronchiseptica. Infect Immun (2008) 0.83
Bordetella pertussis: the intersection of genomics and pathobiology. CMAJ (2005) 0.82
Cross-regulation of T regulatory-cell response after coxsackievirus B3 infection by NKT and γδ T cells in the mouse. Am J Pathol (2013) 0.81
Resistance to chlamydial lung infection is dependent on major histocompatibility complex as well as non-major histocompatibility complex determinants. Immunology (2005) 0.81
Age, gender and litter-related variation in T-lymphocyte cytokine production in young pigs. Immunology (2005) 0.81
Antigen-specific immunotherapeutic vaccine for experimental autoimmune myasthenia gravis. J Immunol (2014) 0.80
Age-related CD4(+)CD25(+)Foxp3(+) regulatory T-cell responses during Plasmodium berghei ANKA infection in mice susceptible or resistant to cerebral malaria. Korean J Parasitol (2013) 0.80
T helper cell-mediated interferon-gamma expression after human parvovirus B19 infection: persisting VP2-specific and transient VP1u-specific activity. Clin Exp Immunol (2005) 0.80
Transforming growth factor beta 1 production by CD4+ CD25+ regulatory T cells in peripheral blood mononuclear cells from healthy subjects stimulated with Leishmania guyanensis. Infect Immun (2005) 0.80
The role of regulatory T cell defects in type I diabetes and the potential of these cells for therapy. Rev Diabet Stud (2005) 0.79
Clinical Value of Assessing Cytokine Levels for the Differential Diagnosis of Bacterial Meningitis in a Pediatric Population. Medicine (Baltimore) (2016) 0.79
Potential treatment of inflammatory bowel disease: a review of helminths therapy. Gastroenterol Hepatol Bed Bench (2014) 0.79
Frequencies of CD4+ T Regulatory Cells and their CD25(high) and FoxP3(high) Subsets Augment in Peripheral Blood of Patients with Acute and Chronic Brucellosis. Osong Public Health Res Perspect (2014) 0.78
Immunologic Characterization of Cytokine Responses to Enterovirus 71 and Coxsackievirus A16 Infection in Children. Medicine (Baltimore) (2015) 0.77
Experimental murine fascioliasis derives early immune suppression with increased levels of TGF-β and IL-4. Korean J Parasitol (2012) 0.77
Pulmonary α-1,3-Glucan-Specific IgA-Secreting B Cells Suppress the Development of Cockroach Allergy. J Immunol (2016) 0.75
Rediscovering Pertussis. Front Pediatr (2016) 0.75
Microwave ablation combined with OK-432 induces Th1-type response and specific antitumor immunity in a murine model of breast cancer. J Transl Med (2017) 0.75
Cathepsin S Is Involved in Th17 Differentiation Through the Upregulation of IL-6 by Activating PAR-2 after Systemic Exposure to Lipopolysaccharide from Porphyromonas gingivalis. Front Pharmacol (2017) 0.75
B Cell Requirement for Robust Regulatory T Cell Responses to Friend Retrovirus Infection. MBio (2017) 0.75
Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity. Immunity (2009) 8.20
A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis. J Exp Med (2006) 7.87
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes. Nat Immunol (2010) 6.64
TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells. J Immunol (2006) 3.44
CD39+Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis. J Immunol (2009) 2.30
A pilot study of the immunological effects of high-dose vitamin D in healthy volunteers. Mult Scler (2012) 2.16
Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-beta. J Immunol (2008) 2.04
Caspase-1-processed cytokines IL-1beta and IL-18 promote IL-17 production by gammadelta and CD4 T cells that mediate autoimmunity. J Immunol (2011) 1.98
Toll-like receptor 4-mediated innate IL-10 activates antigen-specific regulatory T cells and confers resistance to Bordetella pertussis by inhibiting inflammatory pathology. J Immunol (2003) 1.96
Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis. Brain Behav Immun (2010) 1.93
Suppression of antitumor immunity by IL-10 and TGF-beta-producing T cells infiltrating the growing tumor: influence of tumor environment on the induction of CD4+ and CD8+ regulatory T cells. J Immunol (2006) 1.81
CD4 T helper type 1 and regulatory T cells induced against the same epitopes on the core protein in hepatitis C virus-infected persons. J Infect Dis (2002) 1.69
IL-17-producing γδ T cells and innate lymphoid cells. Eur J Immunol (2012) 1.66
Targeting regulatory T cells in cancer. Cancer Res (2011) 1.66
Hepatitis C virus non-structural protein 4 suppresses Th1 responses by stimulating IL-10 production from monocytes. Eur J Immunol (2003) 1.60
Relative contribution of Th1 and Th17 cells in adaptive immunity to Bordetella pertussis: towards the rational design of an improved acellular pertussis vaccine. PLoS Pathog (2013) 1.54
CD200 ligand receptor interaction modulates microglial activation in vivo and in vitro: a role for IL-4. J Neurosci (2007) 1.51
Inflammasome activation by adenylate cyclase toxin directs Th17 responses and protection against Bordetella pertussis. J Immunol (2010) 1.48
Influence of gastrointestinal commensal bacteria on the immune responses that mediate allergy and asthma. J Allergy Clin Immunol (2011) 1.47
Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation. J Exp Med (2013) 1.47
Depletion of NK cells results in disseminating lethal infection with Bordetella pertussis associated with a reduction of antigen-specific Th1 and enhancement of Th2, but not Tr1 cells. Eur J Immunol (2004) 1.39
Infection with a helminth parasite attenuates autoimmunity through TGF-beta-mediated suppression of Th17 and Th1 responses. J Immunol (2009) 1.39
Inhibition of ERK MAPK suppresses IL-23- and IL-1-driven IL-17 production and attenuates autoimmune disease. J Immunol (2009) 1.32
Lack of interleukin-1 receptor I (IL-1RI) protects mice from high-fat diet-induced adipose tissue inflammation coincident with improved glucose homeostasis. Diabetes (2011) 1.30
Adenylate cyclase toxin from Bordetella pertussis synergizes with lipopolysaccharide to promote innate interleukin-10 production and enhances the induction of Th2 and regulatory T cells. Infect Immun (2004) 1.25
Attenuating regulatory T cell induction by TLR agonists through inhibition of p38 MAPK signaling in dendritic cells enhances their efficacy as vaccine adjuvants and cancer immunotherapeutics. J Immunol (2008) 1.25
Activation of p38 plays a pivotal role in the inhibitory effect of lipopolysaccharide and interleukin-1 beta on long term potentiation in rat dentate gyrus. J Biol Chem (2003) 1.24
Cholera toxin promotes the induction of regulatory T cells specific for bystander antigens by modulating dendritic cell activation. J Immunol (2003) 1.24
Role of interleukin-4 in regulation of age-related inflammatory changes in the hippocampus. J Biol Chem (2004) 1.20
Autophagy regulates IL-23 secretion and innate T cell responses through effects on IL-1 secretion. J Immunol (2012) 1.19
IL-27 mediates the response to IFN-β therapy in multiple sclerosis patients by inhibiting Th17 cells. Brain Behav Immun (2011) 1.18
Stable plastid transformation in lettuce (Lactuca sativa L.). Plant Mol Biol (2005) 1.14
Dendritic cells and other innate determinants of T helper cell polarisation. Trends Immunol (2013) 1.13
Conjugated linoleic acid suppresses NF-kappa B activation and IL-12 production in dendritic cells through ERK-mediated IL-10 induction. J Immunol (2005) 1.11
Modulation of T cell and innate immune responses by retinoic Acid. J Immunol (2014) 1.10
TLR based therapeutics. Curr Opin Pharmacol (2011) 1.10
Decreased neuronal CD200 expression in IL-4-deficient mice results in increased neuroinflammation in response to lipopolysaccharide. Brain Behav Immun (2009) 1.09
Bordetella pertussis expresses a functional type III secretion system that subverts protective innate and adaptive immune responses. Infect Immun (2008) 1.09
Immunotherapy with PI3K inhibitor and Toll-like receptor agonist induces IFN-γ+IL-17+ polyfunctional T cells that mediate rejection of murine tumors. Cancer Res (2011) 1.08
Escherichia coli heat-labile enterotoxin promotes protective Th17 responses against infection by driving innate IL-1 and IL-23 production. J Immunol (2011) 1.08
Induction of regulatory cells by helminth parasites: exploitation for the treatment of inflammatory diseases. Immunol Rev (2014) 1.08
Effects of cholera toxin on innate and adaptive immunity and its application as an immunomodulatory agent. J Leukoc Biol (2004) 1.07
Regulation of interleukin-1beta by interferon-gamma is species specific, limited by suppressor of cytokine signalling 1 and influences interleukin-17 production. EMBO Rep (2010) 1.05
Staphylococcus aureus infection of mice expands a population of memory γδ T cells that are protective against subsequent infection. J Immunol (2014) 1.05
Autophagy and inflammatory diseases. Immunol Cell Biol (2013) 1.04
IFN-γ Production by amyloid β-specific Th1 cells promotes microglial activation and increases plaque burden in a mouse model of Alzheimer's disease. J Immunol (2013) 1.03
Dietary saturated fatty acids prime the NLRP3 inflammasome via TLR4 in dendritic cells-implications for diet-induced insulin resistance. Mol Nutr Food Res (2012) 1.02
A novel anti-inflammatory role of NCAM-derived mimetic peptide, FGL. Neurobiol Aging (2008) 1.00
Adenylate cycalse toxin of Bordetella pertussis inhibits TLR-induced IRF-1 and IRF-8 activation and IL-12 production and enhances IL-10 through MAPK activation in dendritic cells. J Leukoc Biol (2008) 1.00
Bordetella pertussis adenylate cyclase toxin modulates innate and adaptive immune responses: distinct roles for acylation and enzymatic activity in immunomodulation and cell death. J Immunol (2005) 1.00
Caspase-1-processed IL-1 family cytokines play a vital role in driving innate IL-17. Cytokine (2011) 0.97
Osteoarthritis-associated basic calcium phosphate crystals induce pro-inflammatory cytokines and damage-associated molecules via activation of Syk and PI3 kinase. Clin Immunol (2012) 0.97
Proinflammatory responses in the murine brain after intranasal delivery of cholera toxin: implications for the use of AB toxins as adjuvants in intranasal vaccines. J Infect Dis (2005) 0.96
Therapeutic potential of targeting IL-17. Nat Immunol (2012) 0.95
TLR, NLR Agonists, and Other Immune Modulators as Infectious Disease Vaccine Adjuvants. Curr Infect Dis Rep (2010) 0.93
Attenuation of inflammation and cellular stress-related pathways maintains insulin sensitivity in obese type I interleukin-1 receptor knockout mice on a high-fat diet. Proteomics (2009) 0.93
IL-1F5 mediates anti-inflammatory activity in the brain through induction of IL-4 following interaction with SIGIRR/TIR8. J Neurochem (2008) 0.92
CD11c+CD8alpha+ dendritic cells promote protective immunity to respiratory infection with Bordetella pertussis. J Immunol (2009) 0.92
Innate IL-10 promotes the induction of Th2 responses with plasmid DNA expressing HIV gp120. Vaccine (2005) 0.91
Respiratory infection promotes T cell infiltration and amyloid-β deposition in APP/PS1 mice. Neurobiol Aging (2013) 0.91
Improved pertussis vaccines based on adjuvants that induce cell-mediated immunity. Expert Rev Vaccines (2014) 0.91
The role of regulatory T cells in respiratory infections and allergy and asthma. Curr Allergy Asthma Rep (2010) 0.90
Innate IFN-γ promotes development of experimental autoimmune encephalomyelitis: a role for NK cells and M1 macrophages. Eur J Immunol (2014) 0.88
Gene silencing of TGF-β1 enhances antitumor immunity induced with a dendritic cell vaccine by reducing tumor-associated regulatory T cells. Cancer Immunol Immunother (2011) 0.88
Prevention of experimental colitis by parenteral administration of a pathogen-derived immunomodulatory molecule. Gut (2006) 0.87
Interleukin-1 receptor antagonist exerts agonist activity in the hippocampus independent of the interleukin-1 type I receptor. J Neuroimmunol (2003) 0.86
Alveolar macrophages contribute to respiratory tolerance by inducing FoxP3 expression in naive T cells. Am J Respir Cell Mol Biol (2013) 0.86
Inhibition of matrix metalloproteinases ameliorates blood-brain barrier disruption and neuropathological lesions caused by avirulent Semliki Forest virus infection. Vet Immunol Immunopathol (2003) 0.85
The immunoregulatory role of CD4⁺ FoxP3⁺ CD25⁻ regulatory T cells in lungs of mice infected with Bordetella pertussis. FEMS Immunol Med Microbiol (2012) 0.85
Psychological stress suppresses innate IFN-gamma production via glucocorticoid receptor activation: reversal by the anxiolytic chlordiazepoxide. Brain Behav Immun (2009) 0.84
Psychological stress increases expression of IL-10 and its homolog IL-19 via beta-adrenoceptor activation: reversal by the anxiolytic chlordiazepoxide. Brain Behav Immun (2009) 0.83
Therapeutic vaccination with dendritic cells pulsed with tumor-derived Hsp70 and a COX-2 inhibitor induces protective immunity against B16 melanoma. Vaccine (2008) 0.82
Immunology meets neuroscience--opportunities for immune intervention in neurodegenerative diseases. Brain Behav Immun (2011) 0.82
Network analysis of adipose tissue gene expression highlights altered metabolic and regulatory transcriptomic activity in high-fat-diet-fed IL-1RI knockout mice. J Nutr Biochem (2012) 0.82
IL-1beta-dependent neurological effects of the whole cell pertussis vaccine: a role for IL-1-associated signalling components in vaccine reactogenicity. J Neuroimmunol (2003) 0.81
Nitroreductase-based therapy of prostate cancer, enhanced by raising expression of heat shock protein 70, acts through increased anti-tumour immunity. Cancer Immunol Immunother (2005) 0.80
Activation of mixed glia by Abeta-specific Th1 and Th17 cells and its regulation by Th2 cells. Brain Behav Immun (2010) 0.79
Regulatory cells and the control of respiratory infection. Curr Allergy Asthma Rep (2005) 0.78
Interleukin-1 accounts for intrarenal Th17 cell activation during ureteral obstruction. Kidney Int (2011) 0.78
Long-term exposure to a high-fat diet results in the development of glucose intolerance and insulin resistance in interleukin-1 receptor I-deficient mice. Am J Physiol Endocrinol Metab (2013) 0.78
Reciprocal effects of Th1 and Treg cell inducing pathogen-associated immunomodulatory molecules on anti-tumor immunity. Cancer Immunol Immunother (2007) 0.78
Molecules of infectious agents as immunomodulatory drugs. Curr Top Med Chem (2004) 0.77
Editorial: Tregs and BCG--dangerous liaisons in TB. J Leukoc Biol (2010) 0.77
A deep rough type structure in Bordetella bronchiseptica lipopolysaccharide modulates host immune responses. Microbiol Immunol (2011) 0.76
Correction: Staphylococcus aureus Infection of mice expands a population of memory γδ T cells that are protective against subsequent infection. J Immunol (2015) 0.76
Blocking retinoic acid receptor-α enhances the efficacy of a dendritic cell vaccine against tumours by suppressing the induction of regulatory T cells. Cancer Immunol Immunother (2013) 0.76