Published in J Gastroenterol Hepatol on October 01, 2002
Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis. J Clin Invest (2008) 5.26
DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice. J Clin Invest (2008) 3.17
Chronic inflammation and cytokines in the tumor microenvironment. J Immunol Res (2014) 2.51
The AOM/DSS murine model for the study of colon carcinogenesis: From pathways to diagnosis and therapy studies. J Carcinog (2011) 2.30
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Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice. J Clin Invest (2011) 1.32
Crucial involvement of tumor-associated neutrophils in the regulation of chronic colitis-associated carcinogenesis in mice. PLoS One (2012) 1.17
Chronic epithelial NF-κB activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation. Proc Natl Acad Sci U S A (2012) 1.13
Development of colonic neoplasia in p53 deficient mice with experimental colitis induced by dextran sulphate sodium. Gut (2004) 1.08
p53 mediates TNF-induced epithelial cell apoptosis in IBD. Am J Pathol (2012) 1.07
Inducible heat shock protein 70 prevents multifocal flat dysplastic lesions and invasive tumors in an inflammatory model of colon cancer. Carcinogenesis (2008) 1.07
Modeling colitis-associated cancer with azoxymethane (AOM) and dextran sulfate sodium (DSS). J Vis Exp (2012) 1.01
A component of polysaccharide peptidoglycan complex on Lactobacillus induced an improvement of murine model of inflammatory bowel disease and colitis-associated cancer. Immunology (2008) 1.01
Adenoma formation following limited ablation of p120-catenin in the mouse intestine. PLoS One (2011) 0.98
Development of an inflammation-associated colorectal cancer model and its application for research on carcinogenesis and chemoprevention. Int J Inflam (2012) 0.96
Suppression of Tumorigenicity-14, encoding matriptase, is a critical suppressor of colitis and colitis-associated colon carcinogenesis. Oncogene (2011) 0.95
Impaired self-renewal and increased colitis and dysplastic lesions in colonic mucosa of AKR1B8-deficient mice. Clin Cancer Res (2014) 0.94
Cancer in inflammatory bowel disease: lessons from animal models. Curr Opin Gastroenterol (2012) 0.93
Inhibition of hypoxia-inducible factors limits tumor progression in a mouse model of colorectal cancer. Carcinogenesis (2014) 0.92
Selective Allosteric Inhibition of MMP9 Is Efficacious in Preclinical Models of Ulcerative Colitis and Colorectal Cancer. PLoS One (2015) 0.90
Induction of colitis and rapid development of colorectal tumors in mice deficient in the neuropeptide PACAP. Int J Cancer (2008) 0.90
IEX-1 deficiency protects against colonic cancer. Mol Cancer Res (2012) 0.87
A novel mouse model for colitis-associated colon carcinogenesis induced by 1,2-dimethylhydrazine and dextran sulfate sodium. World J Gastroenterol (2004) 0.86
Genetic and Chemical Models of Colorectal Cancer in Mice. Curr Colorectal Cancer Rep (2010) 0.85
Sporadic colon cancer murine models demonstrate the value of autoantibody detection for preclinical cancer diagnosis. Sci Rep (2013) 0.85
Urokinase-type plasminogen activator deficiency promotes neoplasmatogenesis in the colon of mice. Transl Oncol (2014) 0.82
Increase in dietary protein content exacerbates colonic inflammation and tumorigenesis in azoxymethane-induced mouse colon carcinogenesis. Nutr Res Pract (2017) 0.82
Examination of the Anti-Inflammatory, Antioxidant, and Xenobiotic-Inducing Potential of Broccoli Extract and Various Essential Oils during a Mild DSS-Induced Colitis in Rats. ISRN Gastroenterol (2013) 0.81
CITED2 is activated in ulcerative colitis and induces p53-dependent apoptosis in response to butyric acid. J Gastroenterol (2010) 0.81
Mouse models of colorectal cancer. Chin J Cancer (2011) 0.78
Tumor Necrosis Factor (TNF) and Chemokines in Colitis-Associated Cancer. Cancers (Basel) (2011) 0.77
Fibroblasts, an inconspicuous but essential player in colon cancer development and progression. World J Gastroenterol (2016) 0.76
A pilot randomised controlled trial to reduce colorectal cancer risk markers associated with B-vitamin deficiency, insulin resistance and colonic inflammation. Br J Cancer (2005) 0.76
Intestinal epithelium-specific knockout of the cytochrome P450 reductase gene exacerbates dextran sulfate sodium-induced colitis. J Pharmacol Exp Ther (2015) 0.76
Protein-bound polysaccharide-K reduces colitic tumors and improves survival of inflammatory bowel disease in vivo. Oncol Lett (2011) 0.76
Ionizing radiation, inflammation, and their interactions in colon carcinogenesis in Mlh1-deficient mice. Cancer Sci (2015) 0.75
Modulation of Colitis-associated Colon Tumorigenesis by Baicalein and Betaine. J Cancer Prev (2014) 0.75
Characterisation of colonic dysplasia-like epithelial atypia in murine colitis. World J Gastroenterol (2016) 0.75
Distribution of bone-marrow-derived endothelial and immune cells in a murine colitis-associated colorectal cancer model. PLoS One (2013) 0.75
Time course of the incidence/multiplicity and histopathological features of murine colonic dysplasia, adenoma and adenocarcinoma induced by benzo[a]pyrene and dextran sulfate sodium. J Toxicol Pathol (2015) 0.75
Stereomicroscopic features of colitis-associated tumors in mice: Evaluation of pit pattern. Oncol Lett (2017) 0.75
Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube. J Toxicol Sci (2008) 5.03
Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts. Cell (2007) 4.71
Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure. Reprod Toxicol (2007) 4.04
In vitro molecular mechanisms of bisphenol A action. Reprod Toxicol (2007) 3.69
Why public health agencies cannot depend on good laboratory practices as a criterion for selecting data: the case of bisphenol A. Environ Health Perspect (2008) 3.27
Endocrine-disrupting organotin compounds are potent inducers of adipogenesis in vertebrates. Mol Endocrinol (2006) 2.41
GlcNAcylation of histone H2B facilitates its monoubiquitination. Nature (2011) 2.14
Mechanisms of benzene-induced hematotoxicity and leukemogenicity: cDNA microarray analyses using mouse bone marrow tissue. Environ Health Perspect (2003) 1.60
EGFR genetic heterogeneity of nonsmall cell lung cancers contributing to acquired gefitinib resistance. Int J Cancer (2008) 1.55
Submucosal fibrosis and basic-fibroblast growth factor-positive neutrophils correlate with colonic stenosis in cases of ulcerative colitis. Digestion (2011) 1.47
Premature ovarian failure in androgen receptor-deficient mice. Proc Natl Acad Sci U S A (2005) 1.44
Gastric large cell neuroendocrine carcinomas: a distinct clinicopathologic entity. Am J Surg Pathol (2006) 1.43
The fatty acid profile of the erythrocyte membrane in initial-onset inflammatory bowel disease patients. Dig Dis Sci (2013) 1.41
The effect of ultraviolet functionalization of titanium on integration with bone. Biomaterials (2008) 1.38
PKA-dependent regulation of the histone lysine demethylase complex PHF2-ARID5B. Nat Cell Biol (2011) 1.36
Hypersensitivity of aryl hydrocarbon receptor-deficient mice to lipopolysaccharide-induced septic shock. Mol Cell Biol (2009) 1.32
NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs. Proc Natl Acad Sci U S A (2010) 1.32
Mouse Nkd1, a Wnt antagonist, exhibits oscillatory gene expression in the PSM under the control of Notch signaling. Mech Dev (2004) 1.27
Endoscopic resection of Peutz-Jeghers polyps throughout the small intestine at double-balloon enteroscopy without laparotomy. Gastrointest Endosc (2005) 1.24
Treatment of functional dyspepsia with antianxiety or antidepressive agents: systematic review. J Gastroenterol (2005) 1.24
High expression of L-type amino-acid transporter 1 (LAT1) in gastric carcinomas: comparison with non-cancerous lesions. Pathol Int (2011) 1.22
Hippocampal epigenetic modification at the brain-derived neurotrophic factor gene induced by an enriched environment. Hippocampus (2011) 1.20
Tbx6-mediated Notch signaling controls somite-specific Mesp2 expression. Proc Natl Acad Sci U S A (2006) 1.20
Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse. Development (2006) 1.19
Ewing's sarcoma precursors are highly enriched in embryonic osteochondrogenic progenitors. J Clin Invest (2014) 1.18
Hydrogen sulfide protects the retina from light-induced degeneration by the modulation of Ca2+ influx. J Biol Chem (2011) 1.16
Prevalence of and risk factors for low back pain among staffs in schools for physically and mentally handicapped children. Ind Health (2006) 1.16
Dose-dependent mesothelioma induction by intraperitoneal administration of multi-wall carbon nanotubes in p53 heterozygous mice. Cancer Sci (2012) 1.13
Commensal bacteria can enter colonic epithelial cells and induce proinflammatory cytokine secretion: a possible pathogenic mechanism of ulcerative colitis. J Med Microbiol (2009) 1.11
Double-balloon endoscopy for treatment of long-term abdominal discomfort due to small bowel penetration by an eel bone. Med Sci Monit (2008) 1.07
The negative regulation of Mesp2 by mouse Ripply2 is required to establish the rostro-caudal patterning within a somite. Development (2007) 1.05
Multi-center randomized controlled study to establish the standard third-line regimen for Helicobacter pylori eradication in Japan. J Gastroenterol (2013) 1.03
High prevalence of Helicobacter pylori detected by PCR in the oral cavities of periodontitis patients. J Periodontol (2003) 1.03
Current immunotherapeutic approaches in pancreatic cancer. Clin Dev Immunol (2011) 1.03
Recurrent peptic ulcers in patients following successful Helicobacter pylori eradication: a multicenter study of 4940 patients. Helicobacter (2004) 1.02
Diverse p53 alterations in ulcerative colitis-associated low-grade dysplasia: full-length gene sequencing in microdissected single crypts. J Pathol (2003) 1.01
Autocrine and paracrine roles of VEGF/VEGFR-2 and VEGF-C/VEGFR-3 signaling in angiosarcomas of the scalp and face. Hum Pathol (2009) 1.00
Clinical study of therapeutic angiogenesis by autologous peripheral blood stem cell (PBSC) transplantation in 92 patients with critically ischemic limbs. J Artif Organs (2006) 1.00
Significant increase of colonic mutated crypts correlates with age in sporadic cancer and diverticulosis cases, with higher frequency in the left- than right-side colorectum. Cancer Sci (2006) 1.00
Hepatitis B virus reactivation in a case of non-Hodgkin's lymphoma treated with chemotherapy and rituximab: necessity of prophylaxis for hepatitis B virus reactivation in rituximab therapy. Leuk Lymphoma (2004) 1.00
Combined TLR2/4-activated dendritic/tumor cell fusions induce augmented cytotoxic T lymphocytes. PLoS One (2013) 1.00
Cancer vaccine by fusions of dendritic and cancer cells. Clin Dev Immunol (2010) 1.00
Dual transneuronal tracing in the rat entorhinal-hippocampal circuit by intracerebral injection of recombinant rabies virus vectors. Front Neuroanat (2009) 1.00
The effect of UV-photofunctionalization on the time-related bioactivity of titanium and chromium-cobalt alloys. Biomaterials (2009) 0.99
Multi-walled carbon nanotubes translocate into the pleural cavity and induce visceral mesothelial proliferation in rats. Cancer Sci (2012) 0.99
Rapid and simple detection of hot spot point mutations of epidermal growth factor receptor, BRAF, and NRAS in cancers using the loop-hybrid mobility shift assay. J Mol Diagn (2006) 0.99
Ultraviolet light-mediated photofunctionalization of titanium to promote human mesenchymal stem cell migration, attachment, proliferation and differentiation. Acta Biomater (2009) 0.99
Increased esophageal sensitivity to acid and saline in patients with nonerosive gastro-esophageal reflux disease. J Clin Gastroenterol (2006) 0.96
[Treatment of tracheobronchial malignant tumors using a new high power diode contact laser (GaAlAs) system]. Gan To Kagaku Ryoho (2002) 0.96
Job stressors and job stress among teachers engaged in nursing activity. Ind Health (2007) 0.95
Differential contributions of Mesp1 and Mesp2 to the epithelialization and rostro-caudal patterning of somites. Development (2005) 0.95
The enhanced characteristics of osteoblast adhesion to photofunctionalized nanoscale TiO2 layers on biomaterials surfaces. Biomaterials (2010) 0.95
Effects of pico-to-nanometer-thin TiO2 coating on the biological properties of microroughened titanium. Biomaterials (2011) 0.95
Wilms tumor gene (WT1) peptide-based cancer vaccine combined with gemcitabine for patients with advanced pancreatic cancer. J Immunother (2014) 0.95
The oscillation of Notch activation, but not its boundary, is required for somite border formation and rostral-caudal patterning within a somite. Development (2010) 0.94
Correlations among total colonoscopic findings, clinical symptoms, and laboratory markers in ulcerative colitis. J Gastroenterol Hepatol (2008) 0.94
Double-endoscope endoscopic submucosal dissection for the treatment of early gastric cancer accompanied by an ulcer scar (with video). Gastrointest Endosc (2013) 0.94
High epithelial and stromal genetic instability of chromosome 17 in ulcerative colitis-associated carcinogenesis. Cancer Res (2003) 0.94
Regulation of tumor immunity by tumor/dendritic cell fusions. Clin Dev Immunol (2010) 0.94
Gastrointestinal stromal tumor of the stomach with a giant abscess penetrating the gastric lumen. World J Gastroenterol (2007) 0.94
Depolarization of isolated horizontal cells of fish acidifies their immediate surrounding by activating V-ATPase. J Physiol (2007) 0.94
Functional importance of evolutionally conserved Tbx6 binding sites in the presomitic mesoderm-specific enhancer of Mesp2. Development (2008) 0.94
Altered localization and expression of tight-junction proteins in a rat model with chronic acid reflux esophagitis. J Gastroenterol (2005) 0.94
Lfng regulates the synchronized oscillation of the mouse segmentation clock via trans-repression of Notch signalling. Nat Commun (2012) 0.93
Fusions between dendritic cells and whole tumor cells as anticancer vaccines. Oncoimmunology (2013) 0.93
Clinicopathologic characteristics of pancreatic neuroendocrine tumors and relation of somatostatin receptor type 2A to outcomes. Cancer (2013) 0.93
Epigenetic regulation of adipogenesis by PHF2 histone demethylase. Diabetes (2012) 0.92
Aryl hydrocarbon receptor mediates benzene-induced hematotoxicity. Toxicol Sci (2002) 0.92
Endocrine disrupter bisphenol A increases in situ estrogen production in the mouse urogenital sinus. Biol Reprod (2010) 0.92
N-3 polyunsaturated fatty acid diet therapy for patients with inflammatory bowel disease. Inflamm Bowel Dis (2010) 0.91
Neonatal exposure to low-dose 2,3,7,8-tetrachlorodibenzo-p-dioxin causes autoimmunity due to the disruption of T cell tolerance. J Immunol (2009) 0.91
Enhancement of osteoblast adhesion to UV-photofunctionalized titanium via an electrostatic mechanism. Biomaterials (2009) 0.91
Invasive behavior of ulcerative colitis-associated carcinoma is related to reduced expression of CD44 extracellular domain: comparison with sporadic colon carcinoma. Diagn Pathol (2011) 0.90
Transcriptional up-regulation of Sox9 by NF-κB in endometrial carcinoma cells, modulating cell proliferation through alteration in the p14(ARF)/p53/p21(WAF1) pathway. Am J Pathol (2012) 0.90
High expression of L-type amino acid transporter 1 (LAT1) predicts poor prognosis in pancreatic ductal adenocarcinomas. J Clin Pathol (2012) 0.90
Enhancement of bone-titanium integration profile with UV-photofunctionalized titanium in a gap healing model. Biomaterials (2009) 0.90
Synergistic effects of UV photofunctionalization and micro-nano hybrid topography on the biological properties of titanium. Biomaterials (2011) 0.90
Correlation of enhanced cell turnover with prognosis of gastrointestinal stromal tumors of the stomach: relevance of cellularity and p27kip1. Pathol Int (2006) 0.89
Squamous cell carcinoma arising from a seminal vesicular cyst: possible relationship between chronic inflammation and tumor development. Pathol Int (2002) 0.89
Peroxisome proliferator-activated receptor γ 2 mutation may cause a subset of ulcerative colitis. Pediatr Int (2010) 0.89
Iris-derived cells from adult rodents and primates adopt photoreceptor-specific phenotypes. Invest Ophthalmol Vis Sci (2005) 0.89
Tumor budding is predictive of lymphatic involvement and lymph node metastases in submucosal invasive colorectal adenocarcinomas and in non-polypoid compared with polypoid growths. Scand J Gastroenterol (2009) 0.89
Changes in the first line Helicobacter pylori eradication rates using the triple therapy-a multicenter study in the Tokyo metropolitan area (Tokyo Helicobacter pylori study group). J Gastroenterol Hepatol (2014) 0.88
Significant correlation of morphological remodeling in ulcerative colitis with disease duration and between elevated p53 and p21 expression in rectal mucosa and neoplastic development. Pathol Int (2005) 0.88
Telomere shortening in Barrett's mucosa and esophageal adenocarcinoma and its association with loss of heterozygosity. Scand J Gastroenterol (2009) 0.88
Trends of second-line eradication therapy for Helicobacter pylori in Japan: a multicenter study in the Tokyo metropolitan area. Helicobacter (2013) 0.88
Interaction of dopamine and acetylcholine with an amphiphilic resorcinarene receptor in aqueous micelle system. Bioorg Med Chem Lett (2005) 0.88
Malignant lymphoma in the ileum diagnosed by double-balloon enteroscopy. World J Gastroenterol (2007) 0.88
Association of D2-40 and MMP-1 expression with cyst formation in lung metastatic lesions of cutaneous angiosarcoma on the scalp: immunohistochemical analysis of 23 autopsy cases. Hum Pathol (2013) 0.87
The avoidance and aggregative movements of mesophyll chloroplasts in C(4) monocots in response to blue light and abscisic acid. J Exp Bot (2011) 0.87
Structure-activity-dependent regulation of cell communication by perfluorinated fatty acids using in vivo and in vitro model systems. Environ Health Perspect (2008) 0.87
Lewy body pathology in a patient with a homozygous parkin deletion. Mov Disord (2013) 0.87
Human T-cell leukemia virus type-I Tax induces expression of interleukin-6 receptor (IL-6R): Shedding of soluble IL-6R and activation of STAT3 signaling. Int J Cancer (2006) 0.87
Involvement of macrophage inflammatory protein 1alpha (MIP1alpha) in promotion of rat lung and mammary carcinogenic activity of nanoscale titanium dioxide particles administered by intra-pulmonary spraying. Carcinogenesis (2010) 0.87