Published in J Med Virol on October 01, 2002
Update on human herpesvirus 6 biology, clinical features, and therapy. Clin Microbiol Rev (2005) 2.24
Variant-specific tropism of human herpesvirus 6 in human astrocytes. J Virol (2005) 1.15
Viruses and multiple sclerosis. CNS Neurol Disord Drug Targets (2012) 1.15
Human herpes virus 6B: a possible role in epilepsy? Epilepsia (2008) 1.10
Virologic and immunologic evidence supporting an association between HHV-6 and Hashimoto's thyroiditis. PLoS Pathog (2012) 1.06
Potential triggers of MS. Results Probl Cell Differ (2010) 0.87
Possible role of human herpesvirus 6 as a trigger of autoimmune disease. ScientificWorldJournal (2013) 0.86
SJL mice infected with Acanthamoeba castellanii develop central nervous system autoimmunity through the generation of cross-reactive T cells for myelin antigens. PLoS One (2014) 0.84
Human herpesvirus 6 infection as a trigger of multiple sclerosis. Mayo Clin Proc (2010) 0.83
Role of pathogens in multiple sclerosis. Int Rev Immunol (2013) 0.82
Herpesvirus infections of the central nervous system in immunocompromised patients. Ther Adv Neurol Disord (2012) 0.81
Immunomodulation and immunosuppression by human herpesvirus 6A and 6B. Future Virol (2013) 0.80
Immune response to HHV-6 and implications for immunotherapy. Curr Opin Virol (2014) 0.78
Isolation and expansion of adult cardiac stem cells from human and murine heart. Circ Res (2004) 8.41
Mesenchymal stem cells: potential precursors for tumor stroma and targeted-delivery vehicles for anticancer agents. J Natl Cancer Inst (2004) 5.39
Lithium delays progression of amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A (2008) 5.37
Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors. Cancer Res (2002) 4.99
Dysregulated Epstein-Barr virus infection in the multiple sclerosis brain. J Exp Med (2007) 2.88
Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein. Proc Natl Acad Sci U S A (2005) 2.13
CAPS1 regulates catecholamine loading of large dense-core vesicles. Neuron (2005) 1.94
Brain white-matter volume loss and glucose hypometabolism precede the clinical symptoms of Huntington's disease. J Nucl Med (2006) 1.83
Human MRE11 is inactivated in mismatch repair-deficient cancers. EMBO Rep (2002) 1.80
Survivin, bcl-2, bax, and bcl-X gene expression in sentinel lymph nodes from melanoma patients. J Clin Oncol (2003) 1.73
Guanine nucleotide depletion triggers cell cycle arrest and apoptosis in human neuroblastoma cell lines. Int J Cancer (2004) 1.68
Antigen-activated human T lymphocytes express cell-surface NKG2D ligands via an ATM/ATR-dependent mechanism and become susceptible to autologous NK- cell lysis. Blood (2007) 1.63
Characterization and intracellular localization of the Epstein-Barr virus protein BFLF2: interactions with BFRF1 and with the nuclear lamina. J Virol (2005) 1.62
BFRF1 of Epstein-Barr virus is essential for efficient primary viral envelopment and egress. J Virol (2005) 1.59
Regulated expression of MUC1 epithelial antigen in erythropoiesis. Br J Haematol (2003) 1.56
Aspirin extrusion from human platelets through multidrug resistance protein-4-mediated transport: evidence of a reduced drug action in patients after coronary artery bypass grafting. J Am Coll Cardiol (2011) 1.55
Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis. Proc Natl Acad Sci U S A (2002) 1.54
Mutations of an intronic repeat induce impaired MRE11 expression in primary human cancer with microsatellite instability. Oncogene (2004) 1.46
Comment on: isolation and characterization of tumorigenic extrahepatic cholangiocarcinoma cells with stem cell-like properties. Int J Cancer (2011) 1.44
Prognostic significance of reverse transcriptase-polymerase chain reaction-negative sentinel nodes in malignant melanoma. Ann Surg Oncol (2003) 1.42
Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia. EMBO J (2006) 1.37
Ligand-regulated association of ErbB-4 to the transcriptional co-activator YAP65 controls transcription at the nuclear level. Exp Cell Res (2004) 1.35
microRNA profiling in Epstein-Barr virus-associated B-cell lymphoma. Nucleic Acids Res (2010) 1.32
Genome-wide significance for a modifier of age at neurological onset in Huntington's disease at 6q23-24: the HD MAPS study. BMC Med Genet (2006) 1.30
Intermittent vs continuous levodopa administration in patients with advanced Parkinson disease: a clinical and pharmacokinetic study. Arch Neurol (2005) 1.27
Tumor-associated Tn-MUC1 glycoform is internalized through the macrophage galactose-type C-type lectin and delivered to the HLA class I and II compartments in dendritic cells. Cancer Res (2007) 1.26
HE4: a new potential early biomarker for the recurrence of ovarian cancer. Tumour Biol (2010) 1.24
Subcellular localization of the BRCA1 gene product in mitotic cells. Genes Chromosomes Cancer (2002) 1.22
Notch3 and the Notch3-upregulated RNA-binding protein HuD regulate Ikaros alternative splicing. EMBO J (2007) 1.20
Autophagy and amyotrophic lateral sclerosis: The multiple roles of lithium. Autophagy (2008) 1.19
The E3 ligase Aip4/Itch ubiquitinates and targets ErbB-4 for degradation. FASEB J (2007) 1.19
Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphoma. EMBO Rep (2003) 1.18
PML-RARalpha is associated with leptin-receptor induction: the role of mesenchymal stem cell-derived adipocytes in APL cell survival. Blood (2003) 1.17
retSDR1, a short-chain retinol dehydrogenase/reductase, is retinoic acid-inducible and frequently deleted in human neuroblastoma cell lines. Cancer Res (2002) 1.17
Deletion of Epstein-Barr virus BFLF2 leads to impaired viral DNA packaging and primary egress as well as to the production of defective viral particles. J Virol (2008) 1.17
p38 MAPK activation controls the TLR3-mediated up-regulation of cytotoxicity and cytokine production in human NK cells. Blood (2004) 1.14
Suppression of dendritic cell differentiation through cytokines released by Primary Effusion Lymphoma cells. Immunol Lett (2008) 1.10
Celecoxib induces MRP-4 in lung cancer cells: therapeutic implications. J Clin Oncol (2007) 1.10
SH2-containing inositol phosphatase (SHIP-1) transiently translocates to raft domains and modulates CD16-mediated cytotoxicity in human NK cells. Blood (2002) 1.09
Expression of activated Notch3 in transgenic mice enhances generation of T regulatory cells and protects against experimental autoimmune diabetes. J Immunol (2003) 1.09
Inhibition of cell growth by EGR-1 in human primary cultures from malignant glioma. Cancer Cell Int (2004) 1.08
Primary effusion lymphoma cell death induced by bortezomib and AG 490 activates dendritic cells through CD91. PLoS One (2012) 1.07
Distinct brain volume changes correlating with clinical stage, disease progression rate, mutation size, and age at onset prediction as early biomarkers of brain atrophy in Huntington's disease. CNS Neurosci Ther (2009) 1.06
EGF- and cell-cycle-regulated STAG1/PMEPA1/ERG1.2 belongs to a conserved gene family and is overexpressed and amplified in breast and ovarian cancer. Mol Carcinog (2003) 1.06
PKC theta mediates pre-TCR signaling and contributes to Notch3-induced T-cell leukemia. Oncogene (2005) 1.06
Fine structure and biochemical mechanisms underlying nigrostriatal inclusions and cell death after proteasome inhibition. J Neurosci (2003) 1.05
Chemosensitivity profile assay of circulating cancer cells: prognostic and predictive value in epithelial tumors. Int J Cancer (2010) 1.05
Activation of Syk tyrosine kinase is required for c-Cbl-mediated ubiquitination of Fcepsilon RI and Syk in RBL cells. J Biol Chem (2002) 1.05
Vaginoplasty using autologous in vitro cultured vaginal tissue in a patient with Mayer-von-Rokitansky-Kuster-Hauser syndrome. Hum Reprod (2007) 1.04
REN: a novel, developmentally regulated gene that promotes neural cell differentiation. J Cell Biol (2002) 1.03
Pharmacological blockade of mGlu2/3 metabotropic glutamate receptors reduces cell proliferation in cultured human glioma cells. J Neurochem (2003) 1.03
Constitutively active Notch1 induces growth arrest of HPV-positive cervical cancer cells via separate signaling pathways. Exp Cell Res (2005) 1.03
Proline-rich tyrosine kinase 2 and Rac activation by chemokine and integrin receptors controls NK cell transendothelial migration. J Immunol (2003) 1.02
Current approach in the treatment of hepatocellular carcinoma. World J Gastrointest Oncol (2010) 1.01
Severe ultrastructural mitochondrial changes in lymphoblasts homozygous for Huntington disease mutation. Mech Ageing Dev (2005) 1.00
Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation. Eur J Immunol (2012) 0.99
Notch3 and canonical NF-kappaB signaling pathways cooperatively regulate Foxp3 transcription. J Immunol (2011) 0.99
Ovarian tumor marker HE4 is differently expressed during the phases of the menstrual cycle in healthy young women. Tumour Biol (2010) 0.99
Arf6: a new player in FcgammaRIIIA lymphocyte-mediated cytotoxicity. Blood (2005) 0.98
Nigrostriatal damage with 6-OHDA: validation of routinely applied procedures. Ann N Y Acad Sci (2006) 0.98
The inhibition of KCa3.1 channels activity reduces cell motility in glioblastoma derived cancer stem cells. PLoS One (2012) 0.98
UDP-glucuronosyltransferases 1A expression in human urinary bladder and colon cancer by immunohistochemistry. Oncol Rep (2005) 0.98
Human adipose-derived stromal cells for cell-based therapies in the treatment of systemic sclerosis. Cell Transplant (2013) 0.98
Role of HE4, CA72.4, and CA125 in monitoring ovarian cancer. Tumour Biol (2012) 0.98
Genotype-dependent priming to self- and xeno-cannibalism in heterozygous and homozygous lymphoblasts from patients with Huntington's disease. J Neurochem (2006) 0.97
Ovarian cancer cytoreduction induces changes in T cell population subsets reducing immunosuppression. J Cell Mol Med (2010) 0.97
A comparative analysis of serum and serum-free media for generation of clinical grade DCs. J Immunother (2007) 0.96
CIN85 regulates the ligand-dependent endocytosis of the IgE receptor: a new molecular mechanism to dampen mast cell function. J Immunol (2005) 0.96
Human herpesvirus 8 (HHV-8) inhibits monocyte differentiation into dendritic cells and impairs their immunostimulatory activity. Immunol Lett (2007) 0.95
Silencing of keratinocyte growth factor receptor restores 5-fluorouracil and tamoxifen efficacy on responsive cancer cells. PLoS One (2008) 0.95
PI5KI-dependent signals are critical regulators of the cytolytic secretory pathway. Blood (2007) 0.94
Pathogen-free, plasma-poor platelet lysate and expansion of human mesenchymal stem cells. J Transl Med (2014) 0.94
Different spectra of genomic deletions within the CCM genes between Italian and American CCM patient cohorts. Neurogenetics (2007) 0.94
Zebrafish embryo proteins induce apoptosis in human colon cancer cells (Caco2). Apoptosis (2006) 0.94
Activation of dendritic cells by tumor cell death. Oncoimmunology (2012) 0.94
Cross talk among Notch3, pre-TCR, and Tal1 in T-cell development and leukemogenesis. Blood (2005) 0.94
Early defect of transforming growth factor β1 formation in Huntington's disease. J Cell Mol Med (2011) 0.93
Juvenile Huntington's disease: does a dosage-effect pathogenic mechanism differ from the classical adult disease? Mech Ageing Dev (2005) 0.93
Hyperthermia enhances CD95-ligand gene expression in T lymphocytes. J Immunol (2005) 0.93
Protective role of group-II metabotropic glutamate receptors against nigro-striatal degeneration induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. Neuropharmacology (2003) 0.92
Recombinant tumor-associated MUC1 glycoprotein impairs the differentiation and function of dendritic cells. J Immunol (2005) 0.92
Regulation of the expression of the Epstein-Barr virus early gene BFRF1. Virology (2006) 0.91
Detection of CK19, CK20 and EGFR mRNAs in peripheral blood of carcinoma patients: correlation with clinical stage of disease. Oncol Rep (2002) 0.91
Noradrenaline in Parkinson's disease: from disease progression to current therapeutics. Curr Med Chem (2007) 0.91
Notch, a unifying target in T-cell acute lymphoblastic leukemia? Trends Mol Med (2003) 0.90
Differential response to keratinocyte growth factor receptor and epidermal growth factor receptor ligands of proliferating and differentiating intestinal epithelial cells. J Cell Physiol (2004) 0.90
15-deoxy-Delta12,14-prostaglandin J2 negatively regulates rankl gene expression in activated T lymphocytes: role of NF-kappaB and early growth response transcription factors. J Immunol (2007) 0.90