Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
In vivo imaging of amyloid deposition in Alzheimer disease using the radioligand 18F-AV-45 (florbetapir [corrected] F 18).
|
J Nucl Med
|
2010
|
2.72
|
2
|
Radiolabeled small-molecule ligands for prostate-specific membrane antigen: in vivo imaging in experimental models of prostate cancer.
|
Clin Cancer Res
|
2005
|
2.10
|
3
|
Biodistribution, tumor detection, and radiation dosimetry of 18F-DCFBC, a low-molecular-weight inhibitor of prostate-specific membrane antigen, in patients with metastatic prostate cancer.
|
J Nucl Med
|
2012
|
2.00
|
4
|
N-[N-[(S)-1,3-Dicarboxypropyl]carbamoyl]-4-[18F]fluorobenzyl-L-cysteine, [18F]DCFBC: a new imaging probe for prostate cancer.
|
Clin Cancer Res
|
2008
|
2.00
|
5
|
Initial Evaluation of [(18)F]DCFPyL for Prostate-Specific Membrane Antigen (PSMA)-Targeted PET Imaging of Prostate Cancer.
|
Mol Imaging Biol
|
2015
|
1.90
|
6
|
Persistent cognitive and dopamine transporter deficits in abstinent methamphetamine users.
|
Synapse
|
2008
|
1.66
|
7
|
11C-MCG: synthesis, uptake selectivity, and primate PET of a probe for glutamate carboxypeptidase II (NAALADase).
|
Mol Imaging
|
2003
|
1.49
|
8
|
Molecular hybrid positron emission tomography/computed tomography imaging of cardiac angiotensin II type 1 receptors.
|
J Am Coll Cardiol
|
2012
|
1.49
|
9
|
Imaging brain mu-opioid receptors in abstinent cocaine users: time course and relation to cocaine craving.
|
Biol Psychiatry
|
2005
|
1.48
|
10
|
Initial evaluation of 11C-DPA-713, a novel TSPO PET ligand, in humans.
|
J Nucl Med
|
2009
|
1.44
|
11
|
Dopamine D2 and D3 receptor occupancy in normal humans treated with the antipsychotic drug aripiprazole (OPC 14597): a study using positron emission tomography and [11C]raclopride.
|
Neuropsychopharmacology
|
2002
|
1.35
|
12
|
Positron emission tomographic studies of brain dopamine and serotonin transporters in abstinent (+/-)3,4-methylenedioxymethamphetamine ("ecstasy") users: relationship to cognitive performance.
|
Psychopharmacology (Berl)
|
2008
|
1.34
|
13
|
11C-JHU75528: a radiotracer for PET imaging of CB1 cannabinoid receptors.
|
J Nucl Med
|
2006
|
1.32
|
14
|
Quantitative PET studies of the serotonin transporter in MDMA users and controls using [11C]McN5652 and [11C]DASB.
|
Neuropsychopharmacology
|
2005
|
1.30
|
15
|
Quantification of cerebral cannabinoid receptors subtype 1 (CB1) in healthy subjects and schizophrenia by the novel PET radioligand [11C]OMAR.
|
Neuroimage
|
2010
|
1.19
|
16
|
18F-FPEB, a PET radiopharmaceutical for quantifying metabotropic glutamate 5 receptors: a first-in-human study of radiochemical safety, biokinetics, and radiation dosimetry.
|
J Nucl Med
|
2013
|
1.15
|
17
|
Differences in delta- and mu-opioid receptor blockade measured by positron emission tomography in naltrexone-treated recently abstinent alcohol-dependent subjects.
|
Neuropsychopharmacology
|
2007
|
1.14
|
18
|
Development of radioligands with optimized imaging properties for quantification of nicotinic acetylcholine receptors by positron emission tomography.
|
Life Sci
|
2009
|
1.13
|
19
|
Mu-opioid receptor binding measured by [11C]carfentanil positron emission tomography is related to craving and mood in alcohol dependence.
|
Biol Psychiatry
|
2004
|
1.12
|
20
|
Assessment of severity of coronary artery stenosis in a canine model using the PET agent 18F-fluorobenzyl triphenyl phosphonium: comparison with 99mTc-tetrofosmin.
|
J Nucl Med
|
2007
|
1.11
|
21
|
Characterization of uptake of the new PET imaging compound 18F-fluorobenzyl triphenyl phosphonium in dog myocardium.
|
J Nucl Med
|
2006
|
1.09
|
22
|
Positron emission tomography of striatal serotonin transporters in Parkinson disease.
|
Arch Neurol
|
2003
|
1.04
|
23
|
Abnormal sympathetic innervation of viable myocardium and the substrate of ventricular tachycardia after myocardial infarction.
|
J Am Coll Cardiol
|
2008
|
1.04
|
24
|
Comparison of (+)-(11)C-McN5652 and (11)C-DASB as serotonin transporter radioligands under various experimental conditions.
|
J Nucl Med
|
2002
|
1.02
|
25
|
Influence of OPRM1 Asn40Asp variant (A118G) on [11C]carfentanil binding potential: preliminary findings in human subjects.
|
Int J Neuropsychopharmacol
|
2012
|
0.99
|
26
|
Intravenous nicotine reduces cerebral glucose metabolism: a preliminary study.
|
Neuropsychopharmacology
|
2002
|
0.99
|
27
|
Brain mu-opioid receptor binding: relationship to relapse to cocaine use after monitored abstinence.
|
Psychopharmacology (Berl)
|
2008
|
0.97
|
28
|
[(11)C]-GR89696, a potent kappa opiate receptor radioligand; in vivo binding of the R and S enantiomers.
|
Nucl Med Biol
|
2002
|
0.97
|
29
|
The dopamine transporter is decreased in the striatum of subjects with restless legs syndrome.
|
Sleep
|
2011
|
0.96
|
30
|
Positron emission tomography imaging of mu- and delta-opioid receptor binding in alcohol-dependent and healthy control subjects.
|
Alcohol Clin Exp Res
|
2011
|
0.94
|
31
|
Synthesis and biodistribution of [11C]A-836339, a new potential radioligand for PET imaging of cannabinoid type 2 receptors (CB2).
|
Bioorg Med Chem
|
2010
|
0.94
|
32
|
Positron emission tomography imaging of the serotonin transporter in subjects with a history of alcoholism.
|
Biol Psychiatry
|
2004
|
0.94
|
33
|
Recent PET radioligands with optimal brain kinetics for imaging nicotinic acetylcholine receptors.
|
J Labelled Comp Radiopharm
|
2013
|
0.93
|
34
|
Regional mu-opioid receptor binding in insular cortex is decreased in bulimia nervosa and correlates inversely with fasting behavior.
|
J Nucl Med
|
2005
|
0.92
|
35
|
Detection and quantification of the evolution dynamics of apoptosis using the PET voltage sensor 18F-fluorobenzyl triphenyl phosphonium.
|
J Nucl Med
|
2009
|
0.92
|
36
|
Radionuclide imaging of angiotensin II type 1 receptor upregulation after myocardial ischemia-reperfusion injury.
|
J Nucl Med
|
2010
|
0.91
|
37
|
PET Imaging of nicotinic acetylcholine receptors in baboons with 18F-AZAN, a radioligand with improved brain kinetics.
|
J Nucl Med
|
2011
|
0.89
|
38
|
Discovery of (-)-7-methyl-2-exo-[3'-(6-[18F]fluoropyridin-2-yl)-5'-pyridinyl]-7-azabicyclo[2.2.1]heptane, a radiolabeled antagonist for cerebral nicotinic acetylcholine receptor (alpha4beta2-nAChR) with optimal positron emission tomography imaging properties.
|
J Med Chem
|
2008
|
0.89
|
39
|
Synthesis and in vivo evaluation of a new PET radioligand for studying sigma-2 receptors.
|
Bioorg Med Chem
|
2005
|
0.89
|
40
|
18F-ASEM, a radiolabeled antagonist for imaging the α7-nicotinic acetylcholine receptor with PET.
|
J Nucl Med
|
2014
|
0.88
|
41
|
Increased synaptic dopamine in the putamen in restless legs syndrome.
|
Sleep
|
2013
|
0.87
|
42
|
A novel radioligand for imaging the AT1 angiotensin receptor with PET.
|
Nucl Med Biol
|
2004
|
0.86
|
43
|
Derivatives of dibenzothiophene for positron emission tomography imaging of α7-nicotinic acetylcholine receptors.
|
J Med Chem
|
2013
|
0.86
|
44
|
Glycine transporter type 1 occupancy by bitopertin: a positron emission tomography study in healthy volunteers.
|
Neuropsychopharmacology
|
2012
|
0.86
|
45
|
Derivatives of (-)-7-methyl-2-(5-(pyridinyl)pyridin-3-yl)-7-azabicyclo[2.2.1]heptane are potential ligands for positron emission tomography imaging of extrathalamic nicotinic acetylcholine receptors.
|
J Med Chem
|
2007
|
0.86
|
46
|
Synthesis and biodistribution of [11C]adenosine 5'-monophosphate ([11C]AMP).
|
Mol Imaging Biol
|
2005
|
0.86
|
47
|
Pre-clinical characterization of [11C]R05013853 as a novel radiotracer for imaging of the glycine transporter type 1 by positron emission tomography.
|
Neuroimage
|
2011
|
0.85
|
48
|
5-(5-(6-[(11)C]methyl-3,6-diazabicyclo[3.2.0]heptan-3-yl)pyridin-2-yl)-1H-indole as a potential PET radioligand for imaging cerebral α7-nAChR in mice.
|
Bioorg Med Chem
|
2012
|
0.85
|
49
|
Synthesis and biodistribution of radiolabeled alpha 7 nicotinic acetylcholine receptor ligands.
|
J Nucl Med
|
2005
|
0.85
|
50
|
Human brain imaging of α7 nAChR with [(18)F]ASEM: a new PET radiotracer for neuropsychiatry and determination of drug occupancy.
|
Mol Imaging Biol
|
2014
|
0.84
|
51
|
In vivo investigation of estrogen regulation of adrenal and renal angiotensin (AT1) receptor expression by PET.
|
J Nucl Med
|
2004
|
0.84
|
52
|
PET Imaging of the AT1 receptor with [11C]KR31173.
|
Nucl Med Biol
|
2006
|
0.83
|
53
|
New synthesis and evaluation of enantiomers of 7-methyl-2-exo-(3'-iodo-5'-pyridinyl)-7-azabicyclo[2.2.1]heptane as stereoselective ligands for PET imaging of nicotinic acetylcholine receptors.
|
Bioorg Med Chem Lett
|
2008
|
0.83
|
54
|
Synthesis and evaluation of new radioligands [(11)C]A-833834 and [(11)C]A-752274 for positron-emission tomography of α7-nicotinic acetylcholine receptors.
|
Nucl Med Biol
|
2013
|
0.83
|
55
|
The competition between endogenous dopamine and radioligands for specific binding to dopamine receptors.
|
Ann N Y Acad Sci
|
2002
|
0.82
|
56
|
PET imaging of high-affinity α4β2 nicotinic acetylcholine receptors in humans with 18F-AZAN, a radioligand with optimal brain kinetics.
|
J Nucl Med
|
2013
|
0.82
|
57
|
Synthesis and biodistribution of (11)C-GW7845, a positron-emitting agonist for peroxisome proliferator-activated receptor-{gamma}.
|
J Nucl Med
|
2005
|
0.82
|
58
|
Stable delineation of the ischemic area by the PET perfusion tracer 18F-fluorobenzyl triphenyl phosphonium after transient coronary occlusion.
|
J Nucl Med
|
2011
|
0.82
|
59
|
Microwave-assisted radiosynthesis of [(18) F]ASEM, a radiolabeled α7-nicotinic acetylcholine receptor antagonist.
|
J Labelled Comp Radiopharm
|
2015
|
0.82
|
60
|
Discrepant uptake of the radiolabeled norepinephrine analogues hydroxyephedrine (HED) and metaiodobenzylguanidine (MIBG) in rat hearts.
|
Eur J Nucl Med Mol Imaging
|
2013
|
0.82
|
61
|
Characterization of [11C]RO5013853, a novel PET tracer for the glycine transporter type 1 (GlyT1) in humans.
|
Neuroimage
|
2011
|
0.81
|
62
|
PET imaging of human cardiac opioid receptors.
|
Eur J Nucl Med Mol Imaging
|
2002
|
0.81
|
63
|
A microwave radiosynthesis of the 4-[18F]-fluorobenzyltriphenylphosphonium ion.
|
J Labelled Comp Radiopharm
|
2014
|
0.81
|
64
|
6-Chloro-3-(((1-[11C]methyl)-2-(S)-pyrrolidinyl)methoxy)-5-(2-fluoropyridin-4-yl)pyridine ([11C]JHU85270), a potent ligand for nicotinic acetylcholine receptor imaging by positron emission tomography.
|
Appl Radiat Isot
|
2007
|
0.80
|
65
|
Benzodiazepine binding site occupancy by the novel GABAA receptor subtype-selective drug 7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine (TPA023) in rats, primates, and humans.
|
J Pharmacol Exp Ther
|
2009
|
0.79
|
66
|
Radiochemical synthesis and in vivo evaluation of [18F]AZ11637326: an agonist probe for the α7 nicotinic acetylcholine receptor.
|
Nucl Med Biol
|
2013
|
0.79
|
67
|
Brain glucose metabolism in Rett Syndrome.
|
Pediatr Neurol
|
2002
|
0.79
|
68
|
Dissociative changes in the Bmax and KD of dopamine D2/D3 receptors with aging observed in functional subdivisions of the striatum: a revisit with an improved data analysis method.
|
J Nucl Med
|
2012
|
0.78
|
69
|
Synthesis and biological evaluation of novel carbon-11 labeled pyridyl ethers: candidate ligands for in vivo imaging of alpha4beta2 nicotinic acetylcholine receptors (alpha4beta2-nAChRs) in the brain with positron emission tomography.
|
Bioorg Med Chem
|
2009
|
0.78
|
70
|
In vivo PET imaging of cardiac presynaptic sympathoneuronal mechanisms in the rat.
|
J Nucl Med
|
2008
|
0.78
|
71
|
Targeting of endothelin receptors in the healthy and infarcted rat heart using the PET tracer 18F-FBzBMS.
|
J Nucl Med
|
2013
|
0.77
|
72
|
N-(4-cyanotetrahydro-2H-pyran-4-yl) and N-(1-cyanocyclohexyl) derivatives of 1,5-diarylpyrazole-3-carboxamides showing high affinity for 18 kDa translocator protein and/or cannabinoid receptors.
|
J Med Chem
|
2011
|
0.77
|
73
|
Carbon-11 labeled radioligands for imaging brain cannabinoid receptors.
|
Nucl Med Biol
|
2002
|
0.77
|
74
|
Synthesis and in vivo evaluation of (S)-6-(4-fluorophenoxy)-3-((1-[11C]methylpiperidin-3-yl)methyl)-2-o-tolylquinazolin-4(3H)-one, a potential PET tracer for growth hormone secretagogue receptor (GHSR).
|
Bioorg Med Chem
|
2011
|
0.76
|
75
|
Radiosynthesis and mouse brain distribution studies of [11C] CP-126,998: a PET ligand for in vivo study of acetylcholinesterase.
|
Nucl Med Biol
|
2002
|
0.76
|
76
|
Pharmacological evaluation of a Br-76 analog of epibatidine: a potent ligand for studying brain nicotinic acetylcholine receptors.
|
Synapse
|
2002
|
0.76
|
77
|
Dose-dependent, saturable occupancy of the metabotropic glutamate subtype 5 receptor by fenobam as measured with [(11) C]ABP688 PET imaging.
|
Synapse
|
2014
|
0.75
|
78
|
Synthesis and in vivo evaluation of novel PET radioligands for imaging the endothelin-A receptor.
|
J Nucl Med
|
2008
|
0.75
|
79
|
Quantitative Multi-modal Brain Autoradiography of Glutamatergic, Dopaminergic, Cannabinoid, and Nicotinic Receptors in Mutant Disrupted-In-Schizophrenia-1 (DISC1) Mice.
|
Mol Imaging Biol
|
2015
|
0.75
|
80
|
Analogs of JHU75528, a PET ligand for imaging of cerebral cannabinoid receptors (CB1): development of ligands with optimized lipophilicity and binding affinity.
|
Eur J Med Chem
|
2008
|
0.75
|
81
|
Current topics in the development of radioligands for positron-emission tomography imaging.
|
Curr Top Med Chem
|
2010
|
0.75
|
82
|
Recent advances in the medicinal radiochemistry of radioligands for cerebral in vivo imaging.
|
Curr Top Med Chem
|
2010
|
0.75
|
83
|
Synthesis and in vivo evaluation of a PET radioligand for imaging the endothelin-A receptor.
|
Nucl Med Biol
|
2006
|
0.75
|
84
|
Quantitative positron emission tomography studies of the serotonin transporter in humans previously treated with the appetite suppressants fenfluramine or dexfenfluramine.
|
Mol Imaging Biol
|
2007
|
0.75
|
85
|
Identification of Three Novel Radiotracers for Imaging Aggregated Tau in Alzheimer's Disease with Positron Emission Tomography.
|
J Med Chem
|
2017
|
0.75
|