PubRank

Ton N M Schumacher

Author PubWeight™ 85.04‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Design and use of conditional MHC class I ligands. Nat Med 2006 3.01
2 Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy. Nat Med 2010 2.92
3 Heterogeneous differentiation patterns of individual CD8+ T cells. Science 2013 2.54
4 Generation of peptide-MHC class I complexes through UV-mediated ligand exchange. Nat Protoc 2006 2.47
5 Antigen bias in T cell cross-priming. Science 2004 1.82
6 TIL therapy broadens the tumor-reactive CD8(+) T cell compartment in melanoma patients. Oncoimmunology 2012 1.78
7 The cancer antigenome. EMBO J 2012 1.78
8 Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7. Proc Natl Acad Sci U S A 2008 1.77
9 Recruitment of antigen-specific CD8+ T cells in response to infection is markedly efficient. Science 2009 1.70
10 A rapid and potent DNA vaccination strategy defined by in vivo monitoring of antigen expression. Nat Med 2005 1.61
11 One naive T cell, multiple fates in CD8+ T cell differentiation. J Exp Med 2010 1.55
12 In situ dissection of the graft-versus-host activities of cytotoxic T cells specific for minor histocompatibility antigens. Nat Med 2002 1.54
13 Dissecting T cell lineage relationships by cellular barcoding. J Exp Med 2008 1.53
14 Adoptive transfer of T-cell immunity. Trends Immunol 2002 1.50
15 Tumor rejection induced by CD70-mediated quantitative and qualitative effects on effector CD8+ T cell formation. J Exp Med 2004 1.46
16 Differential kinetics of antigen-specific CD4+ and CD8+ T cell responses in the regression of retrovirus-induced sarcomas. J Immunol 2002 1.46
17 Lactate dehydrogenase as a selection criterion for ipilimumab treatment in metastatic melanoma. Cancer Immunol Immunother 2014 1.42
18 High-throughput identification of antigen-specific TCRs by TCR gene capture. Nat Med 2013 1.40
19 Single-cell perforin and granzyme expression reveals the anatomical localization of effector CD8+ T cells in influenza virus-infected mice. Proc Natl Acad Sci U S A 2003 1.39
20 Evidence for a TCR affinity threshold delimiting maximal CD8 T cell function. J Immunol 2010 1.33
21 Selecting highly affine and well-expressed TCRs for gene therapy of melanoma. Blood 2007 1.25
22 T-cell receptor gene therapy of established tumors in a murine melanoma model. J Immunother 2008 1.24
23 MHC multimer technology: current status and future prospects. Curr Opin Immunol 2005 1.24
24 Intravital imaging of fluorescent markers and FRET probes by DNA tattooing. BMC Biotechnol 2007 1.19
25 Generation of T cell help through a MHC class I-restricted TCR. J Immunol 2006 1.15
26 Preclinical development of T cell receptor gene therapy. Curr Opin Immunol 2009 1.14
27 Prospects and limitations of T cell receptor gene therapy. Curr Gene Ther 2011 1.11
28 Balancing between antitumor efficacy and autoimmune pathology in T-cell-mediated targeting of carcinoembryonic antigen. Cancer Res 2008 1.11
29 Functional human antigen-specific T cells produced in vitro using retroviral T cell receptor transfer into hematopoietic progenitors. J Immunol 2007 1.10
30 TCR gene therapy of spontaneous prostate carcinoma requires in vivo T cell activation. J Immunol 2008 1.08
31 The immune system strikes back: cellular immune responses against indoleamine 2,3-dioxygenase. PLoS One 2009 1.07
32 Targeting self-antigens through allogeneic TCR gene transfer. Blood 2006 1.06
33 Ipilimumab-induced sarcoidosis in a patient with metastatic melanoma undergoing complete remission. J Clin Oncol 2011 1.04
34 High-throughput identification of potential minor histocompatibility antigens by MHC tetramer-based screening: feasibility and limitations. PLoS One 2011 1.03
35 Requirements for effective antitumor responses of TCR transduced T cells. J Immunol 2008 1.02
36 CD8+ T cell tolerance and cancer immunotherapy. J Immunother 2003 1.01
37 Temporal effects of gamma interferon deficiency on the course of Friend retrovirus infection in mice. J Virol 2002 1.01
38 Specificity and affinity motifs for Grb2 SH2-ligand interactions. Proc Natl Acad Sci U S A 2002 1.01
39 The descent of memory T cells. Ann N Y Acad Sci 2011 1.01
40 High-throughput T-cell epitope discovery through MHC peptide exchange. Methods Mol Biol 2009 1.00
41 TCR repertoires of intratumoral T-cell subsets. Immunol Rev 2014 1.00
42 Direct ex vivo detection of HLA-DR3-restricted cytomegalovirus- and Mycobacterium tuberculosis-specific CD4+ T cells. Hum Immunol 2005 0.99
43 TCR transgenes and transgene cassettes for TCR gene therapy: status in 2008. Cancer Immunol Immunother 2009 0.99
44 Discovering naturally processed antigenic determinants that confer protective T cell immunity. J Clin Invest 2013 0.99
45 Analysis of autoreactive CD4 T cells in experimental autoimmune encephalomyelitis after primary and secondary challenge using MHC class II tetramers. J Immunol 2004 0.97
46 Prospects and limitations of T cell receptor gene therapy. Curr Gene Ther 2005 0.97
47 In vivo antigen stability affects DNA vaccine immunogenicity. J Immunol 2007 0.96
48 Class I major histocompatibility complexes loaded by a periodate trigger. J Am Chem Soc 2009 0.95
49 An inducible caspase 9 safety switch can halt cell therapy-induced autoimmune disease. J Immunol 2008 0.94
50 Improved HIV-1 specific T-cell responses by short-interval DNA tattooing as compared to intramuscular immunization in non-human primates. Vaccine 2008 0.94
51 Generation of peptide MHC class I monomers and multimers through ligand exchange. Curr Protoc Immunol 2009 0.92
52 Enhanced immunogenicity of HPV 16 E7 fusion proteins in DNA vaccination. Virology 2002 0.90
53 T-cell receptor gene therapy: critical parameters for clinical success. J Invest Dermatol 2011 0.90
54 Blockade of TGF-β signaling greatly enhances the efficacy of TCR gene therapy of cancer. J Immunol 2013 0.89
55 The impact of self-tolerance on the polyclonal CD8+ T cell repertoire. J Immunol 2004 0.88
56 UV-induced ligand exchange in MHC class I protein crystals. J Am Chem Soc 2009 0.88
57 Effective postexposure treatment of retrovirus-induced disease with immunostimulatory DNA containing CpG motifs. J Virol 2002 0.87
58 Human telomerase reverse transcriptase-transduced human cytotoxic T cells suppress the growth of human melanoma in immunodeficient mice. Cancer Res 2004 0.87
59 Can the low-avidity self-specific T cell repertoire be exploited for tumor rejection? J Immunol 2002 0.86
60 Mixed functional characteristics correlating with TCR-ligand koff -rate of MHC-tetramer reactive T cells within the naive T-cell repertoire. Eur J Immunol 2013 0.84
61 Long-term functionality of TCR-transduced T cells in vivo. J Immunol 2008 0.84
62 Immunological tumor destruction in a murine melanoma model by targeted LTalpha independent of secondary lymphoid tissue. Cancer Immunol Immunother 2007 0.83
63 Optimizing the efficacy of epitope-directed DNA vaccination. J Immunol 2002 0.82
64 Technologies for MHC class I immunoproteomics. J Proteomics 2010 0.81
65 HLA micropolymorphisms strongly affect peptide-MHC multimer-based monitoring of antigen-specific CD8+ T cell responses. J Immunol 2013 0.81
66 Immunotherapeutic strategies: the melanoma example. Immunotherapy 2009 0.79
67 Skewing the T-cell repertoire by combined DNA vaccination, host conditioning, and adoptive transfer. Cancer Res 2008 0.78
68 Development of a hypersensitive periodate-cleavable amino acid that is methionine- and disulfide-compatible and its application in MHC exchange reagents for T cell characterisation. Chembiochem 2013 0.78
69 Effective graft depletion of MiHAg T-cell specificities and consequences for graft-versus-host disease. Blood 2007 0.78
70 Vaccine leads to memory loss. Nat Med 2007 0.77
71 Intradermal vaccination by DNA tattooing. Methods Mol Biol 2014 0.77
72 Microbead-assisted retroviral transduction for clinical application. Hum Gene Ther 2010 0.76
73 Tumors hijack fetal enzyme, escape killer T cells. Nat Med 2003 0.75
74 Corrigendum: High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4(+) T cells in human melanoma. Nat Med 2016 0.75
75 Gene transfer of MHC-restricted receptors. Methods Mol Med 2005 0.75
76 Correction: Preventing tumor escape by targeting a post-proteasomal trimming independent epitope. J Exp Med 2017 0.75