Martha L Ludwig

Author PubWeight™ 13.20‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Structures of the N-terminal modules imply large domain motions during catalysis by methionine synthase. Proc Natl Acad Sci U S A 2004 1.62
2 Domain alternation switches B(12)-dependent methionine synthase to the activation conformation. Nat Struct Biol 2002 1.47
3 Cobalamin-independent methionine synthase (MetE): a face-to-face double barrel that evolved by gene duplication. PLoS Biol 2004 1.35
4 Factors modulating conformational equilibria in large modular proteins: a case study with cobalamin-dependent methionine synthase. Proc Natl Acad Sci U S A 2003 1.27
5 Betaine-homocysteine methyltransferase: zinc in a distorted barrel. Structure 2002 1.26
6 Glycerol-3-phosphate cytidylyltransferase. Structural changes induced by binding of CDP-glycerol and the role of lysine residues in catalysis. J Biol Chem 2003 1.00
7 Dissecting the catalytic mechanism of betaine-homocysteine S-methyltransferase by use of intrinsic tryptophan fluorescence and site-directed mutagenesis. Biochemistry 2004 1.00
8 Metal active site elasticity linked to activation of homocysteine in methionine synthases. Proc Natl Acad Sci U S A 2008 0.94
9 A disulfide-stabilized conformer of methionine synthase reveals an unexpected role for the histidine ligand of the cobalamin cofactor. Proc Natl Acad Sci U S A 2008 0.91
10 Structures of NADH and CH3-H4folate complexes of Escherichia coli methylenetetrahydrofolate reductase reveal a spartan strategy for a ping-pong reaction. Biochemistry 2005 0.90
11 Structural perturbations in the Ala --> Val polymorphism of methylenetetrahydrofolate reductase: how binding of folates may protect against inactivation. Biochemistry 2006 0.90
12 Effector regulation in a monomeric enzyme. Nat Struct Biol 2002 0.79