Published in Ann Thorac Surg on September 01, 2002
Adenosine receptors as therapeutic targets. Nat Rev Drug Discov (2006) 6.15
Selective adenosine A2A receptor agonists and antagonists protect against spinal cord injury through peripheral and central effects. J Neuroinflammation (2011) 0.91
Targeting the hypoxia-adenosinergic signaling pathway to improve the adoptive immunotherapy of cancer. J Mol Med (Berl) (2013) 0.87
Timing of adenosine 2A receptor stimulation relative to reperfusion has differential effects on infarct size and cardiac function as assessed in mice by MRI. Am J Physiol Heart Circ Physiol (2008) 0.84
Maximizing neuroprotection: where do we stand? Ther Clin Risk Manag (2012) 0.80
Early adenosine receptor activation ameliorates spinal cord reperfusion injury. J Cardiovasc Med (Hagerstown) (2008) 0.79
Human monocyte recognition of adenosine-based cyclic dinucleotides unveils the A2a Gαs protein-coupled receptor tonic inhibition of mitochondrially induced cell death. Mol Cell Biol (2014) 0.77
Adenosine 2A receptor modulates inflammation and phenotype in experimental abdominal aortic aneurysms. FASEB J (2013) 0.76
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J Exp Med (2007) 10.00
Surgical treatment of moderate ischemic mitral regurgitation. N Engl J Med (2014) 7.23
Mitral-valve repair versus replacement for severe ischemic mitral regurgitation. N Engl J Med (2013) 6.21
Adenosine receptors: therapeutic aspects for inflammatory and immune diseases. Nat Rev Drug Discov (2008) 4.76
International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and classification of adenosine receptors--an update. Pharmacol Rev (2011) 4.16
Acute kidney injury is associated with increased long-term mortality after cardiothoracic surgery. Circulation (2009) 3.75
Blood transfusion and infection after cardiac surgery. Ann Thorac Surg (2013) 3.35
Two-Year Outcomes of Surgical Treatment of Severe Ischemic Mitral Regurgitation. N Engl J Med (2015) 3.11
Central cannulation is safe in acute aortic dissection repair. J Thorac Cardiovasc Surg (2006) 2.98
The role of methylene blue in serotonin syndrome following cardiac transplantation: a case report and review of the literature. J Thorac Cardiovasc Surg (2012) 2.86
A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells. Blood (2007) 2.69
Adenosine A2A receptor activation reduces hepatic ischemia reperfusion injury by inhibiting CD1d-dependent NKT cell activation. J Exp Med (2006) 2.62
Surgical ventricular restoration in the treatment of congestive heart failure due to post-infarction ventricular dilation. J Am Coll Cardiol (2004) 2.62
Cutting edge: Critical role for A2A adenosine receptors in the T cell-mediated regulation of colitis. J Immunol (2006) 2.37
A2A adenosine receptor induction inhibits IFN-gamma production in murine CD4+ T cells. J Immunol (2005) 2.37
Compartmentalization of neutrophils in the kidney and lung following acute ischemic kidney injury. Kidney Int (2009) 2.30
Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: role of macrophages. Am J Physiol Renal Physiol (2004) 2.27
Early outcomes using the Florida sleeve repair for correction of aortic insufficiency due to root aneurysms. Ann Thorac Surg (2009) 2.24
Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: the role of CD4+ T cells and IFN-gamma. J Immunol (2006) 2.22
Renal protection from ischemia mediated by A2A adenosine receptors on bone marrow-derived cells. J Clin Invest (2003) 2.22
RIFLE criteria for acute kidney injury in aortic arch surgery. J Thorac Cardiovasc Surg (2007) 2.17
Analysis of the US Food and Drug Administration Manufacturer and User Facility Device Experience database for adverse events involving Amplatzer septal occluder devices and comparison with the Society of Thoracic Surgery congenital cardiac surgery database. J Thorac Cardiovasc Surg (2009) 2.17
Predicted risk of mortality models: surgeons need to understand limitations of the University HealthSystem Consortium models. J Am Coll Surg (2009) 2.10
Does the Society of Thoracic Surgeons risk score accurately predict operative mortality for patients with pulmonary hypertension? J Thorac Cardiovasc Surg (2012) 2.09
Dendritic cells tolerized with adenosine A₂AR agonist attenuate acute kidney injury. J Clin Invest (2012) 2.00
2-Aminothiophene-3-carboxylates and carboxamides as adenosine A1 receptor allosteric enhancers. Bioorg Med Chem (2005) 1.94
Myocardial infarct-sparing effect of adenosine A2A receptor activation is due to its action on CD4+ T lymphocytes. Circulation (2006) 1.94
Ischemia-reperfusion injury after lung transplantation increases risk of late bronchiolitis obliterans syndrome. Ann Thorac Surg (2002) 1.91
Alveolar macrophage activation is a key initiation signal for acute lung ischemia-reperfusion injury. Am J Physiol Lung Cell Mol Physiol (2006) 1.80
Infarct-sparing effect of A2A-adenosine receptor activation is due primarily to its action on lymphocytes. Circulation (2005) 1.75
Intrathoracic vacuum-assisted management of persistent and infected pleural spaces. Ann Thorac Surg (2010) 1.74
Ex vivo rehabilitation of non-heart-beating donor lungs in preclinical porcine model: delayed perfusion results in superior lung function. J Thorac Cardiovasc Surg (2012) 1.73
NKT cells mediate pulmonary inflammation and dysfunction in murine sickle cell disease through production of IFN-gamma and CXCR3 chemokines. Blood (2009) 1.69
Primary payer status affects mortality for major surgical operations. Ann Surg (2010) 1.69
Activation of A2A adenosine receptor attenuates intestinal inflammation in animal models of inflammatory bowel disease. Gastroenterology (2005) 1.66
Do you need to clamp a patent left internal thoracic artery-left anterior descending graft in reoperative cardiac surgery? Ann Thorac Surg (2009) 1.63
Therapeutic anti-inflammatory effects of myeloid cell adenosine receptor A2a stimulation in lipopolysaccharide-induced lung injury. J Immunol (2007) 1.62
Lipopolysaccharide rapidly modifies adenosine receptor transcripts in murine and human macrophages: role of NF-kappaB in A(2A) adenosine receptor induction. Biochem J (2005) 1.60
Extracellular adenosine regulates naive T cell development and peripheral maintenance. J Exp Med (2013) 1.57
Adenosine A2A receptors induced on iNKT and NK cells reduce pulmonary inflammation and injury in mice with sickle cell disease. Blood (2010) 1.56
Protection from ischemic liver injury by activation of A2A adenosine receptors during reperfusion: inhibition of chemokine induction. Am J Physiol Gastrointest Liver Physiol (2004) 1.55
Cost-analysis of percutaneous pulmonary valve implantation compared to surgical pulmonary valve replacement. Catheter Cardiovasc Interv (2013) 1.53
Smooth muscle phenotypic modulation is an early event in aortic aneurysms. J Thorac Cardiovasc Surg (2009) 1.53
Adenosine A2A receptor activation attenuates inflammation and injury in diabetic nephropathy. Am J Physiol Renal Physiol (2005) 1.52
High spatial resolution magnetic resonance imaging of cystic adventitial disease of the popliteal artery. J Vasc Surg (2010) 1.52
Is mitral valve repair superior to replacement in elderly patients? Ann Thorac Surg (2008) 1.52
Percutaneous intentional extraluminal recanalization in patients with chronic critical limb ischemia. Radiology (2004) 1.51
Sleep deprivation does not affect operative results in cardiac surgery. Ann Thorac Surg (2004) 1.51
NF-κB is activated in CD4+ iNKT cells by sickle cell disease and mediates rapid induction of adenosine A2A receptors. PLoS One (2013) 1.50
Coronary artery bypass with ventricular restoration is superior to coronary artery bypass alone in patients with ischemic cardiomyopathy. J Thorac Cardiovasc Surg (2004) 1.50
A2B adenosine receptor gene deletion attenuates murine colitis. Gastroenterology (2008) 1.49
Proinflammatory response of alveolar epithelial cells is enhanced by alveolar macrophage-produced TNF-alpha during pulmonary ischemia-reperfusion injury. Am J Physiol Lung Cell Mol Physiol (2007) 1.48
Is off-pump coronary artery bypass grafting superior to conventional bypass in octogenarians? J Thorac Cardiovasc Surg (2010) 1.47
Blood product conservation is associated with improved outcomes and reduced costs after cardiac surgery. J Thorac Cardiovasc Surg (2013) 1.45
Comparison of systemic and retrograde delivery of adenosine A2A agonist for attenuation of spinal cord injury after thoracic aortic cross-clamping. Ann Thorac Surg (2006) 1.44
Additive protection against lung ischemia-reperfusion injury by adenosine A2A receptor activation before procurement and during reperfusion. J Thorac Cardiovasc Surg (2007) 1.42
Effect of ABO-incompatible listing on infant heart transplant waitlist outcomes: analysis of the United Network for Organ Sharing (UNOS) database. J Heart Lung Transplant (2009) 1.42
Replacement of the proximal aorta adds no further risk to aortic valve procedures. Ann Thorac Surg (2007) 1.40
Mitral stenosis caused by an amplatzer occluder device used to treat a paravalvular leak. Ann Thorac Surg (2012) 1.39
The A2B adenosine receptor impairs the maturation and immunogenicity of dendritic cells. J Immunol (2009) 1.39
Human A(2A) adenosine receptors: high-affinity agonist binding to receptor-G protein complexes containing Gbeta(4). Mol Pharmacol (2002) 1.39
Caring for the residents: the view of two program directors. Ann Thorac Surg (2004) 1.38
Surgical ventricular restoration: the RESTORE Group experience. Heart Fail Rev (2004) 1.37
A novel neutrophil-specific PET imaging agent: cFLFLFK-PEG-64Cu. J Nucl Med (2009) 1.36
Natural killer T cell-derived IL-17 mediates lung ischemia-reperfusion injury. Am J Respir Crit Care Med (2011) 1.35
Activation of adenosine 2A receptors attenuates allograft rejection and alloantigen recognition. J Immunol (2007) 1.32
A2A adenosine receptor activation improves survival in mouse models of endotoxemia and sepsis. J Infect Dis (2004) 1.32
Adenosine A2A agonists in development for the treatment of inflammation. Expert Opin Investig Drugs (2005) 1.31
Anatomy of adenosine A2A receptors in brain: morphological substrates for integration of striatal function. Neurology (2003) 1.31
A2A adenosine receptors on bone marrow-derived cells protect liver from ischemia-reperfusion injury. J Immunol (2005) 1.30
Adenosine A2B receptor blockade slows growth of bladder and breast tumors. J Immunol (2011) 1.28
CD4+ T lymphocytes mediate acute pulmonary ischemia-reperfusion injury. J Thorac Cardiovasc Surg (2009) 1.28
A critical role of the adenosine A2A receptor in extrastriatal neurons in modulating psychomotor activity as revealed by opposite phenotypes of striatum and forebrain A2A receptor knock-outs. J Neurosci (2008) 1.27
CD73 is expressed by human regulatory T helper cells and suppresses proinflammatory cytokine production and Helicobacter felis-induced gastritis in mice. J Infect Dis (2009) 1.25