Published in Circulation on October 08, 2002
Safety Study of Stem Cells Treatment in Diabetic Foot Ulcers | NCT01686139
Intramyocardial Delivery of Autologous Bone Marrow | NCT00820586
Cardiac progenitor cells from adult myocardium: homing, differentiation, and fusion after infarction. Proc Natl Acad Sci U S A (2003) 7.87
Cardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarction. Proc Natl Acad Sci U S A (2005) 6.16
Adult bone marrow cell therapy improves survival and induces long-term improvement in cardiac parameters: a systematic review and meta-analysis. Circulation (2012) 4.56
Unchain my heart: the scientific foundations of cardiac repair. J Clin Invest (2005) 4.25
Cardiac stem cells delivered intravascularly traverse the vessel barrier, regenerate infarcted myocardium, and improve cardiac function. Proc Natl Acad Sci U S A (2005) 3.64
Cell therapy for heart failure: a comprehensive overview of experimental and clinical studies, current challenges, and future directions. Circ Res (2013) 3.56
Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth. Proc Natl Acad Sci U S A (2008) 3.27
Growth of engineered human myocardium with mechanical loading and vascular coculture. Circ Res (2011) 3.25
Adult mesenchymal stem cells and cell-based tissue engineering. Arthritis Res Ther (2002) 2.63
Formation of human myocardium in the rat heart from human embryonic stem cells. Am J Pathol (2005) 2.60
Cells expressing early cardiac markers reside in the bone marrow and are mobilized into the peripheral blood after myocardial infarction. Circ Res (2004) 2.50
Dissecting the molecular relationship among various cardiogenic progenitor cells. Circ Res (2013) 2.06
Interleukin-10 deficiency impairs bone marrow-derived endothelial progenitor cell survival and function in ischemic myocardium. Circ Res (2011) 1.99
Endothelial cells derived from human iPSCS increase capillary density and improve perfusion in a mouse model of peripheral arterial disease. Arterioscler Thromb Vasc Biol (2011) 1.93
Molecular imaging of bone marrow mononuclear cell homing and engraftment in ischemic myocardium. Stem Cells (2007) 1.93
Stem cell therapy is proarrhythmic. Circulation (2009) 1.83
In vitro and in vivo effects of bone marrow stem cells on cardiac structure and function. J Mol Cell Cardiol (2006) 1.81
Autologous bone marrow mononuclear cells enhance recovery after acute ischemic stroke in young and middle-aged rats. J Cereb Blood Flow Metab (2009) 1.80
Stem and progenitor cell-based therapy in ischaemic heart disease: promise, uncertainties, and challenges. Eur Heart J (2011) 1.80
Endothelial dysfunction and diabetes: effects on angiogenesis, vascular remodeling, and wound healing. Int J Vasc Med (2012) 1.70
Endothelial progenitor cells in neovascularization of infarcted myocardium. J Mol Cell Cardiol (2008) 1.69
Stem cell therapy for vascular regeneration: adult, embryonic, and induced pluripotent stem cells. Circulation (2010) 1.67
Human mesenchymal stem cells make cardiac connexins and form functional gap junctions. J Physiol (2004) 1.65
Clinical trials with adult stem/progenitor cells for tissue repair: let's not overlook some essential precautions. Blood (2006) 1.63
Cardiac cell repair therapy: a clinical perspective. Mayo Clin Proc (2009) 1.62
Marrow stromal cells differentiate into vasculature after allogeneic transplantation into ischemic myocardium. Ann Thorac Surg (2011) 1.59
Transplantation of bone marrow-derived very small embryonic-like stem cells attenuates left ventricular dysfunction and remodeling after myocardial infarction. Stem Cells (2008) 1.58
Electrophysiological properties of human mesenchymal stem cells. J Physiol (2003) 1.53
Bone marrow and umbilical cord blood human mesenchymal stem cells: state of the art. Int J Clin Exp Med (2010) 1.53
Adipose-derived mesenchymal stem cells markedly attenuate brain infarct size and improve neurological function in rats. J Transl Med (2010) 1.46
Injection of bone marrow cell extract into infarcted hearts results in functional improvement comparable to intact cell therapy. Mol Ther (2009) 1.45
Cell-based therapies and imaging in cardiology. Eur J Nucl Med Mol Imaging (2005) 1.36
Cell therapy for ischaemic heart disease: focus on the role of resident cardiac stem cells. Neth Heart J (2009) 1.35
Bone marrow stem cell derived paracrine factors for regenerative medicine: current perspectives and therapeutic potential. Bone Marrow Res (2010) 1.34
Long-term myocardial functional improvement after autologous bone marrow mononuclear cells transplantation in patients with ST-segment elevation myocardial infarction: 4 years follow-up. Eur Heart J (2009) 1.34
Comparison of imaging techniques for tracking cardiac stem cell therapy. J Nucl Med (2007) 1.33
Adult bone marrow-derived cells: regenerative potential, plasticity, and tissue commitment. Basic Res Cardiol (2005) 1.32
Bone marrow stem cell mobilization in stroke: a 'bonehead' may be good after all! Leukemia (2011) 1.31
Cell-based therapy for prevention and reversal of myocardial remodeling. Am J Physiol Heart Circ Physiol (2012) 1.31
Imaging: guiding the clinical translation of cardiac stem cell therapy. Circ Res (2011) 1.30
Angiogenic cells can be rapidly mobilized and efficiently harvested from the blood following treatment with AMD3100. Blood (2006) 1.29
Features of cardiomyocyte proliferation and its potential for cardiac regeneration. J Cell Mol Med (2008) 1.27
Results of a phase 1, randomized, double-blind, placebo-controlled trial of bone marrow mononuclear stem cell administration in patients following ST-elevation myocardial infarction. Am Heart J (2010) 1.27
Intracoronary autologous mononucleated bone marrow cell infusion for acute myocardial infarction: results of the randomized multicenter BONAMI trial. Eur Heart J (2010) 1.23
Mesenchymal cell transplantation and myocardial remodeling after myocardial infarction. Circulation (2009) 1.23
Transplanted hematopoietic stem cells demonstrate impaired sarcoglycan expression after engraftment into cardiac and skeletal muscle. J Clin Invest (2004) 1.23
CD34-positive stem cells: in the treatment of heart and vascular disease in human beings. Tex Heart Inst J (2011) 1.21
Combined delivery approach of bone marrow mononuclear stem cells early and late after myocardial infarction: the MYSTAR prospective, randomized study. Nat Clin Pract Cardiovasc Med (2008) 1.20
Bone marrow cells recruited through the neuropilin-1 receptor promote arterial formation at the sites of adult neoangiogenesis in mice. J Clin Invest (2008) 1.20
Genetic engineering of mesenchymal stem cells and its application in human disease therapy. Hum Gene Ther (2010) 1.19
Stem cell therapy: MRI guidance and monitoring. J Magn Reson Imaging (2008) 1.17
Therapeutic myocardial angiogenesis. Microvasc Res (2007) 1.16
Imaging of stem cells using MRI. Basic Res Cardiol (2008) 1.16
Cardiac repair and regeneration: the Rubik's cube of cell therapy for heart disease. Dis Model Mech (2009) 1.16
Peripheral infusion of rat bone marrow derived endothelial progenitor cells leads to homing in acute lung injury. Respir Res (2007) 1.14
Transplantation of autologous mononuclear bone marrow stem cells in patients with peripheral arterial disease (the TAM-PAD study). Clin Res Cardiol (2007) 1.13
Developing mechanistic insights into cardiovascular cell therapy: Cardiovascular Cell Therapy Research Network Biorepository Core Laboratory rationale. Am Heart J (2011) 1.13
Biomaterial strategies for alleviation of myocardial infarction. J R Soc Interface (2011) 1.13
Intramyocardial transplantation of cardiac telocytes decreases myocardial infarction and improves post-infarcted cardiac function in rats. J Cell Mol Med (2014) 1.11
microRNA-150 regulates mobilization and migration of bone marrow-derived mononuclear cells by targeting Cxcr4. PLoS One (2011) 1.10
The bone marrow--cardiac axis of myocardial regeneration. Prog Cardiovasc Dis (2007) 1.10
Concise review: the role of clinical trials in deciphering mechanisms of action of cardiac cell-based therapy. Stem Cells Transl Med (2011) 1.09
Labelling of human mesenchymal stem cells with indium-111 for SPECT imaging: effect on cell proliferation and differentiation. Eur J Nucl Med Mol Imaging (2006) 1.08
Direct injection of autologous mesenchymal stromal cells improves myocardial function. Biochem Biophys Res Commun (2009) 1.08
Randomized transcoronary delivery of CD34(+) cells with perfusion versus stop-flow method in patients with recent myocardial infarction: Early cardiac retention of ⁹⁹(m)Tc-labeled cells activity. J Nucl Cardiol (2010) 1.07
Intracoronary infusion of autologous bone marrow cells and left ventricular function after acute myocardial infarction: a meta-analysis. J Cell Mol Med (2006) 1.07
Adult bone-marrow stem cells and their potential in medicine. J R Soc Med (2004) 1.06
Notch1 in bone marrow-derived cells mediates cardiac repair after myocardial infarction. Circulation (2011) 1.06
Mesenchymal stem cell transplantation improves regional cardiac remodeling following ovine infarction. Stem Cells Transl Med (2012) 1.06
Bone marrow mononuclear stem cells transplanted in rat infarct myocardium improved the electrical conduction without evidence of proarrhythmic effects. Yonsei Med J (2007) 1.05
Targeting angiogenesis to restore the microcirculation after reperfused MI. Nat Rev Cardiol (2009) 1.05
Transplantation of progenitor cells after reperfused acute myocardial infarction: evaluation of perfusion and myocardial viability with FDG-PET and thallium SPECT. Eur J Nucl Med Mol Imaging (2004) 1.04
The winding road to regenerating the human heart. Cardiovasc Pathol (2015) 1.04
Cell therapy attenuates cardiac dysfunction post myocardial infarction: effect of timing, routes of injection and a fibrin scaffold. PLoS One (2009) 1.03
Progenitor cell therapy in a porcine acute myocardial infarction model induces cardiac hypertrophy, mediated by paracrine secretion of cardiotrophic factors including TGFbeta1. Stem Cells Dev (2008) 1.01
Accumulation of fibronectin in the heart after myocardial infarction: a putative stimulator of adhesion and proliferation of adipose-derived stem cells. Cell Tissue Res (2008) 1.01
Coronary vessel development and insight towards neovascular therapy. Int J Exp Pathol (2009) 1.00
A randomized, open-label, multicenter trial for the safety and efficacy of adult mesenchymal stem cells after acute myocardial infarction. J Korean Med Sci (2013) 1.00
Density gradient centrifugation compromises bone marrow mononuclear cell yield. PLoS One (2012) 0.99
Catheter-based transendocardial delivery of autologous bone-marrow-derived mononuclear cells in patients listed for heart transplantation. Tex Heart Inst J (2004) 0.98
Coupling primary and stem cell-derived cardiomyocytes in an in vitro model of cardiac cell therapy. J Cell Biol (2016) 0.97
Myocardial remodeling: cellular and extracellular events and targets. Annu Rev Physiol (2011) 0.97
Early combined treatment with sildenafil and adipose-derived mesenchymal stem cells preserves heart function in rat dilated cardiomyopathy. J Transl Med (2010) 0.96
One-Year Safety Analysis of the COMPARE-AMI Trial: Comparison of Intracoronary Injection of CD133 Bone Marrow Stem Cells to Placebo in Patients after Acute Myocardial Infarction and Left Ventricular Dysfunction. Bone Marrow Res (2011) 0.95
Indium-111 oxine labelling affects the cellular integrity of haematopoietic progenitor cells. Eur J Nucl Med Mol Imaging (2006) 0.95
Changes in expression of genes related to cell proliferation in human mesenchymal stem cells during in vitro culture in comparison with cancer cells. J Artif Organs (2006) 0.95
TLR4 inhibits mesenchymal stem cell (MSC) STAT3 activation and thereby exerts deleterious effects on MSC-mediated cardioprotection. PLoS One (2010) 0.94
Kidney repair and stem cells: a complex and controversial process. Pediatr Nephrol (2011) 0.94
Cell delivery and tracking in post-myocardial infarction cardiac stem cell therapy: an introduction for clinical researchers. Heart Fail Rev (2010) 0.93
Long-term effects of intravitreal injection of GMP-grade bone-marrow-derived CD34+ cells in NOD-SCID mice with acute ischemia-reperfusion injury. Invest Ophthalmol Vis Sci (2012) 0.93
Engineering the heart: evaluation of conductive nanomaterials for improving implant integration and cardiac function. Sci Rep (2014) 0.92
Treatment of bladder dysfunction using stem cell or tissue engineering technique. Korean J Urol (2014) 0.92
Tracking of stem cells in vivo for cardiovascular applications. J Cardiovasc Magn Reson (2014) 0.92
Role of the renin angiotensin system on bone marrow-derived stem cell function and its impact on skeletal muscle angiogenesis. Physiol Genomics (2010) 0.92
Regenerating functional heart tissue for myocardial repair. Cell Mol Life Sci (2012) 0.92
Optimal time for mesenchymal stem cell transplantation in rats with myocardial infarction. J Zhejiang Univ Sci B (2008) 0.92
Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure. Eur Heart J (2016) 0.91
A mammalian microRNA expression atlas based on small RNA library sequencing. Cell (2007) 34.03
Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes. Nat Biotechnol (2008) 6.82
A new human somatic stem cell from placental cord blood with intrinsic pluripotent differentiation potential. J Exp Med (2004) 4.37
Regeneration of human infarcted heart muscle by intracoronary autologous bone marrow cell transplantation in chronic coronary artery disease: the IACT Study. J Am Coll Cardiol (2005) 3.72
The BALANCE Study: clinical benefit and long-term outcome after intracoronary autologous bone marrow cell transplantation in patients with acute myocardial infarction. J Am Coll Cardiol (2009) 2.94
Small molecules enable highly efficient neuronal conversion of human fibroblasts. Nat Methods (2012) 2.64
Safety and efficacy of deep sedation as compared to general anaesthesia in percutaneous mitral valve repair using the MitraClip system. Catheter Cardiovasc Interv (2014) 2.05
Oct4 and its pseudogenes confuse stem cell research. Cell Stem Cell (2007) 1.87
Crucial role of DNA methylation in determination of clonally distributed killer cell Ig-like receptor expression patterns in NK cells. J Immunol (2002) 1.74
Pegylated granulocyte colony-stimulating factor mobilizes CD34+ cells with different stem and progenitor subsets and distinct functional properties in comparison with unconjugated granulocyte colony-stimulating factor. Haematologica (2008) 1.74
Oct4 expression revisited: potential pitfalls for data misinterpretation in stem cell research. Biol Chem (2008) 1.72
Segregation of lipid raft markers including CD133 in polarized human hematopoietic stem and progenitor cells. Blood (2004) 1.67
Cytokine production and hematopoiesis supporting activity of cord blood-derived unrestricted somatic stem cells. Exp Hematol (2005) 1.63
HLA class I/II matching and chronic endothelial cell loss in penetrating normal risk keratoplasty. Acta Ophthalmol Scand (2004) 1.56
Modulation of migratory activity and invasiveness of human glioma spheroids following 5-aminolevulinic acid-based photodynamic treatment. Laboratory investigation. J Neurosurg (2011) 1.45
Improved endothelial function and decreased levels of endothelium-derived microparticles after transcatheter aortic valve implantation. EuroIntervention (2015) 1.45
Influence of percutaneous mitral valve repair using the MitraClip® system on renal function in patients with severe mitral regurgitation. Catheter Cardiovasc Interv (2014) 1.45
Portal application of human unrestricted somatic stem cells to support hepatic regeneration after portal embolization and tumor surgery. ASAIO J (2012) 1.42
Oxygen tension modifies the 'stemness' of human cord blood-derived stem cells. Cytotherapy (2012) 1.41
MicroRNAs MiR-17, MiR-20a, and MiR-106b act in concert to modulate E2F activity on cell cycle arrest during neuronal lineage differentiation of USSC. PLoS One (2011) 1.40
Definition of gene content for nine common group B haplotypes of the Caucasoid population: KIR haplotypes contain between seven and eleven KIR genes. Immunogenetics (2002) 1.37
Asymmetric cell division within the human hematopoietic stem and progenitor cell compartment: identification of asymmetrically segregating proteins. Blood (2007) 1.34
Role of DNA methylation in miR-200c/141 cluster silencing in invasive breast cancer cells. BMC Res Notes (2010) 1.32
Unrelated cord blood transplants in adults with hematologic malignancies. Haematologica (2006) 1.27
Long-term results of allogeneic penetrating limbo-keratoplasty in total limbal stem cell deficiency. Ophthalmology (2004) 1.23
Cord blood comprises antigen-experienced T cells specific for maternal minor histocompatibility antigen HA-1. Blood (2004) 1.23
MicroRNA hsa-miR-135b regulates mineralization in osteogenic differentiation of human unrestricted somatic stem cells. Stem Cells Dev (2010) 1.21
Relevance of C1 and C2 epitopes for hemopoietic stem cell transplantation: role for sequential acquisition of HLA-C-specific inhibitory killer Ig-like receptor. J Immunol (2007) 1.20
Prevention of dipyrone (metamizole) induced inhibition of aspirin antiplatelet effects. Thromb Haemost (2015) 1.14
Functional differences between mesenchymal stem cell populations are reflected by their transcriptome. Stem Cells Dev (2010) 1.14
Stem cells derived from cord blood in transplantation and regenerative medicine. Dtsch Arztebl Int (2009) 1.13
Sp1 as G1 cell cycle phase specific transcription factor in epithelial cells. Oncogene (2002) 1.12
The BCR-ABL1 kinase bypasses selection for the expression of a pre-B cell receptor in pre-B acute lymphoblastic leukemia cells. J Exp Med (2004) 1.11
Elevated serum markers of collagen degradation in patients with mild to moderate dilated cardiomyopathy. Eur J Heart Fail (2002) 1.08
Comparative generation and characterization of pluripotent unrestricted somatic stem cells with mesenchymal stem cells from human cord blood. Exp Hematol (2006) 1.08
Distinct differentiation potential of "MSC" derived from cord blood and umbilical cord: are cord-derived cells true mesenchymal stromal cells? Stem Cells Dev (2012) 1.07
Induction of pluripotency in human cord blood unrestricted somatic stem cells. Exp Hematol (2010) 1.06
Three structurally and functionally divergent kinds of promoters regulate expression of clonally distributed killer cell Ig-like receptors (KIR), of KIR2DL4, and of KIR3DL3. J Immunol (2005) 1.05
Tracing the pre-B to immature B cell transition in human leukemia cells reveals a coordinated sequence of primary and secondary IGK gene rearrangement, IGK deletion, and IGL gene rearrangement. J Immunol (2005) 1.05
T lymphoid differentiation in human bone marrow. Proc Natl Acad Sci U S A (2003) 1.03
NOD-scid IL2rgamma(null) mouse model of human skin transplantation and allograft rejection. Transplantation (2010) 1.03
Rapid and highly efficient gene transfer into natural killer cells by nucleofection. J Immunol Methods (2003) 1.02
Primitive human hematopoietic cells give rise to differentially specified daughter cells upon their initial cell division. Blood (2005) 1.02
Neonatal NK-cell repertoires are functionally, but not structurally, biased toward recognition of self HLA class I. Blood (2011) 1.00
Cellular signaling in normal and cancerous stem cells. Cell Signal (2007) 1.00
Dipyrone (metamizole) can nullify the antiplatelet effect of aspirin in patients with coronary artery disease. J Am Coll Cardiol (2013) 1.00
Nucleolin as activator of human papillomavirus type 18 oncogene transcription in cervical cancer. J Exp Med (2002) 0.98
DLK-1 as a marker to distinguish unrestricted somatic stem cells and mesenchymal stromal cells in cord blood. Stem Cells Dev (2010) 0.97
Nucleofection, an efficient nonviral method to transfer genes into human hematopoietic stem and progenitor cells. Stem Cells Dev (2006) 0.96
MicroRNA-based promotion of human neuronal differentiation and subtype specification. PLoS One (2013) 0.95
Comparison of ectopic bone formation of embryonic stem cells and cord blood stem cells in vivo. Tissue Eng Part A (2010) 0.95
Deficiency of Bruton's tyrosine kinase in B cell precursor leukemia cells. Proc Natl Acad Sci U S A (2005) 0.95
The HOX Code as a "biological fingerprint" to distinguish functionally distinct stem cell populations derived from cord blood. Stem Cell Res (2010) 0.94
Generation and differentiation of microtissues from multipotent precursor cells for use in tissue engineering. Nat Protoc (2011) 0.93
Dendritic cell vaccination in patients with malignant gliomas: current status and future directions. Neurosurgery (2006) 0.92
Cell cycle-controlled interaction of nucleolin with the retinoblastoma protein and cancerous cell transformation. J Biol Chem (2006) 0.92
In vitro differentiation of unrestricted somatic stem cells into functional hepatic-like cells displaying a hepatocyte-like glucose metabolism. J Cell Physiol (2010) 0.92
Toll-like receptor triggering in cord blood mesenchymal stem cells. J Cell Mol Med (2009) 0.92
Unrestricted somatic stem cells from human umbilical cord blood can be differentiated into neurons with a dopaminergic phenotype. Stem Cells Dev (2008) 0.90
Transplantation of human umbilical cord blood-derived adherent progenitors into the developing rodent brain. J Neuropathol Exp Neurol (2005) 0.90
Osteogenic differentiation influences stem cell migration out of scaffold-free microspheres. Tissue Eng Part A (2010) 0.90
Autologous mononuclear stem cell transplantation in patients with peripheral occlusive arterial disease. J Cardiovasc Nurs (2007) 0.89
Hepatocyte growth factor-mediated attraction of mesenchymal stem cells for apoptotic neuronal and cardiomyocytic cells. Cell Mol Life Sci (2009) 0.89
Unrestricted somatic stem cells (USSC) from human umbilical cord blood display uncommitted epigenetic signatures of the major stem cell pluripotency genes. Stem Cell Res (2010) 0.88
Cellular immunity of patients with malignant glioma: prerequisites for dendritic cell vaccination immunotherapy. J Neurosurg (2006) 0.88
Stem cells--clinical application and perspectives. Herz (2002) 0.86
Nucleolin regulates gene expression in CD34-positive hematopoietic cells. J Biol Chem (2007) 0.86
Biocompatibility of osteogenic predifferentiated human cord blood stem cells with biomaterials and the influence of the biomaterial on the process of differentiation. J Biomater Appl (2010) 0.85
The sepsis-related Organ Failure Assessment (SOFA) score is predictive for survival of patients admitted to the intensive care unit following allogeneic blood stem cell transplantation. Ann Hematol (2008) 0.85
Clinical-scale generation of dendritic cells in a closed system. J Immunother (2003) 0.85
Network-like impact of MicroRNAs on neuronal lineage differentiation of unrestricted somatic stem cells from human cord blood. Stem Cells Dev (2011) 0.85
Cutting edge: Dab2 is a FOXP3 target gene required for regulatory T cell function. J Immunol (2009) 0.85
Cord blood for tissue regeneration. J Cell Biochem (2009) 0.84
HLA class I and II matching improves prognosis in penetrating normal-risk keratoplasty. Dev Ophthalmol (2003) 0.84
Accumulation of VEGFR-2+/CD133+ cells and decreased number and impaired functionality of CD34+/VEGFR-2+ cells in patients with SLE. Rheumatology (Oxford) (2010) 0.83
MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord blood. BMC Genomics (2013) 0.83