Published in J Cell Biol on October 07, 2002
Gene expression profiling of lymphoblastoid cell lines from monozygotic twins discordant in severity of autism reveals differential regulation of neurologically relevant genes. BMC Genomics (2006) 1.73
Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPK. EMBO J (2004) 1.68
The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase. EMBO J (2005) 1.52
The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses. EMBO J (2010) 1.36
Genetic variation predicting cisplatin cytotoxicity associated with overall survival in lung cancer patients receiving platinum-based chemotherapy. Clin Cancer Res (2011) 1.32
Semaphorin 4D/Plexin-B1-mediated R-Ras GAP activity inhibits cell migration by regulating beta(1) integrin activity. J Cell Biol (2006) 1.21
The tumor suppressor DAPK inhibits cell motility by blocking the integrin-mediated polarity pathway. J Cell Biol (2006) 1.19
Live free or die: tales of homeless (cells) in cancer. Am J Pathol (2010) 1.15
Integrin signaling, cell survival, and anoikis: distinctions, differences, and differentiation. J Signal Transduct (2011) 1.14
Endothelial apoptosis induced by inhibition of integrins alphavbeta3 and alphavbeta5 involves ceramide metabolic pathways. Blood (2005) 0.95
Protein phosphatase 2A (PP2A) holoenzymes regulate death-associated protein kinase (DAPK) in ceramide-induced anoikis. J Biol Chem (2010) 0.94
Quantitative DNA methylation analysis of candidate genes in cervical cancer. PLoS One (2015) 0.86
KLHL39 suppresses colon cancer metastasis by blocking KLHL20-mediated PML and DAPK ubiquitination. Oncogene (2015) 0.84
DANGER is involved in high glucose-induced radioresistance through inhibiting DAPK-mediated anoikis in non-small cell lung cancer. Oncotarget (2016) 0.82
Serine/threonine kinase 17A is a novel candidate for therapeutic targeting in glioblastoma. PLoS One (2013) 0.82
DAPK1 Signaling Pathways in Stroke: from Mechanisms to Therapies. Mol Neurobiol (2016) 0.80
Ischemia-induced apoptosis of intestinal epithelial cells correlates with altered integrin distribution and disassembly of F-actin triggered by calcium overload. J Biomed Biotechnol (2012) 0.79
New modularity of DAP-kinases: alternative splicing of the DRP-1 gene produces a ZIPk-like isoform. PLoS One (2011) 0.79
Immunopathogenesis of idiopathic nephrotic syndrome with relapse. Semin Immunopathol (2014) 0.78
Demethylation restores SN38 sensitivity in cells with acquired resistance to SN38 derived from human cervical squamous cancer cells. Oncol Rep (2012) 0.78
Upregulation of c-mip is closely related to podocyte dysfunction in membranous nephropathy. Kidney Int (2013) 0.77
Identification of methylation markers for the prediction of nodal metastasis in oral and oropharyngeal squamous cell carcinoma. Epigenetics (2015) 0.77
A soluble truncated cadherin induces breast cancer cell apoptosis and growth inhibition. J Cancer Res Clin Oncol (2006) 0.77
Death Associated Protein Kinase 1 (DAPK1): A Regulator of Apoptosis and Autophagy. Front Mol Neurosci (2016) 0.77
Effect of DAPK1 gene on proliferation, migration, and invasion of carcinoma of pancreas BxPC-3 cell line. Int J Clin Exp Pathol (2014) 0.76
Cul3-KLHL20 ubiquitin ligase: physiological functions, stress responses, and disease implications. Cell Div (2016) 0.76
Identification of Novel Death-Associated Protein Kinase 2 Interaction Partners by Proteomic Screening Coupled with Bimolecular Fluorescence Complementation. Mol Cell Biol (2015) 0.75
CD33, CD96 and Death Associated Protein Kinase (DAPK) Expression Are Associated with the Survival Rate and/or Response to the Chemotherapy in the Patients with Acute Myeloid Leukemia (AML). Med Sci Monit (2017) 0.75
ITIH5 mediates epigenetic reprogramming of breast cancer cells. Mol Cancer (2017) 0.75
p14ARF interacts with the focal adhesion kinase and protects cells from anoikis. Oncogene (2017) 0.75
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Control of adhesion-dependent cell survival by focal adhesion kinase. J Cell Biol (1996) 5.62
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Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis. Science (2001) 4.29
Bidirectional signaling between the cytoskeleton and integrins. Curr Opin Cell Biol (1999) 4.13
Integrin cytoplasmic domains mediate inside-out signal transduction. J Cell Biol (1994) 4.07
Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis. J Cell Biol (1998) 3.52
Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death. Genes Dev (1995) 3.37
DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death. J Cell Biol (2002) 3.32
Regulation of the fibronectin receptor affinity by divalent cations. J Biol Chem (1988) 2.78
DAP-kinase is a Ca2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activity. EMBO J (1997) 2.69
Paxillin interactions. J Cell Sci (2000) 2.67
C-terminal opening mimics 'inside-out' activation of integrin alpha5beta1. Nat Struct Biol (2001) 2.58
Focal adhesion kinase: at the crossroads of signal transduction. J Cell Sci (1997) 2.51
Integrin affinity modulation. Trends Cell Biol (1998) 2.44
DAP kinase links the control of apoptosis to metastasis. Nature (1997) 2.39
Inhibition of pp125FAK in cultured fibroblasts results in apoptosis. J Cell Biol (1996) 2.38
Regulation of integrin alpha 5 beta 1-fibronectin interactions by divalent cations. Evidence for distinct classes of binding sites for Mn2+, Mg2+, and Ca2+. J Biol Chem (1995) 2.35
Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase. J Cell Biol (2000) 2.31
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The integrin beta 1 subunit associates with the vitronectin receptor alpha v subunit to form a novel vitronectin receptor in a human embryonic kidney cell line. J Biol Chem (1990) 2.22
TGF-beta induces apoptosis through Smad-mediated expression of DAP-kinase. Nat Cell Biol (2002) 2.22
The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. Involvement of death receptor-related signaling pathways. J Biol Chem (2000) 2.17
DAP kinase activates a p19ARF/p53-mediated apoptotic checkpoint to suppress oncogenic transformation. Nat Cell Biol (2001) 2.09
ZIP kinase, a novel serine/threonine kinase which mediates apoptosis. Mol Cell Biol (1998) 1.88
DAP-kinase participates in TNF-alpha- and Fas-induced apoptosis and its function requires the death domain. J Cell Biol (1999) 1.85
A transmembrane-anchored chimeric focal adhesion kinase is constitutively activated and phosphorylated at tyrosine residues identical to pp125FAK. J Biol Chem (1994) 1.83
DRAKs, novel serine/threonine kinases related to death-associated protein kinase that trigger apoptosis. J Biol Chem (1998) 1.65
Tissue inhibitor of metalloproteinase-1 inhibits apoptosis of human breast epithelial cells. Cancer Res (1999) 1.56
A structural basis for integrin activation by the cytoplasmic tail of the alpha IIb-subunit. Proc Natl Acad Sci U S A (2000) 1.49
Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation. Mol Cell Biol (2000) 1.44
Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis. Mol Cell Biol (2000) 1.39
Integrin activation by dithiothreitol or Mn2+ induces a ligand-occupied conformation and exposure of a novel NH2-terminal regulatory site on the beta1 integrin chain. J Biol Chem (1998) 1.37
Actin-binding protein-280 binds the stress-activated protein kinase (SAPK) activator SEK-1 and is required for tumor necrosis factor-alpha activation of SAPK in melanoma cells. J Biol Chem (1997) 1.36
Adhesion of T and B lymphocytes to extracellular matrix and endothelial cells can be regulated through the beta subunit of VLA. J Cell Biol (1992) 1.33
Death-associated protein (DAP) kinase plays a central role in ceramide-induced apoptosis in cultured hippocampal neurons. J Biol Chem (2001) 1.26
DAP kinase-a proapoptotic gene that functions as a tumor suppressor. Exp Cell Res (2001) 1.22
DAP-kinase: from functional gene cloning to establishment of its role in apoptosis and cancer. Cell Death Differ (2001) 1.18
The p150-Spir protein provides a link between c-Jun N-terminal kinase function and actin reorganization. Curr Biol (2000) 1.14
Insulin-like growth factor-I-mediated survival from anoikis: role of cell aggregation and focal adhesion kinase. J Cell Physiol (1998) 1.07
Matrix-independent survival of human keratinocytes through an EGF receptor/MAPK-kinase-dependent pathway. Mol Biol Cell (2001) 1.00
DAP kinase activity is critical for C(2)-ceramide-induced apoptosis in PC12 cells. Eur J Biochem (2002) 0.97
TGF-beta induces apoptosis through Smad-mediated expression of DAP-kinase. Nat Cell Biol (2002) 2.22
Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function. Mol Cell (2011) 1.90
Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin. Mol Cell Biol (2004) 1.88
miR-103/107 promote metastasis of colorectal cancer by targeting the metastasis suppressors DAPK and KLF4. Cancer Res (2012) 1.77
Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPK. EMBO J (2004) 1.68
Structural and functional roles of Daxx SIM phosphorylation in SUMO paralog-selective binding and apoptosis modulation. Mol Cell (2011) 1.56
A Cullin3-KLHL20 Ubiquitin ligase-dependent pathway targets PML to potentiate HIF-1 signaling and prostate cancer progression. Cancer Cell (2011) 1.40
The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses. EMBO J (2010) 1.36
Pentoxifylline attenuates tubulointerstitial fibrosis by blocking Smad3/4-activated transcription and profibrogenic effects of connective tissue growth factor. J Am Soc Nephrol (2005) 1.35
Breast tumor kinase phosphorylates p190RhoGAP to regulate rho and ras and promote breast carcinoma growth, migration, and invasion. Cancer Res (2008) 1.26
The tumor suppressor DAPK inhibits cell motility by blocking the integrin-mediated polarity pathway. J Cell Biol (2006) 1.19
Uncoordinated regulation of stress fibers and focal adhesions by DAP kinase. J Cell Sci (2003) 1.18
Daxx mediates the small ubiquitin-like modifier-dependent transcriptional repression of Smad4. J Biol Chem (2005) 1.18
Mechanical strain induces collagenase-3 (MMP-13) expression in MC3T3-E1 osteoblastic cells. J Biol Chem (2004) 1.05
The tumor suppressor DAPK is reciprocally regulated by tyrosine kinase Src and phosphatase LAR. Mol Cell (2007) 1.01
The tumor suppressor death-associated protein kinase targets to TCR-stimulated NF-kappa B activation. J Immunol (2008) 1.01
alpha7 integrin expressing human fetal myogenic progenitors have stem cell-like properties and are capable of osteogenic differentiation. Exp Cell Res (2006) 1.01
Sorting nexin 27 protein regulates trafficking of a p21-activated kinase (PAK) interacting exchange factor (β-Pix)-G protein-coupled receptor kinase interacting protein (GIT) complex via a PDZ domain interaction. J Biol Chem (2011) 1.01
In-vitro effects of dexamethasone on cellular proliferation, apoptosis, and Na+-K+-ATPase activity of bovine corneal endothelial cells. Ocul Immunol Inflamm (2006) 0.97
Effects of brefeldin A-inhibited guanine nucleotide-exchange (BIG) 1 and KANK1 proteins on cell polarity and directed migration during wound healing. Proc Natl Acad Sci U S A (2011) 0.96
Fak56 functions downstream of integrin alphaPS3betanu and suppresses MAPK activation in neuromuscular junction growth. Neural Dev (2008) 0.95
Tumor suppressor death-associated protein kinase is required for full IL-1β production. Blood (2010) 0.94
The Bro1-domain-containing protein Myopic/HDPTP coordinates with Rab4 to regulate cell adhesion and migration. J Cell Sci (2012) 0.91
Landmark identification errors on cone-beam computed tomography-derived cephalograms and conventional digital cephalograms. Am J Orthod Dentofacial Orthop (2011) 0.90
SENP1 deSUMOylates and regulates Pin1 protein activity and cellular function. Cancer Res (2013) 0.90
eIF3k regulates apoptosis in epithelial cells by releasing caspase 3 from keratin-containing inclusions. J Cell Sci (2008) 0.90
Neurofibromin mediates FAK signaling in confining synapse growth at Drosophila neuromuscular junctions. J Neurosci (2012) 0.89
The tumor suppressor DAP-kinase links cell adhesion and cytoskeleton reorganization to cell death regulation. J Biomed Sci (2006) 0.88
PDZ-RhoGEF ubiquitination by Cullin3-KLHL20 controls neurotrophin-induced neurite outgrowth. J Cell Biol (2011) 0.87
Pentoxifylline inhibits platelet-derived growth factor-stimulated cyclin D1 expression in mesangial cells by blocking Akt membrane translocation. Mol Pharmacol (2003) 0.85
Antibiotics induce apoptosis of human peritoneal mesothelial cells. Nephrology (Carlton) (2003) 0.85
Activity-dependent retrograde laminin A signaling regulates synapse growth at Drosophila neuromuscular junctions. Proc Natl Acad Sci U S A (2012) 0.84
Glucosamine promotes osteogenic differentiation of dental pulp stem cells through modulating the level of the transforming growth factor-beta type I receptor. J Cell Physiol (2010) 0.82
The functions and regulations of DAPK in cancer metastasis. Apoptosis (2014) 0.82
Protein kinase C-delta transactivates platelet-derived growth factor receptor-alpha in mechanical strain-induced collagenase 3 (matrix metalloproteinase-13) expression by osteoblast-like cells. J Biol Chem (2009) 0.80
Regulation of inflammation by DAPK. Apoptosis (2014) 0.80
β-PIX controls intracellular viscoelasticity to regulate lung cancer cell migration. J Cell Mol Med (2015) 0.79
C. elegans EIF-3.K promotes programmed cell death through CED-3 caspase. PLoS One (2012) 0.78
Erratum: USP11 regulates PML stability to control Notch-induced malignancy in brain tumours. Nat Commun (2017) 0.75
Relationship of chondrocyte apoptosis to matrix degradation and swelling potential of osteoarthritic cartilage. J Formos Med Assoc (2005) 0.75
Latent membrane protein 1 of Epstein-Barr virus regulates death-associated protein kinase 1 in lymphoblastoid cell line. Virology (2011) 0.75