Published in Exp Cell Res on October 15, 2002
Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activity. J Biol Chem (2007) 4.60
Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells. Cancer Res (2009) 4.24
Migratory neighbors and distant invaders: tumor-associated niche cells. Genes Dev (2008) 2.95
Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration. Immunity (2007) 2.71
EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-Catenin from beta-Catenin and transactivation of beta-Catenin. Mol Cell (2009) 2.50
Cancer stem cells: implications for the progression and treatment of metastatic disease. J Cell Mol Med (2007) 2.29
Pancreatic cancer stem cells and EMT in drug resistance and metastasis. Minerva Chir (2009) 1.79
Decorin is a novel antagonistic ligand of the Met receptor. J Cell Biol (2009) 1.76
Drug discovery approaches to target Wnt signaling in cancer stem cells. Oncotarget (2010) 1.71
Disorders of lung matrix remodeling. J Clin Invest (2004) 1.69
Beta-catenin regulation during the cell cycle: implications in G2/M and apoptosis. Mol Biol Cell (2003) 1.62
Targeting metabolic remodeling in glioblastoma multiforme. Oncotarget (2010) 1.42
Plakoglobin suppresses keratinocyte motility through both cell-cell adhesion-dependent and -independent mechanisms. Proc Natl Acad Sci U S A (2005) 1.29
Non-canonical Wnt signaling and N-cadherin related beta-catenin signaling play a role in mechanically induced osteogenic cell fate. PLoS One (2009) 1.26
Epithelial-mesenchymal transition, TGF-β, and osteopontin in wound healing and tissue remodeling after injury. J Burn Care Res (2012) 1.12
Targeted disruption of the protein kinase SGK3/CISK impairs postnatal hair follicle development. Mol Biol Cell (2004) 1.11
The tumor suppressor Fhit acts as a repressor of beta-catenin transcriptional activity. Proc Natl Acad Sci U S A (2007) 1.11
The carboxyl-terminal domain of atypical protein kinase Czeta binds to ceramide and regulates junction formation in epithelial cells. J Biol Chem (2009) 1.10
Migratory marker expression in fibroblast foci of idiopathic pulmonary fibrosis. Respir Res (2006) 1.10
TGF-beta and BMP7 interactions in tumour progression and bone metastasis. Clin Exp Metastasis (2007) 1.08
Regulation of cell motility by tyrosine phosphorylated villin. Mol Biol Cell (2004) 1.06
Up-regulation of MSX2 enhances the malignant phenotype and is associated with twist 1 expression in human pancreatic cancer cells. Am J Pathol (2008) 1.01
Kupffer cells influence parenchymal invasion and phenotypic orientation, but not the proliferation, of liver progenitor cells in a murine model of liver injury. Am J Pathol (2011) 1.01
APC/β-catenin-rich complexes at membrane protrusions regulate mammary tumor cell migration and mesenchymal morphology. BMC Cancer (2013) 0.98
Single cell adhesion measuring apparatus (SCAMA): application to cancer cell lines of different metastatic potential and voltage-gated Na+ channel expression. Eur Biophys J (2007) 0.95
Translationally controlled tumor protein induces epithelial to mesenchymal transition and promotes cell migration, invasion and metastasis. Sci Rep (2015) 0.88
Cox2 and β-catenin/T-cell factor signaling intestinalize human esophageal keratinocytes when cultured under organotypic conditions. Neoplasia (2011) 0.88
Fibroblasts--a key host cell type in tumor initiation, progression, and metastasis. Ups J Med Sci (2012) 0.88
A novel bidirectional positive-feedback loop between Wnt-β-catenin and EGFR-ERK plays a role in context-specific modulation of epithelial tissue regeneration. J Cell Sci (2014) 0.87
Desmosome regulation and signaling in disease. Cell Tissue Res (2015) 0.84
SMURF1 plays a role in EGF-induced breast cancer cell migration and invasion. Mol Cells (2013) 0.83
Mouse induced pluripotent stem cell microenvironment generates epithelial-mesenchymal transition in mouse Lewis lung cancer cells. Am J Cancer Res (2014) 0.82
Baicalein suppresses metastasis of breast cancer cells by inhibiting EMT via downregulation of SATB1 and Wnt/β-catenin pathway. Drug Des Devel Ther (2016) 0.81
TAp73 protein stability is controlled by histone deacetylase 1 via regulation of Hsp90 chaperone function. J Biol Chem (2013) 0.81
Beta-catenin signalling in mesenchymal islet-derived precursor cells. Cell Prolif (2008) 0.80
Different Effects of BORIS/CTCFL on Stemness Gene Expression, Sphere Formation and Cell Survival in Epithelial Cancer Stem Cells. PLoS One (2015) 0.79
Loss of tumor suppressor Merlin results in aberrant activation of Wnt/β-catenin signaling in cancer. Oncotarget (2016) 0.77
Small molecule inhibitors in acute myeloid leukemia: from the bench to the clinic. Expert Rev Hematol (2014) 0.76
A novel cell-penetrating peptide suppresses breast tumorigenesis by inhibiting β-catenin/LEF-1 signaling. Sci Rep (2016) 0.76
LRP5 and plasma cholesterol levels modulate the canonical Wnt pathway in peripheral blood leukocytes. Immunol Cell Biol (2015) 0.76
Adipocyte-Lineage Cells Support Growth and Dissemination of Multiple Myeloma in Bone. Am J Pathol (2016) 0.75
Multifaceted Interpretation of Colon Cancer Stem Cells. Int J Mol Sci (2017) 0.75
A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Science (2002) 9.59
Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors. Nature (2011) 5.28
Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. Am J Hum Genet (2008) 4.66
Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions. Nat Med (2013) 4.22
Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature (2012) 4.13
Cancer prevention by tea: animal studies, molecular mechanisms and human relevance. Nat Rev Cancer (2009) 3.90
Epidermal growth factor receptor mutations in plasma DNA samples predict tumor response in Chinese patients with stages IIIB to IV non-small-cell lung cancer. J Clin Oncol (2009) 3.58
Incidence and phenotype of inflammatory bowel disease based on results from the Asia-pacific Crohn's and colitis epidemiology study. Gastroenterology (2013) 3.55
Splicing factor SFRS1 recognizes a functionally diverse landscape of RNA transcripts. Genome Res (2008) 3.33
A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination. Mol Cell (2007) 3.23
The membrane-proximal external region of the human immunodeficiency virus type 1 envelope: dominant site of antibody neutralization and target for vaccine design. Microbiol Mol Biol Rev (2008) 3.16
Dynamic characteristics of blood glucose time series during the course of critical illness: effects of intensive insulin therapy and relative association with mortality. Crit Care Med (2010) 3.16
A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA. Blood (2007) 3.09
Quantum-sized carbon dots for bright and colorful photoluminescence. J Am Chem Soc (2006) 3.08
Tumor stromal architecture can define the intrinsic tumor response to VEGF-targeted therapy. Clin Cancer Res (2013) 3.01
Harnessing a high cargo-capacity transposon for genetic applications in vertebrates. PLoS Genet (2006) 2.99
Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease. Neuron (2006) 2.88
Mechanical strain opens connexin 43 hemichannels in osteocytes: a novel mechanism for the release of prostaglandin. Mol Biol Cell (2005) 2.75
Isolation and characterization of human umbilical cord mesenchymal stem cells with hematopoiesis-supportive function and other potentials. Haematologica (2006) 2.75
A novel sRNA component of the carbon storage regulatory system of Escherichia coli. Mol Microbiol (2003) 2.63
Ancient pinnate leaf mimesis among lacewings. Proc Natl Acad Sci U S A (2010) 2.56
Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury. J Cell Biol (2010) 2.40
Image-guided optical spectroscopy provides molecular-specific information in vivo: MRI-guided spectroscopy of breast cancer hemoglobin, water, and scatterer size. Opt Lett (2007) 2.34
Activator control of nucleosome occupancy in activation and repression of transcription. PLoS Biol (2008) 2.29
The plasticity of human maternal brain: longitudinal changes in brain anatomy during the early postpartum period. Behav Neurosci (2010) 2.23
Depolymerization of beta-1,6-N-acetyl-D-glucosamine disrupts the integrity of diverse bacterial biofilms. J Bacteriol (2005) 2.16
Acute phase homocysteine related to severity and outcome of atherothrombotic stroke. Eur J Intern Med (2013) 2.13
c-Jun N-terminal kinase activation mediates downregulation of connexin43 in cardiomyocytes. Circ Res (2002) 2.11
Immune-related microRNAs are abundant in breast milk exosomes. Int J Biol Sci (2011) 2.11
Regulatory circuitry of the CsrA/CsrB and BarA/UvrY systems of Escherichia coli. J Bacteriol (2002) 2.10
Hypertension control in community health centers across China: analysis of antihypertensive drug treatment patterns. Am J Hypertens (2013) 2.08
Streptococcus suis sequence type 7 outbreak, Sichuan, China. Emerg Infect Dis (2006) 2.07
Clinical efficacy of oral ganciclovir for prophylaxis and treatment of recurrent herpes simplex keratitis. Chin Med J (Engl) (2015) 2.04
A RSC/nucleosome complex determines chromatin architecture and facilitates activator binding. Cell (2010) 2.00
B7-h4 is highly expressed in ductal and lobular breast cancer. Clin Cancer Res (2005) 1.94
Functional TRPV4 channels are expressed in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol (2004) 1.92
Sequence diversity of the factor H binding protein vaccine candidate in epidemiologically relevant strains of serogroup B Neisseria meningitidis. J Infect Dis (2009) 1.92
Carbon dots for multiphoton bioimaging. J Am Chem Soc (2007) 1.89
Isolated coronary artery bypass graft combined with bone marrow mononuclear cells delivered through a graft vessel for patients with previous myocardial infarction and chronic heart failure: a single-center, randomized, double-blind, placebo-controlled clinical trial. J Am Coll Cardiol (2011) 1.85
MiR-150 promotes gastric cancer proliferation by negatively regulating the pro-apoptotic gene EGR2. Biochem Biophys Res Commun (2010) 1.80
Musculoskeletal tumors: how to use anatomic, functional, and metabolic MR techniques. Radiology (2012) 1.76
Nucleotide excision repair- and polymerase eta-mediated error-prone removal of mitomycin C interstrand cross-links. Mol Cell Biol (2003) 1.76
Fasudil, a Rho-kinase inhibitor, attenuates glomerulosclerosis in Dahl salt-sensitive rats. J Hypertens (2004) 1.75
Activated beta-catenin induces osteoblast differentiation of C3H10T1/2 cells and participates in BMP2 mediated signal transduction. Biochem Biophys Res Commun (2003) 1.74
The immunomodulatory protein B7-H4 is overexpressed in breast and ovarian cancers and promotes epithelial cell transformation. Exp Cell Res (2005) 1.73
Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β. Nat Neurosci (2013) 1.72
Disruption of Gja8 (alpha8 connexin) in mice leads to microphthalmia associated with retardation of lens growth and lens fiber maturation. Development (2002) 1.72
Estimation of subcellular particle size histograms with electron microscopy for prediction of optical scattering in breast tissue. J Biomed Opt (2007) 1.68
CD44+ CD133+ population exhibits cancer stem cell-like characteristics in human gallbladder carcinoma. Cancer Biol Ther (2010) 1.68
Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals. Cell Res (2010) 1.67
catena-Poly[[aqua-(dipyrido[3,2-a:2',3'-c]phenazine-κN,N)zinc(II)]-μ-pyrazine-2,3-dicarboxyl-ato-κN,O:O]. Acta Crystallogr Sect E Struct Rep Online (2008) 1.65
Metagenome-wide analysis of antibiotic resistance genes in a large cohort of human gut microbiota. Nat Commun (2013) 1.65
High-performance silicon nanohole solar cells. J Am Chem Soc (2010) 1.64
High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells. J Exp Med (2007) 1.63
High expression of p300 has an unfavorable impact on survival in resectable esophageal squamous cell carcinoma. Ann Thorac Surg (2011) 1.60
Comparative metagenomics of microbial communities inhabiting deep-sea hydrothermal vent chimneys with contrasting chemistries. ISME J (2010) 1.60
Endoscopic swept-source optical coherence tomography based on a two-axis microelectromechanical system mirror. J Biomed Opt (2013) 1.59
Altered resting-state amygdala functional connectivity in men with posttraumatic stress disorder. J Psychiatry Neurosci (2012) 1.58
Carbon dots for optical imaging in vivo. J Am Chem Soc (2009) 1.57
Neural dysregulation in posttraumatic stress disorder: evidence for disrupted equilibrium between salience and default mode brain networks. Psychosom Med (2012) 1.57
Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis. Nat Genet (2013) 1.57
Cytogenetic prognostication within medulloblastoma subgroups. J Clin Oncol (2014) 1.56
Tree-structured gatekeeping tests in clinical trials with hierarchically ordered multiple objectives. Stat Med (2007) 1.54
B7-H4 overexpression in ovarian tumors. Gynecol Oncol (2005) 1.51
Identification of nuclear and cytoplasmic mRNA targets for the shuttling protein SF2/ASF. PLoS One (2008) 1.51
Estrogen stimulates the expression of mismatch repair gene hMLH1 in colonic epithelial cells. Cancer Prev Res (Phila) (2010) 1.51
The controlled growth of GaN nanowires. Nano Lett (2006) 1.51
A channel connecting the mother cell and forespore during bacterial endospore formation. Proc Natl Acad Sci U S A (2008) 1.49
Treatment of isolated posterior coronal fracture of the lateral tibial plateau through posterolateral approach for direct exposure and buttress plate fixation. Arch Orthop Trauma Surg (2009) 1.49
Cystatin C-cathepsin B axis regulates amyloid beta levels and associated neuronal deficits in an animal model of Alzheimer's disease. Neuron (2008) 1.49
Targeted genomic sequencing identifies PRRT2 mutations as a cause of paroxysmal kinesigenic choreoathetosis. J Med Genet (2011) 1.49
Spatial periodicity of Escherichia coli K-12 biofilm microstructure initiates during a reversible, polar attachment phase of development and requires the polysaccharide adhesin PGA. J Bacteriol (2005) 1.48
Emergence of ciprofloxacin-resistant Neisseria meningitidis in North America. N Engl J Med (2009) 1.48
Nox1 is over-expressed in human colon cancers and correlates with activating mutations in K-Ras. Int J Cancer (2008) 1.48
Development of the personalized criteria for microscopic review following four different series of hematology analyzer in a Chinese large scale hospital. Chin Med J (Engl) (2010) 1.45
Targeting of antigen to dendritic cells with poly(gamma-glutamic acid) nanoparticles induces antigen-specific humoral and cellular immunity. J Immunol (2007) 1.45
sodC-based real-time PCR for detection of Neisseria meningitidis. PLoS One (2011) 1.45
Genome sequence of the versatile fish pathogen Edwardsiella tarda provides insights into its adaptation to broad host ranges and intracellular niches. PLoS One (2009) 1.44
Genome-wide analysis of aromatase inhibitor-resistant, tamoxifen-resistant, and long-term estrogen-deprived cells reveals a role for estrogen receptor. Cancer Res (2008) 1.44
A preliminary randomized controlled trial of a nurse-delivered medication adherence intervention among HIV-positive outpatients initiating antiretroviral therapy in Beijing, China. AIDS Behav (2011) 1.41
Effects of the Factor Xa Inhibitor, Fondaparinux, on the Stability of Atherosclerotic Lesions in Apolipoprotein E-Deficient Mice. Circ J (2015) 1.41
Mechanisms and clinical significance of quality of final kissing balloon inflation in patients with true bifurcation lesions treated by crush stenting technique. Chin Med J (Engl) (2009) 1.40
Fundamental role of the Rip2/caspase-1 pathway in hypoxia and ischemia-induced neuronal cell death. Proc Natl Acad Sci U S A (2003) 1.40
MD/PhD Training in Canada: Results from a national trainee and program director review. Clin Invest Med (2016) 1.39
A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance. Blood (2013) 1.38
Dose requirements of remifentanil for intubation in nonparalyzed Chinese children. Paediatr Anaesth (2014) 1.38
Imparting functionality to a metal-organic framework material by controlled nanoparticle encapsulation. Nat Chem (2012) 1.36
TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma. Acta Neuropathol (2013) 1.35
Hydrogen-bond-directed supramolecular arrays in 4,4'-bipyridinium tetrachloroterephthalate dihydrate and bis(1,10-phenanthrolinium) tetrachloroterephthalate tetrachloroterephthalic acid trihydrate. Acta Crystallogr C (2009) 1.34
Graphene oxide--MnO2 nanocomposites for supercapacitors. ACS Nano (2010) 1.34
Vascular CD39/ENTPD1 directly promotes tumor cell growth by scavenging extracellular adenosine triphosphate. Neoplasia (2011) 1.34
Antiviral activity of artesunate towards wild-type, recombinant, and ganciclovir-resistant human cytomegaloviruses. J Mol Med (Berl) (2001) 1.33
Fecal microbiota transplantation through mid-gut for refractory Crohn's disease: safety, feasibility, and efficacy trial results. J Gastroenterol Hepatol (2015) 1.33
Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma. Acta Neuropathol (2012) 1.33
SNP interaction detection with Random Forests in high-dimensional genetic data. BMC Bioinformatics (2012) 1.32
Population structure and capsular switching of invasive Neisseria meningitidis isolates in the pre-meningococcal conjugate vaccine era--United States, 2000-2005. J Infect Dis (2010) 1.31
Anti-tumor activity of stability-engineered IgG-like bispecific antibodies targeting TRAIL-R2 and LTbetaR. MAbs (2009) 1.30
What do we know about the mechanisms of aromatase inhibitor resistance? J Steroid Biochem Mol Biol (2006) 1.30